Excessive deposition of fat in the liver (hepatic steatosis) is frequently accompanied by hepatic insulin resistance. Whether this correlation is due to a causal relationship between the conditions has been the subject of considerable debate, and the literature abounds with conflicting data and theories. Here we provide a perspective by defining the problem and its challenges, analyzing the possible causative relationships, and drawing some conclusions.
The problem of establishing relationships between hepatic steatosis and hepatic insulin resistance.
Robert V Farese,R. Zechner,C. Newgard,T. Walther
Published 2012 in Cell Metabolism
ABSTRACT
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- Publication year
2012
- Venue
Cell Metabolism
- Publication date
2012-05-02
- Fields of study
Biology, Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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