ATP-binding cassette (ABC) transporters in human metabolism and diseases.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Physiological Research

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 15209530
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Heritability of plasma noncholesterol sterols and relationship to DNA sequence polymorphism in ABCG5 and ABCG8.

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• Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells.

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• Membrane Lipid Domains Distinct from Cholesterol/Sphingomyelin-Rich Rafts Are Involved in the ABCA1-mediated Lipid Secretory Pathway*

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  2000cited by this paper
• Cholesterol efflux to apolipoprotein AI involves endocytosis and resecretion in a calcium-dependent pathway

  2000cited by this paper
• ABCA1-mediated transport of cellular cholesterol and phospholipids to HDL apolipoproteins.

  2000cited by this paper
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  1999cited by this paper
• Tangier disease is caused by mutations in the gene encoding ATP-binding cassette transporter 1

  1999cited by this paper
• Cholesterol efflux to apolipoprotein AI involves endocytosis and resecretion in a calcium-dependent pathway.

  1999cited by this paper
• The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease

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• Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency

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• Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis.

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• [Tangier disease (familial high density lipoprotein deficiency)].

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  1998cited by this paper
• A multidrug resistance transporter from human MCF-7 breast cancer cells.

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• A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

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• Mutations in the Canalicular Multispecific Organic Anion Transporter (cMOAT) Gene, a Novel ABC Transporter, in Patients with Hyperbilirubinemia II/Dubin-Johnson Syndrome

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• Corrigendum: A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy

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• Apolipoprotein-mediated removal of cellular cholesterol and phospholipids.

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• MDR1 P-glycoprotein is a lipid translocase of broad specificity, while MDR3 P-glycoprotein specifically translocates phosphatidylcholine.

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• Primary structure of a novel ABC transporter with a chromosomal localization on the band encoding the multidrug resistance‐associated protein

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• Sequence comparison of yeast ATP-binding cassette proteins.

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• Evolution of ATP-binding cassette transporter genes.

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• HDL-mediated efflux of intracellular cholesterol is impaired in fibroblasts from Tangier disease patients.

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• The ABC of channel regulation.

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• Cloning of two novel ABC transporters mapping on human chromosome 9.

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• Putative X-linked adrenoleukodystrophy gene shares unexpected homology with ABC transporters

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• Sitosterolemia.

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• High density lipoprotein apolipoproteins mediate removal of sterol from intracellular pools but not from plasma membranes of cholesterol-loaded fibroblasts.

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• Decreased cholesterol biosynthesis in sitosterolemia with xanthomatosis: diminished mononuclear leukocyte 3-hydroxy-3-methylglutaryl coenzyme A reductase activity and enzyme protein associated with increased low-density lipoprotein receptor function.

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• Structural model of ATP-binding proteing associated with cystic fibrosis, multidrug resistance and bacterial transport

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• Multiple mutations in highly conserved residues are found in mildly affected cystic fibrosis patients.

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• The biochemistry of P-glycoprotein-mediated multidrug resistance.

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• P‐glycoprotein: multidrug‐resistance and a superfamily of membrane‐associated transport proteins

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• Increased sitosterol absorption, decreased removal, and expanded body pools compensate for reduced cholesterol synthesis in sitosterolemia with xanthomatosis.

  1989cited by this paper
• Binding of high density lipoproteins to cell receptors promotes translocation of cholesterol from intracellular membranes to the cell surface.

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• Abnormal metabolism of shellfish sterols in a patient with sitosterolemia and xanthomatosis.

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• A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants.

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• Tangier disease (familial high density lipoprotein deficiency). Clinical and genetic features in two adults.

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