Hepatic alpha 1-adrenergic receptors show agonist-specific regulation by guanine nucleotides. Loss of nucleotide effect after adrenalectomy.

No abstract is available for this paper.

• Publication year

  1982

• Venue

  Journal of Biological Chemistry

• Publication date

  1982-10-10

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/s0021-9258(18)33801-8PMID 6288692
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Heat treatment mimics guanosine-5'-triphosphate effects on dopaminergic 3H-ligand binding to bovine caudate membranes.

  1982cited by this paper
• Agonist-promoted high affinity state of the beta-adrenergic receptor in human neutrophils: modulation by corticosteroids.

  1981cited by this paper
• Inhibition of adenylate cyclase by hormones and neurotransmitters.

  1981cited by this paper
• Hypothyroidism modulates beta adrenergic receptor adenylate cyclase interactions in rat reticulocytes.

  1981cited by this paper
• Alpha-adrenergic receptors in liver membranes: delineation with subtype selective radioligands.

  1981cited by this paper
• Evidence for high and low affinity alpha 2-receptors. Comparison of [3H]norepinephrine and [3H]phentolamine binding to human platelet membranes.

  1981cited by this paper
• Two distinct alpha1-adrenergic receptor sites in rat liver: differential binding of (--)-[3H]dihydroergocryptine. Effects of guanine nucleotides and proteolysis; implications for a two-site model of alpha-receptor regulation.

  1981cited by this paper
• Myocardial beta-adrenergic receptors from adrenalectomized rats: impaired formation of high-affinity agonist-receptor complexes.

  1981cited by this paper
• Muscarinic receptor binding in mouse brain: regulation by guanine nucleotides.

  1980cited by this paper
• Subclassification of two types of alpha-adrenergic binding sites in rat liver.

  1980cited by this paper
• The role of hormone receptors and GTP-regulatory proteins in membrane transduction

  1980cited by this paper
• Heterogeneity of radioligand binding to alpha-adrenergic receptors. Analysis of guanine nucleotide regulation of agonist binding in relation to receptor subtypes.

  1980cited by this paper
• Proteolysis of rat liver plasma membranes cancels the guanine nucleotide sensitivity of agonist binding to the alpha-adrenoceptor.

  1980cited by this paper
• Agonist versus antagonist binding to alpha-adrenergic receptors.

  1980cited by this paper
• A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.

  1980cited by this paper
• (3H)-vasopressin binding to isolated rat hepatocytes and liver membranes: regulation by GTP and relation to glycogen phosphorylase activation.

  1980cited by this paper
• Ligand: a versatile computerized approach for characterization of ligand-binding systems.

  1980cited by this paper
• The alpha-adrenergic mediated effect in rat liver. Correlation between [3H]-dihydroergocryptine binding to plasma membranes and glycogen phosphorylase activation in isolated hepatocytes.

  1980cited by this paper
• Agonist-promoted coupling of the beta-adrenergic receptor with the guanine nucleotide regulatory protein of the adenylate cyclase system.

  1980cited by this paper
• Loss of beta-adrenergic receptor-guanine nucleotide regulatory protein interactions accompanies decline in catecholamine responsiveness of adenylate cyclase in maturing rat erythrocytes.

  1980cited by this paper
• The regulation of cardiac alpha 1-adrenergic receptors by guanine nucleotides and by muscarinic cholinergic agonists.

  1980cited by this paper
• Agonist-specific effects of guanine nucleotides on alpha-adrenergic receptors in human platelets.

  1979cited by this paper
• Guanine nucleotides modulate muscarinic receptor binding in the heart.

  1979cited by this paper
• Alpha-adrenergic receptor subtypes: quantitative assessment by ligand binding.

  1979cited by this paper
• Evidence for two alpha-adrenergic binding sites in liver plasma membranes. Studies with [3H]epinephrine and [3H]dihydroergocryptine.

  1979cited by this paper
• Effects of adrenalectomy on hormone action on hepatic glucose metabolism. Reciprocal change in alpha- and beta-adrenergic activation of hepatic glycogen phosphorylase and calcium mobilization in adrenalectomized rats.

  1979cited by this paper
• Effect of guanine nucleotides on striatal dopamine receptors

  1978cited by this paper
• Guanyl nucleotide influences on 3H-ligand binding to alpha-noradrenergic receptors in calf brain membranes.

  1978cited by this paper
• The agonist-specific effect of magnesium ion on binding by beta-adrenergic receptors in S49 lymphoma cells. Interaction of GTP and magnesium in adenylate cyclase activation.

  1978cited by this paper
• Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme.

  1978cited by this paper
• Interaction of ligands with the opiate receptors of brain membranes: regulation by ions and nucleotides.

  1978cited by this paper
• Characterization with [3H] dihydroergocryptine of the alpha-adrenergic receptor of the hepatic plasma membrane. Comparison with the beta-adrenergic receptor in normal and adrenalectomized rats.

  1978cited by this paper
• Slowly reversible binding of catecholamine to a nucleotide-sensitive state of the beta-adrenergic receptor.

  1977cited by this paper
• GTP-binding proteins in membranes and the control of adenylate cyclase activity.

  1977cited by this paper
• An agonist-specific effect of guanine nucleotides on binding to the beta adrenergic receptor.

  1976cited by this paper
• beta-adrenergic receptors in rat liver: effects of adrenalectomy.

  1976cited by this paper
• The vasopressin-sensitive adenylate cyclase of the rat kidney. Effect of adrenalectomy and corticosteroids on hormonal receptor-enzyme coupling.

  1974cited by this paper
• Adenylate-cyclase activity of rat-liver plasma membranes. Hormonal stimulation and effect of adrenalectomy.

  1973cited by this paper
• The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. V. An obligatory role of guanylnucleotides in glucagon action.

  1971cited by this paper
• The glucagon-sensitive adenyl cyclase system in plasma membranes of rat liver. IV. Effects of guanylnucleotides on binding of 125I-glucagon.

  1971cited by this paper
• Isolation of an organ specific protein antigen from cell-surface membrane of rat liver.

  1968cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper

• The Role of Galphaz in Neuron Development and CNS Biology

  2011cites this paper
• Mechanism of activation and inactivation of Gq/phospholipase C-β signaling nodes.

  2011cites this paper
• Guanine Nucleotides Regulates Both Agonist and Antagonist Binding to Cod Brain α1‐Adrenoceptors

  2009cites this paper
• BRIEF REVIEWS Molecular Characterization of Adrenergic Receptors

  2005cites this paper
• The aortic alpha1-adrenergic receptor in familial amyloidotic polyneuropathy

  2005cites this paper
• Demonstration of Ri-type adenosine receptors in bovine myocardium by radioligand binding

  2004cites this paper
• Adrenal insufficiency in a patient with severe hypotension caused by bilateral adrenal hemorrhage.

  2002cites this paper
• A new member of α 1-adrenoceptor-coupled G α h (transglutaminase II) family in pig heart: purification and characterization

  1998cites this paper
• α‐Adrenergic inhibition of proliferation in HepG2 cells stably transfected with the α1B‐adrenergic receptor through a p42MAP kinase/p21Cip1/WAF1‐dependent pathway

  1998cites this paper
• A new member of alpha 1-adrenoceptor-coupled G alpha h (transglutaminase II) family in pig heart: purification and characterization.

  1998cites this paper
• Alpha-adrenergic inhibition of proliferation in HepG2 cells stably transfected with the alpha1B-adrenergic receptor through a p42MAPkinase/p21Cip1/WAF1-dependent pathway.

  1998cites this paper
• The alpha1B-adrenergic receptor subtype activates the phospholipase C signaling pathway in rat myometrium at parturition.

  1997cites this paper
• Transglutaminase II: a new class of GTP-binding protein with new biological functions.

  1997cites this paper
• History of phosphoinositide research.

  1996cites this paper
• Signal transduction: evolution of an idea.

  1995cites this paper
• Nobel Lecture. Signal transduction: evolution of an idea.

  1995cites this paper
• Evidence for regulated coupling of A1 adenosine receptors by phosphorylation in Zucker rats.

  1995cites this paper
• Transduction mechanism of motilin and motilides in rabbit duodenal smooth muscle.

  1995cites this paper
• Regulation of hepatocyte plasma membrane alpha 1-adrenergic receptors by 4 beta-phorbol 12-myristate 13-acetate.

  1995cites this paper
• Signaltransduktion: Die Entwicklung einer Idee (Nobel‐Vortrag)

  1995cites this paper
• Alterations in the stimulatory G protein of the rat liver after partial hepatectomy.

  1994cites this paper
• Interactions between Ca(2+)-mobilizing receptors and their G proteins in hepatocytes.

  1994cites this paper
• Rapid and reversible uncoupling of the hepatic alpha 1-adrenergic receptor and guanine-nucleotide-binding protein by phorbol 12,13-dibutyrate.

  1993cites this paper
• [The effect of temperature on the kinetics of the alpha 1-adrenergic reaction of rat vas deferens smooth muscles].

  1993cites this paper
• Further characterization of 5-HT- and 5-HT3 receptor agonists'-stimulated phosphoinositol phosphates accumulation.

  1993cites this paper
• Different calcium-mobilizing receptors share the same guanine nucleotide-binding protein pool in hepatocytes.

  1992cites this paper
• Biochemical correlates with myocardial aging.

  1992cites this paper
• Regulation of phospholipase C isozymes.

  1992cites this paper
• The role of GTP-binding proteins in signal transduction: from the sublimely simple to the conceptually complex.

  1992cites this paper
• Alpha-1 adrenergic receptor: binding and phosphoinositide breakdown in human myometrium.

  1991cites this paper
• Sympathetic activity: modulator of myocardial hypertrophy.

  1991cites this paper
• Second messengers derived from inositol lipids

  1991cites this paper
• Heparin and other polyanions uncouple alpha 1-adrenoceptors from G-proteins.

  1991cites this paper
• Inositol phosphate formation and its relationship to calcium signaling.

  1990cites this paper
• A novel guanine nucleotide-binding protein coupled to the alpha 1-adrenergic receptor. I. Identification by photolabeling or membrane and ternary complex preparation.

  1990cites this paper
• Studies on the pathogenesis of hypertension in Cushing's disease and acromegaly.

  1990cites this paper
• Signal Transduction in Proliferating Normal and Transformed Cells

  1990cites this paper
• Alpha 1-adrenergic stimulation of inositide hydrolysis in liver of senescent rats.

  1990cites this paper
• Possible interaction of alpha 1-adrenergic receptor with pertussis-toxin-sensitive guanine-nucleotide-binding regulatory proteins (G proteins) responsible for phospholipase C activation in rat liver plasma membranes.

  1990cites this paper
• Identification and structural characterization of alpha 1-adrenergic receptor subtypes.

  1990cites this paper
• The Adrenal Medulla

  1990cites this paper
• Endothelin receptor is coupled to phospholipase C via a pertussis toxin-insensitive guanine nucleotide-binding regulatory protein in vascular smooth muscle cells.

  1990cites this paper
• Effect of adrenalectomy on Ca2+ signaling in rat hepatocytes.

  1990cites this paper
• CHAPTER 18 – Phosphatidylinositol Phospholipase C

  1990cites this paper
• Effects of calcium channel blockers and hydralazine on plasma glucose levels in streptozotocin-induced diabetic rats in vivo.

  1990cites this paper
• CHAPTER 25 – GTP-Binding Proteins and Exocytotic Secretion

  1990cites this paper
• G protein-dependent regulation of phospholipase C by cell surface receptors.

  1990cites this paper
• Reduced high‐affinity α1‐adrenoceptors in liver of senescent rats: implications of assessment at various temperatures

  1990cites this paper
• The role of G proteins in transmembrane signalling.

  1990cites this paper
• Pertussis toxin inhibits norepinephrine-stimulated inositol phosphate formation in primary brain cell cultures.

  1990cites this paper
• Receptor-effector coupling by G proteins.

  1990cites this paper
• [Signal transduction mechanism of Ca2(+)-mobilizing hormone receptor and GTP binding proteins].

  1990cites this paper
• Reduced alpha 1-adrenergic receptor-mediated inositide hydrolysis in cardiac atria of senescent rats.

  1990cites this paper
• A novel guanine nucleotide-binding protein coupled to the alpha 1-adrenergic receptor. II. Purification, characterization, and reconstitution.

  1990cites this paper
• Possible interaction of α1-adrenergic receptor with pertussis-toxin-sensitive guanine-nucleotide-binding regulatory proteins (G proteins) responsible for phospholipase C activation in rat liver plasma membranes

  1990cites this paper
• Role of phosphoinositides in transmembrane signaling.

  1990cites this paper
• Role of Calcium on Excitation‐Contraction Coupling in Cardiac and Vascular Smooth Muscle

  1989cites this paper
• Molecular basis of regulation of ionic channels by G proteins.

  1989cites this paper
• Regulation of hepatocyte growth: Alpha‐1 adrenergic receptor and ras p21 changes in liver regeneration

  1989cites this paper
• Activation of Phosphoinositide-Specific Phospholipase C by Ligands in the Presence of Guanine Nucleotides

  1989cites this paper
• Kinetics of activation of phospholipase C by P2Y purinergic receptor agonists and guanine nucleotides.

  1989cites this paper
• Modification of AlF-4- and receptor-stimulated phospholipase C activity by G-protein beta gamma subunits.

  1989cites this paper
• Developmental Changes in Guanine Nucleotide Regulatory Proteins in the Rat Myocardial α1-Adrenergic Receptor Complex

  1989cites this paper
• The roles of calcium and phosphoinositides in the mechanisms of alpha 1-adrenergic and other agonists.

  1988cites this paper
• Coupling of the alpha 1-adrenergic receptor to a guanine nucleotide-binding regulatory protein by a discrete domain distinct from its ligand recognition site.

  1988cites this paper
• The effects of adrenalectomy on the alpha-adrenergic regulation of cytosolic free calcium in hepatocytes.

  1988cites this paper
• Complex interactions of agonists with α1‐adrenoceptors in intact cells

  1988cites this paper
• Complex interactions of agonists with alpha 1-adrenoceptors in intact cells.

  1988cites this paper
• The aortic alpha 1-adrenergic receptor in familial amyloidotic polyneuropathy.

  1988cites this paper
• The role of phosphoinositide metabolism in signal transduction in secretory cells.

  1988cites this paper
• Amine Transmitters and their Associated Second Messenger Systems

  1988cites this paper
• Alpha 1-adrenergic receptor subtypes, inositol phosphates, and sources of cell Ca2+.

  1988cites this paper
• Alpha adrenoceptor sites in vascular smooth muscle. Differentiation by selective antagonist binding.

  1988cites this paper
• G-proteins, the inositol lipid signalling pathway, and secretion.

  1988cites this paper
• Inositol Lipids, G-Proteins and Signal Transduction

  1988cites this paper
• Chapter 2 Inositol phospholipids and cellular signalling

  1988cites this paper
• Fluoride stimulates in vitro vascular prostacyclin synthesis: interrelationship of G proteins and protein kinase C.

  1988cites this paper
• Human neutrophil protein kinase C: calcium-induced changes in the solubility of the enzyme do not always correlate with enzymatic activity.

  1988cites this paper
• Alkylation of alpha-1 receptors with a chemically reactive analog of prazosin reveals low affinity sites for norepinephrine in rabbit aorta.

  1988cites this paper
• Cellular and Molecular Aspects of Inflammation

  1988cites this paper
• Role of inositol trisphosphate as a second messenger in signal transduction processes: An essay

  1988cites this paper
• The role of phosphoinositide metabolism in signal transduction in secretory cells.

  1988cites this paper
• Formation of the high‐affinity agonist state of the α1‐adrenergic receptor at cold temperatures does not require a G‐protein

  1988cites this paper
• Alpha-Adrenergic Receptors in Familial Amyloidotic Polyneuropathy

  1988cites this paper
• Regulation of alpha-2 Adrenergic Receptors

  1988cites this paper
• Regulation of Inositol Trisphosphate Formation and Action

  1988cites this paper
• Activation of the neutrophil.

  1988cites this paper
• GTP-binding proteins in the control of exocytosis.

  1988cites this paper
• Characteristics of [3H]nimodipine binding to sarcolemmal membranes from rat vas deferens and its regulation by guanine nucleotide.

  1988cites this paper
• Comparative Invertebrate Neurochemistry

  1988cites this paper
• Formation and actions of calcium-mobilizing messenger, inositol 1,4,5-trisphosphate.

  1987cites this paper
• Chapter 1 – Phosphoinositides and Calcium Signaling

  1987cites this paper
• Alpha 1-adrenergic receptor-linked guanine nucleotide-binding protein in muscle and kidney epithelial cells.

  1987cites this paper
• Time dependent conversion from alpha 1- to beta-adrenoceptor-mediated glycogenolysis in isolated rat hepatocytes: role of membrane phospholipase A2 and protein kinase C.

  1987cites this paper
• A pertussis toxin substrate regulates alpha 1-adrenergic dependent phosphatidylinositol hydrolysis in cultured rat myocytes.

  1987cites this paper
• Comparison of agonist-induced changes in beta- and alpha 1-adrenergic receptors of DDT1 MF-2 cells.

  1987cites this paper
• Turkey erythrocyte membranes as a model for regulation of phospholipase C by guanine nucleotides.

  1987cites this paper
• Chapter 2 – SIGNALLING SYSTEMS IN STIMULUS-RESPONSE COUPLING1

  1987cites this paper
• Phosphoinositides and alpha-1 Adrenergic Receptors

  1987cites this paper
• Biochemistry and Pharmacology of the alpha-1 Adrenergic Receptor

  1987cites this paper