Titanium Particles Stimulate Bone Resorption by Inducing Differentiation of Murine Osteoclasts

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Journal of Bone and Joint Surgery. American volume

• Publication date

  2001-04-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.2106/00004623-200104000-00004PMID 11315778
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Rapid repair of titanium particle‐induced osteolysis is dramatically reduced in aged mice

  2001cited by this paper
• Osteoblasts/stromal cells stimulate osteoclast activation through expression of osteoclast differentiation factor/RANKL but not macrophage colony-stimulating factor: receptor activator of NF-kappa B ligand.

  1999cited by this paper
• The effect of ultra-high molecular weight polyethylene wear debris on MG63 osteosarcoma cells in vitro.

  1999cited by this paper
• Bone marrow cells produce soluble factors that inhibit osteoclast activity

  1999cited by this paper
• Regulation of osteoclast activity.

  1999cited by this paper
• Measurement and removal of adherent endotoxin from titanium particles and implant surfaces

  1999cited by this paper
• Joint fluid from patients with failed total hip arthroplasty stimulates pit formation by mouse osteoclasts on dentin slices.

  1998cited by this paper
• Interleukin‐10 inhibits cytokine synthesis in monocytes stimulated by titanium particles: Evidence of an anti‐inflammatory regulatory pathway

  1998cited by this paper
• Corrosion of metal orthopaedic implants.

  1998cited by this paper
• Osteoclast Differentiation Requires Ascorbic Acid

  1998cited by this paper
• Isolation and characterization of osteoclast precursors that differentiate into osteoclasts on calvarial cells within a short period of time

  1998cited by this paper
• Oligoclonal T-cell proliferation and interferon-gamma production in periprosthetic inflammation.

  1998cited by this paper
• Number of polyethylene particles and osteolysis in total joint replacements. A quantitative study using a tissue-digestion method.

  1997cited by this paper
• Suppression of Osteoblast Function by Titanium Particles*†

  1997cited by this paper
• The effects of particulate cobalt, chromium and cobalt-chromium alloy on human osteoblast-like cells in vitro.

  1997cited by this paper
• Human arthroplasty derived macrophages differentiate into osteoclastic bone resorbing cells

  1997cited by this paper
• Radio-opaque agents in bone cement increase bone resorption.

  1997cited by this paper
• Tissue ingrowth and differentiation in the bone-harvest chamber in the presence of cobalt-chromium-alloy and high-density-polyethylene particles.

  1996cited by this paper
• Increased osteoclastic differentiation by PMMA particle-associated macrophages. Inhibitory effect by interleukin 4 and leukemia inhibitory factor.

  1996cited by this paper
• Granular Histiocytosis of Pelvic Lymph Nodes following Total Hip Arthroplasty. The Presence of Wear Debris, Cytokine Production, and Immunologically Activated Macrophages*

  1996cited by this paper
• Increased Levels of Tumor Necrosis Factor-&agr; and Interleukin-6 Protein and Messenger RNA in Human Peripheral Blood Monocytes due to Titanium Particles*

  1996cited by this paper
• In Vitro Studies on the Role of Titanium in Aseptic Loosening

  1996cited by this paper
• Activation of osteoclast-mediated bone resorption by the supernatant from a rabbit synovial cell line in response to polyethylene particles.

  1996cited by this paper
• Bone formation and bone resorption in failed total joint arthroplasties: Histomorphometric analysis with histochemical and immunohistochemical technique

  1996cited by this paper
• Human Macrophage Response to Retrieved Titanium Alloy Particles In Vitro

  1996cited by this paper
• Role of tumor necrosis factor alpha in particulate‐induced bone resorption

  1996cited by this paper
• Macrophage colony-stimulating factor and interleukin-1 alpha maintain the survival of osteoclast-like cells.

  1995cited by this paper
• Interleukin-4 induces foreign body giant cells from human monocytes/macrophages. Differential lymphokine regulation of macrophage fusion leads to morphological variants of multinucleated giant cells.

  1995cited by this paper
• Human monocyte response to particulate biomaterials generated in vivo and in vitro

  1995cited by this paper
• Isolation and characterization of debris in membranes around total joint prostheses.

  1995cited by this paper
• Isolation and characterization of highly enriched, prefusion mouse osteoclastic cells.

  1995cited by this paper
• Tissue ingrowth and differentiation in the bone-harvest chamber in the presence of cobalt-chromium-alloy and high-density-polyethylene particles.

  1995cited by this paper
• Isolation and characterization of debris in membranes around total joint prostheses.

  1994cited by this paper
• Response of three murine macrophage populations to particulate debris: Bone resorption in organ cultures

  1994cited by this paper
• Current concepts in orthopaedic biomaterials and implant fixation.

  1994cited by this paper
• Macrophages stimulate bone resorption when they phagocytose particles.

  1990cited by this paper
• Revision of residual deformities after operations for duplication of the thumb.

  1990cited by this paper
• Polymethylmethacrylate-induced release of bone-resorbing factors.

  1989cited by this paper
• The bone marrow-derived stromal cell lines MC3T3-G2/PA6 and ST2 support osteoclast-like cell differentiation in cocultures with mouse spleen cells.

  1989cited by this paper

• Surface modification of the laser powder bed-fused Ti-Zr-Nb scaffolds by dynamic chemical etching and Ag nanoparticles decoration.

  2024cites this paper
• Integrin β2 regulates titanium particle‑induced inflammation in macrophages: In vitro aseptic loosening model

  2024cites this paper
• Emerging factors affecting peri-implant bone metabolism.

  2023cites this paper
• Study on the effect of dynamic chemical polishing treatment on porous titanium alloy scaffolds fabricated using laser powder bed fusion

  2023cites this paper
• Influence of Noble Metals on the Microstructure and Properties of Biodegradable Mg-Nd-Zr Alloy

  2023cites this paper
• MiR-148a deletion protects from bone loss in physiological and estrogen-deficient mice by targeting NRP1

  2022cites this paper
• Diagnostic tests for titanium hypersensitivity in implant dentistry: a systematic review of the literature

  2022cites this paper
• Plasma electrolytic oxidation as an effective tool for production of copper incorporated bacteriostatic coatings on Ti-15Mo alloy

  2021cites this paper
• Melatonin suppresses Ti-particle-induced inflammatory osteolysis via activation of the Nrf2/Catalase signaling pathway.

  2020cites this paper
• Surface and morphological modification of selectively laser melted titanium lattices using a chemical post treatment

  2020cites this paper
• Elucidating the corrosion-related degradation mechanisms of a Ti-6Al-4V dental implant.

  2020cites this paper
• Blood Metal Ion Release After Primary Total Knee Arthroplasty: A Prospective Study

  2020cites this paper
• Biological Performance of a Bioabsorbable Magnesium–Magnesium Phosphate Cement Interbody Fusion Cage in a Porcine Lumbar Interbody Fusion Model: a Feasibility Study

  2020cites this paper
• In-vitro evaluation of novel titania-containing borate bioactive glass scaffolds.

  2020cites this paper
• In Vitro Cytotoxicity of Possible Corrosion Products from Mg-Based Biodegradable Metals: Magnesium Oxide and Magnesium Hydroxide Nanoparticles

  2019cites this paper
• Screw Track Osteolysis in the Cementless Total Knee Replacement Design.

  2019cites this paper
• Effects of staphylococcal infection and aseptic inflammation on bone mass and biomechanical properties in a rabbit model

  2019cites this paper
• A Review of Metal Exposure and Its Effects on Bone Health

  2018cites this paper
• Wear particles enhance autophagy through up-regulation of CD147 to promote osteoclastogenesis

  2018cites this paper
• In vitro and in vivo evaluation of PEO-modified titanium for bone implant applications

  2018cites this paper
• Pro-inflammatory Analysis of Macrophages in Contact with Titanium Particles and Porphyromonas gingivalis.

  2017cites this paper
• A laser-aided direct metal tooling technology for artificial joint surface coating

  2017cites this paper
• Direct influence of titanium and zirconia particles on the morphology and functionality of mature human osteoclasts.

  2017cites this paper
• A laser-aided direct metal tooling technology for artificial joint surface coating

  2017cites this paper
• Mg and Its Alloys for Biomedical Applications: Exploring Corrosion and Its Interplay with Mechanical Failure

  2017cites this paper
• Apoptotic pathways of macrophages within osteolytic interface membrane in periprosthestic osteolysis after total hip replacement

  2017cites this paper
• 11R-VIVIT Peptide Inhibits Calvaria Osteolysis Induced by Experimental Design

  2017cites this paper
• Progranulin suppresses titanium particle induced inflammatory osteolysis by targeting TNFα signaling

  2016cites this paper
• Release of titanium ions from an implant surface and their effect on cytokine production related to alveolar bone resorption.

  2015cites this paper
• Flow cytometry as a diagnostic tool for identifying total hip arthroplasty loosening and differentiating between septic and aseptic cases

  2015cites this paper
• Hypersensitivity Reactions to Titanium: Diagnosis and Management

  2015cites this paper
• TNF-α Suppression and Osteoprotegerin Overexpression Inhibits wear Debris-Induced Inflammation and Osteoclastogenesis in vitro

  2015cites this paper
• Effects of thirty elements on bone metabolism.

  2015cites this paper
• Comparison of high‐intensity sound and mechanical vibration for cleaning porous titanium cylinders fabricated using selective laser melting

  2015cites this paper
• Electromagnetically controllable osteoclast activity.

  2014cites this paper
• Review of models for titanium as a foreign body.

  2014cites this paper
• Controlled‐release of bone morphogenetic protein‐2 from a microsphere coating applied to acid‐etched Ti6AL4V implants increases biological bone growth in vivo

  2014cites this paper
• Corrosion Protection and Surface Treatment of Magnesium Alloys Used for Orthopedic Applications

  2013cites this paper
• Nano-crystalline diamond-coated titanium dental implants - a histomorphometric study in adult domestic pigs.

  2013cites this paper
• Influence of titanium on in vitro fibroblast-Porphyromonas gingivalis interaction in peri-implantitis.

  2013cites this paper
• In Vitro Corrosion and Cytocompatibility of ZK60 Magnesium Alloy Coated with Hydroxyapatite by a Simple Chemical Conversion Process for Orthopedic Applications

  2013cites this paper
• Osteoclasts Lose Innate Inflammatory Reactivity to Metal and Polymer Implant Debris Compared to Monocytes/Macrophages

  2013cites this paper
• Host-bacterial interaction in peri-implantitis

  2013cites this paper
• Bone formation controlled by biologically relevant inorganic ions: role and controlled delivery from phosphate-based glasses.

  2013cites this paper
• Review on magnesium alloys as biodegradable implant materials

  2012cites this paper
• Inhibitory effects of luteolin on titanium particle-induced osteolysis in a mouse model.

  2012cites this paper
• Assessment of Biodegradable Magnesium Alloys for Enhanced Mechanical and Biocompatible Properties

  2012cites this paper
• Toll-like receptors and macrophage polarization in the loosening of total hip replacements

  2012cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
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  2011cites this paper
• Impactability and time-dependent mechanical properties of porous titanium particles for application in impaction grafting.

  2010cites this paper
• Titanium ion induces necrosis and sensitivity to lipopolysaccharide in gingival epithelial-like cells.

  2010influential citation
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  2010cites this paper
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  2010cites this paper
• Biocorrosion and uptake of titanium by human osteoclasts.

  2010cites this paper
• Simulation of tissue differentiation in uncemented hip implants based on a mechanoregulatory hypothesis

  2010cites this paper
• Promotion of bone formation by naringin in a titanium particle‐induced diabetic murine calvarial osteolysis model

  2010cites this paper
• Effect of titanium particles on osteoclast activity in vitro.

  2010cites this paper
• Effects of screw eccentricity on the initial stability of the acetabular cup in artificial foam bone of different qualities.

  2010cites this paper
• Could insertion of the particles that induce osteolysis be a new treatment option in heterotopic ossification?

  2009cites this paper
• Orthopaedic Wear Particle-Induced Activation of Macrophages

  2009cites this paper
• Bio‐corrosion of stainless steel by osteoclasts—in vitro evidence

  2009cites this paper
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  2009cites this paper
• The roles of monocytic heat shock protein 60 and Toll-like receptors in the regional inflammation response to wear debris particles.

  2009cites this paper
• Immune reactivity to metal implants

  2009cites this paper
• Efficacy of colistin‐impregnated beads to prevent multidrug‐resistant A. baumannii implant‐associated osteomyelitis

  2009cites this paper
• Titanium induced production of chemokines CCL17/TARC and CCL22/MDC in human osteoclasts and osteoblasts.

  2009cites this paper
• Titanium IV ions induced human osteoclast differentiation and enhanced bone resorption in vitro.

  2009cites this paper
• Metal is not inert: role of metal ions released by biocorrosion in aseptic loosening--current concepts.

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• PGE2 Signaling Through the EP4 Receptor on Fibroblasts Upregulates RANKL and Stimulates Osteolysis

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• Stimulation of macrophage TNFα production by orthopaedic wear particles requires activation of the ERK1/2/Egr‐1 and NF‐κB pathways but is independent of p38 and JNK

  2008influential citation
• Modulation of the cross-talk between macrophages and osteoblasts by titanium-based particles.

  2008cites this paper
• Ätiologie und Pathogenese der periprothetischen Osteolyse

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• Versagensursachen primärer Implantationen

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• Polymethylmethacrylate particles stimulate bone resorption of mature osteoclasts in vitro

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• Kinetics of polymethylmethacrylate particle‐induced inhibition of osteoprogenitor differentiation and proliferation

  2007cites this paper
• Comparison of the roles of IL-1, IL-6, and TNFalpha in cell culture and murine models of aseptic loosening.

  2007cites this paper
• In vivo effects of coating loaded and unloaded Ti implants with collagen, chondroitin sulfate, and hydroxyapatite in the sheep tibia

  2007cites this paper
• Effects of screw eccentricity on the initial stability of the acetabular cup

  2007cites this paper
• Severe bone defects and reduced mineralization caused by massive metallosis after total knee arthroplasty: histopathologic and bone morphometric findings

  2007cites this paper
• The balance between endotoxin accumulation and clearance during particle‐induced osteolysis in murine calvaria

  2007cites this paper
• Aseptic loosening, not only a question of wear: A review of different theories

  2006cites this paper
• The Central Role of Wear Debris in Periprosthetic Osteolysis

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• Involvement of complement receptor 3 (CR3) and scavenger receptor in macrophage responses to wear debris

  2006cites this paper
• Fast element mapping of titanium wear around implants of different surface structures.

  2006cites this paper
• Soft and hard tissue response to zirconium dioxide dental implants--a clinical study in man.

  2006cites this paper
• Magnesium and its alloys as orthopedic biomaterials: a review.

  2006cites this paper
• A novel processing route for the fabrication of porous magnesium biomaterials

  2005cites this paper
• Does endotoxin contribute to aseptic loosening of orthopedic implants?

  2005cites this paper
• Intraspinal metalloma resulting in late paraparesis

  2005cites this paper
• Polyethylene and titanium particles induce osteolysis by similar, lymphocyte‐independent, mechanisms

  2005cites this paper
• Complications During Removal of Titanium Implants as Compared with Steel Implants in Children

  2005cites this paper
• Human interleukin-1-induced murine osteoclastogenesis is dependent on RANKL, but independent of TNF-alpha.

  2004cites this paper
• The effectiveness of polyethylene versus titanium particles in inducing osteolysis in vivo

  2004cites this paper
• Thalidomide blocking of particle-induced TNFα release in vitro

  2003cites this paper
• Thalidomide blocking of particle-induced TNFalpha release in vitro.

  2003cites this paper
• Use of volumetric computerized tomography as a primary outcome measure to evaluate drug efficacy in the prevention of peri‐prosthetic osteolysis: A 1‐year clinical pilot of etanercept vs. placebo

  2003cites this paper
• Humeral nonunion associated with metallosis secondary to use of a titanium flexible humeral intramedullary nail: a case report.

  2002cites this paper