The A3 Adenosine Receptor: History and Perspectives

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Pharmacological Reviews

• Publication date

  2015-01-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1124/pr.113.008540PMID 25387804
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Induction of Apoptosis.

  2016cited by this paper
• Induction of Apoptosis

  2016cited by this paper
• Spinal neuroimmune activation is independent of T-cell infiltration and attenuated by A3 adenosine receptor agonists in a model of oxaliplatin-induced peripheral neuropathy.

  2015cited by this paper
• Combination of Cl-IB-MECA with paclitaxel is a highly effective cytotoxic therapy causing mTOR-dependent autophagy and mitotic catastrophe on human melanoma cells

  2014cited by this paper
• Effect of a toggle switch mutation in TM6 of the human adenosine A3 receptor on Gi protein-dependent signalling and Gi-independent receptor internalization

  2014cited by this paper
• Allosteric interactions at adenosine A1 and A3 receptors: new insights into the role of small molecules and receptor dimerization

  2014cited by this paper
• Cardioprotection during chemotherapy: A case study to understand intracellular mechanisms to combat the cardiotoxicity of Sunitinib

  2014cited by this paper
• Synthesis and Anti-Renal Fibrosis Activity of Conformationally Locked Truncated 2-Hexynyl-N6-Substituted-(N)-Methanocarba-nucleosides as A3 Adenosine Receptor Antagonists and Partial Agonists

  2014cited by this paper
• Using caffeine and other adenosine receptor antagonists and agonists as therapeutic tools against neurodegenerative diseases: a review.

  2014cited by this paper
• A3 Adenosine receptors mediate oligodendrocyte death and ischemic damage to optic nerve

  2014cited by this paper
• A3 adenosine receptor agonist prevents the development of paclitaxel‐induced neuropathic pain by modulating spinal glial‐restricted redox‐dependent signaling pathways

  2014cited by this paper
• The role of activated adenosine receptors in degranulation of human LAD2 mast cells

  2014cited by this paper
• 20 Cardioprotection During Chemotherapy: A Case Study to Understand Intracellular Mechanisms to Combat the Cardiotoxicity of Sunitinib

  2014cited by this paper
• Adenosine A2B and A3 receptor location at the mouse neuromuscular junction

  2014cited by this paper
• Caspase Inhibition Via A3 Adenosine Receptors: A New Cardioprotective Mechanism Against Myocardial Infarction

  2014cited by this paper
• Purinergic Signaling and Blood Vessels in Health and Disease

  2014cited by this paper
• Anti-inflammatory effects of inosine in allergic lung inflammation in mice: evidence for the participation of adenosine A2A and A3 receptors

  2013cited by this paper
• Adenosine-A3 receptors in neutrophil microdomains promote the formation of bacteria-tethering cytonemes

  2013cited by this paper
• Regulation of Inflammation by Adenosine

  2013cited by this paper
• Targeting the A3 adenosine receptor for glaucoma treatment (review).

  2013cited by this paper
• Enhancing pigmentation via activation of A3 adenosine receptors in B16 melanoma cells and in human skin explants

  2013cited by this paper
• Functional Tissue Engineering in Articular Cartilage Repair: Is There a Role for Electromagnetic Biophysical Stimulation?

  2013cited by this paper
• A(1) and A(3) adenosine receptors inhibit LPS-induced hypoxia-inducible factor-1 accumulation in murine astrocytes.

  2013cited by this paper
• A3 adenosine receptor mediates apoptosis in in vitro RCC4-VHL human renal cancer cells by up-regulating AMID expression.

  2013cited by this paper
• Functional and RNA Expression Profile of Adenosine Receptor Subtypes in Mouse Mesenteric Arteries

  2013cited by this paper
• The stimulation of A(3) adenosine receptors reduces bone-residing breast cancer in a rat preclinical model.

  2013cited by this paper
• Rational design of sulfonated A3 adenosine receptor-selective nucleosides as pharmacological tools to study chronic neuropathic pain.

  2013cited by this paper
• Thio-Cl-IB-MECA, a novel A₃ adenosine receptor agonist, suppresses angiogenesis by regulating PI3K/AKT/mTOR and ERK signaling in endothelial cells.

  2013cited by this paper
• Differential effect of adenosine receptors on growth of human colon cancer HCT 116 and HT-29 cell lines.

  2013cited by this paper
• Adenosine—a physiological or pathophysiological agent?

  2013cited by this paper
• Novel effects of adenosine receptors on pericellular hyaluronan matrix: implications for human smooth muscle cell phenotype and interactions with monocytes during atherosclerosis

  2013cited by this paper
• Adenosine A3 receptor activation attenuates lung ischemia-reperfusion injury.

  2013cited by this paper
• Inosine induces presynaptic inhibition of acetylcholine release by activation of A3 adenosine receptors at the mouse neuromuscular junction

  2013cited by this paper
• Immunity, inflammation and cancer: a leading role for adenosine

  2013cited by this paper
• Pulsed Electromagnetic Fields Increased the Anti-Inflammatory Effect of A2A and A3 Adenosine Receptors in Human T/C-28a2 Chondrocytes and hFOB 1.19 Osteoblasts

  2013cited by this paper
• Purinergic Signaling in the Airways

  2012cited by this paper
• AMP Converted from Intracellularly Transported Adenosine Upregulates p53 Expression to Induce Malignant Pleural Mesothelioma Cell Apoptosis

  2012cited by this paper
• Apoptosis-Related Gene Transcription in Human A549 Lung Cancer Cells via A3 Adenosine Receptor

  2012cited by this paper
• Adenosine Induces Apoptosis in SBC-3 Human Lung Cancer Cells through A3 Adenosine Receptor-Dependent AMID Upregulation

  2012cited by this paper
• Adoptive Immunotherapy with Cl-IB-MECA-Treated CD8+ T Cells Reduces Melanoma Growth in Mice

  2012cited by this paper
• Regulation of Foam Cells by Adenosine

  2012cited by this paper
• The Anti-Tumor Effect of A3 Adenosine Receptors Is Potentiated by Pulsed Electromagnetic Fields in Cultured Neural Cancer Cells

  2012cited by this paper
• Treatment of plaque‐type psoriasis with oral CF101: data from an exploratory randomized phase 2 clinical trial

  2012cited by this paper
• CF102 for the treatment of hepatocellular carcinoma: a phase I/II, open-label, dose-escalation study.

  2012cited by this paper
• A3 Adenosine Receptor-Mediated p53-Dependent Apoptosis in Lu-65 Human Lung Cancer Cells

  2012cited by this paper
• Electromagnetic fields (EMFs) and adenosine receptors modulate prostaglandin E2 and cytokine release in human osteoarthritic synovial fibroblasts

  2012cited by this paper
• Impairment of adenosine A3 receptor activity disrupts neutrophil migratory capacity and impacts innate immune function in vivo

  2012cited by this paper
• Medicinal chemistry of A₃ adenosine receptor modulators: pharmacological activities and therapeutic implications.

  2012cited by this paper
• From A1 to A3 en passant through A(2A) receptors in the hippocampus: pharmacological implications.

  2012cited by this paper
• Biased signalling and allosteric machines: new vistas and challenges for drug discovery

  2012cited by this paper
• Adenosine as an endogenous immunoregulator in cancer pathogenesis: where to go?

  2012cited by this paper
• The mechanism of beta-adrenergic preconditioning: roles for adenosine and ROS during triggering and mediation

  2012cited by this paper
• Cordycepin as a sensitizer to tumour necrosis factor (TNF)‐α‐induced apoptosis through eukaryotic translation initiation factor 2α (eIF2α)‐ and mammalian target of rapamycin complex 1 (mTORC1)‐mediated inhibition of nuclear factor (NF)‐κB

  2012cited by this paper
• Adenosine A3 receptor stimulation reduces muscle injury following physical trauma and is associated with alterations in the MMP/TIMP response.

  2012cited by this paper
• Adenosine A3 receptor is involved in ADP‐induced microglial process extension and migration

  2012cited by this paper
• Anti-ischemic effects of multivalent dendrimeric A₃ adenosine receptor agonists in cultured cardiomyocytes and in the isolated rat heart.

  2012cited by this paper
• Adenosine receptor expression in rheumatoid synovium: a basis for methotrexate action

  2012cited by this paper
• Pharmacological and therapeutic effects of A3 adenosine receptor agonists.

  2012cited by this paper
• Adenosine A(3) receptor-induced proliferation of primary human coronary smooth muscle cells involving the induction of early growth response genes.

  2012cited by this paper
• Protection from Myocardial Ischemia/Reperfusion Injury by a Positive Allosteric Modulator of the A3 Adenosine Receptor

  2012cited by this paper
• Controlling murine and rat chronic pain through A3 adenosine receptor activation

  2012cited by this paper
• Downregulation of A(1) and A(2B) adenosine receptors in human trisomy 21 mesenchymal cells from first-trimester chorionic villi.

  2012cited by this paper
• The Adenosine A3 Receptor Agonist Cl-IB-MECA Induces Cell Death Through Ca2+/ROS-Dependent Down Regulation of ERK and Akt in A172 Human Glioma Cells

  2012cited by this paper
• Selective Activation of Adenosine A2A Receptors on Immune Cells by a CD73-Dependent Prodrug Suppresses Joint Inflammation in Experimental Rheumatoid Arthritis

  2012cited by this paper
• Adenosine A2A and A3 Receptors Are Involved in the Human Endothelial Progenitor Cells Migration

  2012cited by this paper
• A(3) adenosine receptor: a plausible therapeutic target for cardio-protection in diabetes.

  2012cited by this paper
• Crystal Structure of the β2Adrenergic Receptor-Gs protein complex

  2011cited by this paper
• Molecular mechanisms of A3 adenosine receptor-induced G1 cell cycle arrest and apoptosis in androgen-dependent and independent prostate cancer cell lines: involvement of intrinsic pathway

  2011cited by this paper
• Colocalization and Regulated Physical Association of Presynaptic Serotonin Transporters with A3 Adenosine Receptors

  2011cited by this paper
• Adenosine and ATP receptors in the brain.

  2011cited by this paper
• Adenosine receptors and cancer.

  2011cited by this paper
• Expression of mRNA for adenosine A(1), A(2a), A(2b), and A(3) receptors in HL-60 cells: dependence on cell cycle phases.

  2011cited by this paper
• Inhibition of experimental auto-immune uveitis by the A3 adenosine receptor agonist CF101.

  2011cited by this paper
• Oxygen/Glucose Deprivation Induces a Reduction in Synaptic AMPA Receptors on Hippocampal CA3 Neurons Mediated by mGluR1 and Adenosine A3 Receptors

  2011cited by this paper
• International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors—An Update

  2011cited by this paper
• Functionally biased modulation of A(3) adenosine receptor agonist efficacy and potency by imidazoquinolinamine allosteric enhancers.

  2011cited by this paper
• A3 adenosine receptor agonist reduces brain ischemic injury and inhibits inflammatory cell migration in rats.

  2011cited by this paper
• A2A and A3 adenosine receptor expression in rheumatoid arthritis: upregulation, inverse correlation with disease activity score and suppression of inflammatory cytokine and metalloproteinase release

  2011cited by this paper
• A₃ receptors are overexpressed in pleura from patients with mesothelioma and reduce cell growth via Akt/nuclear factor-κB pathway.

  2011cited by this paper
• Disparity in FcεRI-Induced Degranulation of Primary Human Lung and Skin Mast Cells Exposed to Adenosine

  2011cited by this paper
• NADPH Oxidase Pathway Is Involved in Aortic Contraction Induced by A3 Adenosine Receptor in Mice

  2011cited by this paper
• Differential Roles of GSK-3&bgr; During Myocardial Ischemia and Ischemia/Reperfusion

  2011cited by this paper
• Conformational changes in the G protein Gs induced by the β2 adrenergic receptor

  2011cited by this paper
• CF102 an A3 adenosine receptor agonist mediates anti‐tumor and anti‐inflammatory effects in the liver

  2011cited by this paper
• Investigational A3 adenosine receptor targeting agents

  2011cited by this paper
• Adenosine receptors and cancer.

  2011cited by this paper
• Cl-IB-MECA enhances TNF-α release in peritoneal macrophages stimulated with LPS.

  2011cited by this paper
• Impact of disrupting adenosine A3 receptors (A3−/−AR) on colonic motility or progression of colitis in the mouse

  2011cited by this paper
• Suppression of inflammation response by a novel A₃ adenosine receptor agonist thio-Cl-IB-MECA through inhibition of Akt and NF-κB signaling.

  2011cited by this paper
• Allosteric modulation of G protein-coupled receptors: a pharmacological perspective.

  2011cited by this paper
• Pharmacological characterization of adenosine receptors on isolated human bronchi.

  2011cited by this paper
• Polyamidoamine (PAMAM) dendrimer conjugate specifically activates the A3 adenosine receptor to improve post-ischemic/reperfusion function in isolated mouse hearts

  2011cited by this paper
• Adenosine receptor targeting in health and disease

  2011cited by this paper
• A3 RECEPTORS ARE OVEREXPRESSED IN PLEURA FROM PATIENTS WITH MESOTHELIOMA AND REDUCE CELL GROWTH VIA AKT/NUCLEAR FACTOR-KB PATHWAY

  2011cited by this paper
• Modulation of metalloproteinase-9 in U87MG glioblastoma cells by A3 adenosine receptors.

  2010cited by this paper
• Adenosine A1 and A3 receptor agonists reduce hypoxic injury through the involvement of P38 MAPK

  2010cited by this paper
• Dendrimer-based drug and imaging conjugates: design considerations for nanomedical applications.

  2010cited by this paper
• Oxidative/nitrosative stress selectively altered A2B adenosine receptors in chronic obstructive pulmonary disease

  2010cited by this paper
• GPCR ligand-dendrimer (GLiDe) conjugates: future smart drugs?

  2010cited by this paper
• Stimulation of the adenosine A3 receptor reverses vascular hyporeactivity after hemorrhagic shock in rats

  2010cited by this paper

• (N)-Methanocarba Adenosine Derivatives as Dual Modulators of P-Glycoprotein and ABCG2 Transporters.

  2026cites this paper
• Adenosine receptors as emerging therapeutic targets in epilepsy

  2026cites this paper
• Network toxicology reveals key genes of amiodarone induced pulmonary fibrosis: based on machine learning and SHAP analysis

  2026cites this paper
• Research Progress on the Role of Natural Active Substances in Regulating Adenosine Pathway in Tumor Therapy.

  2026cites this paper
• Role of A1 adenosine receptor in cardiovascular diseases: Bridging molecular mechanisms with therapeutic opportunities.

  2025cites this paper
• Structural Simplification from Tricyclic to Bicyclic Scaffolds: A Long-Term Investigation in the Field of Adenosine Receptor Antagonists

  2025cites this paper
• Molecular basis of ligand binding and receptor activation at the human A3 adenosine receptor

  2025cites this paper
• Exploring therapeutic mechanism of Fuzhenghefuzhiyang Formula in psoriasis: inflammation and metabolism regulation

  2025cites this paper
• Therapeutic potential of adenosine receptor modulators in cancer treatment

  2025cites this paper
• Adenosine in the Brain: Recent Progress on Detection, Function, and Translation

  2025cites this paper
• Steric influence of 4'-position substituents and C2-Hexynyl group on A3AR antagonism in truncated 4'-Thioadenosine derivatives.

  2025cites this paper
• The Secreted Metabolite Isopentenyladenine from Faecalibacterium prausnitzii Is Anti-inflammatory with Barrier-Protective Properties.

  2025cites this paper
• Adenosine and adenosine receptors: a “double-edged sword” in cardiovascular system

  2025cites this paper
• Special Issue “Molecular Research on Adenosine Receptors: From Cell Biology to Human Diseases”

  2025cites this paper
• Progress in the study of anti-Alzheimer's disease activity of pyrimidine-containing bioactive molecules.

  2025cites this paper
• Stromal Cells, Extracellular Matrix Components, and Adenosine A3 Receptor in Prostate Biopsies: Association With Histological Grade, PSA Levels, and Clinical Tumor Stage

  2025influential citation
• Transduction of Lentiviral Vectors and ADORA3 in HEK293T Cells Modulated in Gene Expression and Alternative Splicing

  2025cites this paper
• Dose-Dependent Interaction Between Caffeine and Morphine in Analgesia in the Hot-Plate in Mice.

  2025cites this paper
• Adenosine Receptor 3 in Liver Cancer: Expression Variability, Epigenetic Modulation, and Enhanced Histone Deacetylase Inhibitor Effects

  2024cites this paper
• Deep learning-assisted mass spectrometry imaging for preliminary screening and pre-classification of psychoactive substances.

  2024cites this paper
• Stereochemical influence of 4'-methyl substitutions on truncated 4'-thioadenosine derivatives: Impact on A3 adenosine receptor binding and antagonism.

  2024cites this paper
• Small molecule-based targeted therapy in liver cancer.

  2024cites this paper
• Photoswitchable Diazocine Derivative for Adenosine A3 Receptor Activation in Psoriasis

  2024cites this paper
• Manual acupuncture ameliorates inflammatory pain by upregulating adenosine A3 receptor in complete Freund's adjuvant-induced arthritis rats.

  2024cites this paper
• Current Understanding of the Role of Adenosine Receptors in Cancer

  2024cites this paper
• Hit-to-Lead Optimization of Heterocyclic Carbonyloxycarboximidamides as Selective Antagonists at Human Adenosine A3 Receptor

  2024cites this paper
• O Sistema Adenosina como Alvo na Busca de uma Nova Classe de Anti-Hipertensivos

  2024cites this paper
• Adenosine relaxes vagina smooth muscle through the cyclic guanosine monophosphate- and cyclic guanosine monophosphate-dependent pathways.

  2024cites this paper
• Adenosine A3 Receptor: From Molecular Signaling to Therapeutic Strategies for Heart Diseases

  2024cites this paper
• Role and mechanisms of mast cells in brain disorders

  2024cites this paper
• Adenosine receptors in breast cancer

  2024cites this paper
• Genetic and functional modulation by agonist MRS5698 and allosteric enhancer LUF6000 at the native A3 adenosine receptor in HL-60 cells

  2024cites this paper
• Targeting the adenosine signaling pathway in macrophages for cancer immunotherapy.

  2024cites this paper
• Cryo-EM structures of adenosine receptor A3AR bound to selective agonists

  2024cites this paper
• Adenosine and Its Receptors in the Pathogenesis and Treatment of Inflammatory Skin Diseases

  2024cites this paper
• Translational Experimental Basis of Indirect Adenosine Receptor Agonist Stimulation for Bone Regeneration: A Review

  2024cites this paper
• Bridging the translational gap: adenosine as a modulator of neuropathic pain in preclinical models and humans

  2023cites this paper
• Namodenoson Inhibits the Growth of Pancreatic Carcinoma via Deregulation of the Wnt/β-catenin, NF-κB, and RAS Signaling Pathways

  2023cites this paper
• Adenosine signaling inhibits erythropoiesis and promotes myeloid differentiation

  2023cites this paper
• Endless Journey of Adenosine Signaling in Cardioprotective Mechanism of Conditioning Techniques: Clinical Evidence

  2023cites this paper
• Assay-Dependent Inverse Agonism at the A3 Adenosine Receptor: When Neutral Is Not Neutral.

  2023cites this paper
• Covalently Binding Adenosine A3 Receptor Agonist ICBM Irreversibly Reduces Voltage-Gated Ca2+ Currents in Dorsal Root Ganglion Neurons

  2023cites this paper
• Combination immunotherapy of PEG-modified preladenant thermosensitive liposomes and PD-1 inhibitor effectively enhances the anti-tumor immune response and therapeutic effects

  2023cites this paper
• [1,2,4]Triazolo[1,5‐c]pyrimidines as Tools to Investigate A3 Adenosine Receptors in Cancer Cell Lines

  2023cites this paper
• Update on the recent development of allosteric modulators for adenosine receptors and their therapeutic applications

  2022cites this paper
• Dual A1/A3 Adenosine Receptor Antagonists: Binding Kinetics and Structure-Activity Relationship Studies Using Mutagenesis and Alchemical Binding Free Energy Calculations.

  2022cites this paper
• Structure-Activity Studies of 1H-Imidazo[4,5-c]quinolin-4-amine Derivatives as A3 Adenosine Receptor Positive Allosteric Modulators.

  2022cites this paper
• ASSOCIATE EDITOR: ELIOT OHLSTEIN International Union of Basic andClinical Pharmacology. CXII: Adenosine Receptors: A Further Update

  2022cites this paper
• A Selective Adenosine A3 Receptor Antagonist, HL3501, Has Therapeutic Potential in Preclinical Liver and Renal Fibrosis Models

  2022cites this paper
• Mechanisms underlying paclitaxel-induced neuropathic pain: Channels, inflammation and immune regulations.

  2022cites this paper
• A novel GRK2 inhibitor alleviates experimental arthritis trough restraining Th17 cell differentiation.

  2022cites this paper
• Adenosine as a Key Mediator of Neuronal Survival in Cerebral Ischemic Injury

  2022cites this paper
• Purinergic receptors modulators: An emerging pharmacological tool for disease management

  2022cites this paper
• Drugs Targeting the A3 Adenosine Receptor: Human Clinical Study Data

  2022cites this paper
• Pathophysiological Role and Medicinal Chemistry of A2A Adenosine Receptor Antagonists in Alzheimer’s Disease

  2022cites this paper
• m6A in the Signal Transduction Network

  2022cites this paper
• A2A Adenosine Receptor: A Possible Therapeutic Target for Alzheimer’s Disease by Regulating NLRP3 Inflammasome Activity?

  2022cites this paper
• 2-Cl-IB-MECA regulates the proliferative and drug resistance pathways, and facilitates chemosensitivity in pancreatic and liver cancer cell lines

  2022cites this paper
• C2‐linked alkynyl poly‐ethylene glycol(PEG) adenosine conjugates as water‐soluble adenosine receptor agonists

  2022cites this paper
• Interaction of A3 adenosine receptor ligands with the human multidrug transporter ABCG2.

  2022cites this paper
• A3 adenosine receptor agonist IB-MECA reverses chronic cerebral ischemia-induced inhibitory avoidance memory deficit.

  2022cites this paper
• Species dependence of A3 adenosine receptor pharmacology and function

  2022cites this paper
• DPCPX induces Bim‐dependent apoptosis in nasopharyngeal carcinoma cells

  2022cites this paper
• The role of peripheral adenosine receptors in glutamate-induced pain nociceptive behavior

  2021cites this paper
• Efficient G protein coupling is not required for agonist‐mediated internalization and membrane reorganization of the adenosine A3 receptor

  2021cites this paper
• Potential and promising anticancer drugs from adenosine and its analogs.

  2021cites this paper
• LJ529 attenuates mast cell-related inflammation via A3R-PKCε-ALDH2 pathway after subarachnoid hemorrhage in rats.

  2021cites this paper
• Design and Synthesis of 2,6-Disubstituted-4′-Selenoadenosine-5′-N,N-Dimethyluronamide Derivatives as Human A3 Adenosine Receptor Antagonists

  2021cites this paper
• Adenosine A3 agonists reverse neuropathic pain via T cell-mediated production of IL-10.

  2021cites this paper
• Potent and selective A3 adenosine receptor antagonists bearing aminoesters as heterobifunctional moieties.

  2021cites this paper
• Selected β2-, β3- and β2,3-Amino Acid Heterocyclic Derivatives and Their Biological Perspective

  2021cites this paper
• Advance of structural modification of nucleosides scaffold

  2021cites this paper
• Organometallic nucleosides—Synthesis, transformations, and applications

  2021cites this paper
• Cancer biology and molecular genetics of A3 adenosine receptor

  2021cites this paper
• Adenosine receptor antagonists: Recent advances and therapeutic perspective.

  2021cites this paper
• Nervous System-Systemic Crosstalk in SARS-CoV-2/COVID-19: A Unique Dyshomeostasis Syndrome

  2021cites this paper
• Pulsed Electromagnetic Fields: A Novel Attractive Therapeutic Opportunity for Neuroprotection After Acute Cerebral Ischemia.

  2021cites this paper
• Remote but not Distant: a Review on Experimental Models and Clinical Trials in Remote Ischemic Conditioning as Potential Therapy in Ischemic Stroke

  2021cites this paper
• Subtle Chemical Changes Cross the Boundary between Agonist and Antagonist: New A3 Adenosine Receptor Homology Models and Structural Network Analysis Can Predict This Boundary.

  2021cites this paper
• The clinical impact of maternal weight on offspring health: lights and shadows in breast milk metabolome

  2021cites this paper
• Synthesis and evaluation of adenosine derivatives as A1, A2A, A2B and A3 adenosine receptor ligands containing boron clusters as phenyl isosteres and selective A3 agonists.

  2021cites this paper
• Adenosine: The common target between cancer immunotherapy and glaucoma in the eye.

  2021cites this paper
• Adenosine Signaling in Mast Cells and Allergic Diseases

  2021influential citation
• Tart Cherry (Fruit of Prunus cerasus) Concentrated Powder (TCcp) Ameliorates Glucocorticoid-Induced Muscular Atrophy in Mice

  2021cites this paper
• Two New Adenosine Derivatives and their Antiproliferative Properties, an In Vitro Evaluation.

  2021cites this paper
• Adenosine and Inflammation: Here, There and Everywhere

  2021cites this paper
• The Medicinal Chemistry of Caffeine.

  2021cites this paper
• Novel Pyrazolo[3,4-c]pyridine Antagonists with Nanomolar affinity for A1 / A3 Adenosine Receptors: Binding Kinetics and Exploration of their Binding Profile Using Mutagenesis Experiments, MD simulations and TI/MD calculations

  2021cites this paper
• LJ-2698, an Adenosine A3 Receptor Antagonist, Alleviates Elastase-Induced Pulmonary Emphysema in Mice

  2020cites this paper
• Keep an eye on adenosine: Its role in retinal inflammation.

  2020cites this paper
• Opposing Effects of Adenosine and Inosine in Human Subcutaneous Fibroblasts May Be Regulated by Third Party ADA Cell Providers

  2020cites this paper
• Synthesis of Novel Potent Archazolids: Pharmacology of an Emerging Class of Anticancer Drugs.

  2020cites this paper
• Characteristics and the role of purinergic receptors in pathophysiology with focus on immune response

  2020cites this paper
• Activation of adenosine A3 receptors regulates vitamin C transport and redox balance in neurons.

  2020cites this paper
• Pre- and post-conditioning of the heart: an overview of cardioprotective signaling pathways.

  2020cites this paper
• N6-methyladenosine (m6A) is an endogenous A3 adenosine receptor ligand

  2020cites this paper
• Pharmacology of Adenosine Receptors

  2020cites this paper
• Adenosine in the lateral hypothalamus/perifornical area does not participate on the CO2 chemoreflex.

  2020cites this paper
• Research Pipeline I: Oral Therapeutics for Psoriasis

  2020cites this paper
• Antinociceptive and neurochemical effects of a single dose of IB-MECA in chronic pain rat models

  2020cites this paper