Behandlung des Tourette-Syndroms mit cannabisbasierten Medikamenten

ZUSAMMENFASSUNG Die Behandlung von Patienten mit Gilles-de-la-Tourette-Syndrom (GTS) ist bis heute unbefriedigend, da etablierte Therapien nur zu einer partiellen Reduktion der Tics und nicht zu einer Verbesserung psychiatrischer Komorbiditäten führen. Die medikamentöse Behandlung mit Antipsychotika führt oft zu relevanten Nebenwirkungen. Daher besteht großes Interesse, neue Behandlungsstrategien zu entwickeln. Basierend auf anekdotischen Berichten und kleinen Studien, in denen über positive Effekte durch Cannabis und cannabisbasierte Medikamente bei Patienten mit GTS berichtet wurde, wird in kontrollierten Studien untersucht, ob Medikamente, die durch unterschiedliche Mechanismen zu einer Stimulation des Endocannabinoidsystems führen, wirksam und verträglich in der Therapie von Tics und Komorbiditäten sind. In dieser Übersicht werden bisherige Studienergebnisse vorgestellt. Es werden Hypothesen diskutiert, warum Cannabinoide in der Behandlung des GTS wirksam sein könnten. Schließlich werden praktische Empfehlungen zur Therapie mit cannabisbasierten Medikamenten gegeben.

• Publication year

  2020

• Venue

  Nervenheilkunde

• Publication date

  2020-05-01

• Fields of study

  Not labeled

• Identifiers
  DOI 10.1055/a-1096-4937
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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