Transition metal- and light-free radical borylation of alkyl bromides and iodides using silane.

We report operationally simple and neutral conditions for borylation of alkyl bromides and iodides to alkyl boronic esters under transition metal- and light-free conditions. A series of substrates with a wide range of functional groups were effectively transformed into the borylation products in moderate to good yields. Mechanistic studies, including radical clock experiments and DFT calculations, gave detailed insight into the radical borylation process.

• Publication year

  2021

• Venue

  Chemical Communications

• Publication date

  2021-05-12

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1039/d1cc02134fPMID 33978007
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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