Prediction of stillbirth: an umbrella review of evaluation of prognostic variables

Stillbirth accounts for over 2 million deaths a year worldwide and rates remains stubbornly high. Multivariable prediction models may be key to individualised monitoring, intervention or early birth in pregnancy to prevent stillbirth.

• Publication year

  2020

• Venue

  BJOG: an International Journal of Obstetrics and Gynaecology

• Publication date

  2020-09-15

• Fields of study

  Medicine

• Identifiers
  DOI 10.1111/1471-0528.16510PMID 32931648
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Maternal hemoglobin concentrations across pregnancy and maternal and child health: a systematic review and meta‐analysis

  2019cited by this paper
• Stillbirth and associated perinatal outcomes in obstetric cholestasis: a systematic review and meta-analysis of observational studies

  2019cited by this paper
• Effects of hemoglobin levels during pregnancy on adverse maternal and infant outcomes: a systematic review and meta‐analysis

  2019cited by this paper
• Risks of stillbirth and neonatal death with advancing gestation at term: A systematic review and meta-analysis of cohort studies of 15 million pregnancies

  2019cited by this paper
• Association of adverse perinatal outcomes of intrahepatic cholestasis of pregnancy with biochemical markers: results of aggregate and individual patient data meta-analyses

  2019cited by this paper
• Biochemical tests of placental function versus ultrasound assessment of fetal size for stillbirth and small-for-gestational-age infants.

  2019cited by this paper
• Re-evaluating the role of cerebroplacental ratio in predicting adverse perinatal outcome.

  2019cited by this paper
• Management and outcomes of pregnancy with or without lupus nephritis: a systematic review and meta-analysis

  2018cited by this paper
• Feasibility of using self‐reported ethnicity in pregnancy according to the gestation‐related optimal weight classification: a cross‐sectional study

  2018cited by this paper
• Understanding the associations and significance of fetal movements in overweight or obese pregnant women: a systematic review

  2018cited by this paper
• Risk of stillbirth, preterm delivery, and fetal growth restriction following exposure in a previous birth: systematic review and meta‐analysis

  2018cited by this paper
• Risk of Stillbirth, Preterm Delivery, and Fetal Growth Restriction Following Exposure in a Previous Birth: Systematic Review and Meta-analysis

  2018cited by this paper
• The intrapartum and perinatal risks of sleep‐disordered breathing in pregnancy: a systematic review and metaanalysis

  2018cited by this paper
• The effect of paternal factors on perinatal and paediatric outcomes: a systematic review and meta-analysis

  2018cited by this paper
• Obstetrical outcome in women with endometriosis including spontaneous hemoperitoneum and bowel perforation: a systematic review.

  2018cited by this paper
• Prognostic accuracy of cerebroplacental ratio and middle cerebral artery Doppler for adverse perinatal outcome: systematic review and meta‐analysis

  2018cited by this paper
• Long-term risks and benefits associated with cesarean delivery for mother, baby, and subsequent pregnancies: Systematic review and meta-analysis

  2018cited by this paper
• Systematic review of maternal Placental Growth Factor levels in late pregnancy as a predictor of adverse intrapartum and perinatal outcomes.

  2018cited by this paper
• Minimum sample size for developing a multivariable prediction model: Part I – Continuous outcomes

  2018cited by this paper
• Predictive accuracy of cerebroplacental ratio for adverse perinatal and neurodevelopmental outcomes in suspected fetal growth restriction: systematic review and meta‐analysis

  2018cited by this paper
• Maternal sleep during pregnancy and poor fetal outcomes: A scoping review of the literature with meta-analysis.

  2018cited by this paper
• Risk of spontaneous preterm birth in singleton pregnancies conceived after IVF/ICSI treatment: meta‐analysis of cohort studies

  2018cited by this paper
• Effects of maternal anthropometrics on pregnancy outcomes in South Asian women: a systematic review

  2018cited by this paper
• Systematic review of the potential adverse effects of caffeine consumption in healthy adults, pregnant women, adolescents, and children.

  2017cited by this paper
• Maternal, Labor, Delivery, and Perinatal Outcomes Associated with Placental Abruption: A Systematic Review

  2017cited by this paper
• Pregnancy outcomes in patients with acute kidney injury during pregnancy: a systematic review and meta-analysis

  2017cited by this paper
• Quantitative assessment of the effect of pre-gestational diabetes and risk of adverse maternal, perinatal and neonatal outcomes

  2017cited by this paper
• A stillbirth calculator: Development and internal validation of a clinical prediction model to quantify stillbirth risk

  2017cited by this paper
• Customised and Noncustomised Birth Weight Centiles and Prediction of Stillbirth and Infant Mortality and Morbidity: A Cohort Study of 979,912 Term Singleton Pregnancies in Scotland

  2017cited by this paper
• Advanced maternal age and adverse pregnancy outcomes: A systematic review and meta-analysis

  2017cited by this paper
• Maternal vitamin D insufficiency and risk of adverse pregnancy and birth outcomes: A systematic review and meta-analysis of longitudinal studies

  2017cited by this paper
• Bipolar disorder in pregnancy and childbirth: a systematic review of outcomes

  2016cited by this paper
• National, regional, and worldwide estimates of stillbirth rates in 2015, with trends from 2000: a systematic analysis.

  2016cited by this paper
• Association between perinatal outcomes and maternal pre‐pregnancy body mass index

  2016cited by this paper
• Which one has a better obstetric and perinatal outcome in singleton pregnancy, IVF/ICSI or FET?: a systematic review and meta-analysis

  2016cited by this paper
• Predictive accuracy of second‐trimester uterine artery Doppler indices for stillbirth: a systematic review and meta‐analysis

  2016influential reference
• Association between primary Sjögren’s syndrome and pregnancy complications: a systematic review and meta-analysis

  2016cited by this paper
• Predicting stillbirth in a low resource setting

  2016cited by this paper
• Systematic Review and Meta-Analyses of Perinatal Death and Maternal Exposure to Tobacco Smoke During Pregnancy.

  2016cited by this paper
• Prediction of stillbirth from maternal factors, fetal biometry and uterine artery Doppler at 19–24 weeks

  2016cited by this paper
• Environmental risk factors and Parkinson's disease: An umbrella review of meta-analyses.

  2016cited by this paper
• Prognostic models in obstetrics: available, but far from applicable.

  2016cited by this paper
• Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): the TRIPOD Statement

  2015cited by this paper
• Maternal Smokeless Tobacco Use in Pregnancy and Adverse Health Outcomes in Newborns: A Systematic Review.

  2015cited by this paper
• Adverse maternal and perinatal outcomes in pregnant women with sickle cell disease: systematic review and meta-analysis.

  2015cited by this paper
• Effect of Ebola Progression in Liberia

  2015cited by this paper
• Research priorities for stillbirth: process overview and results from UK Stillbirth Priority Setting Partnership

  2015cited by this paper
• Risks associated with obesity in pregnancy, for the mother and baby: a systematic review of reviews

  2015cited by this paper
• Maternal smoking and the risk of still birth: systematic review and meta-analysis

  2015cited by this paper
• First‐ and second‐trimester tests to predict stillbirth in unselected pregnant women: a systematic review and meta‐analysis

  2015influential reference
• Introduction of a nomogram for predicting adverse pregnancy outcomes based on maternal serum markers in the quad screen test

  2015cited by this paper
• Risk of recurrent stillbirth: systematic review and meta-analysis

  2015cited by this paper
• Maternal BodyMass Index and the Risk of Fetal Death , Stillbirth , and Infant Death

  2014cited by this paper
• Deprived neighborhoods and adverse perinatal outcome: a systematic review and meta‐analysis

  2014cited by this paper
• Caffeine intake during pregnancy and adverse birth outcomes: a systematic review and dose–response meta-analysis

  2014cited by this paper
• Elevated risk of stillbirth in males: systematic review and meta-analysis of more than 30 million births

  2014cited by this paper
• A Meta-Analysis of Selected Maternal and Fetal Factors for Perinatal Mortality

  2014cited by this paper
• Maternal body mass index and the risk of fetal death, stillbirth, and infant death: a systematic review and meta-analysis.

  2014cited by this paper
• A Meta-Analysis of Socio-Demographic Factors for Perinatal Mortality in Developing Countries: A Subgroup Analysis of the National Surveys and Small Scale Studies

  2014cited by this paper
• Causes of and factors associated with stillbirth in low‐ and middle‐income countries: a systematic literature review

  2014cited by this paper
• Incidence of adverse outcomes associated with gestational diabetes mellitus in low‐ and middle‐income countries

  2013cited by this paper
• An Update on Diabetic Women Obstetrical Outcomes Linked to Preconception and Pregnancy Glycemic Profile: A Systematic Literature Review

  2013cited by this paper
• Association Between Stillbirth and Risk Factors Known at Pregnancy Confirmation

  2013cited by this paper
• Caesarean Delivery and Subsequent Stillbirth or Miscarriage: Systematic Review and Meta-Analysis

  2013cited by this paper
• The risk of congenital malformations, perinatal mortality and neonatal hospitalisation among pregnant women with asthma: a systematic review and meta‐analysis

  2013cited by this paper
• Individual participant data meta-analysis of prognostic factor studies: state of the art?

  2012cited by this paper
• Combinations of maternal serum markers to predict preeclampsia, small for gestational age, and stillbirth: a systematic review.

  2012cited by this paper
• The impact of early age at first childbirth on maternal and infant health.

  2012cited by this paper
• Social inequality and infant health in the UK: systematic review and meta-analyses

  2012cited by this paper
• Major risk factors for stillbirth in high-income countries: a systematic review and meta-analysis.

  2011cited by this paper
• Association between stillbirth and risk factors known at pregnancy confirmation.

  2011cited by this paper
• Pregnancy and neonatal outcomes of aboriginal women: a systematic review and meta-analysis.

  2011cited by this paper
• Secondhand Smoke and Adverse Fetal Outcomes in Nonsmoking Pregnant Women: A Meta-analysis

  2011cited by this paper
• Advanced maternal age and adverse perinatal outcome: a review of the evidence.

  2011cited by this paper
• The association between antiphospholipid antibodies and placenta mediated complications: a systematic review and meta-analysis.

  2011cited by this paper
• How to obtain the P value from a confidence interval

  2011cited by this paper
• Pregnancy outcomes in women with chronic kidney disease: a systematic review.

  2011cited by this paper
• Systematic reviews: CRD's guidance for undertaking reviews in health care

  2010cited by this paper
• How to write a Cochrane systematic review

  2010cited by this paper
• Maternal and fetal outcome in women with type 2 versus type 1 diabetes mellitus: a systematic review and metaanalysis.

  2009cited by this paper
• The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies.

  2009cited by this paper
• The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration

  2009cited by this paper
• Delivering interventions to reduce the global burden of stillbirths: improving service supply and community demand

  2009cited by this paper
• Reducing stillbirths: screening and monitoring during pregnancy and labour

  2009cited by this paper
• The PRISMA Statement for Reporting Systematic Reviews and Meta-Analyses of Studies That Evaluate Health Care Interventions: Explanation and Elaboration

  2009cited by this paper
• Maternal age and risk of stillbirth: a systematic review

  2008cited by this paper
• Clinical Prediction Models

  2008cited by this paper
• Strengthening the reporting of observational studies in epidemiology (STROBE) statement: guidelines for reporting observational studies

  2007cited by this paper
• Maternal Uterine Artery Doppler Flow Velocimetry and the Risk of Stillbirth

  2007cited by this paper
• External Validation of a Measurement Tool to Assess Systematic Reviews (AMSTAR)

  2007cited by this paper
• Risk Factors for Stillbirth in Developing Countries: A Systematic Review of the Literature

  2007cited by this paper
• Systematic review of effects of low–moderate prenatal alcohol exposure on pregnancy outcome

  2007cited by this paper
• Maternal obesity and risk of stillbirth: a metaanalysis.

  2007cited by this paper
• Accuracy of serum uric acid in predicting complications of pre‐eclampsia: a systematic review

  2006cited by this paper
• Mortality in offspring of parents with psychotic disorders: a critical review and meta-analysis.

  2005cited by this paper
• Classification of stillbirth by relevant condition at death (ReCoDe): population based cohort study

  2005cited by this paper
• Systematic reviews with individual patient data meta-analysis to evaluate diagnostic tests.

  2003cited by this paper
• How strong is the association between maternal thrombophilia and adverse pregnancy outcome? A systematic review.

  2002cited by this paper
• Vaginal bleeding and adverse reproductive outcomes: a meta‐analysis

  1994cited by this paper
• Vaginal bleeding and adverse reproductive outcomes: a meta-analysis.

  1994cited by this paper

• Maternal circulating sFlt-1/placental growth factor is a biomarker of fetal death associated with placental lesions of maternal vascular malperfusion

  2026cites this paper
• Association Between Neighborhood Social Determinants of Health and Stillbirth

  2025cites this paper
• The Role of Angiogenic Factors in Fetal Growth Restriction.

  2025cites this paper
• The Application of Machine Learning Models to Predict Stillbirths

  2025cites this paper
• Mediators affecting the higher risk of stillbirth among foreign‐born women in Sweden: A nationwide cohort study

  2025cites this paper
• The relationship between maternal uterine artery doppler ultrasound during the second and third trimesters and infant cognitive development at one year of age: Findings from a South African prospective cohort study

  2025cites this paper
• Total bile acid concentrations and adverse perinatal outcomes in chinese intrahepatic cholestasis of pregnancy including asymptomatic hypercholanemia of pregnancy: a retrospective cohort study

  2025cites this paper
• Prediction of stillbirth using machine learning methods

  2025cites this paper
• Predicting the Risk of Stillbirth for Small Infants Using Maternal and Pregnancy Characteristics

  2025cites this paper
• Translation of mechanistic advances in preeclampsia to the clinic: Long and winding road

  2024cites this paper
• Prospective Community-based Study of Still Births in Remote Villages with Low Resources

  2024cites this paper
• Raportul sFlt-1/PlGF în restricţia de creştere fetală, naşterea cu făt mort şi naşterea prematură

  2024cites this paper
• Prevention of Pregnancy Complications Using a Multimodal Lifestyle, Screening, and Medical Model

  2024influential citation
• Prioritisation of early pregnancy risk factors for stillbirth: An international multistakeholder modified e-Delphi consensus study.

  2024cites this paper
• Identifying risk of stillbirth using machine learning.

  2023cites this paper
• Stillbirth risk factors, causes and evaluation.

  2023cites this paper
• Placental Pathology Findings in Unexplained Pregnancy Losses

  2023cites this paper
• Cerebroplacental ratio as an indicator of placental functioning and its relationship with early communicative gestures acquisition

  2023cites this paper
• Risk factors for late preterm and term stillbirth: A secondary analysis of an individual participant data meta‐analysis

  2023cites this paper
• Etiology of stillbirth in a tertiary care center: a retrospective cohort study assessing ultrasound, laboratory, and pathology investigations

  2023cites this paper
• External validation of prognostic models to predict stillbirth using International Prediction of Pregnancy Complications (IPPIC) Network database: individual participant data meta-analysis

  2022cites this paper
• Predicting singleton antepartum stillbirth by the demographic Fetal Medicine Foundation Risk Calculator—A retrospective case-control study

  2022influential citation
• Middle cerebral arterial flow redistribution is an indicator for intrauterine fetal compromise in late pregnancy in low‐resource settings: A prospective cohort study

  2022cites this paper
• First-trimester prediction model for placental vascular disorders: An observational prospective study.

  2022cites this paper
• Universal gestational diabetes screening and antepartum stillbirth rates in Austria—A population‐based study

  2022cites this paper
• Maternal characteristics as indications for routine induction of labor: A nationwide retrospective cohort study

  2022cites this paper
• Abnormal placental villous maturity and dysregulated glucose metabolism: implications for stillbirth prevention

  2022cites this paper
• Methodological approaches for assessing certainty of the evidence in umbrella reviews: A scoping review

  2022cites this paper
• Clinical utility of sFlt‐1 and PlGF in screening, prediction, diagnosis and monitoring of pre‐eclampsia and fetal growth restriction

  2022cites this paper
• Clinical Biochemical Indicators and Intestinal Microbiota Testing Reveal the Influence of Reproductive Age Extending from the Mother to the Offspring

  2022cites this paper
• Exploring first‐time mothers' experiences and knowledge about behavioural risk factors for stillbirth

  2022cites this paper
• Morphological and functional changes in placentas from prolonged pregnancies.

  2022cites this paper
• Parity and the risks of adverse birth outcomes: a retrospective study among Chinese

  2021cites this paper
• Social Determinants of Health and Risk of Stillbirth in the United States

  2021cites this paper
• Predictive performance for placental dysfunction related stillbirth of the competing risks model for small‐for‐gestational‐age fetuses

  2021cites this paper
• Prediction and prevention of stillbirth: dream or reality

  2021cites this paper
• External validation of prognostic models to predict stillbirth using International Prediction of Pregnancy Complications (IPPIC) Network database: individual participant data meta‐analysis

  2021cites this paper
• Management of Preeclampsia in Low- and Middle-Income Countries: Lessons to Date, and Questions Arising, from the PRE-EMPT and Related Initiatives

  2021cites this paper