The Cold Origin of Life: A. Implications Based On The Hydrolytic Stabilities Of Hydrogen Cyanide And Formamide

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Origins of life and evolution of the biosphere

• Publication date

  2002-06-01

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1023/A:1016514305984PMID 12227424
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Energy yields for hydrogen cyanide and formaldehyde syntheses: The hcn and amino acid concentrations in the primitive ocean

  2006cited by this paper
• Carbon dioxide on the early earth

  2005cited by this paper
• Was ferrocyanide a prebiotic reagent?

  2005influential reference
• The origin of life—did it occur at high temperatures?

  2004cited by this paper
• The Cold Origin of Life: B. Implications Based on Pyrimidines and Purines Produced From Frozen Ammonium Cyanide Solutions

  2002cited by this paper
• Primordial carbonylated iron-sulfur compounds and the synthesis of pyruvate.

  2000cited by this paper
• Abiotic Synthesis of Guanine with High-Temperature Plasma

  2000cited by this paper
• Prebiotic synthesis of adenine and amino acids under Europa-like conditions.

  2000cited by this paper
• Mechanisms of amino acid formation using optical emission spectroscopy

  1999cited by this paper
• Origin and Ancestor: Separate Environments

  1999cited by this paper
• Production of guanine from NH(4)CN polymerizations.

  1999cited by this paper
• A nonhyperthermophilic common ancestor to extant life forms.

  1999cited by this paper
• Production of Guanine from NH4CN Polymerizations

  1999cited by this paper
• Cytosine and Uracil Synthesis by Quenching with High-Temperature Plasma

  1999cited by this paper
• Elongation of oligopeptides in a simulated submarine hydrothermal system.

  1999cited by this paper
• Amino acid synthesis from an amorphous substance composed of carbon, nitrogen, and oxygen

  1998cited by this paper
• PYROLYTIC BEHAVIOR OF AMINO ACIDS AND NUCLEIC ACID BASES : IMPLICATIONS FOR THEIR SURVIVAL DURING EXTRATERRESTRIAL DELIVERY

  1998cited by this paper
• Peptides by activation of amino acids with CO on (Ni,Fe)S surfaces: implications for the origin of life.

  1998cited by this paper
• Glycolonitrile oligomerization: structure of isolated oxazolines, potential heterocycles on the early earth.

  1997cited by this paper
• Activated acetic acid by carbon fixation on (Fe,Ni)S under primordial conditions.

  1997cited by this paper
• A hot topic: the origin of hyperthermophiles.

  1996cited by this paper
• Impact melting of frozen oceans on the early Earth: Implications for the origin of life

  1994influential reference
• Archean geochemistry of formaldehyde and cyanide and the oligomerization of cyanohydrin

  1994cited by this paper
• Susceptibility of the early Earth to irreversible glaciation caused by carbon dioxide clouds

  1992cited by this paper
• Endogenous production, exogenous delivery and impact-shock synthesis of organic molecules: an inventory for the origins of life

  1992cited by this paper
• Origin of life--facing up to the physical setting.

  1991cited by this paper
• Cometary delivery of organic molecules to the early Earth.

  1990cited by this paper
• Geochemical constraints on the origin of organic compounds in hydrothermal systems

  1990cited by this paper
• Impact delivery and erosion of planetary oceans in the early inner Solar System

  1990cited by this paper
• Pre-biotic organic matter from comets and asteroids

  1989cited by this paper
• Impact Delivery and Erosion of Planetary Oceans

  1989cited by this paper
• Annihilation of ecosystems by large asteroid impacts on the early Earth

  1989cited by this paper
• Submarine hot springs and the origin of life

  1988cited by this paper
• Impact frustration of the origin of life

  1988cited by this paper
• Origin of the eukaryotic nucleus determined by rate-invariant analysis of rRNA sequences

  1988cited by this paper
• Destruction of cyanides by thermal hydrolysis

  1987cited by this paper
• The implication of the oxygen isotope records in coexisting cherts and phosphates

  1986cited by this paper
• Climatic consequences of very high carbon dioxide levels in the earth's early atmosphere.

  1986cited by this paper
• Solvent Effect on the Kinetic Study of the Alkaline Hydrolysis of Formamide in Acetone‐Water Mixtures

  1985cited by this paper
• HCN and chemical evolution: the possible role of cyano compounds in prebiotic synthesis.

  1984cited by this paper
• Hydrolytic stability of biomolecules at high temperatures and its implication for life at 250 degrees C.

  1984cited by this paper
• Acid Catalysed Amide Hydrolysis in Water-Ethanol Mixtures. Medium Interactions Study

  1984cited by this paper
• Hydrolytic stability of biomolecules at high temperatures and its implication for life at 250 °C

  1984cited by this paper
• The atmospheric chemistry of hydrogen cyanide (HCN)

  1983cited by this paper
• Prebiotic synthesis in atmospheres containing CH4, CO, and CO2

  1983cited by this paper
• Kinetics & Mechanism of Acid Hydrolysis of Formamide, Acetamide, Propanarnide & Butanamide over an Extended Concentration Range: Kinetic Evidence for Fast Protonation Pre-equilibrium

  1982cited by this paper
• Uracil synthesis via HCN oligomerization.

  1982cited by this paper
• HYDROLYSIS OF FORMAMIDE AT 80°C AND PH 1-9

  1981cited by this paper
• Rates of fixation by lightning of carbon and nitrogen in possible primitive atmospheres

  1981cited by this paper
• Hydrolysis of formamide at 80.degree.C and pH 1-9

  1981cited by this paper
• An Hypothesis Concerning the Relationships Between Submarine Hot Springs and the Origin of Life on Earth

  1981cited by this paper
• Detection of carbon-13-nitrogen-15 coupled units in adenine derived from doubly labeled hydrogen cyanide or formamide

  1978cited by this paper
• Spontaneous phosphorylation of nucleosides in formamide—Ammonium phosphate mixtures

  1977cited by this paper
• The Origins of Life on the Earth

  1974cited by this paper
• Additions and Corrections - Equilibrium and Kinetics of Glyconitrile Formation in Aqueous Solution.

  1973cited by this paper
• A facile one-step synthesis of adenine

  1968cited by this paper
• Studies in prebiotic synthesis. VI. Synthesis of purine nucleosides.

  1968cited by this paper
• Ammonium Ion Concentration in the Primitive Ocean

  1968cited by this paper
• Studies in prebiotic synthesis. II. Synthesis of purine precursors and amino acids from aqueous hydrogen cyanide.

  1967influential reference
• Comets and the Formation of Biochemical Compounds on the Primitive Earth

  1961cited by this paper
• Synthesis of adenine from ammonium cyanide

  1960cited by this paper
• THE HYDROLYSIS OF ALIPHATIC NITRILES IN CONCENTRATED HYDROCHLORIC ACID SOLUTIONS

  1942cited by this paper
• The Hydrolysis of Nitriles with Acids

  1939cited by this paper
• NON-ELECTROLYTE SOLUTIONS

  1934cited by this paper
• The Hydrolysis of Hydrogen Cyanide by Acids. II

  1929cited by this paper

• How Does Adenine Form from Hydrogen Cyanide?

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  2025cites this paper
• Cyanide Storage on Ferroan Brucite (MgxFe1−x(OH)2): Implications for Prebiotic Chemistry

  2025cites this paper
• Constraining the survival of HCN during cometary impacts

  2025cites this paper
• Divergent freezing behavior in nanoconfinement: organic vs. salt aqueous mixtures.

  2025cites this paper
• Autocatalytic Reaction between HCN and Cysteamine Produces Hydrophobic, Catalytic, Liquid Compartments

  2025cites this paper
• Revealing and Mitigating Crossover-Driven Side Reactions in Ferrocyanide-Based Redox Flow Batteries

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• UV Transmission in Prebiotic Environments on Early Earth

  2024cites this paper
• New Estimates of Nitrogen Fixation on Early Earth

  2024cites this paper
• Enceladus: Astrobiology Revisited

  2024cites this paper
• Different Scenarios for the Origin and the Subsequent Succession of a Hypothetical Microbial Community in the Cloud Layer of Venus

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• Favorable Environments for the Formation of Ferrocyanide, a Potentially Critical Reagent for Origins of Life

  2024cites this paper
• A Surface Hydrothermal Source of Nitriles and Isonitriles

  2024cites this paper
• Do-Nothing Prebiotic Chemistry: Chemical Kinetics as a Window into Prebiotic Plausibility

  2024cites this paper
• The plausibility of origins scenarios requiring two impactors

  2024influential citation
• One-pot synthesis of non-canonical ribonucleosides and their precursors from aldehydes and ammonia under prebiotic Earth conditions

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• Eta-Earth Revisited II: Deriving a Maximum Number of Earth-Like Habitats in the Galactic Disk

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• Multicomponent Synthesis of C(8)‐Substituted Purine Building Blocks of Peptide Nucleic Acids from Prebiotic Compounds

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  2023cites this paper
• Evaluating the abiotic synthesis potential and the stability of building blocks of life beneath an impact-induced steam atmosphere

  2023cites this paper
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  2023cites this paper
• Formamide-Based Post-impact Thermal Prebiotic Synthesis in Simulated Craters: Intermediates, Products and Mechanism

  2022cites this paper
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  2022cites this paper
• Dissipative Photochemical Abiogenesis of the Purines

  2022cites this paper
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  2022cites this paper
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  2022cites this paper
• Can prebiotic systems survive in the wild? An interference chemistry approach

  2022cites this paper
• The role of borosilicate glass in Miller–Urey experiment

  2021cites this paper
• The Prebiotic Kitchen: A Guide to Composing Prebiotic Soup Recipes to Test Origins of Life Hypotheses

  2021cites this paper
• A Lizardite–HCN Interaction Leading the Increasing of Molecular Complexity in an Alkaline Hydrothermal Scenario: Implications for Origin of Life Studies

  2021cites this paper
• Illuminating Life’s Origins: UV Photochemistry in Abiotic Synthesis of Biomolecules

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• The Dissipative Photochemical Origin of Life: UVC Abiogenesis of Adenine

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• Prebiotic Organic Chemistry of Formamide and the Origin of Life in Planetary Conditions: What We Know and What Is the Future

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• Energy at Origins: Favorable Thermodynamics of Biosynthetic Reactions in the Last Universal Common Ancestor (LUCA)

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• Primordial Radioactivity and Prebiotic Chemical Evolution: Effect of γ Radiation on Formamide-based Synthesis.

  2020cites this paper
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• A sensitive quantitative analysis of abiotically synthesized short homopeptides using ultraperformance liquid chromatography and time-of-flight mass spectrometry.

  2020cites this paper
• Cometary Delivery of Hydrogen Cyanide to the Early Earth

  2020cites this paper
• Structure, Stability and Spectroscopic Properties of Small Acetonitrile Cation Clusters.

  2020cites this paper
• Chemical evolution: from formamide to nucleobases and amino acids without the presence of catalyst

  2020cites this paper
• Bioenergetic constraints on the origin of autotrophic metabolism

  2020cites this paper
• Photochemical Dissipative Structuring, Proliferation and Evolution at the Origin of Life

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• Thresholds in Origin of Life Scenarios

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• Self‐catalytic mechanism of prebiotic reactions: From formamide to purine bases

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  2020cites this paper
• An experimental study of the thermolysis of hydrogen cyanide: the role of hydrothermal systems in chemical evolution

  2020cites this paper
• Thermodynamics of Prebiotic Phosphorylation.

  2019cites this paper
• Origin and Evolution of Life-Related Molecules

  2019cites this paper
• Impact of space weather on climate and habitability of terrestrial-type exoplanets

  2019influential citation
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• When Did Life Likely Emerge on Earth in an RNA‐First Process?

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• Pressure-induced Freeze Concentration of Alanine Aqueous Solution as a Novel Field of Chemical Reaction

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• Origins of building blocks of life: A review

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  2017influential citation
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  2016cites this paper
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• Prebiotic synthesis of nucleic acids and their building blocks at the atomic level - merging models and mechanisms from advanced computations and experiments.

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• Snow and ice ecosystems: not so extreme.

  2015cites this paper
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  2015cites this paper
• Desorption electrospray ionization imaging of small organics on mineral surfaces.

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  2015cites this paper
• Formamide reaction network in gas phase and solution via a unified theoretical approach: Toward a reconciliation of different prebiotic scenarios

  2015cites this paper
• Prebiotic systems chemistry: new perspectives for the origins of life.

  2014cites this paper
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