Somatostatin and octreotide on the treatment of acute pancreatitis - basic and clinical studies for three decades.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Current pharmaceutical design

• Publication date

  2011-05-31

• Fields of study

  Medicine

• Identifiers
  DOI 10.2174/138161211796196936PMID 21548873
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2010cited by this paper
• Endoscopic treatment of acute biliary pancreatitis: A national survey among Dutch gastroenterologists

  2010cited by this paper
• Chronic Alcohol Intake Increases the Severity of Pancreatitis Induced by Acute Alcohol Administration, Hyperlipidemia and Pancreatic Duct Obstruction in Rats

  2010cited by this paper
• Decreased somatostatin is related to the hypersensitivity of intestinal epithelia to LPS via upregulated TLR4-TBK1 pathway in rats chronically exposed to ethanol.

  2009cited by this paper
• Alcohol Consumption and Development of Acute Respiratory Distress Syndrome: A Population-Based Study

  2009cited by this paper
• Somatostatin Limits Intestinal Ischemia-Reperfusion Injury in Macaques via Suppression of TLR4-NF-κB Cytokine Pathway

  2009cited by this paper
• Octreotide Attenuates Impaired Microcirculation in Postischemic Pancreatitis When Administered Before Induction of Ischemia

  2008cited by this paper
• Prophylactic Octreotide Administration Does Not Prevent Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis: A Meta-Analysis of Randomized Controlled Trials

  2008cited by this paper
• The role of NF-κB activation in the pathogenesis of acute pancreatitis

  2007cited by this paper
• Analysis of clinical features of acute pancreatitis in Shandong Province, China

  2007cited by this paper
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  2007cited by this paper
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  2006cited by this paper
• Obesity Is a Definitive Risk Factor of Severity and Mortality in Acute Pancreatitis: An Updated Meta-Analysis

  2006cited by this paper
• Trends in the Epidemiology of the First Attack of Acute Pancreatitis: A Systematic Review

  2006cited by this paper
• The Incidence and Case-fatality Rates of Acute Biliary, Alcoholic, and Idiopathic Pancreatitis in California, 1994-2001

  2006cited by this paper
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  2006cited by this paper
• Pancreatic Proteases in Serum Induce Leukocyte-Endothelial Adhesion and Pancreatic Microcirculatory Failure

  2005cited by this paper
• AMELIORATION OF THE DEVELOPMENT OF MULTIPLE ORGAN DYSFUNCTION SYNDROME BY SOMATOSTATIN VIA SUPPRESSION OF INTESTINAL MUCOSAL MAST CELLS

  2005cited by this paper
• Laboratory Markers of Severe Acute Pancreatitis

  2005cited by this paper
• Pancreatic Ischemia Associated With Vasospasm in the Early Phase of Human Acute Necrotizing Pancreatitis

  2005cited by this paper
• Obesity Increases the Severity of Acute Pancreatitis: Performance of APACHE-O Score and Correlation with the Inflammatory Response

  2005cited by this paper
• Compartmentalization of the Protease-antiprotease Balance in Early Severe Acute Pancreatitis

  2005cited by this paper
• Pathophysiology of Acute Pancreatitis

  2005cited by this paper
• Is the monocyte chemotactic protein-1 -2518 G allele a risk factor for severe acute pancreatitis?

  2005cited by this paper
• Apoptosis versus necrosis in acute pancreatitis.

  2004cited by this paper
• Effect of octreotide administration on serum interleukin-6 (IL-6) levels of patients with acute edematous pancreatitis.

  2004cited by this paper
• Signal Transduction, Calcium and Acute Pancreatitis

  2004cited by this paper
• Severe pancreatitis with exocrine destruction and increased islet neogenesis in mice with suppressor of cytokine signaling-1 deficiency.

  2004cited by this paper
• The Dynamics of the Oxidant-Antioxidant Balance in the Early Phase of Human Acute Biliary Pancreatitis

  2004cited by this paper
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  2004cited by this paper
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  2003cited by this paper
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  2003cited by this paper
• CC-chemokine activation in acute pancreatitis: enhanced release of monocyte chemoattractant protein-1 in patients with local and systemic complications

  2003cited by this paper
• Acute pancreatitis: Molecular biology update

  2003cited by this paper
• Adiposity Elevates Plasma MCP-1 Levels Leading to the Increased CD11b-positive Monocytes in Mice*

  2003cited by this paper
• The Impact of Intestinal Ischaemia-Reperfusion on Caerulein-Induced Oedematous Experimental Pancreatitis

  2003cited by this paper
• Dynamic nature of early organ dysfunction determines outcome in acute pancreatitis

  2002cited by this paper
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  2002cited by this paper
• NF-kappaB activation in pancreas induces pancreatic and systemic inflammatory response.

  2002cited by this paper
• Android Fat Distribution as Predictor of Severity in Acute Pancreatitis

  2002cited by this paper
• A Method Using Laser Doppler Flowmetry to Study Intestinal and Pancreatic Perfusion during an Acute Intestinal Ischaemic Injury in Rats with Pancreatitis

  2001cited by this paper
• Somatostatin and octreotide in acute pancreatitis: the never-ending story.

  2001cited by this paper
• From Acinar Cell Damage to Systemic Inflammatory Response: Current Concepts in Pancreatitis

  2001cited by this paper
• Chronic ethanol ingestion potentiates TNF-alpha-mediated oxidative stress and apoptosis in rat type II cells.

  2001cited by this paper
• Early Severe Acute Pancreatitis: Characteristics of a New Subgroup

  2001cited by this paper
• The significance of the dosage adjustment of octreotide in the treatment of acute pancreatitis of moderate severity.

  2001cited by this paper
• Octreotide Treatment in Patients with Severe Acute Pancreatitis

  2000cited by this paper
• Premature trypsinogen activation during cerulein pancreatitis in rats occurs inside pancreatic acinar cells.

  2000cited by this paper
• Role of cathepsin B in intracellular trypsinogen activation and the onset of acute pancreatitis.

  2000cited by this paper
• The effects of somatostatin and octreotide on experimental and human acute pancreatitis.

  2000cited by this paper
• Somatostatin through its specific receptor inhibits spontaneous and TNF-alpha- and bacteria-induced IL-8 and IL-1 beta secretion from intestinal epithelial cells.

  2000cited by this paper
• The effects of somatostatin and octreotide on the human sphincter of Oddi.

  1999cited by this paper
• Prevention by somatostatine and N-acetylcisteine of multiorgan failure mediated by oxidative stress after intestinal ischemia.

  1999cited by this paper
• Oxidative stress in acute pancreatitis.

  1999cited by this paper
• High dose octreotide in the management of acute pancreatitis.

  1999cited by this paper
• New Approaches to Acute Pancreatitis: Role of Inflammatory Mediators

  1999cited by this paper
• A randomised, double blind, multicentre trial of octreotide in moderate to severe acute pancreatitis

  1999cited by this paper
• Mechanism of increased lung injury after acute pancreatitis in IL-10 knockout mice.

  1998cited by this paper
• Obesity: A Risk Factor for Severe Acute Biliary and Alcoholic Pancreatitis

  1998cited by this paper
• Kupffer Cell Blockade Reduces Hepatic and Systemic Cytokine Levels and Lung Injury in Hemorrhagic Pancreatitis in Rats

  1998cited by this paper
• Severe acute pancreatitis: treatment with somatostatin

  1998cited by this paper
• Somatostatin Attenuates Microcirculatory Impairment in Acute Sodium Taurocholate-Induced Pancreatitis

  1998cited by this paper
• Premature trypsinogen activation during cerulein pancreatitis in rats occurs inside pancreatic acinar cells.

  1998cited by this paper
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  1997cited by this paper
• A randomized, controlled trial of octreotide in the management of patients with acute pancreatitis

  1997cited by this paper
• Octreotide treatment in patients with necrotizing pancreatitis and pulmonary failure

  1996cited by this paper
• Effects of delayed administration of octreotide in acute experimental pancreatitis.

  1996cited by this paper
• Preliminary report of a prospective randomized study of octreotide in the treatment of severe acute pancreatitis.

  1995cited by this paper
• Octreotide in the treatment of acute pancreatitis: results of a unicenter prospective trial with three different octreotide dosages.

  1994cited by this paper
• Influence of somatostatin in the evolution of acute pancreatitis

  1994cited by this paper
• Role of somatostatin and its analogues in the treatment of acute and chronic pancreatitis.

  1994cited by this paper
• Obesity: An important prognostic factor in acute pancreatitis

  1993cited by this paper
• Early treatment of acute biliary pancreatitis by endoscopic papillotomy.

  1993cited by this paper
• [The synthetic somatostatin analog octreotide: effect on interdigestive pancreas secretion and gastrointestinal motility in man].

  1993cited by this paper
• Controlled trial of high-dose octreotide in treatment of acute pancreatitis

  1993cited by this paper
• Somatostatin and somatostatin analogues--are they indicated in the management of acute pancreatitis?

  1993cited by this paper
• Effect of octreotide on sphincter of Oddi and gallbladder motility in prairie dogs.

  1992cited by this paper
• A double-blinded multicenter trial of somatostatin in the treatment of acute pancreatitis.

  1992cited by this paper
• Inhibition of human exocrine pancreatic secretion by the long‐acting somatostatin analogue octreotide (SMS 201‐995)

  1992cited by this paper
• Circulating tumor necrosis factor, interleukin‐1 and interleukin‐6 concentrations in chronic alcoholic patients

  1991cited by this paper
• Plasma endotoxin concentrations in patients with alcoholic and non-alcoholic liver disease: reevaluation with an improved chromogenic assay.

  1991cited by this paper
• Adverse Effect of Therapeutic Vasoconstrictors in Experimental Acute Pancreatitis

  1991cited by this paper
• Obesity as a predictor of severity in acute pancreatitis

  1991cited by this paper
• Increased Body Weight as a Prognostic Parameter for Complications in the Course of Acute Pancreatitis

  1990cited by this paper
• The use of somatostatin in acute pancreatitis--results of a multicenter trial.

  1990cited by this paper
• Somatostatin receptors on human lymphocytes and leukaemia cells.

  1990cited by this paper
• Somatostatin in the treatment of acute pancreatitis: a prospective randomised controlled trial.

  1989cited by this paper
• APACHE-II score for assessment and monitoring of acute pancreatitis.

  1989cited by this paper
• The effect of somatostatin analogue (SMS 201-995) on pancreatic blood flow.

  1988cited by this paper
• Microcirculatory effects of somatostatin in acute pancreatitis.

  1988cited by this paper
• Effect of somatostatin analogue (SMS 201-995, Sandostatin) on pancreatic secretion in humans.

  1987cited by this paper
• Interleukin‐3 modulation of mouse bone marrow derived mast cell receptors for somatostatin

  1987cited by this paper
• Endocrine profile of a long-acting somatostatin derivative SMS 201-995. Study in normal volunteers following subcutaneous administration.

  1986cited by this paper
• [Effect of somatostatin on hypercalcemia stimulated gastric juice and exocrine pancreas secretion in the human].

  1986cited by this paper
• Effects of a somatostatin analogue (SMS 201‐995) on hepatic and splenic reticulo‐endothelial function in the rat

  1985cited by this paper
• Determination of necrosis in necrotizing pancreatitis

  1985cited by this paper
• Prognostic factors in acute pancreatitis.

  1984cited by this paper
• A small dose of somatostatin inhibits the secretin stimulated secretion of bicarbonate, amylase, and chymotrypsin in man

  1980cited by this paper
• Treatment of acute pancreatitis with somatostatin.

  1980cited by this paper

• Understanding How Alcohol Induces Human Acute Alcoholic Pancreatitis

  2025cites this paper
• Combination of Somatostatin and Rectal Nonsteroidal Anti-Inflammatory Drugs for Prevention of Postendoscopic Retrograde Cholangiopancreatography Pancreatitis in High-Risk Patients: A Meta-Analysis of Randomized Controlled Trials.

  2024cites this paper
• Urinastatin combined with octreotide versus sole octreotide in severe acute pancreatitis: a meta-analysis

  2024cites this paper
• Remission of organ failure in patients with predicted severe acute pancreatitis treated by somatostation, octreotide and cyclooxygenase-2 inhibitors.

  2023cites this paper
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  2023cites this paper
• Beneficial effects of octreotide in alcohol-induced neuropathic pain. Role of H2S, BDNF, TNF-α and Nrf2

  2021cites this paper
• N-glycosylation of somatostatin receptor type 2 protects rats from acute pancreatitis

  2021cites this paper
• PPAR-Alpha Agonist Fenofibrate Combined with Octreotide Acetate in the Treatment of Acute Hyperlipidemia Pancreatitis

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• Current diagnosis and treatment of acute pancreatitis in China: a real-world, multicenter study

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• Effect of Adding Intravenous Somatostatin to Rectal Indomethacin on Post-Endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis in High-risk Patients

  2021cites this paper
• Octreotide alleviates pancreatic damage caused by paraquat in rats by reducing inflammatory responses and oxidative stress.

  2020cites this paper
• Carbachol protects the intestinal barrier in severe acute pancreatitis by regulating Cdc42/F-actin cytoskeleton

  2020cites this paper
• Prevention of Severe Acute Pancreatitis With Cyclooxygenase-2 Inhibitors: A Randomized Controlled Clinical Trial

  2020cites this paper
• The use of the synthetic analogue of leucin-encephaline in complementary therapy of dogs with chronic pancreatitis

  2020cites this paper
• Cyclooxygenase-2 up-regulates hepatic somatostatin receptor 2 expression

  2018cites this paper
• Pathogenesis and surgical treatment of posttraumatic pancreatitis in children

  2018cites this paper
• Effect of octreotide acetate combined with somatostatin on treating acute pancreatitis and expression of miRNA-200 family

  2017cites this paper
• Neuroprotective effects of octreotide on diabetic neuropathy in rats.

  2017cites this paper
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  2016cites this paper
• Acute Pancreatitis Due to Hypertriglyceridaemia in Pregnancy.

  2015cites this paper
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  2015cites this paper
• Acute Pancreatitis Due to Hypertriglyceridaemia in Pregnancy Gebelikte Hipertrigliseridemiye Bağli Akut Pankreatit

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• Drug Therapy for Acute

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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
• Pharmacologic therapy for acute pancreatitis.

  2014cites this paper
• Hepatocellular protein profiles after hepatic ischemia/reperfusion injury with or without octreotide preconditioning in a rabbit model.

  2014cites this paper
• Octreotide effects on the proliferation and apoptosis of hepatic stellate cells

  2013cites this paper
• Lanreotide autogel-induced acute pancreatitis in a patient with acromegaly.

  2013cites this paper
• High-dose versus low-dose octreotide in the treatment of acute pancreatitis: a randomized controlled trial.

  2013cites this paper
• The Effect of Somatostatin, Ulinastatin and Salvia miltiorrhiza on Severe Acute Pancreatitis Treatment

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  2013cites this paper
• СТРУКТУРНАЯ РЕОРГАНИЗАЦИЯ ОРГАНОВ ГЕПАТОПАНКРЕАТОДУОДЕНАЛЬНОЙ ЗОНЫ ПРИ ЖИРОВОМ И СМЕШАННОМ ПАНКРЕОНЕКРОЗЕ

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