Lesions of the ventral premammillary nucleus disrupt the dynamic changes in Kiss1 and GnRH expression characteristic of the proestrus-estrus transition.

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Neuroscience

• Publication date

  2013-06-25

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.neuroscience.2013.03.013PMID 23518222PMCID PMC3661013
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Neuroendocrine Control of the Ovarian Cycle of the Rat

  2015influential reference
• Leptin action via hypothalamic nitric oxide synthase-1 neurons controls energy balance

  2012cited by this paper
• The nitric oxide pathway participates in lordosis behavior induced by central administration of leptin.

  2012cited by this paper
• Faculty Opinions recommendation of Leptin action through hypothalamic nitric oxide synthase-1-expressing neurons controls energy balance.

  2012cited by this paper
• Leptin facilitates lordosis behavior through GnRH-1 and progestin receptors in estrogen-primed rats.

  2011cited by this paper
• Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons.

  2011cited by this paper
• Characterization of Kiss1 neurons using transgenic mouse models.

  2011cited by this paper
• The Ventral Premammillary Nucleus Links Metabolic Cues and Reproduction

  2011cited by this paper
• Histaminergic regulation of seasonal metabolic rhythms in Siberian hamsters

  2011cited by this paper
• Distribution of mRNAs encoding classical progestin receptor, progesterone membrane components 1 and 2, serpine mRNA binding protein 1, and progestin and ADIPOQ receptor family members 7 and 8 in rat forebrain.

  2011cited by this paper
• Male and female odors induce Fos expression in chemically defined neuronal population.

  2010influential reference
• Neurobiological mechanisms underlying kisspeptin activation of gonadotropin-releasing hormone (GnRH) neurons at puberty.

  2010cited by this paper
• Hypothalamic Sites of Leptin Action Linking Metabolism and Reproduction

  2010influential reference
• Leptin induces phosphorylation of neuronal nitric oxide synthase in defined hypothalamic neurons.

  2010cited by this paper
• Physiological roles of the kisspeptin/GPR54 system in the neuroendocrine control of reproduction.

  2010cited by this paper
• The Ventral Premammillary Nucleus Links Fasting-Induced Changes in Leptin Levels and Coordinated Luteinizing Hormone Secretion

  2009influential reference
• Sex and regional differences in decrease of estrogen receptor alpha-immunoreactive cells by estrogen in rat hypothalamus and midbrain.

  2009influential reference
• Direct Innervation of GnRH Neurons by Metabolic- and Sexual Odorant-Sensing Leptin Receptor Neurons in the Hypothalamic Ventral Premammillary Nucleus

  2009cited by this paper
• Regulation of Gonadotropin-Releasing Hormone Secretion by Kisspeptin/Dynorphin/Neurokinin B Neurons in the Arcuate Nucleus of the Mouse

  2009cited by this paper
• Kisspeptin signaling in the brain.

  2009cited by this paper
• Kisspeptin–GPR54 Signaling Is Essential for Preovulatory Gonadotropin-Releasing Hormone Neuron Activation and the Luteinizing Hormone Surge

  2008cited by this paper
• Estrogen positive feedback to gonadotropin-releasing hormone (GnRH) neurons in the rodent: the case for the rostral periventricular area of the third ventricle (RP3V).

  2008influential reference
• Involvement of anteroventral periventricular metastin/kisspeptin neurons in estrogen positive feedback action on luteinizing hormone release in female rats.

  2007cited by this paper
• CHAPTER 43 – Neuroendocrine Control of the Ovarian Cycle of the Rat

  2006influential reference
• Female odors stimulate CART neurons in the ventral premammillary nucleus of male rats.

  2006cited by this paper
• Definition of estrogen receptor pathway critical for estrogen positive feedback to gonadotropin-releasing hormone neurons and fertility.

  2006cited by this paper
• Kiss1 Neurons in the Forebrain as Central Processors for Generating the Preovulatory Luteinizing Hormone Surge

  2006cited by this paper
• RNAi-mediated silencing of estrogen receptor α in the ventromedial nucleus of hypothalamus abolishes female sexual behaviors

  2006cited by this paper
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  2006cited by this paper
• CHAPTER 34 – Hormonal, Neural, and Genomic Mechanisms for Female Reproductive Behaviors, Motivation, and Arousal

  2006influential reference
• Indirect projections from the suprachiasmatic nucleus to major arousal-promoting cell groups in rat: implications for the circadian control of behavioural state.

  2005cited by this paper
• Characterization of the potent luteinizing hormone-releasing activity of KiSS-1 peptide, the natural ligand of GPR54.

  2005cited by this paper
• Regulation of Kiss1 gene expression in the brain of the female mouse.

  2005cited by this paper
• Involvement of central metastin in the regulation of preovulatory luteinizing hormone surge and estrous cyclicity in female rats.

  2005cited by this paper
• The GPR54 gene as a regulator of puberty.

  2004cited by this paper
• Hypothalamic cocaine- and amphetamine-regulated transcript neurons project to areas expressing gonadotropin releasing hormone immunoreactivity and to the anteroventral periventricular nucleus in male and female rats.

  2004cited by this paper
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  2004cited by this paper
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  2004cited by this paper
• Distribution of estrogen receptor α and β in the mouse central nervous system: In vivo autoradiographic and immunocytochemical analyses

  2004cited by this paper
• A role for kisspeptins in the regulation of gonadotropin secretion in the mouse.

  2004cited by this paper
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  2003cited by this paper
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  2003cited by this paper
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  1999cited by this paper
• Differential distribution and regulation of estrogen receptor-alpha and -beta mRNA within the female rat brain.

  1998influential reference
• Differential distribution and regulation of estrogen receptor-α and -β mRNA within the female rat brain

  1998influential reference
• Implications of immediate-early gene induction in the brain following sexual stimulation of female and male rodents.

  1997cited by this paper
• Leptin facilitates and inhibits sexual behavior in female hamsters.

  1997cited by this paper
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  1997cited by this paper
• Ovarian Steroid Regulation of Estrogen and Progesterone Receptor Messenger Ribonucleic Acid in the Anteroventral Periventricular Nucleus of the Rat

  1996influential reference
• Fos immunoreactivity in the rat brain following consummatory elements of sexual behavior: a sex comparison.

  1996influential reference
• Increased GnRH mRNA in the GnRH neurons expressing cFos during the proestrous LH surge.

  1995influential reference
• PCR differential display identifies a rat brain mRNA that is transcriptionally regulated by cocaine and amphetamine

  1995influential reference
• Gene expression in a subpopulation of luteinizing hormone-releasing hormone (LHRH) neurons prior to the preovulatory gonadotropin surge

  1994cited by this paper
• Sexual stimulation activates c-fos within estrogen-concentrating regions of the female rat forebrain.

  1993cited by this paper
• Projections of the ventral premammillary nucleus

  1992cited by this paper
• Dynamics of gonadotropin-releasing hormone (GnRH) secretion during the GnRH surge: insights into the mechanism of GnRH surge induction.

  1992influential reference
• Regulation of estrogen receptor messenger ribonucleic acid in rat hypothalamus by sex steroid hormones.

  1991influential reference
• Modes of estrus induction as a factor in studies of the reproductive behavior of rodents.

  1990cited by this paper
• Gonadotropin-releasing hormone gene expression during the rat estrous cycle: effects of pentobarbital and ovarian steroids.

  1990cited by this paper
• Distribution of androgen and estrogen receptor mRNA‐containing cells in the rat brain: An in situ hybridization study

  1990cited by this paper
• Paced copulation in rats: effects of intromission frequency and duration on luteal activation and estrus length.

  1989cited by this paper
• The rat gonadotropin-releasing hormone: SH locus: structure and hypothalamic expression.

  1989cited by this paper
• Transmitter and peptide actions on hypothalamic neurons in vitro: implications for lordosis.

  1988cited by this paper
• Differential effects of electrolytic and chemical hypothalamic lesions on LH pulses in rats.

  1988cited by this paper
• Immunocytochemical localization of progesterone receptor in the guinea pig central nervous system.

  1986cited by this paper
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  1985cited by this paper
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  1985cited by this paper
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  1983cited by this paper
• The Rat Brain in Stereotaxic Coordinates

  1983cited by this paper
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  1982cited by this paper
• Luteinizing hormone-releasing hormone release during the rat estrous cycle and after ovariectomy, as estimated with push-pull cannulae.

  1982influential reference
• Progestin receptor levels in rat hypothalamic and limbic nuclei

  1982cited by this paper
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  1982influential reference
• Rostral medial preoptic area lesions' influence on female estrous processes and LHRH distribution.

  1981cited by this paper
• Serum levels of oestradiol-17 beta and progesterone in relation to sexual receptivity in intact and ovariectomized rats.

  1981cited by this paper
• LH-RH in the mesencephalic central grey can potentiate lordosis reflex of female rats

  1980cited by this paper
• Sexual behavior of male and female septal lesioned rats.

  1980cited by this paper
• Oestrogen modulates progestin receptor concentrations in some rat brain regions but not in others

  1978influential reference
• Potentiation of lordosis behavior by intrahypothalamic infusion of synthetic luteinizing hormone-releasing hormone.

  1976cited by this paper
• Induction of Mating Behavior in Rats by Luteinizing Hormone-Releasing Factor

  1973cited by this paper
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  1973cited by this paper
• The effect of copulatory behavior on hormonal change in the female rat prior to implantation.

  1970cited by this paper
• Stimulation of female sex behavior in adrenalectomized rats with estrogen alone.

  1968cited by this paper

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