Solution thermodynamic stability of complexes formed with the octadentate hydroxypyridinonate ligand 3,4,3-LI(1,2-HOPO): a critical feature for efficient chelation of lanthanide(IV) and actinide(IV) ions.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Inorganic Chemistry

• Publication date

  2013-07-16

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1021/ic4010246PMID 23855806PMCID PMC3771511
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Solution thermodynamic stability of complexes formed with the octadentate hydroxypyridinonate ligand 3,4,3-LI(1,2-HOPO): a critical feature for efficient chelation of lanthanide(IV) and actinide(IV) ions.

  2013cited by this paper
• Solution thermodynamic evaluation of hydroxypyridinonate chelators 3,4,3-LI(1,2-HOPO) and 5-LIO(Me-3,2-HOPO) for UO2(VI) and Th(IV) decorporation

  2013cited by this paper
• Aqueous complexation of thorium(IV), uranium(IV), neptunium(IV), plutonium(III/IV), and cerium(III/IV) with DTPA.

  2012cited by this paper
• 3,4,3-LI(1,2-HOPO): in vitro formation of highly stable lanthanide complexes translates into efficacious in vivo europium decorporation.

  2011cited by this paper
• Biomimetic actinide chelators: an update on the preclinical development of the orally active hydroxypyridonate decorporation agents 3,4,3-LI(1,2-HOPO) and 5-LIO(Me-3,2-HOPO).

  2010cited by this paper
• Redox behavior of Ce(IV)/Ce(III) in the presence of nitrilotriacetic acid: A surrogate study for An(IV)/An(III) redox behavior

  2010cited by this paper
• Using the antenna effect as a spectroscopic tool: photophysics and solution thermodynamics of the model luminescent hydroxypyridonate complex [Eu(III)(3,4,3-LI(1,2-HOPO))]-.

  2009cited by this paper
• LAURISTON S. TAYLOR LECTURE: THE QUEST FOR THERAPEUTIC ACTINIDE CHELATORS

  2008cited by this paper
• Characterisation of thorium-ethylenediaminetetraacetic acid and thorium-nitrilotriacetic acid species by electrospray ionisation-mass spectrometry.

  2007cited by this paper
• Critical evaluation of stability constants of metal complexes of complexones for biomedical and environmental applications* (IUPAC Technical Report)

  2005cited by this paper
• GLEE, a new computer program for glass electrode calibration.

  2000cited by this paper
• Hyperquad simulation and speciation (HySS): a utility program for the investigation of equilibria involving soluble and partially soluble species

  1999cited by this paper
• Recent Developments in the Decorporation of Plutonium, Americium and Thorium

  1998cited by this paper
• Investigation of equilibria in solution. Determination of equilibrium constants with the HYPERQUAD suite of programs.

  1996cited by this paper
• Specific sequestering agents for the actinides. 28. Synthesis and initial evaluation of multidentate 4-carbamoyl-3-hydroxyl-1-methyl-2(1H)-pyridinone ligands for in vivo plutonium(IV) chelation.

  1995cited by this paper
• Specific sequestering agents for the actinides. 16. Synthesis and initial biological testing of polydentate oxohydroxypyridinecarboxylate ligands.

  1988cited by this paper
• Revised effective ionic radii and systematic studies of interatomic distances in halides and chalcogenides

  1976cited by this paper
• PRESENT STATUS OF CERIUM(IV)-CERIUM(III) POTENTIALS

  1957cited by this paper
• International Union of Pure and Applied Chemistry a Critical Evaluation of the Redox Properties of Uranium, Neptunium and Plutonium Ions in Acidic Aqueous Solutions

  year unknowncited by this paper

• Synthesis and evaluation of HOPO-O8-Methyl-tetrazine as a bifunctional chelator for use in [89Zr]Zr4+, [161Tb]Tb3+ and [227Th]Th4+ radioimmunoconjugates.

  2025cites this paper
• Chelating [227Th]Th4+ for Peptide Receptor Radionuclide Therapy of Neuroendocrine Tumors.

  2025cites this paper
• A Comprehensive Machine Learning Model for Metal–Ligand Binding Prediction: Applications in Chemistry and Biology

  2025cites this paper
• Gold Nanoparticle-Enabled Fluorescence Sensing of Gadolinium-Based Contrast Agents in Urine

  2025cites this paper
• Siderocalin fusion proteins enable a new 86Y/90Y theranostic approach

  2023cites this paper
• Investigation of Chelating Agents for the Removal of Thorium from Human Teeth upon Nuclear Contamination.

  2023cites this paper
• Electron paramagnetic resonance, electronic ground state, and electron spin relaxation of seven lanthanide ions bound to lanmodulin and the bioinspired chelator, 3,4,3-LI(1,2-HOPO).

  2023cites this paper
• Macrocyclic 1,2-Hydroxypyridinone-Based Chelators as Potential Ligands for Thorium-227 and Zirconium-89 Radiopharmaceuticals.

  2023cites this paper
• Theoretical Investigation of Actinide Ligation in Aqueous and Organic Phase for Nuclear Waste Treatment.

  2023cites this paper
• Hydrophilic Chelators for Aqueous Reprocessing of Spent Nuclear Fuel

  2023cites this paper
• Chelation Behaviors of 3,4,3-LI(1,2-HOPO) with Lanthanides and Actinides Implicated by Molecular Dynamics Simulations.

  2023cites this paper
• Comparative Study of a Decadentate Acyclic Chelate, HOPO-O10, and Its Octadentate Analogue, HOPO-O8, for Radiopharmaceutical Applications.

  2023cites this paper
• Precision Engineering of 2D Protein Layers as Chelating Biogenic Scaffolds for Selective Recovery of Rare-Earth Elements.

  2022cites this paper
• Hydroxypyridinone-Based Metal Chelators towards Ecotoxicity: Remediation and Biological Mechanisms

  2022cites this paper
• DOTP versus DOTA as ligands for lanthanide cations: Novel structurally characterized Ce(IV) and Ce(III) cyclen-based complexes and clusters in aqueous solutions.

  2022cites this paper
• In situ beam reduction of Pu(IV) and Bk(IV) as a route to trivalent transuranic coordination complexes with hydroxypyridinone chelators

  2022cites this paper
• Overview of the Most Promising Radionuclides for Targeted Alpha Therapy: The “Hopeful Eight”

  2021cites this paper
• Combining the Best of Two Chelating Titans: A Hydroxypyridinone-Decorated Macrocyclic Ligand for Efficient and Concomitant Complexation and Sensitized Luminescence of f-Elements.

  2021cites this paper
• Characterization of Thorium-Pyrazinoic acid complexation and its decorporation efficacy in human cells and blood.

  2021cites this paper
• to Complexes in

  2021cites this paper
• Hydroxypyridinones as a Very Promising Platform for Targeted Diagnostic and Therapeutic Radiopharmaceuticals

  2021cites this paper
• [nat/89Zr][Zr(pypa)]: Thermodynamically Stable and Kinetically Inert Binary Nonadentate Complex for Radiopharmaceutical Applications.

  2021cites this paper
• Chelator-assisted high performance liquid chromatographic separation of trivalent lanthanides and actinides

  2021cites this paper
• Thermodynamic Stability and Speciation of Ga(III) and Zr(IV) Complexes with High-Denticity Hydroxamate Chelators

  2021cites this paper
• DGA resin capacity factors for Ac, Am and Th under tetravalent actinide selective complexation

  2021cites this paper
• Spectrophotometric methods to probe the solution chemistry of lanthanide complexes with macromolecules.

  2021cites this paper
• Controlling the Reduction of Chelated Uranyl to Stable Tetravalent Uranium Coordination Complexes in Aqueous Solution.

  2020cites this paper
• Developing scandium and yttrium coordination chemistry to advance theranostic radiopharmaceuticals

  2020cites this paper
• The chemical and physical properties of tetravalent lanthanides: Pr, Nd, Tb, and Dy.

  2020cites this paper
• Hydroxypyridinone Derivatives: A Low-pH Alternative to Polyaminocarboxylates for TALSPEAK-like Separation of Trivalent Actinides from Lanthanides

  2020cites this paper
• Polyoxometalate-based complexes as ligands for the study of actinide chemistry.

  2020cites this paper
• Developing the 134Ce and 134La pair as companion positron emission tomography diagnostic isotopes for 225Ac and 227Th radiotherapeutics

  2020cites this paper
• Hydroxypyridinone-based stabilization of Np(IV) enabling efficient U/Np/Pu separations in the Adapted PUREX process

  2020cites this paper
• Spontaneous, Chelation-Driven Reduction of the Neptunyl Cation in Aqueous Solution.

  2020cites this paper
• Selective Lanthanide Sensing with Gold Nanoparticles and Hydroxypyridinone Chelators.

  2020cites this paper
• Periodic trends and complexation chemistry of tetravalent actinide ions with a potential actinide decorporation agent 5‐LIO(Me‐3,2‐HOPO): A relativistic density functional theory exploration

  2020cites this paper
• Mobilization and partitioning of rare earth elements in the presence of humic acids and siderophores.

  2020cites this paper
• Rapid Detection of Gadolinium-Based Contrast Agents in Urine with a Chelated Europium Luminescent Probe.

  2020cites this paper
• Inducing selectivity and chirality in group IV metal coordination with high-denticity hydroxypyridinones.

  2019cites this paper
• Is hydroxypyridonate 3,4,3-LI(1,2-HOPO) a good competitor of fetuin for uranyl metabolism?

  2019cites this paper
• Contemporary Chemistry of Berkelium and Californium.

  2019cites this paper
• Ultra-selective ligand-driven separation of strategic actinides

  2019cites this paper
• The solution thermodynamic stability of desferrioxamine B (DFO) with Zr(IV).

  2019cites this paper
• Carboxylate- and Phosphonate-Modified Polyethylenimine: Toward the Design of Actinide Decorporation Agents.

  2019cites this paper
• Bond Covalency and Oxidation State of Actinide Ions Complexed with Therapeutic Chelating Agent 3,4,3-LI(1,2-HOPO).

  2018cites this paper
• Toxic heavy metal – Pb, Cd, Sn – complexation by the octadentate hydroxypyridinonate ligand archetype 3,4,3-LI(1,2-HOPO)

  2018cites this paper
• Works Title Bond Covalency and Oxidation State of Actinide Ions Complexed with Therapeutic Chelating Agent

  2018cites this paper
• The coordination chemistry of lanthanide and actinide metal ions with hydroxypyridinone-based decorporation agents: orbital and density based analyses.

  2018cites this paper
• Solution Thermodynamics and Kinetics of Metal Complexation with a Hydroxypyridinone Chelator Designed for Thorium-227 Targeted Alpha Therapy.

  2018cites this paper
• Reductive activation of neptunyl and plutonyl oxo species with a hydroxypyridinone chelating ligand.

  2018cites this paper
• Octadentate chelators for zirconium- and other metal-based radiopharmaceuticals

  2018cites this paper
• Chelation and stabilization of berkelium in oxidation state +IV.

  2017cites this paper
• Structural and thermodynamic investigation of AnIVLI(O)HOPO

  2017cites this paper
• Mécanisme d'interaction des actinides avec une proteine : la calmoduline.

  2016cites this paper
• Title Engineered recognition of tetravalent zirconium and thorium by chelator-protein systems : Toward flexible radiotherapy and imaging platforms Permalink

  2016cites this paper
• A Macrocyclic Chelator That Selectively Binds Ln4+ over Ln3+ by a Factor of 1029.

  2016cites this paper
• Ligand-Sensitized Lanthanide Nanocrystals: Merging Solid-State Photophysics and Molecular Solution Chemistry.

  2016cites this paper
• Engineered Recognition of Tetravalent Zirconium and Thorium by Chelator-Protein Systems: Toward Flexible Radiotherapy and Imaging Platforms.

  2016cites this paper
• An efficient chelator for complexation of thorium-227.

  2016cites this paper
• The interaction of human serum albumin with selected lanthanide and actinide ions: Binding affinities, protein unfolding and conformational changes.

  2016cites this paper
• Spectroscopic, electrochemical, and structural aspects of the Ce(IV)/Ce(III) DOTA redox couple chemistry in aqueous solutions

  2016cites this paper
• New Insights into Structure and Luminescence of EuIII and SmIII Complexes of the 3,4,3-LI(1,2-HOPO) Ligand

  2015cites this paper
• Characterization, HPLC method development and impurity identification for 3,4,3-LI(1,2-HOPO), a potent actinide chelator for radionuclide decorporation.

  2015cites this paper
• Experimental and computational exploration of the UV-visible properties of hexaniobate and hexatantalate ions

  2015cites this paper
• Zirconium-89: Radiochemistry and Ligand Development toward Improved PET Applications

  2015cites this paper
• Recovery of yttrium and lanthanides from sulfate solutions with high concentration of iron and low rare earth content

  2015cites this paper
• Hydroxypyridinonate complex stability of group (IV) metals and tetravalent f-block elements: the key to the next generation of chelating agents for radiopharmaceuticals.

  2015cites this paper
• A 4-tert-butylcalix[4]arene tetrahydroxamate podand based on the 1-oxypiperidine-2-one (1,2-PIPO−) chelate. Self-assembly into a supramolecular ionophore driven by coordination of tetravalent zirconium or hafnium(IV)

  2014cites this paper
• C2E2.: An orally administered radionuclide decorporation adent

  2014cites this paper
• Highly luminescent and stable hydroxypyridinonate complexes: a step towards new curium decontamination strategies.

  2014cites this paper
• The electrochemical behavior of cerium(III/IV) complexes: Thermodynamics, kinetics and applications in synthesis

  2014cites this paper
• Alternative Chelator for 89Zr Radiopharmaceuticals: Radiolabeling and Evaluation of 3,4,3-(LI-1,2-HOPO)

  2014cites this paper
• Solution thermodynamic stability of complexes formed with the octadentate hydroxypyridinonate ligand 3,4,3-LI(1,2-HOPO): a critical feature for efficient chelation of lanthanide(IV) and actinide(IV) ions.

  2013cites this paper
• Hydrophilic chelators for coordination and separation of radioactive f-block elements

  year unknowncites this paper