Massive parallel sequencing in forensics: advantages, issues, technicalities, and prospects

In the last decade, next-generation sequencing (NGS) technology, alternatively massive parallel sequencing (MPS), was applied to all fields of biological research. Its introduction to the field of forensics was slower, mainly due to lack of accredited sequencers, kits, and relatively higher sequencing error rates as compared with standardized Sanger sequencing. Currently, a majority of the problematic issues have been solved, which is proven by the body of reports in the literature. Here, we discuss the utility of NGS sequencing in forensics, emphasizing the advantages, issues, the technical aspects of the experiments, commercial solutions, and the potentially interesting applications of MPS.

• Publication year

  2020

• Venue

  Zeitschrift für Rechtsmedizin

• Publication date

  2020-05-25

• Fields of study

  Biology, Medicine, Computer Science

• Identifiers
  DOI 10.1007/s00414-020-02294-0PMID 32451905PMCID 7295846
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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