Cell cycle-dependent strand bias for UV-induced mutations in the transcribed strand of excision repair-proficient human fibroblasts but not in repair-deficient cells

No abstract is available for this paper.

• Publication year

  1991

• Venue

  Molecular and Cellular Biology

• Publication date

  1991-04-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1128/mcb.11.4.1927-1934.1991PMID 2005888PMCID PMC359877
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Kinds and location of mutations induced by (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase gene in diploid human fibroblasts.

  1991cited by this paper
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  1990cited by this paper
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  1990cited by this paper
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  1989cited by this paper
• DNA strand specificity for UV-induced mutations in mammalian cells

  1989cited by this paper
• Amplification and direct nucleotide sequencing of cDNA from the lysate of low numbers of diploid human cells.

  1989cited by this paper
• Nonsense mutations in the dihydrofolate reductase gene affect RNA processing

  1989cited by this paper
• Coordinated leading and lagging strand synthesis during SV40 DNA replication in vitro requires PCNA.

  1988cited by this paper
• Yeast ARS function and nuclear matrix association coincide in a short sequence from the human HPRT locus

  1988cited by this paper
• Selective removal of transcription-blocking DNA damage from the transcribed strand of the mammalian DHFR gene.

  1987influential reference
• Sequence effect on alkali-sensitive sites in UV-irradiated SV40 DNA.

  1987cited by this paper
• The specificity of UV-induced mutations at an endogenous locus in mammalian cells.

  1987cited by this paper
• Mechanisms of ultraviolet-induced mutation. Mutational spectra in the Escherichia coli lacI gene for a wild-type and an excision-repair-deficient strain.

  1987cited by this paper
• Modification of MCDB 110 medium to support prolonged growth and consistent high cloning efficiency of diploid human fibroblasts.

  1987cited by this paper
• DNA sequence analysis of the mutational specificity of u.v. light in the SUP4-o gene of yeast.

  1987cited by this paper
• Sequence specificity of point mutations induced during passage of a UV-irradiated shuttle vector plasmid in monkey cells

  1986cited by this paper
• Preferential DNA repair of an active gene in human cells.

  1986cited by this paper
• Survival of UV-irradiated mammalian cells correlates with efficient DNA repair in an essential gene.

  1986cited by this paper
• The C-C (6-4) UV photoproduct is mutagenic in Escherichia coli.

  1986cited by this paper
• Excision repair of UV- or benzo[a]pyrene diol epoxide-induced lesions in xeroderma pigmentosum variant cells is 'error free'.

  1985influential reference
• (6-4)Photoproducts are removed from the DNA of UV-irradiated mammalian cells more efficiently than cyclobutane pyrimidine dimers.

  1985cited by this paper
• The frequency of mutants in human fibroblasts UV-irradiated at various times during S-phase suggests that genes for thioguanine- and diphtheria toxin-resistance are replicated early.

  1985cited by this paper
• XERODERMA PIGMENTOSUM FIBROBLASTS INCLUDING CELLS FROM XP VARIANTS ARE ABNORMALLY SENSITIVE TO THE MUTAGENIC AND CYTOTOXIC ACTION OF BROAD SPECTRUM SIMULATED SUNLIGHT

  1984cited by this paper
• Extent of excision repair before DNA synthesis determines the mutagenic but not the lethal effect of UV radiation.

  1982cited by this paper
• Induction of 6-thioguanine- and ouabain-resistant mutations in synchronized Syrian hamster cell cultures during different periods of the S phase.

  1978cited by this paper
• Typical xeroderma pigmentosum complementation group A fibroblasts have detectable ultraviolet light-induced unscheduled DNA synthesis.

  1977cited by this paper

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  2022cites this paper
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  2020cites this paper
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  2017cites this paper
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  2016cites this paper
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  2015cites this paper
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  2014cites this paper
• Characterisation of UVA-induced DNA damage responses in human skin cells

  2013cites this paper
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  2013cites this paper
• Wavelength-dependent ultraviolet induction of cyclobutane pyrimidine dimers in the human cornea

  2013cites this paper
• Solar-UV-signature mutation prefers TCG to CCG: extrapolative consideration from UVA1-induced mutation spectra in mouse skin

  2013cites this paper
• Transcription-associated genome instability.

  2013cites this paper
• Regulation of mutagenesis by exogenous biological factors in the eukaryotic cell systems

  2013cites this paper
• Réparation par excision de nucléotides spécifique au cycle cellulaire : implications pour la résistance à la chimiothérapie dans le cancer de l'ovaire humain

  2011cites this paper
• Genetic Instability and Tumorigenesis

  2011cites this paper
• Ultraviolet Light‐Induced Cyclobutane Pyrimidine Dimers in Rabbit Eyes

  2011cites this paper
• Transcription-dependent cytosine deamination is a novel mechanism in ultraviolet light-induced mutagenesis.

  2010cites this paper
• Site-specific analysis of UV-induced cyclobutane pyrimidine dimers in nucleotide excision repair-proficient and -deficient hamster cells: Lack of correlation with mutational spectra.

  2009cites this paper
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  2009cites this paper
• RAD18 signals DNA polymerase IOTA to stalled replication forks in cells entering S-phase with DNA damage.

  2008cites this paper
• Preneoplastic lesion growth driven by the death of adjacent normal stem cells

  2008cites this paper
• RAD18 and associated proteins are immobilized in nuclear foci in human cells entering S-phase with ultraviolet light-induced damage.

  2008cites this paper
• Cell-type-specific consequences of nucleotide excision repair deficiencies: Embryonic stem cells versus fibroblasts.

  2008cites this paper
• Mechanisms of mutation formation with long‐wave ultraviolet light (UVA)

  2008cites this paper
• Mutagenic and tumor suppressor functions of DNA polymerase iota in mammalian cells

  2008cites this paper
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  2007cites this paper
• Evidence that in xeroderma pigmentosum variant cells, which lack DNA polymerase eta, DNA polymerase iota causes the very high frequency and unique spectrum of UV-induced mutations.

  2007cites this paper
• Short- and long-wave UV light (UVB and UVA) induce similar mutations in human skin cells.

  2006cites this paper
• Participation of mouse DNA polymerase ι in strand-biased mutagenic bypass of UV photoproducts and suppression of skin cancer

  2006cites this paper
• Telomerase-immortalized human fibroblasts retain UV-induced mutagenesis and p53-mediated DNA damage responses.

  2006cites this paper
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  2006cites this paper
• Immunohistochemistry assessment of p53 protein in Basal cell carcinoma.

  2005cites this paper
• Transcription-coupled repair: impact on UV-induced mutagenesis in cultured rodent cells and mouse skin tumors.

  2005cites this paper
• Ultraviolet radiation and skin cancer: molecular mechanisms

  2005influential citation
• The regulation of a variability of somatic mammalian cell genome under the influence of exogeneous biological factors

  2004cites this paper
• Photocopying cancer cells.

  2003cites this paper
• Ribozyme-mediated REV1 inhibition reduces the frequency of UV-induced mutations in the human HPRT gene.

  2003cites this paper
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  2003cites this paper
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  2003cites this paper
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  2002cites this paper
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  2001cites this paper
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  2001cites this paper
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  2001cites this paper
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  2000cites this paper
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  2000cites this paper
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  2000cites this paper
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  2000cites this paper
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  2000cites this paper
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  2000cites this paper
• The yeast p53 functional assay: a new tool for molecular epidemiology. Hopes and facts.

  2000cites this paper
• Ultraviolet radiation mutagenesis of hedgehog pathway genes in basal cell carcinomas.

  1999cites this paper
• DNA repair, DNA replication, and UV mutagenesis.

  1999cites this paper
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  1999cites this paper
• DNA Damage and Mutations Induced by Solar UV Radiation

  1999cites this paper
• Mutation in mammalian cells in vitro and in vivo as indicators of exposure to carcinogens.

  1999cites this paper
• Abnormal, Error-Prone Bypass of Photoproducts by Xeroderma Pigmentosum Variant Cell Extracts Results in Extreme Strand Bias for the Kinds of Mutations Induced by UV Light

  1999cites this paper
• Mutations in cancer genes of UV-induced skin tumors of hairless mice.

  1999cites this paper
• Alterations of p53 gene and Ha‐ras gene are independent events in solar keratosis and squamous cell carcinoma

  1998cites this paper
• Mutagenesis of the p̳53 tumor suppressor gene studied in Saccharomyces cerevisiae

  1998cites this paper
• Strand specificity and absence of hot spots for p53 mutations in ultraviolet B-induced skin tumors of XPA-deficient mice.

  1998cites this paper
• Sequence and time-dependent deamination of cytosine bases in UVB-induced cyclobutane pyrimidine dimers in vivo.

  1998cites this paper
• The role of proliferation in the origin of mutations in mammalian cells.

  1998cites this paper
• A specific spectrum of p53 mutations in lung cancer from smokers: review of mutations compiled in the IARC p53 database.

  1998cites this paper
• Nucleotide Excision Repair

  1998cites this paper
• Correlation of UV-induced mutational spectra and the in vitro damage distribution at the human hprt gene.

  1998cites this paper
• Mutations that alter RNA splicing of the human HPRT gene: a review of the spectrum.

  1998cites this paper
• Ultraviolet-light induced p53 mutational spectrum in yeast is indistinguishable from p53 mutations in human skin cancer.

  1998cites this paper
• Transcription coupled repair and its impact on mutagenesis.

  1998cites this paper
• Effect of green tea on p53 mutation distribution in ultraviolet B radiation-induced mouse skin tumors.

  1998cites this paper
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  1998cites this paper
• Skin precancer.

  1998cites this paper
• p53 mutations in sweat gland carcinomas

  1998cites this paper
• Mutation spectra resulting from carcinogenic exposure: from model systems to cancer-related genes.

  1998cites this paper
• A human homolog of the Saccharomyces cerevisiae REV3 gene, which encodes the catalytic subunit of DNA polymerase zeta.

  1998cites this paper
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  1998cites this paper
• Photoprotective actions of vitamin E in mouse skin: Prevention of UVB-induced DNA photodamage

  1997cites this paper
• Somatic mutation theory, DNA repair rates, and the molecular epidemiology of p53 mutations.

  1997cites this paper
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  1997cites this paper
• Mutation frequency and spectrum in lymphocytes of small cell lung cancer patients receiving etoposide chemotherapy.

  1997cites this paper
• Characterization of SV40-transformed xeroderma pigmentosum cell lines for their usability in HPRT mutation studies.

  1997cites this paper
• Ultraviolet-induced photolesions: repair and mutagenesis.

  1997cites this paper
• Inducible nucleotide excision repair (NER) of UV-induced cyclobutane pyrimidine dimers in the cell cycle of the budding yeast Saccharomyces cerevisiae : evidence that inducible NER is confined to the G1 phase of the mitotic cell cycle

  1997cites this paper
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  1997cites this paper
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  1997cites this paper
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  1997cites this paper
• Formation and Processing of UV Photoproducts: Effects of DNA Sequence and Chromatin Environment

  1997cites this paper
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  1997cites this paper
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  1997cites this paper
• Mutational spectra: from model systems to cancer-related genes.

  1996cites this paper
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  1996cites this paper
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  1996cites this paper
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