NBR1 co-operates with p62 in selective autophagy of ubiquitinated targets

No abstract is available for this paper.

• Publication year

  2009

• Venue

  Autophagy

• Publication date

  2009-07-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.4161/auto.5.5.8566PMID 19398892
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• No references are available for this paper.

• HIV-1 Vpr is targeted for degradation by autophagy.

  2026cites this paper
• A Cancer-Specific Antigen Drives Histone Acetylation by Stabilizing the Acetyltransferases

  2025cites this paper
• Autophagy cargo profiles in skeletal muscle during starvation and exercise

  2025cites this paper
• CUL1-neddylation contributes to K29-linked ubiquitination on p27 for autophagic degradation in sorafenib-resistant liver cancer

  2025cites this paper
• The predominant role of p62/SQSTM1 over NBR1 in methylmercury-induced cytotoxicity and cellular defense.

  2025cites this paper
• The Role of WIPI2, ATG16L1 and ATG12-ATG5 in selective and nonselective autophagy.

  2025cites this paper
• Hydrophobic tagging: A promising paradigm for targeted protein degradation

  2025cites this paper
• Selective mitophagy activation and protein aggregate accumulation in MTMR5/SBF1-deficient fibroblasts.

  2025cites this paper
• Current Understanding of Protein Aggregation in Neurodegenerative Diseases

  2025cites this paper
• Targeting macroautophagy to combat neurodegenerative disease: strategies and considerations

  2025cites this paper
• The molecular mechanisms of mitochondrial dynamics and mitophagy and their complex association with cancer drug resistance

  2025cites this paper
• Selective Autophagy in Kidney Diseases: The Tip of the Iceberg

  2025cites this paper
• Autophagy-targeted NBR1–p62/SQSTM1 complexes promote breast cancer metastasis by sequestering ITCH

  2025cites this paper
• Autophagy modulates Arabidopsis male gametophyte fertility and controls actin organization

  2024cites this paper
• Dual roles of AtNBR1 in regulating selective autophagy via liquid-liquid phase separation and recognition of non-ubiquitinated substrates in Arabidopsis

  2024cites this paper
• The LC3-interacting region of NBR1 is a protein interaction hub enabling optimal flux

  2024cites this paper
• Suppressed basal mitophagy drives cellular aging phenotypes that can be reversed by a p62-targeting small molecule.

  2024cites this paper
• Research Progress of Mitophagy in Alzheimer's Disease.

  2024cites this paper
• Calorie restriction modulates mitochondrial dynamics and autophagy in leukocytes of patients with obesity.

  2024cites this paper
• Evaluation of Teneligliptin and Retagliptin on the Clearance of Melanosome by Melanophagy in B16F1 Cells

  2024cites this paper
• Enhanced liquidity of p62 droplets mediated by Smurf1 links Nrf2 activation and autophagy

  2023cites this paper
• Deregulation of mTORC1-TFEB axis in human iPSC model of GBA1-associated Parkinson’s disease

  2023cites this paper
• Autophagy‐targeted nanoparticles in breast carcinoma: A systematic review

  2023cites this paper
• Molecular mechanisms in chloroquine‐exposed muscle cells elucidated by combined proteomic and microscopic studies

  2023cites this paper
• K63-linked ubiquitin chains are a global signal for endocytosis and contribute to selective autophagy in plants.

  2023cites this paper
• The Role of Retinal Pigment Epithelial Cells in Age-Related Macular Degeneration: Phagocytosis and Autophagy

  2023cites this paper
• LLPS of SQSTM1/p62 and NBR1 as outcomes of lysosomal stress response limits cancer cell metastasis

  2023cites this paper
• CSFV restricts necroptosis to sustain infection by inducing autophagy/mitophagy-targeted degradation of RIPK3

  2023cites this paper
• The autophagy of stress granules

  2023cites this paper
• Quantitative proteomic analysis reveals the effects of mu opioid agonists on HT22 cells

  2023cites this paper
• Hydrophobic tag-based protein degradation: Development, opportunity and challenge.

  2023cites this paper
• P62/SQSTM1 binds with claudin-2 to target for selective autophagy in stressed intestinal epithelium

  2023cites this paper
• Autophagy preferentially degrades non-fibrillar polyQ aggregates

  2023cites this paper
• Selectivity and trafficking of autophagic cargoes

  2022cites this paper
• A bacterial effector counteracts host autophagy by promoting degradation of an autophagy component

  2022cites this paper
• The molecular regulation of autophagy in antimicrobial immunity

  2022cites this paper
• Involvement of molecular chaperone in protein-misfolding brain diseases.

  2022cites this paper
• Cargo receptors and adaptors for selective autophagy in plant cells

  2022cites this paper
• Integrated proteomics reveals the landscape of autophagy degradation in human neurons and autophagy receptors regulating neuronal activity

  2022cites this paper
• Oligomerization of Selective Autophagy Receptors for the Targeting and Degradation of Protein Aggregates

  2021cites this paper
• Genetic Determinants of Paget’s Disease of Bone

  2021cites this paper
• Molecular insights into plant desiccation tolerance: transcriptomics, proteomics and targeted metabolite profiling in Craterostigma plantagineum

  2021cites this paper
• Autophagy-Associated IL-15 Production Is Involved in the Pathogenesis of Leprosy Type 1 Reaction

  2021cites this paper
• Sequestsome-1/p62-targeted small molecules for pancreatic cancer therapy.

  2021cites this paper
• Self-ubiquitination of a pathogen type-III effector traps and blocks the autophagy machinery to promote disease

  2021cites this paper
• Pro-Tumoral Functions of Autophagy Receptors in the Modulation of Cancer Progression

  2021influential citation
• Molecular insights into plant desiccation tolerance: transcriptomics, proteomics and targeted metabolite profiling in <fi>Craterostigma plantagineum</fi>

  2021cites this paper
• A brief overview of BNIP3L/NIX receptor‐mediated mitophagy

  2021cites this paper
• Insights into the Pathogenesis of Neurodegenerative Diseases: Focus on Mitochondrial Dysfunction and Oxidative Stress

  2021cites this paper
• Biomarkers of Autophagy.

  2021cites this paper
• The E2 ubiquitin-conjugating enzyme UbcH5c: an emerging target in cancer and immune disorders.

  2020cites this paper
• Conidiobolus coronatus induces oxidative stress and autophagy response in Galleria mellonella larvae

  2020cites this paper
• NBR1‐mediated p62‐liquid droplets enhance the Keap1‐Nrf2 system

  2020cites this paper
• Implications of Selective Autophagy Dysfunction for ALS Pathology

  2020cites this paper
• Targeting Aggrephagy for the Treatment of Alzheimer’s Disease

  2020cites this paper
• Emendation of autophagic dysfuction in neurological disorders: a potential therapeutic target

  2020cites this paper
• The Role of Selective Protein Degradation in the Regulation of Iron and Sulfur Homeostasis in Plants

  2020cites this paper
• Organismal Protein Homeostasis Mechanisms

  2020cites this paper
• Loss of TAX1BP1-Directed Autophagy Results in Protein Aggregate Accumulation in the Brain.

  2020cites this paper
• The Roles of Ubiquitin in Mediating Autophagy

  2020cites this paper
• HIV-1 Nef counteracts autophagy restriction by enhancing the association between BECN1 and its inhibitor BCL2 in a PRKN-dependent manner

  2020cites this paper
• Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors.

  2020cites this paper
• The chlamydial deubiquitinase Cdu1 supports recruitment of Golgi vesicles to the inclusion

  2020cites this paper
• GABARAPs and LC3s have opposite roles in regulating ULK1 for autophagy induction

  2020cites this paper
• Broad and Complex Roles of NBR1-Mediated Selective Autophagy in Plant Stress Responses

  2020cites this paper
• BAG6 deficiency induces mis‐distribution of mitochondrial clusters under depolarization

  2019cites this paper
• An antibody for analysis of autophagy induction

  2019cites this paper
• Targeting Autophagy to Overcome Human Diseases

  2019cites this paper
• Crosstalk between Autophagy and Type I Interferon Responses in Innate Antiviral Immunity

  2019cites this paper
• Atg7-dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia

  2019cites this paper
• Targeting autophagy potentiates antitumor activity of Met-TKIs against Met-amplified gastric cancer

  2019cites this paper
• The Roles of Ubiquitin-Binding Protein Shuttles in the Degradative Fate of Ubiquitinated Proteins in the Ubiquitin-Proteasome System and Autophagy

  2019cites this paper
• Sequestosome 1/p62-related pathways as therapeutic targets in hepatocellular carcinoma

  2019cites this paper
• Negative regulation of autophagy by UBA6-BIRC6–mediated ubiquitination of LC3

  2019influential citation
• mTOR hyperactivity mediates lysosomal dysfunction in Gaucher's disease iPSC-neuronal cells

  2019cites this paper
• Selective autophagic clearance of protein aggregates is mediated by the autophagy receptor, TAX1BP1

  2019cites this paper
• La inactivación de Pim quinasas potencia la muerte celular mediada por el ligando de muerte trail en glioblastoma

  2019cites this paper
• NBR1-mediated p62-liquid droplets enhance the Keap1-Nrf2 system

  2019influential citation
• L'autophagie induite par les glycoprotéines de l'enveloppe du VIH-1 dégrade les peroxysomes : rôle dans la mort des lymphocytes T CD4 non infectés

  2019cites this paper
• Neuronal Proteomic Analysis of the Ubiquitinated Substrates of the Disease-Linked E3 Ligases Parkin and Ube3a

  2018cites this paper
• Autophagy in Negative-Strand RNA Virus Infection

  2018cites this paper
• p62/SQSTM1 – steering the cell through health and disease

  2018cites this paper
• Nitric oxide contributes to protein homeostasis by S-nitrosylations of the chaperone HSPA8 and the ubiquitin ligase UBE2D

  2018cites this paper
• Peroxisomes and cancer: The role of a metabolic specialist in a disease of aberrant metabolism.

  2018cites this paper
• Role of Optineurin in the Mitochondrial Dysfunction: Potential Implications in Neurodegenerative Diseases and Cancer

  2018influential citation
• Neurodegenerative Diseases and Autophagy

  2018cites this paper
• Investigating the neuroprotective role of OGA inhibition by Thiamet-G against Alzheimer\'s disease

  2018cites this paper
• Metabolic reprogramming of the tumor microenvironment by p62 and its partners.

  2018cites this paper
• Myocardial Insulin Signaling and Autophagy

  2018cites this paper
• TRPML1: Role In Autophagy And Potential Target To Treat Lysosomal Storage Disorders

  2018influential citation
• Antitumor Activity of Copper (I)-Nicotinate Complex and Autophagy Modulation in HCC1806 Breast Cancer Cells.

  2017cites this paper
• Role of Autophagy in Regulating Cyclin A2 Degradation: Live-Cell Imaging

  2017cites this paper
• Mapping of Nuclear Export Signals and domains mediating aggregation of NBR1

  2017cites this paper
• Involvement of the p62/NRF2 signal transduction pathway on erythrophagocytosis

  2017cites this paper
• NBR 1 and KIF 14 Downstream of the Mammarian Target of Rapamycin Pathway Predict Recurrence in Nonmuscle Invasive Low Grade Urothelial Carcinoma of the Bladder

  2017cites this paper
• FKBP8 and the autophagy-inducing Class-III PI3K ComplexRoles of LIR dependent interactions

  2017cites this paper
• Proteostasis of Huntingtin in Health and Disease

  2017cites this paper
• Relationship between the proteasomal system and autophagy.

  2017cites this paper
• Analysis of Phosphatidylinositol Metabolism and ER-Mitochondria Contact Sites in the PINK1/Parkin Pathway

  2017cites this paper
• Systematic Analysis of Human Cells Lacking ATG8 Proteins Uncovers Roles for GABARAPs and the CCZ1/MON1 Regulator C18orf8/RMC1 in Macroautophagic and Selective Autophagic Flux

  2017cites this paper