Measurements of tumor vascular leakiness using DCE in brain tumors: clinical applications

No abstract is available for this paper.

• Publication year

  2013

• Venue

  NMR in Biomedicine

• Publication date

  2013-08-01

• Fields of study

  Medicine, Engineering

• Identifiers
  DOI 10.1002/nbm.2994PMID 23832526
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Prognostic vascular imaging biomarkers in high-grade gliomas: tumor permeability as an adjunct to blood volume estimates.

  2013cited by this paper
• Imaging vascular function for early stage clinical trials using dynamic contrast-enhanced magnetic resonance imaging

  2012cited by this paper
• Tracer kinetic modelling in MRI: estimating perfusion and capillary permeability

  2012cited by this paper
• Model selection for DCE‐T1 studies in glioblastoma

  2012cited by this paper
• Distinguishing recurrent high-grade gliomas from radiation injury: a pilot study using dynamic contrast-enhanced MR imaging.

  2011cited by this paper
• Diagnostic Dilemma of Pseudoprogression in the Treatment of Newly Diagnosed Glioblastomas: The Role of Assessing Relative Cerebral Blood Flow Volume and Oxygen-6-Methylguanine-DNA Methyltransferase Promoter Methylation Status

  2011cited by this paper
• Potential for differentiation of pseudoprogression from true tumor progression with dynamic susceptibility-weighted contrast-enhanced magnetic resonance imaging using ferumoxytol vs. gadoteridol: a pilot study.

  2011cited by this paper
• Potential for differentiation of pseudoprogression from true tumor progression with dynamic susceptibility-weighted contrast-enhanced magnetic resonance imaging using ferumoxytol versus gadoteridol: A pilot study

  2011cited by this paper
• The paradoxical effect of bevacizumab in the therapy of malignant gliomas

  2011cited by this paper
• Permeability Estimates in Histopathology-Proved Treatment-Induced Necrosis Using Perfusion CT: Can These Add to Other Perfusion Parameters in Differentiating from Recurrent/Progressive Tumors?

  2011cited by this paper
• The paradoxical effect of bevacizumab in the therapy of malignant gliomas

  2011cited by this paper
• Differentiating treatment-induced necrosis from recurrent/progressive brain tumor using nonmodel-based semiquantitative indices derived from dynamic contrast-enhanced T1-weighted MR perfusion.

  2011cited by this paper
• Microvascular leakage and contrast enhancement as prognostic factors for recurrence in unfavorable low-grade gliomas

  2010cited by this paper
• Pancreatic cancer: utility of dynamic contrast-enhanced MR imaging in assessment of antiangiogenic therapy.

  2010cited by this paper
• Enhancing Fraction in Glioma and Its Relationship to the Tumoral Vascular Microenvironment: A Dynamic Contrast-Enhanced MR Imaging Study

  2010cited by this paper
• Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group.

  2010cited by this paper
• Parametric response map as an imaging biomarker to distinguish progression from pseudoprogression in high-grade glioma.

  2010cited by this paper
• Dynamic MRI Using Iron Oxide Nanoparticles to Assess Early Vascular Effects of Antiangiogenic versus Corticosteroid Treatment in a Glioma Model

  2009cited by this paper
• Differentiation of recurrent glioblastoma multiforme from radiation necrosis after external beam radiation therapy with dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging.

  2009cited by this paper
• Description of magnetic resonance imaging‐derived enhancement variables in pathologically confirmed prostate cancer and normal peripheral zone regions

  2009cited by this paper
• Semiquantitative and quantitative dynamic contrast-enhanced magnetic resonance imaging measurements predict radiation response in cervix cancer.

  2009cited by this paper
• A "vascular normalization index" as potential mechanistic biomarker to predict survival after a single dose of cediranib in recurrent glioblastoma patients.

  2009cited by this paper
• Relative Cerebral Blood Volume Values to Differentiate High-Grade Glioma Recurrence from Posttreatment Radiation Effect: Direct Correlation between Image-Guided Tissue Histopathology and Localized Dynamic Susceptibility-Weighted Contrast-Enhanced Perfusion MR Imaging Measurements

  2009cited by this paper
• Quantitative Estimation of Permeability Surface-Area Product in Astroglial Brain Tumors Using Perfusion CT and Correlation with Histopathologic Grade

  2008cited by this paper
• Distinguishing Recurrent Intra-Axial Metastatic Tumor from Radiation Necrosis Following Gamma Knife Radiosurgery Using Dynamic Susceptibility-Weighted Contrast-Enhanced Perfusion MR Imaging

  2008cited by this paper
• Gliomas: predicting time to progression or survival with cerebral blood volume measurements at dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging.

  2008cited by this paper
• Vascular permeability during antiangiogenesis treatment: MR imaging assay results as biomarker for subsequent tumor growth in rats.

  2008cited by this paper
• Antiangiogenic tumor treatment: early noninvasive monitoring with USPIO-enhanced MR imaging in mice.

  2007cited by this paper
• Differentiation of Glioblastoma Multiforme and Single Brain Metastasis by Peak Height and Percentage of Signal Intensity Recovery Derived from Dynamic Susceptibility-Weighted Contrast-Enhanced Perfusion MR Imaging

  2007cited by this paper
• Dynamic Contrast Enhanced Magnetic Resonance Imaging in Oncology: Theory, Data Acquisition, Analysis, and Examples.

  2007cited by this paper
• FIRST‐PASS PERFUSION COMPUTED TOMOGRAPHY: INITIAL EXPERIENCE IN DIFFERENTIATING RECURRENT BRAIN TUMORS FROM RADIATION EFFECTS AND RADIATION NECROSIS

  2007cited by this paper
• Dynamic contrast enhanced MRI in prostate cancer.

  2007cited by this paper
• AZD2171, a pan-VEGF receptor tyrosine kinase inhibitor, normalizes tumor vasculature and alleviates edema in glioblastoma patients.

  2007cited by this paper
• Permeability versus cerebral blood volume measurement in brain tumor evaluation: comparative clinical value and advice to authors.

  2006cited by this paper
• The extent and severity of vascular leakage as evidence of tumor aggressiveness in high-grade gliomas.

  2006cited by this paper
• Low-grade gliomas: dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging--prediction of patient clinical response.

  2006cited by this paper
• Do cerebral blood volume and contrast transfer coefficient predict prognosis in human glioma?

  2006cited by this paper
• A unified magnetic resonance imaging pharmacokinetic theory: Intravascular and extracellular contrast reagents

  2005cited by this paper
• Use of magnetic resonance imaging to assess blood-brain/blood-glioma barrier opening during conformal radiotherapy.

  2005cited by this paper
• Dynamic contrast-enhanced MR imaging kinetic parameters and molecular weight of dendritic contrast agents in tumor angiogenesis in mice.

  2005cited by this paper
• Contrast agents for imaging tumor angiogenesis: is bigger better?

  2005cited by this paper
• High‐resolution T1 and T2 mapping of the brain in a clinically acceptable time with DESPOT1 and DESPOT2

  2005cited by this paper
• The assessment of antiangiogenic and antivascular therapies in early-stage clinical trials using magnetic resonance imaging: issues and recommendations

  2005cited by this paper
• The role of blood-brain barrier permeability in brain tumor imaging and therapeutics.

  2005cited by this paper
• Quantification of angiogenesis by functional computed tomography in a Matrigel model in rats.

  2004cited by this paper
• Measuring blood volume and vascular transfer constant from dynamic, T  2* ‐weighted contrast‐enhanced MRI

  2004cited by this paper
• Dynamic, contrast‐enhanced perfusion MRI in mouse gliomas: Correlation with histopathology

  2003cited by this paper
• Characterization of time-enhancement curves of benign and malignant prostate tissue at dynamic MR imaging

  2003cited by this paper
• Reduction of vascular and permeable regions in solid tumors detected by macromolecular contrast magnetic resonance imaging after treatment with antiangiogenic agent TNP-470.

  2003cited by this paper
• CT imaging of angiogenesis.

  2003cited by this paper
• Variation of the relaxographic “shutter‐speed” for transcytolemmal water exchange affects the CR bolus‐tracking curve shape

  2003cited by this paper
• Imaging microvascular structure with contrast enhanced MRI.

  2003cited by this paper
• Breast MRI for monitoring response of primary breast cancer to neo-adjuvant chemotherapy

  2002cited by this paper
• Functional CT imaging of angiogenesis in rabbit VX2 soft-tissue tumour.

  2001cited by this paper
• Quantitative measurement of microvascular permeability in human brain tumors achieved using dynamic contrast-enhanced MR imaging: correlation with histologic grade.

  2000cited by this paper
• Estimating kinetic parameters from dynamic contrast‐enhanced t1‐weighted MRI of a diffusable tracer: Standardized quantities and symbols

  1999cited by this paper
• Dynamic breast MR imaging: are signal intensity time course data useful for differential diagnosis of enhancing lesions?

  1999cited by this paper
• Breast disease: dynamic spiral MR imaging.

  1998cited by this paper
• Primary breast abnormalities: selective pixel sampling on dynamic gadolinium-enhanced MR images.

  1998cited by this paper
• Modeling tracer kinetics in dynamic Gd‐DTPA MR imaging

  1997cited by this paper
• Tumor perfusion studies using fast magnetic resonance imaging technique in advanced cervical cancer: a new noninvasive predictive assay.

  1996cited by this paper
• Induction of vascular endothelial growth factor expression by hypoxia and by glucose deficiency in multicell spheroids: implications for tumor angiogenesis.

  1995cited by this paper
• Cerebral blood volume maps of gliomas: comparison with tumor grade and histologic findings.

  1994cited by this paper
• Radiation-induced telangiectasia in the brain simulates cryptic vascular malformations at MR imaging.

  1994cited by this paper
• The role of angiogenesis in tumor growth.

  1992cited by this paper
• Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo

  1992cited by this paper
• Measurement of the blood‐brain barrier permeability and leakage space using dynamic MR imaging. 1. Fundamental concepts

  1991cited by this paper
• The nature of latent cerebral irradiation damage and its modification by hypertension.

  1970cited by this paper
• Glioblastoma: A Feasibility Study Genes Related to Angiogenesis Regulation in Correlation of Perfusion Parameters with

  year unknowncited by this paper

• TAMing Gliomas: Unraveling the Roles of Iba1 and CD163 in Glioblastoma

  2025cites this paper
• Advances in Neuro-Oncological Imaging: An Update on Diagnostic Approach to Brain Tumors

  2024cites this paper
• Challenges, Limitations and Pitfalls of PET and Advanced MRI in Patients with Brain Tumors - A Report of the PET/RANO Group.

  2024cites this paper
• Microvessel barrier dysfunction in sinonasal inverted papilloma‐associated squamous cell carcinoma and its manifestation in dynamic contrast‐enhanced MRI

  2024cites this paper
• Integrative Magnetic Resonance Imaging and Metabolomic Characterization of a Glioblastoma Rat Model

  2024cites this paper
• Glioma grading using an optimized T1-weighted dynamic contrast-enhanced magnetic resonance imaging paradigm

  2024cites this paper
• Added value of dynamic contrast-enhanced MR imaging in deep learning-based prediction of local recurrence in grade 4 adult-type diffuse gliomas patients

  2024cites this paper
• Automatic removal of large blood vasculature for objective assessment of brain tumors using quantitative dynamic contrast‐enhanced magnetic resonance imaging

  2024cites this paper
• Beyond conventional imaging: Advancements in MRI for glioma malignancy prediction and molecular profiling.

  2024cites this paper
• Imaging blood-brain barrier dysfunction: A state-of-the-art review from a clinical perspective

  2023cites this paper
• Immune cell identity behind the Ktrans mapping of mouse glioblastoma.

  2023cites this paper
• A Novel Multi-Model High Spatial Resolution Method for Analysis of DCE MRI Data: Insights from Vestibular Schwannoma Responses to Antiangiogenic Therapy in Type II Neurofibromatosis

  2023cites this paper
• Current status of Cancer Nanotheranostics: Emerging strategies for cancer management

  2023influential citation
• Influence of scan duration on dynamic contrast -enhanced magnetic resonance imaging pharmacokinetic parameters for brain lesions.

  2023cites this paper
• Simultaneous Dual Echo Gadolinium Enhanced MR-PET for Evaluation of PET Tracer Delivery in Altered Pathophysiology

  2022cites this paper
• Temporal DCE Profile of Brain Metastasis with A Comparison of Pseudoprogression Cases

  2022cites this paper
• Cluster Analysis of DSC MRI, Dynamic Contrast-Enhanced MRI, and DWI Parameters Associated with Prognosis in Patients with Glioblastoma after Removal of the Contrast-Enhancing Component: A Preliminary Study

  2022cites this paper
• Liquid biopsies for early diagnosis of brain tumours: in silico mathematical biomarker modelling

  2022cites this paper
• Surrogate vascular input function measurements from the superior sagittal sinus are repeatable and provide tissue-validated kinetic parameters in brain DCE-MRI

  2022cites this paper
• Blood–brain barrier leakage years after pre‐eclampsia: dynamic contrast‐enhanced 7‐Tesla MRI study

  2022cites this paper
• MR diffusion and dynamic‐contrast enhanced imaging to distinguish meningioma, paraganglioma, and schwannoma in the cerebellopontine angle and jugular foramen

  2021cites this paper
• The LEGATOS technique: A new tissue‐validated dynamic contrast‐enhanced MRI method for whole‐brain, high‐spatial resolution parametric mapping

  2021cites this paper
• Intravoxel Incoherent Motion and Dynamic Contrast‐Enhanced Magnetic Resonance Imaging to Early Detect Tissue Injury and Microcirculation Alteration in Hepatic Injury Induced by Intestinal Ischemia–Reperfusion in a Rat Model

  2021cites this paper
• 7T dynamic contrast‐enhanced MRI for the detection of subtle blood–brain barrier leakage

  2021cites this paper
• Differentiating Glioblastoma from Primary Central Nervous System Lymphoma: the Value of Shapping and Nonenhancing Peritumoral Hyperintense Gyral Lesion on FLAIR Imaging.

  2021cites this paper
• Neurovascular Unit Alterations in the Growth-Restricted Newborn Are Improved Following Ibuprofen Treatment

  2021cites this paper
• Accelerated brain tumor dynamic contrast‐enhanced MRI using Adaptive Pharmaco‐Kinetic Model Constrained method

  2021cites this paper
• Advanced imaging techniques for neuro-oncologic tumor diagnosis, with an emphasis on PET-MRI imaging of malignant brain tumors

  2021cites this paper
• Prognostication of anaplastic astrocytoma patients: application of contrast leakage information of dynamic susceptibility contrast-enhanced MRI and dynamic contrast-enhanced MRI

  2020cites this paper
• Blood–Brain Barrier Modulation to Improve Glioma Drug Delivery

  2020cites this paper
• Prognostic Value of Dynamic Contrast-Enhanced MRI-Derived Pharmacokinetic Variables in Glioblastoma Patients: Analysis of Contrast-Enhancing Lesions and Non-Enhancing T2 High-Signal Intensity Lesions

  2020cites this paper
• Desmoid fibromatosis following surgical resection of spinal meningioma

  2020influential citation
• Multiparametric MRI for early identification of therapeutic response in recurrent glioblastoma treated with immune checkpoint inhibitors.

  2020cites this paper
• Applications of Quantitative Perfusion and Permeability in the Brain

  2020cites this paper
• Diffusion kurtosis imaging differs between primary central nervous system lymphoma and high-grade glioma and is correlated with the diverse nuclear-to-cytoplasmic ratio: a histopathologic, biopsy-based study

  2019cites this paper
• Evaluation of cortical bone perfusion using dynamic contrast enhanced ultrashort echo time imaging: a feasibility study.

  2019cites this paper
• Optimal acquisition scheme for flow‐compensated intravoxel incoherent motion diffusion‐weighted imaging in the abdomen: An accurate and precise clinically feasible protocol

  2019cites this paper
• Prognostic Predictions for Patients with Glioblastoma after Standard Treatment: Application of Contrast Leakage Information from DSC-MRI within Nonenhancing FLAIR High-Signal-Intensity Lesions

  2019cites this paper
• The Relationship Between Biological and Imaging Characteristics in Enhancing and Nonenhancing Glioma

  2019cites this paper
• Machine learning for semi-automated classification of glioblastoma, brain metastasis and central nervous system lymphoma using magnetic resonance advanced imaging.

  2019cites this paper
• Evaluation of tumor response to antiangiogenic therapy in patients with recurrent gliomas using contrast-enhanced perfusion-weighted magnetic resonance imaging techniques: A meta-analysis

  2019cites this paper
• “ Radiological Evaluation of Spectrum of Neurooncological Pathologies : Our Experience in a Tertiary Care Hospital of Eastern India ”

  2019cites this paper
• Applications and development of permeability imaging in ischemic stroke.

  2018cites this paper
• Intravenously-injected gold nanoparticles (AuNPs) access intracerebral F98 rat gliomas better than AuNPs infused directly into the tumor site by convection enhanced delivery

  2018cites this paper
• Dynamic MR imaging for functional vascularization depends on tissue factor signaling in glioblastoma

  2018cites this paper
• Differentiation between vasogenic edema and infiltrative tumor in patients with high‐grade gliomas using texture patch‐based analysis

  2018cites this paper
• Indirect MRI of 17o‐labeled water using steady‐state sequences: Signal simulation and preclinical experiment

  2018cites this paper
• Textural features of dynamic contrast‐enhanced MRI derived model‐free and model‐based parameter maps in glioma grading

  2018cites this paper
• Gd accumulation in tissues of healthy mice upon repeated administrations of Gadodiamide and Gadoteridol.

  2018cites this paper
• Histogram analysis of T2*-based pharmacokinetic imaging in cerebral glioma grading

  2018cites this paper
• Feasibility of multi-parametric PET and MRI for prediction of tumour recurrence in patients with glioblastoma

  2018cites this paper
• Repeatability of dynamic contrast enhanced vp parameter in healthy subjects and patients with brain tumors

  2018cites this paper
• Arginine Deprivation Therapy: Putative Strategy to Eradicate Glioblastoma Cells by Radiosensitization

  2017cites this paper
• Quantitative in vivo imaging of tissue factor expression in glioma using dynamic contrast-enhanced MRI derived parameters.

  2017cites this paper
• Measuring subtle leakage of the blood–brain barrier in cerebrovascular disease with DCE‐MRI: Test–retest reproducibility and its influencing factors

  2017cites this paper
• Current Clinical Brain Tumor Imaging

  2017cites this paper
• Dynamic contrast-enhanced MR imaging pharmacokinetic parameters as predictors of treatment response of brain metastases in patients with lung cancer

  2017cites this paper
• Contrast agents in dynamic contrast-enhanced magnetic resonance imaging

  2017cites this paper
• Rethinking cancer nanotheranostics.

  2017cites this paper
• Prognosis prediction of non-enhancing T2 high signal intensity lesions in glioblastoma patients after standard treatment: application of dynamic contrast-enhanced MR imaging

  2017cites this paper
• Clinical Applications of Contrast-Enhanced Perfusion MRI Techniques in Gliomas: Recent Advances and Current Challenges

  2017cites this paper
• Tracer Kinetic Models as Temporal Constraints during DCE-MRI reconstruction

  2017cites this paper
• Tracer kinetic models as temporal constraints during brain tumor DCE‐MRI reconstruction

  2017influential citation
• Neuro Dynamic Susceptibility Contrast MRI in Gliomas : What the Radiologist Needs to Know

  2016cites this paper
• A pilot study to determine the timing and effect of bevacizumab on vascular normalization of metastatic brain tumors in breast cancer

  2016cites this paper
• Assessment of DCE–MRI parameters for brain tumors through implementation of physiologically–based pharmacokinetic model approaches for Gd-DOTA

  2016cites this paper
• Perfusion Imaging in Neuro-Oncology: Basic Techniques and Clinical Applications.

  2016cites this paper
• Optimization of DCE-MRI protocol for the assessment of patients with brain tumors.

  2016cites this paper
• Measurement of subtle blood-brain barrier disruption in cerebral small vessel disease using dynamic contrast-enhanced magnetic resonance imaging

  2016cites this paper
• Integrative multimodal image analysis using physical models for characterization of brain tumors in radiotherapy

  2016cites this paper
• Addressing the Symptoms or Fixing the Problem? Developing Countermeasures against Normal Tissue Radiation Injury

  2016cites this paper
• Feasibility, phase I, and phase II studies of tandutinib, an oral platelet-derived growth factor receptor-&bgr; tyrosine kinase inhibitor, in patients with recurrent glioblastoma

  2016cites this paper
• Pretreatment Evaluation of Glioma.

  2016cites this paper
• Brain Vascular Imaging Techniques

  2016cites this paper
• Early changes in perfusion of glioblastoma during radio- and chemotherapy evaluated by T1-dynamic contrast enhanced magnetic resonance imaging

  2015cites this paper
• [Brain metastases imaging].

  2015cites this paper
• The Blood-Brain-Barrier in Brain Tumors

  2015cites this paper
• Magnetic resonance imaging biomarkers of cancer : with applications in high intensity focused ultrasound treatment evaluation

  2015cites this paper
• Background on Imaging Structural Imaging

  2015cites this paper
• Perfusion imaging in neuro-oncology: basic techniques and clinical applications.

  2015cites this paper
• Monitoring vascular normalization induced by antiangiogenic treatment with 18F‐fluoromisonidazole‐PET

  2015influential citation
• Quantitative multiparametric MRI in uveal melanoma: increased tumor permeability may predict monosomy 3

  2015cites this paper
• Bevacizumab Preconditioning Followed by Etoposide and Cisplatin Is Highly Effective in Treating Brain Metastases of Breast Cancer Progressing from Whole-Brain Radiotherapy

  2015cites this paper
• Human cerebral blood volume measurements using dynamic contrast enhancement in comparison to dynamic susceptibility contrast MRI

  2015cites this paper
• Functional imaging for radiotherapy treatment planning: current status and future directions—a review

  2015cites this paper
• The Impact of Flip Angle and TR on the Enhancement Ratio of Dynamic Gadobutrol-enhanced MR Imaging: In Vivo VX2 Tumor Model and Computer Simulation.

  2015cites this paper
• Effect of $$ T_{2}^{*} $$T2∗ correction on contrast kinetic model analysis using a reference tissue arterial input function at 7 T

  2015cites this paper
• Glioma grading by microvascular permeability parameters derived from dynamic contrast-enhanced MRI and intratumoral susceptibility signal on susceptibility weighted imaging

  2015influential citation
• A review of technical aspects of T1-weighted dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) in human brain tumors.

  2014cites this paper
• Multimodal magnetic resonance imaging evaluation of primary brain tumors.

  2014cites this paper
• Direct parametric reconstruction from undersampled (k, t)-space data in dynamic contrast enhanced MRI

  2014cites this paper
• Challenges in the design of clinically useful brain-targeted drug nanocarriers.

  2014cites this paper
• Assessment of blood–brain barrier disruption using dynamic contrast-enhanced MRI. A systematic review

  2014cites this paper
• Direct parametric reconstruction from undersampled (k, t)-space data in dynamic contrast enhancement MRI

  2013cites this paper
• High-Signal-Intensity Lesions FLAIR from DSC-MRI within Nonenhancing Application of Contrast Leakage Information Glioblastoma after Standard Treatment: Prognostic Predictions for Patients with

  year unknowncites this paper