Seasonal Variation of Biosynthetic Path Selectivity of Flavonoids, and Content and Antioxidant Activity of Metabolites in Tetrastigma Hemsleyanum Diels Et Gilg

This work investigated the seasonal variations in biosynthetic path selectivity of nine individual flavonoids, and content and antioxidant activity of three major metabolites in Tetrastigma hemsleyanum. The results revealed that under conditions of precipitation (2.0~6.6 mm), temperature (17.5~24.1°C), humidity (67.3~80.2%) and sunshine duration (3.4~5.8 h) in April and May, the total content of flavonoids reached higher levels between 282 and 394.5 μg/g; in the second half of April with the highest accumulation of flavonoids, the production selectivity (PS) of isoorientin, orientin, rutin, isoquercitin, kaempferol-3-0-rutinoside, astragalin, quercetin, apigenin and kaempferol were 0.30, 0.06, 0.07, 0.07, 0.00, 0.04, 0.38, 0.05 and 0.03, respectively; also according to the reaction network consisting of three main pathways for flavonoids syntheses in T. hemsleyanum, the selectivity of reaction Path II to synthesize quercetin, isoquercitin and rutin in April, May and June fluctuated between 0.52 and 0.66, much higher than that of reaction Path I or Path III.

• Publication year

  2021

• Venue

  Unknown venue

• Publication date

  2021-01-25

• Fields of study

  Chemistry, Environmental Science

• Identifiers
  DOI 10.21203/RS.3.RS-151189/V1
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• A Novel Method

  2020cited by this paper
• Radix Tetrastigma flavonoids inhibit the migration and promote the apoptosis of A549 cells both in vitro and in vivo

  2020cited by this paper
• Polysaccharides from Tetrastigma hemsleyanum Diels et Gilg: Extraction optimization, structural characterizations, antioxidant and antihyperlipidemic activities in hyperlipidemic mice.

  2019cited by this paper
• Structural characterization, hypoglycemic effects and mechanism of a novel polysaccharide from Tetrastigma hemsleyanum Diels et Gilg.

  2019cited by this paper
• Plant Secondary Metabolites Modulate Insect Behavior-Steps Toward Addiction?

  2018cited by this paper
• Seasonal variation of natural products in European trees

  2018cited by this paper
• Seasonal effects on antioxidant and anti-HIV activities of Brazilian seaweeds

  2018cited by this paper
• Legume-Rhizobium Symbiosis: Secondary Metabolites, Free Radical Processes, and Effects of Heavy Metals

  2018cited by this paper
• Grape pomace as a source of phenolic compounds and diverse bioactive properties.

  2018influential reference
• Seasonal variation of secondary metabolites in nine different bryophytes

  2018cited by this paper
• Ethylacetate extract from Tetrastigma hemsleyanum inhibits proliferation and induces apoptosis in HepG2 and SMMC-7721 cells

  2018influential reference
• Low synthesis of secondary compounds in the lichen Lobaria pulmonaria infected by the lichenicolous fungus Plectocarpon lichenum.

  2018cited by this paper
• Response of Plant Secondary Metabolites to Environmental Factors

  2018cited by this paper
• The effects of season and water availability on chemical composition, secondary metabolites and biological activity in plants

  2018cited by this paper
• Effect of endophytic fungi on the host plant growth, expression of expansin gene and flavonoid content in Tetrastigma hemsleyanum Diels & Gilg ex Diels

  2017cited by this paper
• Estimating the carbohydrate content of various forms of tobacco by phenol-sulfuric acid method

  2017influential reference
• The phytochemical composition, metabolites, bioavailability and in vivo antioxidant activity of Tetrastigma hemsleyanum leaves in rats

  2017cited by this paper
• The phytochemical

  2017cited by this paper
• Seasonal Dynamics of Metabolites in Needles of Taxus wallichiana var. mairei

  2016cited by this paper
• Influence of Ecological Factors on the Production of Active Substances in the Anti-Cancer Plant Sinopodophyllum hexandrum (Royle) T.S. Ying

  2015cited by this paper
• Flavonoid transport mechanisms: how to go, and with whom.

  2015cited by this paper
• Molecular phylogeography and ecological niche modelling of a widespread herbaceous climber, Tetrastigma hemsleyanum (Vitaceae): insights into Plio-Pleistocene range dynamics of evergreen forest in subtropical China.

  2015cited by this paper
• Rapid characterization of chemical constituents in Radix Tetrastigma, a functional herbal mixture, before and after metabolism and their antioxidant/antiproliferative activities

  2015cited by this paper
• Steroids from the aerial parts of Leonurus japonicus

  2015influential reference
• Phytotoxicity of 4,8-Dihydroxy-1-tetralone Isolated from Carya cathayensis Sarg. to Various Plant Species

  2014cited by this paper
• Qualitative and quantitative analysis of phenolics in Tetrastigma hemsleyanum and their antioxidant and antiproliferative activities.

  2013cited by this paper
• Compositional differences of phenolic compounds between black currant (Ribes nigrum L.) cultivars and their response to latitude and weather conditions.

  2012cited by this paper
• Transcriptional regulation of plant secondary metabolism.

  2012cited by this paper
• Secondary Lichen Compounds as Protection Against Excess Solar Radiation and Herbivores

  2012cited by this paper
• BVOCs and global change.

  2010cited by this paper
• Effect of photoperiod on flavonoid pathway activity in sweet potato (Ipomoea batatas (L.) Lam.) leaves

  2010cited by this paper
• CYP93G2 Is a Flavanone 2-Hydroxylase Required for C-Glycosylflavone Biosynthesis in Rice1[W]

  2010cited by this paper
• Environmental regulation of leaf colour in red 35S:PAP1 Arabidopsis thaliana.

  2009cited by this paper
• Plant behavioural ecology: dynamic plasticity in secondary metabolites.

  2009cited by this paper
• Immunoregulatory effects of ethyl-acetate fraction of extracts from Tetrastigma hemsleyanum Diels et. Gilg on immune functions of ICR mice.

  2008cited by this paper
• UV screening in higher plants induced by low temperature in the absence of UV-B radiation

  2007cited by this paper
• Biosynthesis of flavonoids and effects of stress.

  2002cited by this paper
• Analysis of complex mixtures of flavonoids and polyphenols by high-performance liquid chromatography electrochemical detection methods.

  2001cited by this paper
• Jasmonate-inducible plant defences cause increased parasitism of herbivores

  1999cited by this paper
• Qualitative and Quantitative Analysis.

  1931cited by this paper

• No citing papers are available for this paper.