Activation of immune function by dehydroepiandrosterone (DHEA) in age-advanced men.

No abstract is available for this paper.

• Publication year

  1997

• Venue

  The journals of gerontology. Series A, Biological sciences and medical sciences

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  DOI 10.1093/GERONA/52A.1.M1PMID 9008662
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Regulation of Insulin-Like Growth Factor Binding Protein-I During the 24-Hour Metabolic Clock and in Response to Hypoinsulinemia Induced by Fasting and Sandostatin in Normal Women

  1995cited by this paper
• Low serum levels of dehydroepiandrosterone may cause deficient IL‐2 production by lymphocytes in patients with systemic lupus erythematosus (SLE)

  1995cited by this paper
• Circadian characteristics of circulating interleukin-6 in men.

  1995cited by this paper
• A decreasing CD4+/CD8+ ratio after one month of treatment with stanazolol in postmenopausal women.

  1995cited by this paper
• An open study of dehydroepiandrosterone in systemic lupus erythematosus.

  1994cited by this paper
• Dehydroepiandrosterone (DHEA)--the "mother steroid". I. Immunologic action.

  1994cited by this paper
• Dehydroepiandrosterone (DHEA)--the multifunctional steroid. II. Effects on the CNS, cell proliferation, metabolic and vascular, clinical and other effects. Mechanism of action?

  1994cited by this paper
• Aging and immune function: Cellular and biochemical analyses

  1994cited by this paper
• Dehydroepiandrosterone (DHEA)‐the “Mother Steroid”

  1994cited by this paper
• Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age.

  1994cited by this paper
• Dehydroepiandrosterone (DHEA)–the Multifunctional Steroid

  1994cited by this paper
• The influence of an aging immune system on cancer incidence and progression.

  1993cited by this paper
• Reversal of the immunosenescent phenotype by dehydroepiandrosterone: hormone treatment provides an adjuvant effect on the immunization of aged mice with recombinant hepatitis B surface antigen.

  1993cited by this paper
• Altered regulation of IL-6 production with normal aging. Possible linkage to the age-associated decline in dehydroepiandrosterone and its sulfated derivative.

  1993cited by this paper
• Administration of dehydroepiandrosterone to burned mice preserves normal immunologic competence.

  1993cited by this paper
• Oral dehydroepiandrosterone in physiologic doses modulates immune function in postmenopausal women.

  1993influential reference
• An open-label dose-escalation trial of oral dehydroepiandrosterone tolerance and pharmacokinetics in patients with HIV disease.

  1993cited by this paper
• Interleukin-6 and aging: blood levels and mononuclear cell production increase with advancing age and in vitro production is modifiable by dietary restriction.

  1993cited by this paper
• Phase I study of recombinant human interleukin-2 for pediatric malignancies: feasibility of outpatient therapy. A Pediatric Oncology Group Study.

  1992cited by this paper
• Cellular and Molecular Immunology

  1992cited by this paper
• Physiological and molecular mechanisms of lymphocyte homing.

  1992cited by this paper
• The presence of a dehydroepiandrosterone-specific receptor binding complex in murine T cells.

  1992cited by this paper
• Circulating interleukin 6 as a useful marker for predicting postoperative complications.

  1992cited by this paper
• Aging and immune function.

  1991cited by this paper
• Current protocols in immunology

  1991cited by this paper
• Dehydroepiandrosterone antagonizes the suppressive effects of dexamethasone on lymphocyte proliferation.

  1991cited by this paper
• Dehydroepiandrosterone enhances IL2 production and cytotoxic effector function of human T cells.

  1991cited by this paper
• Generation of cytotoxic NK cells in peripheral blood and bone marrow of patients with acute myelogenous leukemia after continuous infusion with recombinant interleukin‐2

  1991cited by this paper
• Control of adrenal androgen secretion.

  1991cited by this paper
• Influence of age and caloric restriction on macrophage IL-6 and TNF production.

  1991cited by this paper
• Insulin-like growth factor-I binds selectively to human peripheral blood monocytes and B-lymphocytes.

  1991cited by this paper
• Inhibition of murine natural killer cell differentiation by dehydroepiandrosterone.

  1991cited by this paper
• DHEA AND THYMUS INTEGRITY IN THE MOUSE

  1990cited by this paper
• Regulation of murine lymphokine production in vivo. III. The lymphoid tissue microenvironment exerts regulatory influences over T helper cell function

  1990cited by this paper
• Protection from glucocorticoid induced thymic involution by dehydroepiandrosterone.

  1990cited by this paper
• Regulation of murine lymphokine production in vivo II. Dehydroepiandrosterone is a natural enhancer of interleukin 2 synthesis by helper T cells

  1990cited by this paper
• Peptide Growth Factors and Their Receptors I

  1990cited by this paper
• Hematologic and immunologic effects of the systemic administration of recombinant interleukin-2 after autologous bone marrow transplantation.

  1990cited by this paper
• Enhancement of human granulopoiesis in vitro by biosynthetic insulin-like growth factor I/somatomedin C and human growth hormone.

  1988cited by this paper
• Age-associated alterations in human natural killer cells. 2. Increased frequency of selective NK subsets.

  1988cited by this paper
• Protection against acute lethal viral infections with the native steroid dehydroepiandrosterone (DHEA)

  1988cited by this paper
• Age-associated alterations in human natural killer cells. 1. Increased activity as per conventional and kinetic analysis.

  1987cited by this paper
• Enhancement of the interleukin 2 receptor expression on T cells by multiple B-lymphotropic lymphokines.

  1987cited by this paper
• Serum levels of interleukin-6 and acute phase responses.

  1987cited by this paper
• Aging is without effect on the pituitary-adrenal axis in men.

  1986cited by this paper
• The expanded null cell compartment in ageing: increase in the number of natural killer cells and changes in T-cell and NK-cell subsets in human blood.

  1986cited by this paper
• Prevention of autoantibody formation and prolonged survival in New Zealand black/New Zealand white F1 mice fed dehydroisoandrosterone.

  1985cited by this paper
• Age changes and sex differences in serum dehydroepiandrosterone sulfate concentrations throughout adulthood.

  1984cited by this paper
• Immunological studies of aging. IX. Impaired proliferation of T lymphocytes detected in elderly humans by flow cytometry.

  1984cited by this paper
• Spontaneous or natural killer cytotoxicity of K562 erythroleukemic cells in normal patients.

  1981cited by this paper
• Dehydroepiandrosterone and 16 alpha-bromo-epiandrosterone: inhibitors of Epstein-Barr virus-induced transformation of human lymphocytes.

  1981cited by this paper
• A simple method for the assay of eight steroids in small volumes of plasma.

  1976cited by this paper

• The Role of Cortisol and Dehydroepiandrosterone in Obesity, Pain, and Aging

  2025cites this paper
• COMMON AND DISTINCT METABOLOMIC MARKERS RELATED TO IMMUNE AGING IN WESTERN EUROPEAN AND EAST AFRICAN POPULATIONS.

  2024cites this paper
• Natural killer cells immunosenescence and the impact of lifestyle management.

  2023cites this paper
• Age-related Changes in the Adrenal Cortex: Insights and Implications

  2023cites this paper
• Relationship between Serum Cortisol, Dehydroepiandrosterone Sulfate (DHEAS) Levels, and Natural Killer Cell Activity: A Cross-Sectional Study

  2023cites this paper
• The Timing Sequence and Mechanism of Aging in Endocrine Organs

  2023cites this paper
• Age, adrenal steroids, and cognitive functioning in captive chimpanzees (Pan troglodytes)

  2022cites this paper
• Associations between testosterone and immune activity in alligators depend on bacteria species and temperature

  2021influential citation
• Determinants of Serum Immunoglobulin Levels: A Systematic Review and Meta-Analysis

  2021cites this paper
• Tumor Microenvironment in Adrenocortical Carcinoma: Barrier to Immunotherapy Success?

  2021cites this paper
• Identification and Validation of Nutrient State-Dependent Serum Protein Mediators of Human CD4+ T Cell Responsiveness

  2021cites this paper
• Does dehydroepiandrosterone sulfate have a role in COVID-19 prognosis and treatment?

  2021cites this paper
• When wrinkles appear on the immune system can it be reversed?

  2020cites this paper
• Dehydroepiandrosterone (DHEA)

  2020cites this paper
• in an

  2020cites this paper
• An Electrochemical Biosensor Platform for Testing of Dehydroepiandrosterone 3‐Sulfate (DHEA−S) as a Model for Doping Materials

  2019cites this paper
• Exploring immunomodulation by endocrine changes in Lady Windermere syndrome

  2019cites this paper
• Reversal of epigenetic aging and immunosenescent trends in humans

  2019cites this paper
• Dehydroepiandrosterone Research: Past, Current, and Future.

  2018cites this paper
• Novel Risk Markers for Type 2 Diabetes : Inflammation, Body Fat and Sex Hormones

  2018influential citation
• DHEA Modulates Immune Function: A Review of Evidence.

  2018influential citation
• Dehydroepiandrosterone Administration as a Prophylaxis Against Acute Stress Reactivity in Military Personnel

  2018cites this paper
• Species specificity of an adrenal androgen-mediated kill-switch triggered by p53 inactivation

  2017cites this paper
• Essential Oil of Japanese Cedar (Cryptomeria japonica) Wood Increases Salivary Dehydroepiandrosterone Sulfate Levels after Monotonous Work

  2017cites this paper
• DHEA increases epithelial markers and decreases mesenchymal proteins in breast cancer cells and reduces xenograft growth

  2017cites this paper
• Consumption of green tea epigallocatechin-3-gallate enhances systemic immune response, antioxidative capacity and HPA axis functions in aged male swiss albino mice

  2017cites this paper
• Immunity, hormones, and life history trade-offs

  2017cites this paper
• Endocrine and Metabolic Pathways Linked to Keratoconus: Implications for the Role of Hormones in the Stromal Microenvironment

  2016cites this paper
• Dehydroepiandrosterone and its Sulfate Joint Statement by the German Society for Gynecological Endocrinology and Reproductive Medicine [DGGEF] and the German Professional Association of Gynecologists [BVF])

  2016cites this paper
• Serum dehydroepiandrosterone levels are associated with lower risk of type 2 diabetes: the Rotterdam Study

  2016cites this paper
• The Gonadotropins FSH and LH and their use in Adult Women – an Overview(Joint Statement by the German Society for Gynecological Endocrinology and Reproductive Medicine [DGGEF] and the German Professional Association of Gynecologists [BVF])

  2016cites this paper
• Dehydroepiandrosterone Supplementation Combined with Whole-Body Vibration Training Affects Testosterone Level and Body Composition in Mice

  2016cites this paper
• Chapter 105 – Adrenarche and Adrenopause

  2016cites this paper
• Adolescent-Onset Depression: Are Obesity and Inflammation Developmental Mechanisms or Outcomes?

  2015cites this paper
• Adolescent-Onset Depression: Are Obesity and Inflammation Developmental Mechanisms or Outcomes?

  2015cites this paper
• Androgens and innate immunity in rehabilitated semi‐captive orangutans (Pongo pygmaeus morio) from Malaysian Borneo

  2015cites this paper
• Improving leadership through the power of words and music

  2014cites this paper
• RESEARCH ARTICLE Environmental, Biological, and Social Factors Influencing Fecal Adrenal Steroid Concentrations in Female Japanese Macaques (Macaca Fuscata)

  2014cites this paper
• Environmental, biological, and social factors influencing fecal adrenal steroid concentrations in female Japanese macaques (Macaca fuscata)

  2014cites this paper
• Age- and gender-associated changes in the concentrations of serum TGF-1β, DHEA-S and IGF-1 in healthy captive baboons (Papio hamadryas anubis).

  2014cites this paper
• Serum metabolomics study of the acute graft rejection in human renal transplantation based on liquid chromatography-mass spectrometry.

  2014cites this paper
• Combination of dehydroepiandrosterone and orthovanadate administration reduces intestinal leukocyte recruitment in models of experimental sepsis.

  2014cites this paper
• Impact of physical activity on immune function and inflammation in the elderly

  2014cites this paper
• Effects of Psychosocial Stress on DHEA and DHEA-S levels Acute and Long-term effects

  2013cites this paper
• Die Rolle des Schlüsselhormons DHEA

  2013cites this paper
• Risk of Bronchopulmonary Dysplasia by Second Trimester Maternal Serum Levels of Alpha-fetoprotein, Human Chorionic Gonadotrophin, and Unconjugated Estriol

  2012cites this paper
• Sex steroids in Sjögren's syndrome.

  2012cites this paper
• Dehydroepiandrosterone-sulfate inhibits thrombin-induced platelet aggregation.

  2012cites this paper
• Cortisol and depression: three questions for psychiatry

  2012cites this paper
• Gender and Age in Lupus

  2011cites this paper
• Neuroendocrine effects of stress on immunity in the elderly: implications for inflammatory disease.

  2011cites this paper
• Dehydroepiandrosterone (DHEA)--a precursor steroid or an active hormone in human physiology.

  2011cites this paper
• DHEA, important source of sex steroids in men and even more in women.

  2010cites this paper
• Dehydroepiandrosterone as a regulator of immune cell function.

  2010cites this paper
• Effects of IM28 on HIV-1 and Metabolic Disorders-induced Highly Active Antiretroviral Therapy in Gabonese Patients

  2010cites this paper
• Effects of a Cognitive Behavioral Stress Management Intervention on the Psychological, Endocrinological, and Immunological Health of Minority Women Co-infected with HIV and HPV

  2010cites this paper
• Dehydroepiandrosterone (DHEA): a steroid with multiple effects. Is there any possible option in the treatment of critical illness?

  2010cites this paper
• Cortisol, DHEA sulphate, their ratio, and all-cause and cause-specific mortality in the Vietnam Experience Study.

  2010cites this paper
• Effect of dehydroepiandrosterone (DHEA) on monoamine oxidase activity, lipid peroxidation and lipofuscin accumulation in aging rat brain regions

  2008cites this paper
• Hormonal Supplements Legal and Illegal

  2008cites this paper
• The Effects of Age and Gender on Gingival Tissue and Peripheral Blood T-Lymphocyte Subsets: A Study in Mice

  2008cites this paper
• Fetal Adrenal Gland Volume and Cortisol/Dehydroepiandrosterone Sulfate Ratio in Inflammation-Associated Preterm Birth

  2008cites this paper
• Hormonas antienvejecimiento: melatonina y deshidroepiandrosterona

  2008cites this paper
• Dehydroepiandrosterone (DHEA) Effects on HIV Replication and Host Immunity: A Randomized Placebo-Controlled Study

  2007cites this paper
• The Dehydroepiandrosterone And WellNess (DAWN) study: research design and methods.

  2007cites this paper
• The analysis of dehydroepiandrosterone sulphate concentration in elderly age women depending on coexisting disease states.

  2007cites this paper
• Altered Cortisol/DHEA Ratio in Tuberculosis Patients and its Relationship with Abnormalities in the Mycobacterial‐driven Cytokine Production by Peripheral Blood Mononuclear Cells

  2007cites this paper
• Dehydroepiandrosterone (DHEA) Effects on HIV Replication and Host Immunity: A Randomized Placebo-Controlled Study

  2007cites this paper
• Colds and influenza: a review of diagnosis and conventional, botanical, and nutritional considerations.

  2007cites this paper
• Androgen Status of the Nonautoimmune Dry Eye Subtypes

  2006cites this paper
• Aging and the intestine.

  2006cites this paper
• Endocrine effects of oral dehydroepiandrosterone in men with HIV infection: a prospective, randomized, double-blind, placebo-controlled trial.

  2006cites this paper
• Consensus Document on substitution therapy with DHEA in the elderly

  2006cites this paper
• Differential effect of DHEA on mitogen-induced proliferation of T and B lymphocytes.

  2006cites this paper
• High interleukin‐10 production is associated with low antibody response to influenza vaccination in the elderly

  2006cites this paper
• Age‐related decline in RACK‐1 expression in human leukocytes is correlated to plasma levels of dehydroepiandrosterone

  2005cites this paper
• Beneficial Effects & Side Effects of DHEA: True Anti-Aging & Age-Promoting Effects, as well as Anti-Cancer & Cancer-Promoting Effects of DHEA Evaluated From the Effects on the Normal & Cancer Cell Telomeres & Other Parameters

  2005cites this paper
• Raised cortisol:DHEAS ratios in the elderly after injury: potential impact upon neutrophil function and immunity

  2005cites this paper
• Dehydroepiandrosterone treatment in the aging male--what should the urologist know?

  2005cites this paper
• Defect of a subpopulation of natural killer immune cells in Graves' disease and Hashimoto's thyroiditis: normalizing effect of dehydroepiandrosterone sulfate.

  2005cites this paper
• C(19)-5-ene steroids in nature.

  2005cites this paper
• Dehydroepiandrosterone replacement in patients with Addison's disease has a bimodal effect on regulatory (CD4+CD25hi and CD4+FoxP3+) T cells

  2005cites this paper
• Effects of Age and Immune Dysfunction on the Cardiac Extracellular Matrix and Diastolic Function

  2005cites this paper
• Dendritic cells and veiled accessory macrophages : hormonal influences and autoimmune thyroid disease

  2005cites this paper
• Modulation der Glucocorticoidwirkung durch Vitamin B6 und Dehydroepiandrosteron (DHEA) in menschlichen Immunzellen

  2005cites this paper
• Beneficial effects and side effects of DHEA: true anti-aging and age-promoting effects, as well as anti-cancer and cancer-promoting effects of DHEA evaluated from the effects on the normal and cancer cell telomeres and other parameters.

  2005cites this paper
• Abuse of anabolic androgenic steroids and related substances in sport and exercise.

  2004cites this paper
• Effect of DHEA on abdominal fat and insulin action in elderly women and men: a randomized controlled trial.

  2004cites this paper
• Dehydroepiandrosterone induces apoptosis of thymocyte through Fas/Fas-L pathway.

  2004cites this paper
• Stress responses and innate immunity: aging as a contributory factor

  2004cites this paper
• Dehydroepiandrosterone increases hippocampal spine synapse density in ovariectomized female rats.

  2004cites this paper
• Decreased Release of the Angiogenic Peptide Vascular Endothelial Growth Factor in Alzheimer’s Disease: Recovering Effect with Insulin and DHEA Sulfate

  2004cites this paper
• Impact of DHEA on GABA-agonist Challenge in Healthy Young and Older adults

  2003cites this paper
• Ingestion of a Dietary Supplement Containing Dehydroepiandrosterone (DHEA) and Androstenedione Has Minimal Effect on Immune Function in Middle-Aged Men

  2003cites this paper
• American Association of Clinical Endocrinologists medical guidelines for the clinical use of dietary supplements and nutraceuticals.

  2003cites this paper
• Long-Term Administration of Intravaginal Dehydroepiandrosterone on Regression of Low-Grade Cervical Dysplasia – A Pilot Study

  2003cites this paper
• Androgens and coronary artery disease.

  2003cites this paper
• Adrenocortical hormones in survivors and nonsurvivors of severe sepsis: Diverse time course of dehydroepiandrosterone, dehydroepiandrosterone-sulfate, and cortisol

  2003cites this paper
• Dehydroepiandrosterone: is there a role for replacement?

  2003cites this paper
• Association of DHEA-S and estradiol serum levels to symptoms of aging men

  2002cites this paper