Impaired cerebral blood flow in type 2 diabetes mellitus – A comparative study with subjective cognitive decline, vascular dementia and Alzheimer’s disease subjects

Highlights • CBF impairment is found in T2DM and SCD individuals, which might suggest a preclinical stage of dementia.• Comparing to HC, lower CBF in T2DM was due to higher rate of multiple cerebrovascular risk factors.• Unlike T2DM, CBF reduction in AD and VD was due to amyloid deposition and microangiopathy respectively.• Significant negative correlation between adjusted CBF and HbA1c in all cortical regions in healthy control and T2DM.

• Publication year

  2020

• Venue

  NeuroImage: Clinical

• Publication date

  2020-05-28

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.nicl.2020.102302PMID 32521474PMCID 7284123
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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