Connections between single-cell biomechanics and human disease states: gastrointestinal cancer and malaria.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Acta Biomaterialia

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1016/J.ACTBIO.2004.09.001PMID 16701777
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Large deformation of living cells using laser traps

  2004cited by this paper
• The deformability of red blood cells parasitized by Plasmodium falciparum and P. vivax.

  2004influential reference
• The malaria-infected red blood cell: Structural and functional changes

  2004cited by this paper
• Nonlinear elastic and viscoelastic deformation of the human red blood cell with optical tweezers.

  2004cited by this paper
• Cell and molecular mechanics of biological materials

  2003cited by this paper
• Mechanics of the human red blood cell deformed by optical tweezers

  2003influential reference
• α4β1 Integrin/Ligand Interaction Inhibits α5β1-induced Stress Fibers and Focal Adhesions via Down-Regulation of RhoA and Induces Melanoma Cell Migration

  2003cited by this paper
• Alpha4beta1 integrin/ligand interaction inhibits alpha5beta1-induced stress fibers and focal adhesions via down-regulation of RhoA and induces melanoma cell migration.

  2003cited by this paper
• The biomechanics toolbox: experimental approaches for living cells and biomolecules

  2003cited by this paper
• Sphingosylphosphorylcholine regulates keratin network architecture and visco-elastic properties of human cancer cells

  2003influential reference
• The pathogenic basis of malaria

  2002influential reference
• Central role of the spleen in malaria parasite clearance.

  2002cited by this paper
• Mechanical signaling and the cellular response to extracellular matrix in angiogenesis and cardiovascular physiology.

  2002cited by this paper
• Contribution of parasite proteins to altered mechanical properties of malaria-infected red blood cells.

  2002influential reference
• Mechanics of the Cell

  2002cited by this paper
• Contribution of the nucleus to the mechanical properties of endothelial cells.

  2002cited by this paper
• Histamine stimulates phosphorylation of adherens junction proteins and alters their link to vimentin.

  2002cited by this paper
• Sphingosylphosphocholine is a naturally occurring lipid mediator in blood plasma: a possible role in regulating cardiac function via sphingolipid receptors.

  2001cited by this paper
• Rapid stiffening of integrin receptor-actin linkages in endothelial cells stimulated with thrombin: a magnetic bead microrheology study.

  2001cited by this paper
• The optical stretcher: a novel laser tool to micromanipulate cells.

  2001cited by this paper
• Multifaceted physiological response allows yeast to adapt to the loss of the signal recognition particle-dependent protein-targeting pathway.

  2001cited by this paper
• A comparison of the in vivo kinetics of Plasmodium falciparum ring-infected erythrocyte surface antigen-positive and -negative erythrocytes.

  2001influential reference
• Electrospray ionization mass spectrometry analysis of lysophospholipids in human ascitic fluids: comparison of the lysophospholipid contents in malignant vs nonmalignant ascitic fluids.

  2001cited by this paper
• Abnormal blood flow and red blood cell deformability in severe malaria.

  2000cited by this paper
• Sphingosylphosphorylcholine induces endothelial cell migration and morphogenesis.

  2000cited by this paper
• Commitment to sexual differentiation in the human malaria parasite, Plasmodium falciparum

  2000cited by this paper
• A brief illustrated guide to the ultrastructure of Plasmodium falciparum asexual blood stages.

  2000cited by this paper
• Sphingosylphosphorylcholine in Niemann-Pick Disease Brain: Accumulation in Type A But Not in Type B

  1999cited by this paper
• Elasticity of the red cell membrane and its relation to hemolytic disorders: an optical tweezers study.

  1999cited by this paper
• A new determination of the shear modulus of the human erythrocyte membrane using optical tweezers.

  1999cited by this paper
• Measurement of local viscoelasticity and forces in living cells by magnetic tweezers.

  1999cited by this paper
• Microplates: a new tool for manipulation and mechanical perturbation of individual cells.

  1999cited by this paper
• Time scale dependent viscoelastic and contractile regimes in fibroblasts probed by microplate manipulation.

  1997cited by this paper
• Demonstration of mechanical connections between integrins, cytoskeletal filaments, and nucleoplasm that stabilize nuclear structure.

  1997cited by this paper
• In vitro susceptibility studies of Plasmodium falciparum isolates and clones against type II antifolate drugs.

  1996cited by this paper
• Intermediate filaments: structure, dynamics, function, and disease.

  1994cited by this paper
• Lysophosphatidic acid stimulates tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130. Signaling pathways and cross-talk with platelet-derived growth factor.

  1994cited by this paper
• Membrane rigidity of red blood cells parasitized by different strains of Plasmodium falciparum.

  1993cited by this paper
• The ring-infected erythrocyte surface antigen of Plasmodium falciparum associates with spectrin in the erythrocyte membrane.

  1991cited by this paper
• APlasmodium falciparum exo‐antigen alters erythrocyte membrane deformability

  1991cited by this paper
• Sphingosylphosphorylcholine is a remarkably potent mitogen for a variety of cell lines.

  1991cited by this paper
• Boekbespreking: Molecular biology of the cell, B. Alberts, D. Bray, J. Lewis, M. Raff, K. Robers, D.J. Watson. Garland Publ., New York. 1989.

  1990cited by this paper
• Genetic analysis of the human malaria parasite Plasmodium falciparum.

  1987cited by this paper
• Plasmodium falciparum maturation abolishes physiologic red cell deformability.

  1984cited by this paper
• Membrane viscoelasticity.

  1976cited by this paper
• Human malaria parasites in continuous culture.

  1976cited by this paper

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