Computational assessment of drug-induced effects on the electrocardiogram: from ion channel to body surface potentials

Understanding drug effects on the heart is key to safety pharmacology assessment and anti‐arrhythmic therapy development. Here our goal is to demonstrate the ability of computational models to simulate the effect of drug action on the electrical activity of the heart, at the level of the ion‐channel, cell, heart and ECG body surface potential.

• Publication year

  2013

• Venue

  British Journal of Pharmacology

• Publication date

  2013-01-16

• Fields of study

  Chemistry, Medicine, Computer Science

• Identifiers
  DOI 10.1111/j.1476-5381.2012.02200.xPMID 22946617PMCID 3579290
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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