Tissue factor: a link between C5a and neutrophil activation in antiphospholipid antibody induced fetal injury.

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Blood

• Publication date

  2007-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1182/BLOOD-2007-01-070631PMID 17536017PMCID PMC1988945
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Role of cardiac myocyte tissue factor in heart hemostasis

  2007cited by this paper
• Toll-like receptor and antiphospholipid mediated thrombosis: in vivo studies

  2007cited by this paper
• Tissue factor deficiency and PAR-1 deficiency are protective against renal ischemia reperfusion injury.

  2007cited by this paper
• Sources of tissue factor.

  2006cited by this paper
• The placental bed in pregnancies complicated by primary antiphospholipid syndrome.

  2006cited by this paper
• A Novel C5a Receptor-Tissue Factor Cross-Talk in Neutrophils Links Innate Immunity to Coagulation Pathways1

  2006cited by this paper
• Blood coagulation-dependent inflammation. Coagulation-dependent inflammation and inflammation-dependent thrombosis.

  2006cited by this paper
• Tissue Factor

  2006cited by this paper
• Blood coagulation-dependent inflammation. Coagulation-dependent inflammation and inflammation-dependent thrombosis.

  2006cited by this paper
• In vivo regulation of neutrophil apoptosis by C5a during sepsis

  2006cited by this paper
• Tissue factor upregulation drives a thrombosis–inflammation circuit in relation to cardiovascular complications

  2006cited by this paper
• Differential gene expression in activated monocyte-derived macrophages following binding of factor VIIa to tissue factor

  2005cited by this paper
• A monoclonal antibody that inhibits mouse tissue factor function

  2005cited by this paper
• The interactions between inflammation and coagulation

  2005cited by this paper
• Fibrin independent proinflammatory effects of tissue factor in experimental crescentic glomerulonephritis.

  2004cited by this paper
• Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia.

  2004cited by this paper
• Role of tissue factor in haemostasis, thrombosis, angiogenesis and inflammation: lessons from low tissue factor mice

  2004cited by this paper
• Heparin prevents antiphospholipid antibody–induced fetal loss by inhibiting complement activation

  2004cited by this paper
• FVIIa:TF Induces Cell Survival via G12/G13-Dependent Jak/STAT Activation and BclXL Production

  2004cited by this paper
• Innate immunity in the antiphospholipid syndrome: role of toll-like receptors in endothelial cell activation by antiphospholipid antibodies.

  2004cited by this paper
• Tissue factor antisense oligonucleotides prevent renal ischemia-reperfusion injury

  2003cited by this paper
• Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome.

  2003cited by this paper
• Specificity of coagulation factor signaling

  2003cited by this paper
• The thrombomodulin–protein C system is essential for the maintenance of pregnancy

  2003cited by this paper
• Tissue factor as a proinflammatory agent

  2002cited by this paper
• Complement C3 Activation Is Required for Antiphospholipid Antibody-induced Fetal Loss

  2002cited by this paper
• From bloodjournal.hematologylibrary.org at PENN STATE UNIVERSITY on February 21, 2013. For personal use

  2002cited by this paper
• Effect of antisense oligonucleotides for tissue factor on hepatic ischemia-reperfusion injury in the rat.

  2001cited by this paper
• Endothelial cell activation by pore-forming structures: pivotal role for interleukin-1alpha.

  2000cited by this paper
• Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa.

  2000cited by this paper
• Tissue factor pathway and the antiphospholipid syndrome.

  2000cited by this paper
• Conditional gene targeting in macrophages and granulocytes using LysMcre mice

  1999cited by this paper
• Tissue factor in atherosclerosis.

  1999cited by this paper
• Aberrations of the Tissue Factor Pathway in Patients Positive for Lupus Anticoagulant

  1999cited by this paper
• Tissue factor and factor VIIa receptor/ligand interactions induce proinflammatory effects in macrophages.

  1999cited by this paper
• Monocyte tissue factor expression and ongoing complement generation in ventricular assist device patients.

  1998cited by this paper
• Regulation of the Tissue Factor Gene

  1997cited by this paper
• Impaired Inflammatory Responses in the Reverse Arthus Reaction Through Genetic Deletion of the C5a Receptor

  1997cited by this paper
• Monoclonal antibodies from NZW x BXSB F1 mice to beta2 glycoprotein I and cardiolipin. Species specificity and charge-dependent binding.

  1996cited by this paper
• Regulation of the tissue factor gene

  1995cited by this paper
• Synovial mononuclear phagocytes in rheumatoid arthritis and osteoarthritis: quantitative and functional aspects.

  1993cited by this paper
• Immunohistochemical study of tissue factor expression in normal intestine and idiopathic inflammatory bowel disease.

  1993cited by this paper
• Baboon model of Escherichia coli sepsis: description of its four stages and the role of tumor necrosis factor, tissue factors, and the protein C system in septic shock.

  1991cited by this paper
• Lethal E. coli septic shock is prevented by blocking tissue factor with monoclonal antibody.

  1991cited by this paper
• Monoclonal antibody analysis of purified and cell-associated tissue factor.

  1988cited by this paper

• Obstetric antiphospholipid syndrome: Advances in pathogenesis.

  2026cites this paper
• Complement involvement in antiphospholipid syndrome.

  2026cites this paper
• Deciphering the Role and Mechanism of Decidual Monocyte‐Derived Macrophage Infiltration in Obstetric Antiphospholipid Syndrome at Single‐Cell Resolution

  2025cites this paper
• The complement system in autoimmune diseases: pathogenesis, diagnostic markers, and therapeutic strategies

  2025cites this paper
• A role for TLR7 activation by miR-146a-3p in antiphospholipid antibody-induced trophoblast IL-8 and inflammasome-mediated IL-1β production.

  2025cites this paper
• Mechanism of antiphospholipid antibody-mediated thrombosis in antiphospholipid syndrome

  2025cites this paper
• Role of monocytes in the pathogenesis of antiphospholipid syndrome and potential therapeutic targets (Review)

  2025cites this paper
• Analytical Review: Neutrophil Extracellular Traps and Antiphospholipid syndrome.

  2025cites this paper
• Action of the Terminal Complement Pathway on Cell Membranes

  2025cites this paper
• Current Knowledge of Fetal Growth Restriction in Relation to Thrombosis at the Maternal‐Fetal Interface–Placenta and Umbilical Cord: A Literature Review

  2025cites this paper
• Antiphospholipid-exposed trophoblast-derived extracellular vesicles express elevated levels of TLR7/8-activating microRNAs and induce endometrial endothelial activation, in part, through TLR7.

  2024cites this paper
• An update on the endocrine manifestations of antiphospholipid syndrome

  2024cites this paper
• The role of neutrophils in autoimmune diseases.

  2024cites this paper
• The role of neutrophils and neutrophil extracellular traps (NETs) in stages, outcomes and pregnancy complications.

  2024cites this paper
• Association of Specific Antiphospholipid Antibodies to Platelet Count and Thrombocytopenia

  2024cites this paper
• Pregnancy in antiphospholipid syndrome: what should a rheumatologist know?

  2024cites this paper
• How We Interpret Thrombosis with Thrombocytopenia Syndrome?

  2024cites this paper
• ADP: the missing link between thrombosis and hemolysis

  2023cites this paper
• The pathogenesis of obstetric APS: a 2023 update.

  2023cites this paper
• Dysregulated low-density granulocyte contributes to early spontaneous abortion

  2023cites this paper
• The role of C5a receptors in autoimmunity.

  2023cites this paper
• Complement biomarkers in the antiphospholipid syndrome - Approaches to quantification and implications for clinical management.

  2023cites this paper
• The anaphylatoxin C5a: Structure, function, signaling, physiology, disease, and therapeutics.

  2023cites this paper
• Platelets and neutrophils co-drive procoagulant potential in secondary antiphospholipid syndrome during pregnancy.

  2022cites this paper
• Pathogenesis, Diagnosis and Management of Obstetric Antiphospholipid Syndrome: A Comprehensive Review

  2022cites this paper
• Mechanisms of immunothrombosis and vasculopathy in antiphospholipid syndrome

  2022cites this paper
• Investigation and Validation of Molecular Characteristics of Endometrium in Recurrent Miscarriage and Unexplained Infertility from a Transcriptomic Perspective

  2022cites this paper
• Alternative pathway activation in pregnancy, a measured amount “complements” a successful pregnancy, too much results in adverse events

  2022cites this paper
• The Expanding Role of Extracellular Traps in Inflammation and Autoimmunity: The New Players in Casting Dark Webs

  2022cites this paper
• Systemic-Immune-Inflammation Index as a Promising Biomarker for Predicting Perioperative Ischemic Stroke in Older Patients Who Underwent Non-cardiac Surgery

  2022cites this paper
• The Pathophysiology of The Antiphospholipid Syndrome: A Perspective From The Blood Coagulation System

  2022cites this paper
• An update on inflammation in antiphospholipid syndrome

  2022cites this paper
• The complement system and autoimmune diseases

  2022cites this paper
• Tissue factor in COVID-19-associated coagulopathy

  2022cites this paper
• A novel update on vitamin D in recurrent pregnancy loss

  2021cites this paper
• Pathophysiology of Antiphospholipid Syndrome

  2021cites this paper
• Thrombosis and Haemostasis Pathophysiology of the Antiphospholipid Antibody Syndrome

  2021cites this paper
• Complement C5a and Clinical Markers as Predictors of COVID-19 Disease Severity and Mortality in a Multi-Ethnic Population

  2021cites this paper
• Antiphospholipid Syndrome and Pregnancy-Diagnosis, Complications and Management: An Overview

  2021cites this paper
• Advocacy of targeting protease‐activated receptors in severe coronavirus disease 2019

  2021cites this paper
• Lipid presentation by the protein C receptor links coagulation with autoimmunity

  2021cites this paper
• It takes two to thrombosis: Hemolysis and complement.

  2021cites this paper
• Effects of anti‐beta 2‐glycoprotein 1 antibodies and its association with pregnancy‐related morbidity in antiphospholipid syndrome

  2021cites this paper
• Advancing research on recurrent pregnancy loss: Overcoming obstacles and opportunities for translation

  2021cites this paper
• Crosstalk between inflammation and coagulation: Focus on pregnancy related complications

  2021cites this paper
• Antiphospholipid-Syndrom bei Kindern und Jugendlichen

  2021cites this paper
• The Complement System

  2020cites this paper
• Complementopathies and precision medicine.

  2020cites this paper
• 16th International Congress on Antiphospholipid Antibodies Task Force Report on Antiphospholipid Syndrome Treatment Trends

  2020cites this paper
• Alternative complement pathway activation in thrombotic microangiopathy associated with lupus nephritis

  2020cites this paper
• Antiphospholipid syndrome: Complement activation, complement gene mutations, and therapeutic implications

  2020cites this paper
• NETs in APS: Current Knowledge and Future Perspectives

  2020cites this paper
• 16th International Congress on Antiphospholipid Antibodies Task Force Report on Catastrophic Antiphospholipid Syndrome

  2020cites this paper
• Antiphospholipid antibody‐activated NETs exacerbate trophoblast and endothelial cell injury in obstetric antiphospholipid syndrome

  2020cites this paper
• Neutrophils in the Pathogenesis of Rheumatic Diseases: Fueling the Fire

  2020cites this paper
• Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis

  2020cites this paper
• Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS.

  2019cites this paper
• Is there a role for immunosuppression in antiphospholipid syndrome?

  2019cites this paper
• Immunomodulatory Effects of Vitamin D in Pregnancy and Beyond

  2019cites this paper
• Acute ST-elevation myocardial infarction in a young patient with antiphospholipid syndrome

  2019cites this paper
• Acute Kidney Injury During Pregnancy

  2019cites this paper
• Complement in the Pathophysiology of the Antiphospholipid Syndrome

  2019cites this paper
• Management of Antiphospholipid Syndrome in Patients with Systemic Lupus Erythematosus

  2019cites this paper
• Post-translational modifications of proteins in antiphospholipid antibody syndrome

  2019cites this paper
• Tissue factor pathway inhibitor primes monocytes for antiphospholipid antibody-induced thrombosis.

  2019cites this paper
• Differential contribution of C5aR and C5b-9 pathways to renal thrombic microangiopathy and macrovascular thrombosis in mice carrying an atypical hemolytic syndrome-related factor H mutation.

  2019cites this paper
• The Complement System

  2019cites this paper
• Mechanisms of Antiphospholipid Syndrome Induction: Role of NKT Cells

  2019cites this paper
• Genome-wide DNA methylation analysis in primary antiphospholipid syndrome neutrophils.

  2018cites this paper
• Pathogenesis of antiphospholipid syndrome: recent insights and emerging concepts

  2018influential citation
• Pathogenic Role of Complement in Antiphospholipid Syndrome and Therapeutic Implications

  2018cites this paper
• Investigating The Effect And Mechanism Of Antiphospholipid Antibodies On Human Endometrial Endothelial Cell Function And The Impact Of Current Standard Therapies

  2018cites this paper
• The role of neutrophils in thrombosis.

  2018cites this paper
• Fetal Growth Restriction Induced by Transient Uterine Ischemia–Reperfusion: Differential Responses in Different Mouse Strains

  2018cites this paper
• Are Anti-β2 Glycoprotein 1 Antibodies Associated with Placenta-Mediated Pregnancy Complications? A Nested Case–Control Study

  2018cites this paper
• Therapeutic Roles of Statins in Gynecology and Obstetrics: The Current Evidence

  2018cites this paper
• Pravastatin for Preeclampsia Prevention and Treatment

  2018cites this paper
• Neutrophils and redox stress in the pathogenesis of autoimmune disease.

  2018cites this paper
• Vitamin D and Anti-Phospholipid Antibody Syndrome: A Comprehensive Review

  2018cites this paper
• Complement C5 but not C3 is expendable for tissue factor activation by cofactor-independent antiphospholipid antibodies.

  2018cites this paper
• Neutrophil Extracellular Traps, Antiphospholipid Antibodies and Treatment

  2017influential citation
• Lung fibrosis-associated soluble mediators and bronchoalveolar lavage from idiopathic pulmonary fibrosis patients promote the expression of fibrogenic factors in subepithelial lung myofibroblasts.

  2017cites this paper
• Factor Xa Mediates Calcium Flux in Endothelial Cells and is Potentiated by Igg From Patients With Lupus and/or Antiphospholipid Syndrome

  2017influential citation
• Clinical Risk Assessment in the Antiphospholipid Syndrome: Current Landscape and Emerging Biomarkers

  2017cites this paper
• Complement activation, a threat to pregnancy

  2017cites this paper
• 15th International Congress on Antiphospholipid Antibodies Task Force on Antiphospholipid Syndrome Treatment Trends Report

  2017cites this paper
• Mechanisms of Antiphospholipid Antibody-Mediated Pregnancy Morbidity

  2017cites this paper
• Haemolytic uraemic syndrome.

  2017cites this paper
• Prevention and Treatment of Obstetric Antiphospholipid Syndrome

  2017cites this paper
• Diagnosis and management of the antiphospholipid syndrome.

  2017cites this paper
• Efficacy of Different Treatment Regimens for Antiphospholipid Syndrome-related Recurrent Spontaneous Abortion

  2017cites this paper
• Pravastatin to treat and prevent preeclampsia. Preclinical and clinical studies.

  2017cites this paper
• Neutrophil extracellular traps are critical for pregnancy loss in sphingosine kinase–deficient mice on 129Sv/C57BL/6 background

  2017cites this paper
• Major Histocompatibility Complex Class II Alleles Influence Induction of Pathogenic Antiphospholipid Antibodies in a Mouse Model of Thrombosis

  2017cites this paper
• Clinical and Prognostic Significance of Non-criteria Antiphospholipid Antibody Tests

  2017cites this paper
• CD39 and CD73 activity are protective in a mouse model of antiphospholipid antibody-induced miscarriages.

  2017cites this paper
• Delineating the deranged immune system in the antiphospholipid syndrome.

  2016cites this paper
• Neutrophil Involvement in Autoimmune Rheumatic Disease: The Modulatory Roles of Hypoxia and Autoimmune Immunoglobulin G

  2016cites this paper
• Mouse is the new woman? Translational research in reproductive immunology

  2016influential citation
• Hypercoagulation and complement: Connected players in tumor development and metastases.

  2016cites this paper