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Coffee and its Biologically Active Components: Is There a Connection to Breast, Endometrial, and Ovarian Cancer? - a Review

A. Witkowska,I. Mirończuk-Chodakowska,K. Terlikowska,K. Kulesza,M. Zujko

Published 2020 in Polish Journal of Food and Nutrition Sciences

ABSTRACT

Coffee is one of the most popular beverages in the world because of its taste, aroma and stimulating properties, but the perception of coffee as a potentially health-promoting component of the diet is not very high in the global population [Sa moggia & Riedel, 2019]. Except some cases, like pregnancy or sensitivity to some coffee compounds, coffee can offer many benefi cial health effects [Grosso et al., 2016, 2017a; Poole et al., 2017; Wierzejska, 2016]. Interestingly, a recent exploratory study has shown that coffee consumption may modulate the expression of 297 genes in healthy women in different ways [Barnung et al., 2018], thus affecting metabolic and infl ammatory pathways. Several lines of evidence have linked coffee consumption to a reduced risk of cardiovascular diseases [Poole et al., 2017; Rodríguez-Artalejo & López-García, 2018], cancer [Gapstur et al., 2017; Grosso et al., 2017a], neurodegenerative diseases [Liu et al., 2016; Qi & Li, 2014], and diabetes [Ding et al., 2014], as well as to a lower cancer mortality and all-cause mortality [Grosso et al., 2017b; Gunter et al., 2017; Poole et al., 2017]. On a molecular basis, regular coffee consumption preserves the integ-

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