Effect of resveratrol on the development of spontaneous mammary tumors in HER‐2/neu transgenic mice

No abstract is available for this paper.

• Publication year

  2005

• Venue

  International Journal of Cancer

• Publication date

  2005-05-20

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1002/ijc.20874PMID 15688416
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• IN HUMAN BREAST CANCER

  2007cited by this paper
• neu Antigen-Negative Variants Can Be Generated after neu-Specific Antibody Therapy in neu Transgenic Mice

  2004cited by this paper
• Resveratrol-induced Apoptosis Is Associated with Fas Redistribution in the Rafts and the Formation of a Death-inducing Signaling Complex in Colon Cancer Cells*

  2003cited by this paper
• Resveratrol activates adenylyl-cyclase in human breast cancer cells: a novel, estrogen receptor-independent cytostatic mechanism.

  2003cited by this paper
• Resveratrol induces growth inhibition and apoptosis in metastatic breast cancer cells via de novo ceramide signaling

  2003cited by this paper
• Resveratrol is a potent inducer of apoptosis in human melanoma cells.

  2003cited by this paper
• Combined effects of resveratrol and paclitaxel on lung cancer cells.

  2003cited by this paper
• Resveratrol blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells.

  2003cited by this paper
• Resveratrol promotes differentiation and induces Fas-independent apoptosis of human medulloblastoma cells.

  2003cited by this paper
• Antitumor and immunomodulatory activity of resveratrol on experimentally implanted tumor of H22 in Balb/c mice.

  2003cited by this paper
• Antitumor effect of resveratrol oligomers against human cancer cell lines and the molecular mechanism of apoptosis induced by vaticanol C.

  2003cited by this paper
• Immunomodulatory activity of resveratrol: discrepant in vitro and in vivo immunological effects.

  2003cited by this paper
• Effect of resveratrol on cell cycle proteins in murine transplantable liver cancer.

  2003cited by this paper
• Inhibitory effect of the peptide epitalon on the development of spontaneous mammary tumors in HER‐2/neu transgenic mice

  2002cited by this paper
• Resveratrol isolated from Polygonum cuspidatum root prevents tumor growth and metastasis to lung and tumor-induced neovascularization in Lewis lung carcinoma-bearing mice.

  2001influential reference
• Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models.

  2001cited by this paper
• Down-Regulation of HER 2 / neu Expression Induces Apoptosis in Human Cancer Cells That Overexpress HER 2 / neu 1

  2000cited by this paper
• p185neu protein is required for tumor and anchorage‐independent growth, not for cell proliferation of transgenic mammary carcinoma

  2000cited by this paper
• DNA vaccination with full-length or truncated Neu induces protective immunity against the development of spontaneous mammary tumors in HER-2/neu transgenic mice

  2000cited by this paper
• Down-regulation of HER2/neu expression induces apoptosis in human cancer cells that overexpress HER2/neu.

  2000cited by this paper
• Resveratrol depresses the growth of colorectal aberrant crypt foci by affecting bax and p21(CIP) expression.

  2000cited by this paper
• Resveratrol acts as a mixed agonist/antagonist for estrogen receptors alpha and beta.

  2000cited by this paper
• Resveratrol, a natural product present in wine, decreases tumour growth in a rat tumour model.

  1999cited by this paper
• Antiproliferative effect of synthetic resveratrol on human breast epithelial cells.

  1998cited by this paper
• Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor.

  1997cited by this paper
• Cancer Chemopreventive Activity of Resveratrol, a Natural Product Derived from Grapes

  1997influential reference
• Activated neu Induces Rapid Tumor Progression (*)

  1996cited by this paper
• Molecular Cloning and Developmental Expression of Mouse p130, a Member of the Retinoblastoma Gene Family (*)

  1996cited by this paper
• A Global Survey ofTrans-Resveratrol Concentrations in Commercial Wines

  1995cited by this paper
• Calculation of lytic units for the expression of cell-mediated cytotoxicity.

  1992cited by this paper
• Optimization of cytotoxic assay by target cell retention of the fluorescent dye carboxyfluorescein diacetate (CFDA) and comparison with conventional 51CR release assay.

  1992cited by this paper
• A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry.

  1991cited by this paper
• Absence of activating transmembrane mutations in the c-erbB-2 proto-oncogene in human breast cancer.

  1990cited by this paper
• Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer.

  1989cited by this paper
• Neu-protein overexpression in breast cancer. Association with comedo-type ductal carcinoma in situ and limited prognostic value in stage II breast cancer.

  1988cited by this paper
• Single-step induction of mammary adenocarcinoma in transgenic mice bearing the activated c-neu oncogene.

  1988cited by this paper
• The MMTV LTR promoter is induced by progesterone and dihydrotestosterone but not by estrogen.

  1988cited by this paper
• Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene.

  1987cited by this paper
• The neu oncogene encodes an epidermal growth factor receptor-related protein

  1986cited by this paper
• Printed in U.S.A. Copyright © 2000 by The Endocrine Society Resveratrol Acts as a Mixed Agonist/Antagonist for

  year unknowncited by this paper

• The Potential of Resveratrol as an Anticancer Agent: Updated Overview of Mechanisms, Applications, and Perspectives

  2025cites this paper
• In Vitro and In Vivo Effects of Resveratrol on Rat Hepatic CYP1A2

  2025cites this paper
• The Role of Resveratrol in Cancer Management: From Monotherapy to Combination Regimens

  2024cites this paper
• Nutrition Intervention and Microbiome Modulation in the Management of Breast Cancer

  2024cites this paper
• Effects of Resveratrol on In Vivo Ovarian Cancer Cells Implanted on the Chorioallantoic Membrane (CAM) of a Chicken Embryo Model

  2024cites this paper
• Inhibitory effect of lomustine on the growth of spontaneous HER2-positive mammary tumors in transgenic mice

  2024cites this paper
• Integrative Bioinformatics Analysis Reveals Potential Target Genes and PTEN Signaling in Breast Cancer and Effect of Zingiber officinale (Ginger) and Allium sativum (Garlic) extract on It

  2024influential citation
• Estudo sobre o Potencial do Resveratrol como Quimioterápico para o Câncer de Mama

  2024cites this paper
• Therapeutic role of resveratrol against hepatocellular carcinoma: a review on its molecular mechanisms of action

  2023cites this paper
• The аntitumor effect of 2-[3-(2-chloroethyl)-3-nitrosoureido]-1,3-propanediol (chlonisol) on the growth of spontaneous mammary tumors in HER-2/neu transgenic mice

  2023cites this paper
• Exploring the role of senescence inducers and senotherapeutics as targets for anticancer natural products.

  2022cites this paper
• The Journey of Resveratrol from Vineyards to Clinics

  2022cites this paper
• Resveratrol Loaded Liposomes Disrupt Cancer Associated Fibroblast Communications within the Tumor Microenvironment to Inhibit Colorectal Cancer Aggressiveness

  2022cites this paper
• Targeting Breast Cancer Stem Cells Using Naturally Occurring Phytoestrogens

  2022cites this paper
• Grape (Vitis vinifera L.) phytochemicals and their biochemical protective mechanisms against leading pathologies

  2022cites this paper
• Polyphenols of the Mediterranean Diet and Their Metabolites in the Prevention of Colorectal Cancer

  2021cites this paper
• Endocrine disrupting chemicals and breast cancer: a systematic review of epidemiological studies

  2021cites this paper
• Resveratrol Enhances Inhibition Effects of Cisplatin on Cell Migration and Invasion and Tumor Growth in Breast Cancer MDA-MB-231 Cell Models In Vivo and In Vitro

  2021cites this paper
• Resveratrol for Cancer Prevention: Current Gaps and Opportunities

  2020cites this paper
• Effect of polyphenols on HER2-positive breast cancer and related miRNAs: Epigenomic regulation.

  2020cites this paper
• Anti-breast cancer activity of resveratrol encapsulated in liposomes.

  2019cites this paper
• Cytotoxic Effect and Mechanisms from Some Plant-Derived Compounds in Breast Cancer

  2019cites this paper
• Resveratrol and other dietary polyphenols are inhibitors of estrogen metabolism in human breast cancer cells.

  2019cites this paper
• Inhibition of VEGFR-2 Phosphorylation and Effects on Downstream Signaling Pathways in Cultivated Human Endothelial Cells by Stilbenes from Vitis Spp.

  2019cites this paper
• Advances on Natural Polyphenols as Anticancer Agents for Skin Cancer.

  2019cites this paper
• Human Health Benefits of Plant Bioactive Compounds

  2019cites this paper
• Plants of the genus Vitis: Phenolic compounds, anticancer properties and clinical relevance

  2019cites this paper
• Breast Cancer and Immunosenescence

  2019cites this paper
• The effects of topical liposomal resveratrol on incisional and excisional wound healing process

  2019cites this paper
• The Potential Use of Resveratrol for Cancer Prevention

  2019cites this paper
• Inducers of Senescence, Toxic Compounds, and Senolytics: The Multiple Faces of Nrf2-Activating Phytochemicals in Cancer Adjuvant Therapy

  2018cites this paper
• Phyto-polyphenols as potential inhibitors of breast cancer metastasis

  2018cites this paper
• Spatial distribution patterns of soil mite communities and their relationships with edaphic factors in a 30-year tillage cornfield in northeast China

  2018cites this paper
• Syddansk Universitet High-dose resveratrol supplementation in obese men Poulsen

  2017cites this paper
• The Role of Resveratrol in Cancer Therapy

  2017influential citation
• Cancer and Chemoprevention: An Overview

  2017cites this paper
• Resveratrol fuels HER2 and ERα-positive breast cancer behaving as proteasome inhibitor

  2017influential citation
• Resveratrol Regulates Colorectal Cancer Cell Invasion by Modulation of Focal Adhesion Molecules

  2017cites this paper
• Developing pedotransfer functions to estimate the S-index for indicating soil quality

  2017cites this paper
• Health Benefits of Grapes Polyphenols

  2017cites this paper
• Chemoprevention by Resveratrol

  2017cites this paper
• A Powerful Analytical Strategy Based on QuEChERS-Dispersive Solid-Phase Extraction Combined with Ultrahigh Pressure Liquid Chromatography for Evaluating the Effect of Elicitors on Biosynthesis of trans-Resveratrol in Grapes

  2016cites this paper
• Anti-metastatic potential of resveratrol and its metabolites by the inhibition of epithelial-mesenchymal transition, migration, and invasion of malignant cancer cells.

  2016cites this paper
• Resveratrol and Its Analogs As Antitumoral Agents For Breast Cancer Treatment.

  2016cites this paper
• Resveratrol for breast cancer prevention and therapy: Preclinical evidence and molecular mechanisms.

  2016cites this paper
• Sirt1 Is Required for Resveratrol-Mediated Chemopreventive Effects in Colorectal Cancer Cells

  2016cites this paper
• Targeting cancer stem cells and signaling pathways by phytochemicals: Novel approach for breast cancer therapy.

  2016cites this paper
• eview argeting cancer stem cells and signaling pathways by hytochemicals : Novel approach for breast cancer therapy

  2016cites this paper
• Synergistic Anticancer Effect of Tocotrienol Combined with Chemotherapeutic Agents or Dietary Components: A Review

  2016cites this paper
• Effects of Mediterranean Diet on the Metabolome

  2016cites this paper
• Targeting HER2 Positive Breast Cancer with Chemopreventive Agents

  2015cites this paper
• Antiangiogenic and antitumor activities of berberine derivative NAX014 compound in a transgenic murine model of HER2/neu-positive mammary carcinoma.

  2015cites this paper
• The chemomodulatory effects of resveratrol and didox on herceptin cytotoxicity in breast cancer cell lines

  2015cites this paper
• Epigenetic Regulation of miRNAs and Breast Cancer Stem Cells

  2015cites this paper
• Resveratrol nanoformulation for cancer prevention and therapy

  2015cites this paper
• The pharmacology of resveratrol in animals and humans.

  2015cites this paper
• Resveratrol as a novel treatment for diseases with mTOR pathway hyperactivation

  2015cites this paper
• Resveratrol: A Sirtuin Activator and The Fountain of Youth

  2015cites this paper
• WOOD BIOCHEMICALS FOR THE PROTECTION OF HEALTH FOCUS ON HEMICELLULOSE, STILBENOIDS AND LIGNANS

  2015cites this paper
• Resveratrol induces chemosensitization to 5-fluorouracil through up-regulation of intercellular junctions, Epithelial-to-mesenchymal transition and apoptosis in colorectal cancer.

  2015cites this paper
• Bio-Evaluation of 99m tc Resveratrol in Targeting Chemically Induced Mammary Tumors in Rats

  2014cites this paper
• Effects of resveratrol and irradiation upon oral squamous cell carcinoma cells

  2014cites this paper
• Resveratrol and cancer: focus on in vivo evidence

  2014cites this paper
• Resveratrol attenuates high-fat diet-induced disruption of the blood-brain barrier and protects brain neurons from apoptotic insults.

  2014cites this paper
• The Multiple Mechanisms of Cell Death Triggered by Resveratrol in Lymphoma and Leukemia

  2014cites this paper
• An Organ System Approach to Explore the Antioxidative, Anti-Inflammatory, and Cytoprotective Actions of Resveratrol

  2014cites this paper
• Polyphenol-Mediated In Vivo Cellular Responses during Carcinogenesis

  2014cites this paper
• Cellular, Molecular, and Biological Perspective of Polyphenols in Chemoprevention and Therapeutic Adjunct in Cancer 71

  2013cites this paper
• Endocrine Disruptors and the Breast: Early Life Effects and Later Life Disease

  2013cites this paper
• Impact of cellular senescence in aging and cancer.

  2013cites this paper
• Nutlin-3a, an MDM2 antagonist and p53 activator, helps to preserve the replicative potential of cancer cells treated with a genotoxic dose of resveratrol

  2013cites this paper
• Resveratrol in metabolic health: an overview of the current evidence and perspectives

  2013cites this paper
• Effect of Dietary Resveratrol in the Treatment of Cancer

  2013cites this paper
• Effect of annatto-tocotrienols supplementation on the development of mammary tumors in HER-2/neu transgenic mice.

  2013cites this paper
• Anticancer bioactivity of compounds from medicinal plants used in European medieval traditions.

  2013influential citation
• Wybrane ksenoestrogeny i ich wpływ na zdrowie człowieka

  2013cites this paper
• Resveratrol diminishes platelet aggregation and increases susceptibility of K562 tumor cells to natural killer cells.

  2013cites this paper
• Antitumor effect of novel berberine derivatives in breast cancer cells.

  2013cites this paper
• The interface between plant metabolic engineering and human health.

  2013cites this paper
• High-Dose Resveratrol Supplementation in Obese Men An Investigator-Initiated, Randomized, Placebo-Controlled Clinical Trial of Substrate Metabolism, Insulin Sensitivity, and Body Composition

  2013cites this paper
• Resveratrol and Clinical Trials: The Crossroad from In Vitro Studies to Human Evidence

  2013cites this paper
• High-Dose Resveratrol Supplementation in Obese Men

  2013cites this paper
• Potential of grape polyphenols as breast cancer therapeutics

  2013cites this paper
• Epigenetic regulation of breast cancer type-1 gene by the activated aromatic hydrocarbon receptor and the preventative effects of resveratrol

  2012cites this paper
• Dietary and Non-dietary Phytochemicals in Cancer Control

  2012cites this paper
• Bioactive compounds in wine: Resveratrol, hydroxytyrosol and melatonin: A review

  2012cites this paper
• Resveratrol sensitized leukemia stem cell-like KG-1a cells to cytokine-induced killer cells-mediated cytolysis through NKG2D ligands and TRAIL receptors

  2012cites this paper
• Endocrine-active chemicals in mammary cancer causation and prevention.

  2012cites this paper
• Modulation of angiogenesis by dietary phytoconstituents in the prevention and intervention of breast cancer.

  2012cites this paper
• What Is New for an Old Molecule? Systematic Review and Recommendations on the Use of Resveratrol

  2011cites this paper
• Resveratrol and its analogues: promising antitumor agents.

  2011cites this paper
• Diverse animal models to examine potential role(s) and mechanism of endocrine disrupting chemicals on the tumor progression and prevention: Do they have tumorigenic or anti-tumorigenic property?

  2011cites this paper
• Investigating the ERBB Protein Interactome

  2011cites this paper
• Quantitation of resveratrol in red wines by means of stable isotope dilution analysis-ultra-performance liquid chromatography-Quan-time-of-flight mass spectrometry and cross validation.

  2011cites this paper
• Resveratrol Attenuates Oxidized LDL-Evoked Lox-1 Signaling and Consequently Protects against Apoptotic Insults to Cerebrovascular Endothelial Cells

  2011cites this paper
• Subchronic oral toxicity and cardiovascular safety pharmacology studies of resveratrol, a naturally occurring polyphenol with cancer preventive activity.

  2011cites this paper
• New method for determination of (E)-resveratrol in wine based on microextraction using packed sorbent and ultra-performance liquid chromatography.

  2011cites this paper
• Targeting Cell Signaling and Apoptotic Pathways by Dietary Agents: Role in the Prevention and Treatment of Cancer

  2011cites this paper
• Resveratrol treatment induces redox stress in red blood cells: a possible role of caspase 3 in metabolism and anion transport

  2010cites this paper
• Mammary and Prostate Cancer Chemoprevention and Mechanisms of Action of Resveratrol and Genistein in Rodent Models

  2010cites this paper