Selegiline reduces daytime sleepiness in patients with Parkinson's disease

M. Gallazzi,M. Mauri,M. Bianchi,G. Riboldazzi,Lucia Princiotta Cariddi,F. Carimati,V. Rebecchi,M. Versino

Published 2021 in Brain and Behavior

ABSTRACT

Excessive daytime sleepiness (EDS) affects a large percentage of Parkinson's disease (PD) patients, and it is enhanced by dopamine agonist drugs. Currently, there is no treatment of choice for EDS in PD. Our aim was to check the clinical impression that some patients who were given selegiline, a selective inhibitor of monoamine oxidase B, experienced an improvement in their daytime somnolence.

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