An update on type 2 diabetes, vascular dementia and Alzheimer's disease.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Experimental Gerontology

• Publication date

  2012-11-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.exger.2012.07.014PMID 22884853
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2011influential reference
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