A new bacteriophage P1–derived vector for the propagation of large human DNA fragments

No abstract is available for this paper.

• Publication year

  1994

• Venue

  Nature Genetics

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/NG0194-84PMID 8136839
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• A mouse genomic library in the bacteriophage P1 cloning system: organization and characterization

  2004cited by this paper
• PCR probes for chromosome in situ hybridization of large-insert bacterial recombinants.

  1994cited by this paper
• Automated production of high density cosmid and YAC colony filters using a robotic workstation.

  1993cited by this paper
• A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic mice

  1993cited by this paper
• Germ line transmission of a yeast artificial chromosome spanning the murine alpha 1(I) collagen locus.

  1993cited by this paper
• Fluorescence in situ hybridization mapping of human chromosome 19: cytogenetic band location of 540 cosmids and 70 genes or DNA markers.

  1993cited by this paper
• The human Y chromosome: overlapping DNA clones spanning the euchromatic region.

  1992cited by this paper
• The selective isolation of novel cDNAs encoded by the regions surrounding the human interleukin 4 and 5 genes.

  1992cited by this paper
• Cloning of the essential myotonic dystrophy region and mapping of the putative defect

  1992cited by this paper
• Continuum of overlapping clones spanning the entire human chromosome 21q

  1992cited by this paper
• The CEPH YAC library.

  1992cited by this paper
• Construction of a mouse yeast artificial chromosome library in a recombination–deficient strain of yeast

  1992cited by this paper
• Chromosomal assignment of human YAC clones by fluorescence in situ hybridization: use of single-yeast-colony PCR and multiple labeling.

  1992cited by this paper
• Characterization of a yeast artificial chromosome contig spanning the Huntington's disease gene candidate region

  1992cited by this paper
• Stable propagation of cosmid sized human DNA inserts in an F factor based vector.

  1992cited by this paper
• Mapping the whole human genome by fingerprinting yeast artificial chromosomes.

  1992cited by this paper
• Cloning and stable maintenance of 300-kilobase-pair fragments of human DNA in Escherichia coli using an F-factor-based vector.

  1992cited by this paper
• A positive selection vector for cloning high molecular weight DNA by the bacteriophage P1 system: improved cloning efficacy.

  1992cited by this paper
• Complete coverage of the Schizosaccharomyces pombe genome in yeast artificial chromosomes

  1992cited by this paper
• Nonrandom F-plasmid replication in Escherichia coli K-12

  1992cited by this paper
• A phage T4 in vitro packaging system for cloning long DNA molecules.

  1992cited by this paper
• cDNA selection: efficient PCR approach for the selection of cDNAs encoded in large chromosomal DNA fragments.

  1991cited by this paper
• Plasmid transformation of Escherichia coli and other bacteria.

  1991cited by this paper
• Preparation of clone libraries in yeast artificial-chromosome vectors.

  1991cited by this paper
• Construction, arraying, and high-density screening of large insert libraries of human chromosomes X and 21: their potential use as reference libraries.

  1991cited by this paper
• Exon amplification: a strategy to isolate mammalian genes based on RNA splicing.

  1991cited by this paper
• Detection and characterization of chimeric yeast artificial-chromosome clones.

  1991cited by this paper
• Rescue of unstable cosmids by in vitro packaging.

  1991cited by this paper
• Yeast artificial chromosome libraries containing large inserts from mouse and human DNA.

  1991cited by this paper
• Yeast artificial chromosome-based genome mapping: some lessons from Xq24-q28.

  1991cited by this paper
• An F factor based cloning system for large DNA fragments

  1990cited by this paper
• Differential plasmid rescue from transgenic mouse DNAs into Escherichia coli methylation-restriction mutants.

  1990cited by this paper
• Structural instability of human tandemly repeated DNA sequences cloned in yeast artificial chromosome vectors.

  1990cited by this paper
• Generation of a 50,000-member human DNA library with an average DNA insert size of 75-100 kbp in a bacteriophage P1 cloning vector.

  1990cited by this paper
• Yeast artificial chromosomes: an alternative approach to the molecular analysis of mouse developmental mutations.

  1990cited by this paper
• Ordering of cosmid clones covering the herpes simplex virus type I (HSV-I) genome: a test case for fingerprinting by hybridisation.

  1990cited by this paper
• Exon trapping: a genetic screen to identify candidate transcribed sequences in cloned mammalian genomic DNA.

  1990cited by this paper
• A New Vector for Cloning Large Eukaryotic DNA Segments in Escherichia coli

  1990cited by this paper
• Physical mapping of human chromosomes by repetitive sequence fingerprinting.

  1990cited by this paper
• A cosmid clone map derived from a small region of human chromosome 11.

  1989cited by this paper
• Human chromosome-specific DNA libraries: construction and purity analysis.

  1989cited by this paper
• Effect of the antiandrogen flutamide on pituitary LH content and release.

  1989cited by this paper
• Cloning of large segments of exogenous DNA into yeast by means of artificial chromosome vectors.

  1987cited by this paper
• Modification of the anticodon triplet of E.coli tRNAMetf by replacement with trimers complementary to non-sense codons UAG and UAA.

  1983cited by this paper
• A rapid alkaline extraction procedure for screening recombinant plasmid DNA.

  1979cited by this paper
• Cosmids: a type of plasmid gene-cloning vector that is packageable in vitro in bacteriophage lambda heads.

  1978cited by this paper

• Memories of the Human Genome Project at the Sanger Centre.

  2025cites this paper
• Overcoming challenges associated with broad sharing of human genomic data

  2025cites this paper
• Chromosome Engineering: Technologies, Applications, and Challenges.

  2024cites this paper
• A novel in-situ-process technique constructs whole circular cpDNA library

  2024cites this paper
• ASIS-Seq: Transgene Insertion Site Mapping by Nanopore Adaptive Sampling.

  2023cites this paper
• Phenotypic features of dystrophin gene knockout pigs harboring a human artificial chromosome containing the entire dystrophin gene

  2023cites this paper
• Recent Advances in Strategies for the Cloning of Natural Product Biosynthetic Gene Clusters

  2021cites this paper
• From gene to genomics

  2021cites this paper
• Therapeutic Proteins: Production and Delivery

  2021cites this paper
• Globally Important Wheat Diseases: Status, Challenges, Breeding and Genomic Tools to Enhance Resistance Durability

  2021cites this paper
• Methods for the Manipulation of Herpesvirus Genome and the Application to Marek’s Disease Virus Research

  2021cites this paper
• General Strategies for Biosynthetic Gene Cluster Identification, Capture, and Heterologous Expression

  2020cites this paper
• Molekulare Struktur und Regulation prokaryotischer Gene

  2020cites this paper
• Working with Bacterial Artificial Chromosomes (BACs) and Other High-Capacity Vectors.

  2020cites this paper
• Isolation of Full Size BAC Inserts by DNA Gap Repair in E. coli

  2019cites this paper
• Genome Engineering and Modification Toward Synthetic Biology for the Production of Antibiotics

  2018cites this paper
• Determining gene copy number in transfected caprine fibroblast cells

  2018cites this paper
• Enzymes and Cloning Vectors Used to Create Recombinant DNA, Characteristics of

  2018cites this paper
• Genetic variation in a complex polyploid: unveiling the dynamic allelic features of sugarcane

  2018cites this paper
• Large inserts for big data: artificial chromosomes in the genomic era.

  2018cites this paper
• Development of a conditionally-attenuated cytomegalovirus (CMV) vaccine vector platform, and initial investigations into use of CMV as a vaccine against pandemic influenza A virus

  2017cites this paper
• Study and exploitation of diverse soil environments for novel natural product discovery using metagenomic approaches

  2017cites this paper
• Retrofitting the BAC cloning vector pBeloBAC11 by the insertion of a mutant loxP site

  2017cites this paper
• Artificial Chromosome Constructions And Its Uses

  2017cites this paper
• Bioprospecting Soil Metagenomes for Antibiotics

  2017cites this paper
• iBAC Technologies for Neurological Disease

  2016cites this paper
• Fundamentals of Physical Mapping

  2016cites this paper
• Coevolution, Bacterial-Phage

  2016cites this paper
• Metagenomics and Metatranscriptomics for the Exploration of Natural Products from Soil Fungi

  2015cites this paper
• Generation of knockout alleles by RFLP based BAC targeting of polymorphic embryonic stem cells.

  2015cites this paper
• High Performance DNA Probes for Perinatal Detection of Numerical Chromosome Aberrations

  2015cites this paper
• Beyond Gene Inactivation: Evolution of Tools for Analysis of Serotonergic Circuitry.

  2015cites this paper
• BioBrick vectors from BioBrick parts

  2015cites this paper
• PHYSICAL MAPPING OF GENOME AND GENES

  2014cites this paper
• Towards map-based cloning of partial resistance QTLs of barley to Puccinia hordei

  2014cites this paper
• The Isolation and Characterization of TiroTheta9, a Novel A4 Mycobacterium Phage

  2014cites this paper
• Characteristics of Enzymes and Cloning Vectors Used to Create Recombinant DNA

  2014cites this paper
• Preparation of high molecular weight gDNA and bacterial artificial chromosome (BAC) libraries in plants.

  2014cites this paper
• Isolation of rare recombinants without using selectable markers for one-step seamless BAC mutagenesis

  2014cites this paper
• Genetic regulation of immunoglobulin E level in different pathological states: integration of mouse and human genetics

  2014cites this paper
• Generation of transgenic mice with megabase-sized human yeast artificial chromosomes by yeast spheroplast–embryonic stem cell fusion

  2013cites this paper
• Genetic manipulations restored the growth fitness of reduced-genome Escherichia coli.

  2013cites this paper
• Yeast (YAC) and Human (HAC) Artificial Chromosome Clones

  2013cites this paper
• Meta-omic characterization of prokaryotic gene clusters for natural product biosynthesis.

  2013cites this paper
• lymphocytic leukemia Role for CCG-trinucleotide repeats in the pathogenesis of chronic

  2013cites this paper
• Recombinational cloning of the antibiotic biosynthetic gene clusters in linear plasmid SCP1 of Streptomyces coelicolor A3(2).

  2013cites this paper
• 19p13and CD23 Form a Cluster on Cutting Edge: DC-SIGN; a Related Gene,

  2013cites this paper
• An easy and versatile 2-step protocol for targeted modification and subcloning of DNA from bacterial artificial chromosomes using non-commercial plasmids

  2012cites this paper
• An arrayed human genomic library constructed in the PAC shuttle vector pJCPAC-Mam2 for genome-wide association studies and gene therapy.

  2012cites this paper
• Isolierung von DNA

  2012cites this paper
• Losing and finding myself in DNA repair.

  2012cites this paper
• Modelling Human Regulatory Variation in Mouse: Finding the Function in Genome-Wide Association Studies and Whole-Genome Sequencing

  2012cites this paper
• Fluorescence in situ hybridization for cancer-related studies.

  2012cites this paper
• An arrayed human genomic library constructed in the PAC shuttle vector pJCPAC-Mam2 for genome-wide association studies

  2012cites this paper
• Preparation of megabase-sized DNA from a variety of organisms using the nuclei method for advanced genomics research

  2012cites this paper
• The use of novel humanized mouse models and transcriptome characterization to study the neurogenesis factor, NR2E1, in brain and eye development

  2012cites this paper
• Construction of BIBAC and BAC libraries from a variety of organisms for advanced genomics research

  2012cites this paper
• Generation of HIV-1 Virus-Like Particles expressing different HIV-1 glycoproteins.

  2011cites this paper
• A One-Step Miniprep for the Isolation of Plasmid DNA and Lambda Phage Particles

  2011cites this paper
• Fate-mapping neural stem cells in the mouse ventral neural tube by Cre-lox transgenesis

  2011cites this paper
• High capacity vectors

  2011cites this paper
• Spatial and Temporal Regulation of Transgene Expression in Fish

  2011cites this paper
• FATTORI UMORALI PROTETTIVI COME STRUMENTI PER LA GENERAZIONE DI VACCINI EFFICACI CONTRO L'INFEZIONE DA HIV

  2011cites this paper
• Engineered plant minichromosomes.

  2011cites this paper
• Klonierungsvektoren für E. coli

  2011cites this paper
• Isolation of circular yeast artificial chromosomes for synthetic biology and functional genomics studies

  2011cites this paper
• Molekularzytogenetische Eingrenzung der Bruchpunkte von sieben krankheitsassoziierten chromosomalen Rearrangements

  2011cites this paper
• Plant Chromosome Engineering

  2011cites this paper
• Trial and Error: How the Unclonable Human Mitochondrial Genome was Cloned in Yeast

  2011cites this paper
• Delineating Chromosomal Breakpoints in Radiation-Induced Papillary Thyroid Cancer

  2011cites this paper
• Bacterial Genetics of Large Mammalian DNA Viruses: Bacterial Artificial Chromosomes as a Prerequisite for Efficiently Studying Viral DNA Replication and Functions

  2011cites this paper
• Engineered mammalian chromosomes in cellular protein production: future prospects.

  2011cites this paper
• Isolation of Specific Clones from Nonarrayed BAC Libraries through Homologous Recombination

  2010cites this paper
• Rapid bacterial artificial chromosome modification for large-scale mouse transgenesis

  2010cites this paper
• History of Industrial Biotechnology

  2010cites this paper
• Sequencing the Human Genome: Was It Worth It?

  2010cites this paper
• Generation and application of genomic tools as important prerequisites for sugar beet genome analyses.

  2010cites this paper
• Strategies for Map-Based Cloning in Apple

  2010cites this paper
• Escherichia coli-Cloned CFTR Loci Relevant for Human Artificial Chromosome Therapy

  2010influential citation
• Genetic Engineering Workshop Report, 2010

  2010cites this paper
• Cloning and mapping of the human SOX1: a highly conserved gene expressed in the developing brain

  2009cites this paper
• Best Practice & Research Clinical Gastroenterology

  2009cites this paper
• Familial adenomatous polyposis.

  2009cites this paper
• DETERMINING GENE COPY NUMBER IN TRANSFECTED CAPRINE FIBROBLAST CELLS

  2009cites this paper
• IRS-PCR-based genetic mapping of the huntingtin interacting protein gene (HIP1) on mouse Chromosome 5

  2009cites this paper
• PCR-based cloning of the complete mouse mitochondrial genome and stable engineering in Escherichia coli

  2009cites this paper
• Localization of the cell death genes CPP32 and Mch-2 to human Chromosome 4q

  2009cites this paper
• Seamless manipulation of the varicella-zoster virus genome via bacterial artificial chromosome engineering

  2009cites this paper
• Mapping and phenotyping genes in the Del(13)Svea36H region of mouse chromosome 13

  2009cites this paper
• TMTI Task 1.6 Genetic Engineering Methods and Detection

  2009cites this paper
• Regulated expression of a transgene introduced on an oriP/EBNA-1 PAC shuttle vector into human cells

  2009cites this paper
• A simple TAE-based method to generate large insert BAC libraries from plant species.

  2009cites this paper
• Advances in high-capacity extrachromosomal vector technology: episomal maintenance, vector delivery, and transgene expression.

  2008cites this paper
• Milestones Identifying Self-Incompatibility Genes in Brassica Species: From Old Stories to New Findings

  2008cites this paper
• The development of a novel and efficient HAC vector delivery system to human cells

  2008cites this paper
• Mutagenesis of the cytomegalovirus genome.

  2008cites this paper
• The Human Genome Project

  2008cites this paper
• Sequenz und Struktur des Pro-Enteropeptidase-Gens als Basis für Mutationsanalysen bei angeborenem Enteropeptidasemangel

  2008cites this paper
• Genomic complexity of the variable region-containing chitin-binding proteins in amphioxus

  2008cites this paper
• Single‐cell gel electrophoresis (the comet assay): Loops or fragments?

  2008cites this paper