Highlights • Lower global oxygen metabolism (CMRO2) in MS patients compared to healthy controls.• CMRO2 predicts increased fatigue and reduced cognitive performance in MS patients.• MS patients with higher CMRO2 have reduced FA in normal-appearing white-matter.• CMRO2 may reflect ongoing MS-related autoimmune activity.
Baseline cerebral metabolism predicts fatigue and cognition in Multiple Sclerosis patients
Kl. West,Dk. Sivakolundu,Gb. Maruthy,Zuppichini,Peiying Liu,B. Thomas,Js. Spence,Hanzhang Lu,D. Okuda,Bart Rypma
Published 2020 in NeuroImage: Clinical
ABSTRACT
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- Publication year
2020
- Venue
NeuroImage: Clinical
- Publication date
2020-05-26
- Fields of study
Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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