Effects of Loading Frequency on Mechanically Induced Bone Formation

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Journal of Bone and Mineral Research

• Publication date

  2001-05-01

• Fields of study

  Medicine, Materials Science, Engineering

• Identifiers
  DOI 10.1359/jbmr.2001.16.5.918PMID 11341337
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Viscoelastic response of the rat loading model: implications for studies of strain-adaptive bone formation.

  1999cited by this paper
• Strain amplification in the bone mechanosensory system

  1998cited by this paper
• Fluid shear-induced mechanical signaling in MC3T3-E1 osteoblasts requires cytoskeleton-integrin interactions.

  1998cited by this paper
• Fluid Shear Stress Increases Interleukin‐11 Expression in Human Osteoblast‐like Cells: Its Role in Osteoclast Induction

  1998cited by this paper
• Osteoblast cytoskeletal modulation in response to mechanical strain in vitro

  1998cited by this paper
• Three rules for bone adaptation to mechanical stimuli.

  1998cited by this paper
• Modification of the in vivo four-point loading model for studying mechanically induced bone adaptation.

  1998cited by this paper
• Fluid shear-induced mechanical signaling in MC3T3-E1 osteoblasts requires cytoskeleton-integrin interactions.

  1998cited by this paper
• Biochemical Pathway Mediating the Response of Bone Cells to Capacitive Coupling

  1998cited by this paper
• Differential effect of steady versus oscillating flow on bone cells.

  1998cited by this paper
• Strain magnitude related changes in whole bone architecture in growing rats.

  1997cited by this paper
• Induction of NO and prostaglandin E2 in osteoblasts by wall-shear stress but not mechanical strain.

  1997cited by this paper
• Induction of NO and prostaglandin E2 in osteoblasts by wall-shear stress but not mechanical strain.

  1997cited by this paper
• Activation of G proteins mediates flow-induced prostaglandin E2 production in osteoblasts.

  1997cited by this paper
• Fluid flow stimulates rapid and continuous release of nitric oxide in osteoblasts.

  1996cited by this paper
• Pulsating fluid flow increases prostaglandin production by cultured chicken osteocytes--a cytoskeleton-dependent process.

  1996cited by this paper
• Real‐Time Calcium Response of Cultured Bone Cells to Fluid Flow

  1995cited by this paper
• Promotion of bony ingrowth by frequency-specific, low-amplitude mechanical strain.

  1994influential reference
• A model for the excitation of osteocytes by mechanical loading-induced bone fluid shear stresses.

  1994cited by this paper
• Noninvasive loading of the rat ulna in vivo induces a strain-related modeling response uncomplicated by trauma or periostal pressure

  1994cited by this paper
• Mechanical loading thresholds for lamellar and woven bone formation

  1994cited by this paper
• Mechanotransduction in bone: do bone cells act as sensors of fluid flow?

  1994cited by this paper
• A comparative analysis of streaming potentials in vivo and in vitro

  1992cited by this paper
• Fluid shear stress as a mediator of osteoblast cyclic adenosine monophosphate production

  1990cited by this paper
• Electric fields stimulate DNA synthesis of mouse osteoblast‐like cells (MC3T3‐E1) by a mechanism involving calcium ions

  1989cited by this paper
• Regulation of bone mass by mechanical strain magnitude

  1985cited by this paper
• Capacitative pulsed electric stimulation of bone cells. Induction of cyclic-AMP changes and DNA synthesis.

  1984cited by this paper
• Biomechanics: Mechanical Properties of Living Tissues

  1981cited by this paper
• Adaptation

  1926cited by this paper

• Simulation of dynamic loading effect on material degradation of magnesium wire/polylactic acid composite in human body environment

  2026cites this paper
• A whole bone-lacunocanalicular network-osteocyte model examining bone adaptation to distinct loading parameters

  2025cites this paper
• A 50‐year perspective on the use and potential of artiodactyl calcanei in bone adaptation studies

  2025cites this paper
• Effects of resistance training on microcirculation of bone tissue and bone turnover markers in postmenopausal women with osteopenia or osteoporosis: A systematic review

  2025cites this paper
• Accelerometer-derived daily impact score is positively associated with bone strength accrual during adolescence.

  2025cites this paper
• Protective role of exercise and curcumin on regional BMD and oxidative stress induced by lead

  2025cites this paper
• Effects of resistance training on microcirculation of bone tissue and bone turnover markers in postmenopausal women with osteopenia or osteoporosis: A systematic review

  2025cites this paper
• Resistance and Aerobic Preconditioning Delays Unloading‐Induced Multisystemic Physiological Changes: The NEBULA Project

  2025cites this paper
• Non-coding RNAs mediate mechanical load-regulating bone metabolic homeostasis

  2025cites this paper
• Assessing loading rate in frequency domain by accelerometry

  2025cites this paper
• SIRT1 and exercise-induced bone metabolism: a regulatory nexus

  2025cites this paper
• 3D Osteocyte Networks under Pulsatile Unidirectional Fluid Flow Stimuli (PUFFS)

  2025cites this paper
• Toward a clear relationship between mechanical signals and bone adaptation

  2025cites this paper
• Establishing correlation between bone mineral apposition rate and physiological loading using machine learning regressor

  2025cites this paper
• Relating strain amplitude, strain threshold and bone formation rate to exogenous forcing frequency

  2024influential citation
• Functional adaptation of bone mechanical properties using a diffusive stimulus originated by dynamic loads in bone remodelling

  2024cites this paper
• Implant-supported prosthesis under progressive loading protocol stimulates alveolar bone growth in patients with severe alveolar bone atrophy. Retrospective case series

  2024cites this paper
• How to Suppress Mineral Loss and Stimulate Anabolism in Postmenopausal Bones with Appropriate Timing of Exercise and Nutrients

  2024cites this paper
• Mechanically strained osteocyte-derived exosomes contained miR-3110-5p and miR-3058-3p and promoted osteoblastic differentiation

  2024cites this paper
• A frequency-dependent model for bone remodeling using a micromorphic porous medium subjected to harmonic mechanical loading

  2024cites this paper
• Cortical and Trabecular Bone Modeling and Implications for Bone Functional Adaptation in the Mammalian Tibia

  2024cites this paper
• Temporal regulation of BMP2 growth factor signaling in response to mechanical loading is linked to cytoskeletal and focal adhesion remodeling

  2024influential citation
• Computer model of non-Newtonian canalicular fluid flow in lacunar–canalicular system of bone tissue

  2024cites this paper
• A novel quasi-static compression test set-up with micron order accuracy for small specimens

  2024cites this paper
• Extracellular Mechanical Stimuli Alters the Metastatic Progression of Prostate Cancer Cells within 3D Tissue Matrix

  2023cites this paper
• High-cycle fatigue testing on AM60 magnesium alloy samples for as-received and pre-corroded conditions in simulated body fluid

  2023cites this paper
• Breed and loading history influence in vivo skeletal strain patterns in pre-pubertal female chickens.

  2023cites this paper
• Frizzled‐9 triggers actin polymerization and activates mechano‐transducer YAP to rescue simulated microgravity‐induced osteoblast dysfunction

  2023cites this paper
• Effect of Mechanical Loading on Bone Regeneration in HA/β-TCP/SF Scaffolds Prepared by Low-Temperature 3D Printing In Vivo.

  2023cites this paper
• Methodological aspects of in vivo axial loading in rodents: a systematic review

  2023cites this paper
• (Trainings-)Methodische Empfehlungen eines körperlichen Trainings zur Verbesserung der Knochenfestigkeit

  2023cites this paper
• Frizzled-9 activates YAP to rescue simulated microgravity induced osteoblasts dysfunction

  2023cites this paper
• Using Finite Element Modeling in Bone Mechanoadaptation

  2023cites this paper
• Mechanostat parameters estimated from time-lapsed in vivo micro-computed tomography data of mechanically driven bone adaptation are logarithmically dependent on loading frequency

  2023cites this paper
• Low-Amplitude and High-Frequency Loading Influences Interstitial Fluid Flow in Osteogenesis Imperfecta Osteon

  2022cites this paper
• Prediction of cortical bone mineral apposition rate in response to loading using an adaptive neuro-fuzzy inference system

  2022cites this paper
• Effect of resistance exercise on bone health of old aged individuals: Review

  2022cites this paper
• Effect of stretch frequency on osteogenesis of periodontium during periodontal ligament distraction.

  2022cites this paper
• Effect of Tensile Frequency on the Osteogenic Differentiation of Periodontal Ligament Stem Cells

  2022cites this paper
• Exosomes from Microvascular Endothelial Cells under Mechanical Unloading Inhibit Osteogenic Differentiation via miR-92b-3p/ELK4 Axis

  2022cites this paper
• Controlled mechanical early loads improve bone quality and quantity around implants: An in vivo experimental study.

  2022cites this paper
• Inhibition of SIRT1 by miR-138-5p provides a mechanism for inhibiting osteoblast proliferation and promoting apoptosis under simulated microgravity.

  2022cites this paper
• Progress of Periosteal Osteogenesis: The Prospect of In Vivo Bioreactor

  2022cites this paper
• Patterns and processes in amphibious fish: biomechanics and neural control of fish terrestrial locomotion.

  2022cites this paper
• Manipulating load-induced fluid flow in vivo to promote bone adaptation.

  2022cites this paper
• Calcium and phosphorus supplemented diet increases bone volume after thirty days of high speed treadmill exercise in adult mice

  2022cites this paper
• Effects of in vivo fatigue-induced microdamage on local subchondral bone strains.

  2022cites this paper
• Effect of external mechanical stimuli on human bone: a narrative review

  2021cites this paper
• A Three-Dimensional Mechanical Loading Model of Human Osteocytes in Their Native Matrix

  2021cites this paper
• Osteocytes

  2021cites this paper
• Computational biomechanical modelling of the rabbit cranium during mastication

  2021cites this paper
• Stress peaks, stiffening and back-flow in bilayer poro-elastic metamaterials

  2021cites this paper
• Promoting adaptive bone formation to prevent stress fractures in military personnel

  2021cites this paper
• Effects of backhand stroke styles on bone mineral content and density in postmenopausal recreational tennis players: a cross-sectional pilot investigation

  2021cites this paper
• Fluid shear stress regulates osteoblast proliferation and apoptosis via the lncRNA TUG1/miR‐34a/FGFR1 axis

  2021cites this paper
• Impact of high-load resistance training on bone mineral density in osteoporosis and osteopenia: a meta-analysis

  2021cites this paper
• The effect of exercise intensity on bone in postmenopausal women (part 1): A systematic review.

  2021cites this paper
• Fluid shear stress-induced down-regulation of microRNA-140-5p promotes osteoblast proliferation by targeting VEGFA via the ERK5 pathway

  2021cites this paper
• Modeling of the Human Bone Environment: Mechanical Stimuli Guide Mesenchymal Stem Cell–Extracellular Matrix Interactions

  2021cites this paper
• Muscle-Bone Crosstalk in the Masticatory System: From Biomechanical to Molecular Interactions

  2021cites this paper
• Differential effect of frequency and duration of mechanical loading on fetal chick cartilage and bone development.

  2021cites this paper
• Mechano-Regulation of Trabecular Bone Adaptation Is Controlled by the Local in vivo Environment and Logarithmically Dependent on Loading Frequency

  2020cites this paper
• Chemical analysis and antibacterial activities of Calotropis procera and Clusia rosea leaves extracts

  2020cites this paper
• A modular design strategy to integrate mechanotransduction concepts in scaffold-based bone tissue engineering.

  2020cites this paper
• Targeted Achilles Tendon Training and Rehabilitation Using Personalized and Real-Time Multiscale Models of the Neuromusculoskeletal System

  2020cites this paper
• Effects of dynamic resistance exercise on bone mineral density in postmenopausal women: a systematic review and meta-analysis with special emphasis on exercise parameters

  2020cites this paper
• Calcium- and Phosphorus-Supplemented Diet Increases Bone Volume After Four Weeks of High-Speed Treadmill Exercise in Adult Mice

  2020cites this paper
• Prediction of Individual Knee Kinematics From an MRI Representation of the Articular Surfaces

  2020cites this paper
• The Influence of Progressive Static Load on the Ability of Dental Implants to Withstand Overloading Forces: An Experimental Study in Dogs.

  2020cites this paper
• Terrestrial acclimation and exercise lead to bone functional response in Polypterus senegalus pectoral fins

  2020cites this paper
• Mechano-regulation of bone adaptation is controlled by the local in vivo environment and logarithmically dependent on loading frequency

  2020cites this paper
• Osteocyte Mechanobiology in Aging and Disease

  2020cites this paper
• Bone Muscle Crosstalk in Spinal Cord Injuries: Pathophysiology and Implications for Patients’ Quality of Life

  2020cites this paper
• Cancellous Bone May Have a Greater Adaptive Strain Threshold Than Cortical Bone

  2020cites this paper
• The influence of musculoskeletal forces on the growth of the prenatal cortex in the ilium: a finite element study

  2020cites this paper
• Exosomes derived from cyclic mechanical stretch-exposed bone marrow mesenchymal stem cells inhibit RANKL-induced osteoclastogenesis through the NF-κB signaling pathway

  2020cites this paper
• High shear stress amplitude in combination with prolonged stimulus duration determine induction of osteoclast formation by hematopoietic progenitor cells

  2020cites this paper
• Exercise in the Prevention of Osteoporosis-Related Fractures

  2020cites this paper
• The effects of acute exercise on bone turnover markers in middle-aged and older adults: A systematic review.

  2020cites this paper
• Signalling molecule transport analysis in lacunar–canalicular system

  2020cites this paper
• Measurement and Evaluation of Bone Loading in Physical Activity: A Systematic Review

  2020cites this paper
• The effect of intermittent running on biomarkers of bone turnover

  2020cites this paper
• Bone Adaptation in Adult Women Is Related to Loading Dose: A 12‐Month Randomized Controlled Trial

  2020cites this paper
• Low magnitude high frequency vibrations expedite the osteogenesis of bone marrow stem cells on paper based 3D scaffolds

  2020cites this paper
• Bone: Functions, Structure and Physiology

  2020cites this paper
• Effects of dietary fatty acid content on humeral cartilage and bone structure in a mouse model of diet‐induced obesity

  2019cites this paper
• Applicability of Low-Intensity Vibrations as a Regulatory Factor on Stem and Progenitor Cell Populations.

  2019cites this paper
• Regional changes in indices of bone strength of upper and lower limbs in response to high-intensity impact loading or high-intensity resistance training.

  2019cites this paper
• Nutritional Support and Physical Modalities for People with Osteoporosis: Current Opinion

  2019cites this paper
• The Role of Exercise on Fracture Reduction and Bone Strengthening

  2019cites this paper
• Experimental proof that multivariate patterns among muscle attachments (entheses) can reflect repetitive muscle use

  2019cites this paper
• Mechanical impairment on alveolar bone graft: A literature review.

  2019cites this paper
• Canalicular fluid flow induced by loading waveforms: A comparative analysis.

  2019cites this paper
• Exercise stresses bone tissue via mechanical stimuli from gravitational impact forces and muscular

  2019cites this paper
• Bone biology

  2019cites this paper
• Murine Axial Compression Tibial Loading Model to Study Bone Mechanobiology: Implementing the Model and Reporting Results

  2019cites this paper
• The influence of antiresorptive bone medication on the effect of high-intensity resistance and impact training on osteoporotic fracture risk in postmenopausal women with low bone mass: protocol for the MEDEX-OP randomised controlled trial

  2019cites this paper
• Degradation behaviors of Mg alloy wires/PLA composite in the consistent and staged dynamic environments.

  2019cites this paper
• Biophysical Regulation of Stem Cell Osteogenic Lineage Commitment: A Role for the Cytoskeleton

  2019cites this paper
• Evaluation of the Osteogenic Potential of Different Scaffolds Embedded with Human Stem Cells Originated from Schneiderian Membrane: An In Vitro Study

  2019cites this paper