Transition from SCLC to NSCLC phenotype is accompanied by an increased TRE-binding activity and recruitment of specific AP-1 proteins

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Oncogene

• Publication date

  1998-06-11

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/sj.onc.1201845PMID 9662339
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Variations in Jun and Fos protein expression and AP-1 activity in cycling, resting and stimulated fibroblasts

  1997cited by this paper
• Transformation by ras modifies AP1 composition and activity

  1997cited by this paper
• Cell-substratum interactions mediate oncogene-induced phenotype of lung cancer cells.

  1996cited by this paper
• Receptor-Ligand Interaction Between CD44 and Osteopontin (Eta-1)

  1996cited by this paper
• Requirement of an Upstream AP-1 Motif for the Constitutive and Phorbol Ester-inducible Expression of the Urokinase-type Plasminogen Activator Receptor Gene*

  1996cited by this paper
• Expression of CD44 splice variants in normal respiratory epithelium and bronchial carcinomas: no evidence for altered CD44 splicing in metastasis.

  1996cited by this paper
• Transcriptional control by protein phosphorylation: signal transmission from the cell surface to the nucleus.

  1995cited by this paper
• Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation.

  1995cited by this paper
• Transcriptional regulation by extracellular signals: mechanisms and specificity.

  1995cited by this paper
• Fos-related Antigen (Fra-1), junB, and junD Activate Human Involucrin Promoter Transcription by Binding to Proximal and Distal AP1 Sites to Mediate Phorbol Ester Effects on Promoter Activity (*)

  1995cited by this paper
• Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis

  1994cited by this paper
• Expression of CD44 in human lung tumors.

  1994cited by this paper
• Activated ras and src induce CD44 overexpression in rat intestinal epithelial cells.

  1994cited by this paper
• Mouse JunD negatively regulates fibroblast growth and antagonizes transformation by ras.

  1994cited by this paper
• Prolonged expression of c-jun and associated activity of the transcription factor AP-1, during apoptosis in a human leukaemic cell line.

  1994cited by this paper
• Hyaluronate receptors: key players in growth, differentiation, migration and tumor progression.

  1994cited by this paper
• Interleukin 6 induces DNA binding activity of AP1 in M1 myeloblastic cells but not in a growth resistant cell derivative.

  1993cited by this paper
• Stable murine chondrogenic cell lines derived from c‐fos‐induced cartilage tumors

  1993cited by this paper
• Localization of Fos and Jun proteins in rat aortic smooth muscle cells after vascular injury.

  1993cited by this paper
• Expression of c-fos and related genes in the rat heart in response to norepinephrine.

  1993cited by this paper
• Regulation of transcription factor mRNA accumulation during 3T3-L1 preadipocyte differentiation by antagonists of adipogenesis

  1993cited by this paper
• A novel small-cell lung carcinoma-specific DNA-binding activity related to the transcription factor ap-1.

  1993cited by this paper
• Brain transcription factor expression: effects of acute and chronic amphetamine and injection stress.

  1993cited by this paper
• The NFAT-1 DNA binding complex in activated T cells contains Fra-1 and JunB

  1993cited by this paper
• A link between ras and metastatic behavior of tumor cells: ras induces CD44 promoter activity and leads to low-level expression of metastasis-specific variants of CD44 in CREF cells.

  1993cited by this paper
• Continuous c-fos expression precedes programmed cell death in vivo

  1993cited by this paper
• A selective transcriptional induction system for mammalian cells based on Gal4-estrogen receptor fusion proteins.

  1993cited by this paper
• Regulatory mechanism of 92 kDa type IV collagenase gene expression which is associated with invasiveness of tumor cells.

  1993cited by this paper
• Lymphocyte CD44 binds the COOH-terminal heparin-binding domain of fibronectin

  1992cited by this paper
• Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons.

  1992cited by this paper
• Inhibition of myogenesis by okadaic acid, an inhibitor of protein phosphatases, 1 and 2A, correlates with the induction of AP1.

  1992cited by this paper
• Existence of different Fos/Jun complexes during the G0-to-G1 transition and during exponential growth in mouse fibroblasts: differential role of Fos proteins

  1992cited by this paper
• c-myc gene-induced alterations in protein kinase C expression: a possible mechanism facilitating myc-ras gene complementation.

  1991cited by this paper
• Difference in transcriptional regulatory function between c-Fos and Fra-2.

  1991cited by this paper
• Downstream sequences mediate induction of the mouse cathepsin L promoter by phorbol esters.

  1991cited by this paper
• c-JUN, JUN B, and JUN D differ in their binding affinities to AP-1 and CRE consensus sequences: effect of FOS proteins.

  1991cited by this paper
• The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation.

  1991cited by this paper
• The transmembrane hyaluronate receptor (CD44): multiple functions, multiple forms.

  1991cited by this paper
• Transitions between lung cancer phenotypes--implications for tumor progression.

  1991cited by this paper
• Isolation of human fos-related genes and their expression during monocyte-macrophage differentiation.

  1990cited by this paper
• Mapping of functional domains in Fos and Jun proteins using epitope-specific antibodies.

  1990cited by this paper
• Isolation and characterization of fra-2, an additional member of the fos gene family.

  1990cited by this paper
• CD44 is the principal cell surface receptor for hyaluronate.

  1990cited by this paper
• A Set of Human Putative Lymphocyte G0/G1 Switch Genes Includes Genes Homologous to Rodent Cytokine and Zinc Finger Protein-Encoding Genes

  1990cited by this paper
• Expression of CD44 confers a new adhesive phenotype on transfected cells.

  1990cited by this paper
• v-rasH induces non-small cell phenotype, with associated growth factors and receptors, in a small cell lung cancer cell line.

  1990cited by this paper
• Isolation of human cDNA clones of jun-related genes, jun-B and jun-D.

  1990cited by this paper
• jun-D: a third member of the jun gene family.

  1989cited by this paper
• Asymmetrical recognition of the palindromic AP1 binding site (TRE) by Fos protein complexes.

  1989cited by this paper
• Characterization of junD: a new member of the jun proto‐oncogene family.

  1989cited by this paper
• The antimitogenic action of tumor necrosis factor is associated with increased AP-1/c-jun proto-oncogene transcription.

  1989cited by this paper
• A family of octamer‐specific proteins present during mouse embryogenesis: evidence for germline‐specific expression of an Oct factor.

  1989cited by this paper
• The product of a novel growth factor activated gene, fos B, interacts with JUN proteins enhancing their DNA binding activity.

  1989cited by this paper
• Growth factors regulate transin gene expression by c-fos-dependent and c-fos-independent pathways.

  1988cited by this paper
• fra-1: a serum-inducible, cellular immediate-early gene that encodes a fos-related antigen

  1988cited by this paper
• DNA binding activities of three murine Jun proteins: stimulation by Fos.

  1988cited by this paper
• Structure and chromosomal localization of the functional intronless human JUN protooncogene.

  1988cited by this paper
• v-Ha-ras oncogene insertion: a model for tumor progression of human small cell lung cancer.

  1988cited by this paper
• Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1.

  1987cited by this paper
• Mutually exclusive interaction of the CCAAT-binding factor and of a displacement protein with overlapping sequences of a histone gene promoter.

  1987cited by this paper
• Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor.

  1987cited by this paper
• Lung cancer heterogeneity: a blinded and randomized study of 100 consecutive cases.

  1985cited by this paper
• The complete sequence of a full length cDNA for human liver glyceraldehyde-3-phosphate dehydrogenase: evidence for multiple mRNA species.

  1984cited by this paper
• Complete nucleotide sequence of a human c-onc gene: deduced amino acid sequence of the human c-fos protein.

  1983cited by this paper

• Molecular basis and therapeutic implications of binary YAPOn/YAPOff cancer classes

  2025cites this paper
• Comprehensive analysis of single-cell transcriptomics and genetic factors reveals the mechanisms and preventive strategies for the progression from pulmonary fibrosis to lung cancer.

  2024cites this paper
• Archetype tasks link intratumoral heterogeneity to plasticity and cancer hallmarks in small cell lung cancer.

  2022cites this paper
• The role of AP-1 in self-sufficient proliferation and migration of cancer cells and its potential impact on an autocrine/paracrine loop

  2018cites this paper
• FOSL1 Promotes Kras‐induced Lung Cancer through Amphiregulin and Cell Survival Gene Regulation

  2017cites this paper
• The Pathobiology of the Breast Cancer Invasive Process

  2016cites this paper
• Characterizing the role of p21-Activated Kinase 3 (PAK3) in AP-1-induced transformation

  2014cites this paper
• p21-Activated Kinase 3 (PAK3) Is an AP-1 Regulated Gene Contributing to Actin Organisation and Migration of Transformed Fibroblasts

  2013cites this paper
• Inducible expression of tissue factor in small-cell lung cancer: impact on morphology and matrix metalloproteinase secretion

  2012cites this paper
• Molecular and Cellular Characteristics of Small Cell Lung Cancer: Implications for Molecular-Targeted Cancer Therapy

  2012cites this paper
• Cell Specific CD44 Expression in Breast Cancer Requires the Interaction of AP-1 and NFκB with a Novel cis-Element

  2012cites this paper
• The PKCθ pathway participates in the aberrant accumulation of Fra-1 protein in invasive ER-negative breast cancer cells

  2012cites this paper
• The molecular role of Fra‐1 and its prognostic significance in human esophageal squamous cell carcinoma

  2012cites this paper
• Fos-related antigen-1 (Fra-1) is a regulator of glioma cell malignant phenotype

  2011cites this paper
• Inhibition of AP-1 suppresses cervical cancer cell proliferation and is associated with p21 expression

  2011cites this paper
• Ü-BOEFT#JPTDJFODF %POPUEJTUSJCVUF

  2011cites this paper
• Evodiamine Inhibits 12‐O‐Tetradecanoylphorbol‐13‐acetate‐induced Activator Protein 1 Transactivation and Cell Transformation in Human Hepatocytes

  2011cites this paper
• Knockdown of the c-Jun-N-terminal kinase expression by siRNA inhibits MCF-7 breast carcinoma cell line growth.

  2010cites this paper
• MicroRNA expression distinguishes SCLC from NSCLC lung tumor cells and suggests a possible pathological relationship between SCLCs and NSCLCs

  2010cites this paper
• Oral Administration of Blueberry Inhibits Angiogenic Tumor Growth and Enhances Survival of Mice with Endothelial Cell Neoplasm

  2009cites this paper
• Expression and Significance of FRA-1 in Non-Small-Cell Lung Cancer

  2009cites this paper
• Phenotypic variations and chemosensitivity in small cell lung cancer

  2008cites this paper
• Redox Regulation of Angiogenesis: Anti-Angiogenic Properties of Edible Berries and Its Significance in a Clinical Setting

  2007cites this paper
• FRA-1 proto-oncogene induces lung epithelial cell invasion and anchorage-independent growth in vitro, but is insufficient to promote tumor growth in vivo.

  2007cites this paper
• Hint1 inhibits growth and activator protein-1 activity in human colon cancer cells.

  2007cites this paper
• In vivo Insufficient to Promote Tumor Growth , but Is In vitro Invasion and Anchorage-Independent Growth FRA-1 Proto-Oncogene Induces Lung Epithelial Cell

  2007cites this paper
• Variations in Free Radical Scavenging Capacity and Antiproliferative Activity Among Different Genotypes of Autumn Olive (Elaeagnus umbellata)

  2007cites this paper
• Variations in free radical scavenging capacity and antiproliferative activity among different genotypes of autumn olive (Elaeagnus umbellata).

  2007cites this paper
• Epithelial to mesenchymal transition in human breast epithelial cells transformed by 17beta-estradiol.

  2007cites this paper
• Functional transcriptomics: an experimental basis for understanding the systems biology for cancer cells.

  2007cites this paper
• Hint 1 Inhibits Growth and Activator Protein-1 Activity in Human Colon Cancer Cells

  2007cites this paper
• Oncogenic signaling pathways and deregulated target genes.

  2007cites this paper
• The Activator Protein-1 Transcription Factor in Respiratory Epithelium Carcinogenesis

  2007cites this paper
• Molecular characterization of cancer chemopreventive effects of anthocyans

  2006cites this paper
• DNA and DNA -interacting proteins as anticancer drug targets

  2006cites this paper
• Global Effects of Ras Signaling on the Genetic Program in Mammalian Cells

  2006cites this paper
• Fra-1 a target for cancer prevention or intervention.

  2006cites this paper
• RNA Interference Technology: Microarray analysis and RNA silencing to determine genes functionally important in mesothelioma

  2005cites this paper
• RNA Interference Technology: High-throughput genome-wide RNAi analysis

  2005cites this paper
• Functional network analysis reveals extended gliomagenesis pathway maps and three novel MYC-interacting genes in human gliomas.

  2005influential citation
• The Fos family of transcription factors and their role in tumourigenesis.

  2005cites this paper
• Transcriptional basis of KRAS oncogene-mediated cellular transformation in ovarian epithelial cells

  2004cites this paper
• TGF? Back to the Future: Revisiting its Role as a Transforming Growth Factor

  2004cites this paper
• 17Beta-estradiol enhances the production of nerve growth factor in THP-1-derived macrophages or peripheral blood monocyte-derived macrophages.

  2003cites this paper
• The small GTPase RhoA has greater expression in small cell lung carcinoma than in non-small cell lung carcinoma and contributes to their unique morphologies.

  2003cites this paper
• Anthocyanidins inhibit

  2003cites this paper
• Anthocyanidins inhibit activator protein 1 activity and cell transformation: structure-activity relationship and molecular mechanisms.

  2003cites this paper
• Accumulation of Fra-1 in ras-Transformed Cells Depends on Both Transcriptional Autoregulation and MEK-Dependent Posttranslational Stabilization

  2003cites this paper
• Histamine enhances the production of nerve growth factor in human keratinocytes.

  2003cites this paper
• 17β-Estradiol Enhances the Production of Nerve Growth Factor in THP-1-Derived Macrophages or Peripheral Blood Monocyte-Derived Macrophages

  2003cites this paper
• Positive and negative regulators of the vasopressin gene promoter in small cell lung cancer.

  2002cites this paper
• Chapter 26 Positive and negative regulators of the vasopressin gene promoter in small cell lung cancer

  2002cites this paper
• Deficiency of c-Jun-NH(2)-terminal kinase-1 in mice enhances skin tumor development by 12-O-tetradecanoylphorbol-13-acetate.

  2002cites this paper
• In vitro chemo- and radio-resistance in small cell lung cancer correlates with cell adhesion and constitutive activation of AKT and MAP kinase pathways

  2002cites this paper
• Role and regulation of activator protein-1 in toxicant-induced responses of the lung.

  2002cites this paper
• The ability of Fos family members to produce phenotypic changes in epithelioid cells is not directly linked to their transactivation potentials

  2002cites this paper
• Identification of Differentially Expressed Genes in Esophageal Squamous Cell Carcinoma ( ESCC ) by cDNA Expression Array : Overexpression of Fra-1 , Neogenin , Id-1 , and CDC 25 B Genes in ESCC 1

  2001cites this paper
• Axl receptor tyrosine kinase expression in human lung cancer cell lines correlates with cellular adhesion.

  2001cites this paper
• Identification of differentially expressed genes in esophageal squamous cell carcinoma (ESCC) by cDNA expression array: overexpression of Fra-1, Neogenin, Id-1, and CDC25B genes in ESCC.

  2001cites this paper
• Novel cross talk between MEK and S6K2 in FGF-2 induced proliferation of SCLC cells

  2001cites this paper
• A dominant role for the c-Jun NH2-terminal kinase in oncogenic ras-induced morphologic transformation of human lung carcinoma cells.

  2000cites this paper
• Constitutive achaete-scute homologue-1 promotes airway dysplasia and lung neuroendocrine tumors in transgenic mice.

  2000cites this paper
• Fos family members: regulation, structure and role in oncogenic transformation.

  2000cites this paper
• Stimulatory effect of oral administration of green tea or caffeine on ultraviolet light-induced increases in epidermal wild-type p53, p21(WAF1/CIP1), and apoptotic sunburn cells in SKH-1 mice.

  2000cites this paper
• Dysregulated activation of activator protein 1 in keratinocytes of atopic dermatitis patients with enhanced expression of granulocyte/macrophage-colony stimulating factor.

  2000cites this paper
• Role of activating protein‐1 and high mobility group‐I(Y) protein in the induction of CD44 gene expression by interleukin‐1β in vascular smooth muscle cells

  2000cites this paper
• Advances in Brief Constitutive Achaete-Scute Homologue-1 Promotes Airway Dysplasia and Lung Neuroendocrine Tumors in Transgenic Mice 1

  2000cites this paper
• Endogenous AP-1 levels necessary for oncogenic activity are higher than those sufficient to support normal growth.

  2000cites this paper
• Inhibition of activator protein 1 activity and cell growth by purified green tea and black tea polyphenols in H-ras-transformed cells: structure-activity relationship and mechanisms involved.

  1999cites this paper
• Mechanisms Involved-transformed Cells : Structure-Activity Relationship and ras Purified Green Tea and Black Tea Polyphenols in H-Inhibition of Activator Protein 1 Activity and Cell Growth by Updated

  1999cites this paper
• E-box motifs within the human vasopressin gene promoter contribute to a major enhancer in small-cell lung cancer.

  1999cites this paper