Plasma kinetics in man of epicatechin from black chocolate

No abstract is available for this paper.

• Publication year

  1999

• Venue

  European Journal of Clinical Nutrition

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  DOI 10.1038/sj.ejcn.1600673PMID 10048796
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Bioactive ingredients: antioxidants and polyphenols in tea.

  2009cited by this paper
• THE MECHANISM OF CACAO CURING.

  2006cited by this paper
• Simple high-performance liquid chromatography method for the simultaneous determination of serum caffeine and paraxanthine following rapid sample preparation.

  1998cited by this paper
• Dose-dependent incorporation of tea catechins, (-)-epigallocatechin-3-gallate and (-)-epigallocatechin, into human plasma.

  1997influential reference
• Absorption, metabolism and health effects of dietary flavonoids in man.

  1997cited by this paper
• Inhibition of LDL oxidation by cocoa.

  1996cited by this paper
• In vivo antioxidant effect of green and black tea in man.

  1996cited by this paper
• Antioxidants in chocolate.

  1996cited by this paper
• Inhibition of LDL oxidation by cocoa

  1996cited by this paper
• Structure-antioxidant activity relationships of flavonoids and phenolic acids.

  1996cited by this paper
• Flavonoids—Chemistry, metabolism, cardioprotective effects, and dietary sources

  1996cited by this paper
• Analysis of plasma and urinary tea polyphenols in human subjects.

  1995cited by this paper
• Determination of (+)-catechin in plasma by high-performance liquid chromatography using fluorescence detection.

  1995cited by this paper
• Clinical pharmacokinetics: Concepts and applications (2nd edn.)

  1989cited by this paper
• Clinical pharmacokinetics : concepts and applications

  1989cited by this paper
• Epicatechin Content in Fermented and Unfermented Cocoa Beans

  1984cited by this paper
• Applied biopharmaceutics and pharmacokinetics

  1980cited by this paper
• Studies on flavonoid metabolism. Metabolism of (+)-[14C] catechin in the rat and guinea pig.

  1969cited by this paper
• Phenolic acids and flavonoids of Theobroma cacao L.; separation and identification by paper chromatography.

  1958cited by this paper
• Fermentation, Drying, and Storage of Cacao Beans

  1958cited by this paper
• Cacao polyphenolic substances. 4. The anthocyanin pigments.

  1957cited by this paper
• Cacao polyphenolic substances. 3. Separation and estimation on paper chromatograms.

  1955cited by this paper

• Bioavailable Microbial Metabolites of Flavanols Demonstrate Highly Individualized Bioactivity on In Vitro β-Cell Functions Critical for Metabolic Health

  2023cites this paper
• Dark chocolate: An overview of its biological activity, processing, and fortification approaches

  2022cites this paper
• Cyrcadian Rhythm, Mood, and Temporal Patterns of Eating Chocolate: A Scoping Review of Physiology, Findings, and Future Directions

  2022cites this paper
• Muscle Support Supplement by APOC, Medical Food EP1 (Cacao Advanced®): Systematic Review and Meta-Analysis Exploring the Supplement’s Main Ingredient, the Cacao Flavanol l-Epicatechin and its Relationship Between the Follistatin to Myostatin Ratio

  2022cites this paper
• Cocoa and chocolate consumption and prevention of cardiovascular diseases and other chronic diseases

  2022cites this paper
• Evaluation of blood pressure lowering effects of cocoa flavanols in diabetes mellitus: A systematic review and meta-analysis

  2021cites this paper
• (-)-Epicatechin acts as a potent agonist of the membrane androgen receptor, ZIP9 (SLC39A9), to promote apoptosis of breast and prostate cancer cells.

  2021cites this paper
• Possible Antioxidant and Haematinic Properties of the Stem Bark of Theobroma cacao L. in Wistar Rats

  2021cites this paper
• Improvement of the Flavanol Profile and the Antioxidant Capacity of Chocolate Using a Phenolic Rich Cocoa Powder

  2020cites this paper
• Low Plasma Appearance of (+)-Catechin and (−)-Catechin Compared with Epicatechin after Consumption of Beverages Prepared from Nonalkalized or Alkalized Cocoa—A Randomized, Double-Blind Trial

  2020cites this paper
• Pine bark phenolic extract: current uses and potential food applications.

  2020cites this paper
• Keracunan Coklat (Theobroma Cacao) pada Anjing: Manajemen Terapi dan Pencegahan

  2020cites this paper
• Effects of (-)-epicatechin on mitochondria.

  2020cites this paper
• Bioavailability and metabolism of selected cocoa bioactive compounds: A comprehensive review

  2020cites this paper
• Biological functions of epicatechin: Plant cell to human cell health

  2019cites this paper
• Impact of Cocoa Products Intake on Plasma and Urine Metabolites: A Review of Targeted and Non-Targeted Studies in Humans

  2019cites this paper
• Fast reaction of carbon free radicals with flavonoids and other aromatic compounds.

  2019cites this paper
• Cocoa Consumption and Prevention of Cardiometabolic Diseases and Other Chronic Diseases

  2019cites this paper
• Impact de la fermentation sur les propriétés antioxydantes, anti-inflammatoires et immunomodulatrices du cacao

  2019cites this paper
• The Effect of a Single Dose of Dark Chocolate on Cardiovascular Parameters and Their Reactivity to Mental Stress

  2019cites this paper
• Flavanol Bioavailability in Two Cocoa Products with Different Phenolic Content. A Comparative Study in Humans

  2019cites this paper
• (−)‐Epicatechin‐induced relaxation of isolated human saphenous vein: Roles of K+ and Ca2+ channels

  2018cites this paper
• Use of LC‐MS for the quantitative analysis of (poly)phenol metabolites does not necessarily yield accurate results: Implications for assessing existing data and conducting future research

  2018cites this paper
• Effect of High Antioxidant Cacao Consumption on Behaviors in Children with Autism Spectrum Disorder

  2018cites this paper
• The Bioavailability, Transport, and Bioactivity of Dietary Flavonoids: A Review from a Historical Perspective.

  2018cites this paper
• The influence of chocolate on human health

  2018cites this paper
• Biological activities of (-)-epicatechin and (-)-epicatechin-containing foods: Focus on cardiovascular and neuropsychological health.

  2018cites this paper
• Biomarkers of food intake for cocoa and liquorice (products): a systematic review

  2018cites this paper
• Influence of drying methods on cocoa (Theobroma cacao L.): antioxidant activity and presence of ochratoxin A

  2018cites this paper
• 5-(3′,4′-Dihydroxyphenyl-γ-valerolactone), a Major Microbial Metabolite of Proanthocyanidin, Attenuates THP-1 Monocyte-Endothelial Adhesion

  2017cites this paper
• EVALUATION OF YAK-KONG SOYBEAN (GLYCINE MAX) FOR ITS PHENOLICS AND METABOLITES WITH A FOCUS ON ATHEROSCLEROSIS PREVENTION

  2017influential citation
• Absorption, metabolism, distribution and excretion of (-)-epicatechin: A review of recent findings.

  2017cites this paper
• EFFECTS OF ALKALIZATION AND ROASTING ON FREE AND BOUND PHENOLIC COMPOUNDS IN COCOA NIBS AND SHELLS

  2017cites this paper
• The Effect and Acceptability of Increased Whole Apple Consumption, Apple Extract and Freeze-Dried Apple Pieces on Biomarkers of CVD Risk: The APPS Pilot Study

  2017cites this paper
• Enhancing Human Cognition with Cocoa Flavonoids

  2017cites this paper
• Cocoa, Blood Pressure, and Vascular Function

  2017cites this paper
• (-)-Epicatechin-induced recovery of mitochondria from simulated diabetes: Potential role of endothelial nitric oxide synthase

  2016cites this paper
• Acute cocoa flavanol supplementation improves muscle macro- and microvascular but not anabolic responses to amino acids in older men.

  2016cites this paper
• Determination of antioxidant capacity and phenolic content of chocolate by attenuated total reflectance-Fourier transformed-infrared spectroscopy.

  2016cites this paper
• Foods, Nutrients and Food Ingredients with Authorised EU Health Claims : Volume 3

  2016cites this paper
• Cocoa extract intake for 4 weeks reduces postprandial systolic blood pressure response of obese subjects, even after following an energy-restricted diet

  2016cites this paper
• Change in stability of procyanidins, antioxidant capacity and in-vitro bioaccessibility during processing of cocoa powder from cocoa beans

  2016cites this paper
• Impact of Cocoa Consumption on Inflammation Processes—A Critical Review of Randomized Controlled Trials

  2016cites this paper
• Bioactive compounds in different cocoa (Theobroma cacao, L) cultivars during fermentation

  2015cites this paper
• Authorised EU health claim for cocoa flavanols

  2015cites this paper
• Czekolada jako źródło związków bioaktywnych oddziałujących na organizm = Chocolate as a source of bioactive compounds acting on the organism

  2015cites this paper
• Prescripción de ejercicio físico en la prevención y tratamiento de la hipertensión arterial. Documento de Consenso de la Sociedad Española de Medicina del Deporte (SEMED-FEMEDE)

  2015cites this paper
• Association of flavonoid-rich foods and statins in the management of hypercholesterolemia: a dangerous or helpful combination?

  2015cites this paper
• Comparative biokinetics and metabolism of pure monomeric, dimeric, and polymeric flavan-3-ols: a randomized cross-over study in humans.

  2015cites this paper
• Chemoprevention of Breast Cancer by Dietary Polyphenols

  2015cites this paper
• Chocolate and other cocoa products: effects on human reproduction and pregnancy.

  2015cites this paper
• Factors Affecting the Absorption, Metabolism, and Excretion of Cocoa Flavanols in Humans.

  2015cites this paper
• The blood pressure effect and related plasma levels of flavan-3-ols in spontaneously hypertensive rats.

  2015cites this paper
• Brain Protection and Cognitive Function: Cocoa Flavonoids as Nutraceuticals.

  2015cites this paper
• Effect of cocoa products and flavanols on platelet aggregation in humans: a systematic review.

  2015cites this paper
• Improving the estimation of flavonoid intake for study of health outcomes.

  2015cites this paper
• Plant Secondary Metabolites: Occurrence, Structure And Role In The Human Diet

  2014cites this paper
• Chapter 44 - The Impact of Gastrointestinal Modifications, Blood-Brain Barrier Transport, and Intracellular Metabolism on Polyphenol Bioavailability: An Overview

  2014cites this paper
• The effect of acute dark chocolate consumption on carbohydrate metabolism and performance during rest and exercise.

  2014cites this paper
• Female fetuses are more reactive when mother eats chocolate

  2014cites this paper
• Intravenous (-)-epicatechin reduces myocardial ischemic injury by protecting mitochondrial function.

  2014cites this paper
• Effects of dark chocolate consumption on the prothrombotic response to acute psychosocial stress in healthy men

  2014cites this paper
• Cocoa Polyphenols and Inflammatory Markers of Cardiovascular Disease

  2014cites this paper
• Flavonoids as regulators of amyloid precursor protein processing

  2014cites this paper
• Cocoa flavanols and cardioprotective effects Which flavanols may contribute to cardiovascular health

  2014cites this paper
• Consumption of both low and high (-)-epicatechin apple puree attenuates platelet reactivity and increases plasma concentrations of nitric oxide metabolites: a randomized controlled trial.

  2014cites this paper
• Effect of food matrix interaction between dietary fibre and polyphenols on their metabolism by colonic bacteria

  2014cites this paper
• Cocoa Phytochemicals: Recent Advances in Molecular Mechanisms on Health

  2014cites this paper
• Impact of dietary and microbial fatty acids on the bioavailability of phenolics

  2014cites this paper
• Chocolate flavanols and skin photoprotection: a parallel, double-blind, randomized clinical trial

  2014cites this paper
• Chocolate and the brain: neurobiological impact of cocoa flavanols on cognition and behavior.

  2013cites this paper
• Blood pressure and endothelial function in healthy, pregnant women after acute and daily consumption of flavanol-rich chocolate: a pilot, randomized controlled trial

  2013influential citation
• Proanthocyanidins of Cocoa: Bioavailability and Biological Activities 74

  2013cites this paper
• The neuroprotective effects of cocoa flavanol and its influence on cognitive performance.

  2013cites this paper
• The Absorption, Metabolism, and Pharmacokinetics of Chocolate Polyphenols

  2013cites this paper
• Cocoa, Blood Flow and the Brain

  2013cites this paper
• Polyphenol-rich dark chocolate in treatment of diabetes mellitus risk factors

  2013cites this paper
• Bioavailability of epicatechin and effects on nitric oxide metabolites of an apple flavanol-rich extract supplemented beverage compared to a whole apple puree: a randomized, placebo-controlled, crossover trial.

  2013cites this paper
• Dietary (Poly)phenolics in Human Health: Structures, Bioavailability, and Evidence of Protective Effects Against Chronic Diseases

  2013influential citation
• Phenolic compounds, methylxanthines and antioxidant activity in cocoa mass and chocolates produced from "witch broom disease" resistant and non resistant cocoa cultivars

  2013cites this paper
• Cardioprotective effects of cocoa: clinical evidence from randomized clinical intervention trials in humans.

  2013cites this paper
• Endothelium/nitric oxide mechanism mediates vasorelaxation and counteracts vasoconstriction induced by low concentration of flavanols

  2013cites this paper
• Bioavailability of bioactive food compounds: a challenging journey to bioefficacy.

  2013cites this paper
• Analysis of phytochemical in a Malaysian medicinal plant and the bioavailability of dietary hydroxycinnamates

  2013cites this paper
• Effects of (-)-epicatechin and derivatives on nitric oxide mediated induction of mitochondrial proteins.

  2013cites this paper
• Polyphenols in Cocoa: From In Vitro Digestion to In Vivo Bioavailability

  2013cites this paper
• Bioavailability of dietary monomeric and polymeric flavan-3-ols

  2012cites this paper
• Human bioavailability of flavanols and phenolic acids from cocoa-nut creams enriched with free or microencapsulated cocoa polyphenols

  2012cites this paper
• Effets de la consommation de chocolat sur la fonction endothéliale et la tension artérielle des femmes enceintes : une étude pilote

  2012cites this paper
• Influence of sugar type on the bioavailability of cocoa flavanols

  2012cites this paper
• Chapter 6 – Antioxidants in biology

  2012cites this paper
• EVALUACION DEL EFECTO DEL PROCESAMIENTO DEL CACAO SOBRE EL CONTENIDO DE POLIFENOLES Y SU ACTIVIDAD ANTIOXIDANTE

  2012cites this paper
• Phytochemical Intakes with a Mediterranean Diet: Levels Achievable with an Exchange List Diet and Potential Biomarkers in Blood

  2012cites this paper
• The effect of oligomeric procyanidins on endothelial function and cholesterol homeostasis

  2012cites this paper
• Cocoa, Blood Pressure, and Vascular Function

  2012cites this paper
• Human O-sulfated metabolites of (-)-epicatechin and methyl-(-)-epicatechin are poor substrates for commercial aryl-sulfatases: implications for studies concerned with quantifying epicatechin bioavailability.

  2012cites this paper
• Polyphenol metabolism: from in vitro to in vivo approaches

  2012cites this paper
• Vascular and Platelet Effects of Cocoa

  2012cites this paper
• POTENCIALIDADES Y SISTEMAS DE COMERCIALIZACIÓN PARA LOS PRODUCTOS AGROPRODUCTIVOS Y AGROFORESTALES DE LA MICROCUENCA MEMBRILLO

  2012cites this paper
• Elucidation of (-)-epicatechin metabolites after ingestion of chocolate by healthy humans.

  2012cites this paper