Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth muscle cells: modulation by glucocorticoids and beta-agonists.

No abstract is available for this paper.

• Publication year

  2002

• Venue

  American Journal of Respiratory Cell and Molecular Biology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  PMID 11919083
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Regulation of TNF-alpha-induced eotaxin release from cultured human airway smooth muscle cells by beta2-agonists and corticosteroids.

  2001cited by this paper
• Th1 Cytokines Stimulate RANTES Chemokine Secretion by Human Astroglial Cells Depending on De Novo Transcription

  2001cited by this paper
• beta(2)-adrenoceptor agonists inhibit release of eosinophil-activating cytokines from human airway smooth muscle cells.

  2001cited by this paper
• Activation of class IA PI3K stimulates DNA synthesis in human airway smooth muscle cells.

  2001cited by this paper
• Synergistic inhibition by beta(2)-agonists and corticosteroids on tumor necrosis factor-alpha-induced interleukin-8 release from cultured human airway smooth-muscle cells.

  2000cited by this paper
• Interactions between corticosteroids and beta-adrenergic agonists in asthma disease induction, progression, and exacerbation.

  2000cited by this paper
• Endogenous and Exogenous IL-6 Inhibit Aeroallergen-Induced Th2 Inflammation1

  2000cited by this paper
• Tumor necrosis factor-alpha enhances mRNA expression and secretion of interleukin-6 in cultured human airway smooth muscle cells.

  2000cited by this paper
• Tumor necrosis factor-alpha-induced secretion of RANTES and interleukin-6 from human airway smooth-muscle cells. Modulation by cyclic adenosine monophosphate.

  2000cited by this paper
• Adenosine - cyclic AMP pathways and cytokine expression.

  1999cited by this paper
• Up-regulation of ICAM-1 by cytokines in human tracheal smooth muscle cells involves an NF-kappa B-dependent signaling pathway that is only partially sensitive to dexamethasone.

  1999cited by this paper
• Stimulus‐specific regulation of chemokine expression involves differential activation of the redox‐responsive transcription factors AP‐1 and NF‐κB

  1999cited by this paper
• Transforming growth factor-beta1 induces interleukin-6 expression via activating protein-1 consisting of JunD homodimers in primary human lung fibroblasts.

  1999cited by this paper
• The Nuclear Factor-κB Engages CBP/p300 and Histone Acetyltransferase Activity for Transcriptional Activation of the Interleukin-6 Gene Promoter*

  1999cited by this paper
• Chemokines and asthma: redundancy of function or a coordinated effort?

  1999cited by this paper
• Critical Role of cAMP Response Element Binding Protein Expression in Hypoxia-elicited Induction of Epithelial Tumor Necrosis Factor-α*

  1999cited by this paper
• Airway remodeling in asthma.

  1999cited by this paper
• CD40-mediated signal transduction in human airway smooth muscle.

  1998cited by this paper
• The beta-adrenoceptor.

  1998cited by this paper
• Efficacy and safety of inhaled corticosteroids. New developments.

  1998cited by this paper
• Nuclear factor-kappa B potently up-regulates the promoter activity of RANTES, a chemokine that blocks HIV infection.

  1997cited by this paper
• Synergy between Interferon-γ and Tumor Necrosis Factor-α in Transcriptional Activation Is Mediated by Cooperation between Signal Transducer and Activator of Transcription 1 and Nuclear Factor κB*

  1997cited by this paper
• Genomic organization, sequence, and transcriptional regulation of the human eotaxin gene.

  1997cited by this paper
• Eosinophil recruitment following allergen challenge is associated with the release of the chemokine RANTES into asthmatic airways.

  1996cited by this paper
• Increased MCP-1, RANTES, and MIP-1alpha in bronchoalveolar lavage fluid of allergic asthmatic patients.

  1996cited by this paper
• Cyclic AMP Inhibition of Thrombin-induced Growth in Vascular Smooth Muscle Cells Correlates with Decreased JNK1 Activity and c-Jun Expression*

  1996cited by this paper
• Mitogen-activated Protein Kinase Pathway and AP-1 Are Activated during cAMP-induced Melanogenesis in B-16 Melanoma Cells (*)

  1995cited by this paper
• IL-1 beta and IL-6 induce hyperplasia and hypertrophy of cultured guinea pig airway smooth muscle cells.

  1995cited by this paper
• Effects of dexamethasone on cytokine and phorbol ester stimulated c-Fos and c-Jun DNA binding and gene expression in human lung.

  1994cited by this paper
• Multiple regulatory elements in the interleukin-6 gene mediate induction by prostaglandins, cyclic AMP, and lipopolysaccharide

  1994cited by this paper
• Physical association and functional antagonism between the p65 subunit of transcription factor NF-kappa B and the glucocorticoid receptor.

  1994cited by this paper
• Genomic organization and transcriptional regulation of the RANTES chemokine gene.

  1993cited by this paper
• Control of transcription activation by steroid hormone receptors

  1992cited by this paper
• Cytokines in symptomatic asthma airways.

  1992cited by this paper
• Antitumor promotion and antiinflammation: down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone.

  1990cited by this paper
• A human airway smooth muscle cell line that retains physiological responsiveness.

  1989cited by this paper
• Activation of the human "beta 2-interferon/hepatocyte-stimulating factor/interleukin 6" promoter by cytokines, viruses, and second messenger agonists.

  1988cited by this paper

• Increased circulating levels of SP-D and IL-10 are associated with the development of disease severity and pulmonary fibrosis in patients with COVID-19

  2025cites this paper
• Genomic crosstalk between carbachol, a muscarinic receptor agonist, and the long-acting β2-adrenoceptor agonist, indacaterol, in human airway epithelial cells.

  2025cites this paper
• Induction of chronic asthma up regulated the transcription of senile factors in male rats

  2024cites this paper
• T cell and airway smooth muscle interaction: a key driver of asthmatic airway inflammation and remodelling.

  2024cites this paper
• Th1 cytokines synergize to change gene expression and promote corticosteroid insensitivity in pediatric airway smooth muscle

  2022cites this paper
• Glucocorticoid Insensitivity in Asthma: The Unique Role for Airway Smooth Muscle Cells

  2022influential citation
• Functional and Molecular Immune Response of Rainbow Trout (Oncorhynchus mykiss) Following Challenge with Yersinia ruckeri

  2022cites this paper
• Phenethyl Isothiocyanate Suppresses the Proinflammatory Cytokines in Human Glioblastoma Cells through the PI3K/Akt/NF-κB Signaling Pathway In Vitro

  2022cites this paper
• Paucigranulocytic Asthma: Potential Pathogenetic Mechanisms, Clinical Features and Therapeutic Management

  2022cites this paper
• Assessment of the RANTES Level Correlation and Selected Inflammatory and Pro-Angiogenic Molecules Evaluation of Their Influence on CRC Clinical Features: A Preliminary Observational Study

  2022cites this paper
• Cardiometabolic risks and atherosclerotic disease in ApoE knockout mice: Effect of spinal cord injury and Salsalate anti-inflammatory pharmacotherapy

  2021cites this paper
• CCR5 and Biological Complexity: The Need for Data Integration and Educational Materials to Address Genetic/Biological Reductionism at the Interface of Ethical, Legal, and Social Implications

  2021cites this paper
• A new p65 isoform that bind the glucocorticoid hormone and is expressed in inflammation liver diseases and COVID-19

  2021cites this paper
• Intestinal microbial communities and Holdemanella isolated from HIV+/− men who have sex with men increase frequencies of lamina propria CCR5+ CD4+ T cells

  2021cites this paper
• STIM1 is a core trigger of airway smooth muscle remodeling and hyperresponsiveness in asthma

  2021cites this paper
• An inherent dysfunction in soluble guanylyl cyclase is present in the airway of severe asthmatics and is associated with aberrant redox enzyme expression and compromised NO-cGMP signaling

  2020cites this paper
• Transcriptome-Level Interactions between Budesonide and Formoterol Provide Insight into the Mechanism of Action of Inhaled Corticosteroid/Long-Acting β2-Adrenoceptor Agonist Combination Therapy in Asthma

  2020influential citation
• Important lessons learned from studies on the pharmacology of glucocorticoids in human airway smooth muscle cells: Too much of a good thing may be a problem.

  2020cites this paper
• Glucocorticoids regulate pentraxin-3 expression in human airway smooth muscle cells

  2019cites this paper
• Dietary Fatty Acids Amplify Inflammatory Responses to Infection through p38 MAPK Signaling

  2019cites this paper
• Specificity of NHERF1 regulation of GPCR signaling and function in human airway smooth muscle

  2019cites this paper
• Airway Hyperresponsiveness and Bronchoalveolar Fluid Inflammatory Cells in Obese Asthmatic Male Rats

  2019cites this paper
• ADHD pathogenesis in the immune, endocrine and nervous systems of juvenile and maturating SHR and WKY rats

  2019cites this paper
• Cytotoxicity analysis of ambient fine particle in BEAS-2B cells on an air-liquid interface (ALI) microfluidics system.

  2019cites this paper
• Flavonoids reduces lipopolysaccharide-induced release of inflammatory mediators in human bronchial epithelial cells: Structure-activity relationship.

  2019cites this paper
• Comparison of inflammatory urine markers in patients with interstitial cystitis and overactive bladder

  2018cites this paper
• Entzündungssignal RANTES / CCL5 aus dem Kieferknochen

  2018cites this paper
• Th1 cytokines TNF- (cid:2) and IFN- (cid:3) promote corticosteroid resistance in developing human airway smooth muscle

  2018cites this paper
• Selectively targeting prostanoid E (EP) receptor-mediated cell signalling pathways: Implications for lung health and disease.

  2018cites this paper
• Follicular B Cells Promote Atherosclerosis via T Cell–Mediated Differentiation Into Plasma Cells and Secreting Pathogenic Immunoglobulin G

  2018cites this paper
• Titanium implants and silent inflammation in jawbone—a critical interplay of dissolved titanium particles and cytokines TNF-α and RANTES/CCL5 on overall health?

  2018cites this paper
• Long-Acting β2-Adrenoceptor Agonists Enhance Glucocorticoid Receptor (GR)–Mediated Transcription by Gene-Specific Mechanisms Rather Than Generic Effects via GR

  2018cites this paper
• Interleukin‐6 gets involved in response to bacterial infection and promotes antibody production in Nile tilapia (Oreochromis niloticus)

  2018cites this paper
• A bronchoprotective role for Rgs2 in a murine model of lipopolysaccharide-induced airways inflammation

  2018cites this paper
• Phenotype and Functional Features of Human Telomerase Reverse Transcriptase Immortalized Human Airway Smooth Muscle Cells from Asthmatic and Non-Asthmatic Donors

  2018cites this paper
• Protective Roles for RGS2 in a Mouse Model of House Dust Mite-Induced Airway Inflammation

  2017cites this paper
• University of Groningen Inhibition of phosphodiesterase 4 modulates cytokine induction from toll like receptor activated , but not rhinovirus infected , primary human airway smooth muscle

  2017cites this paper
• CD38 in the pathogenesis of allergic airway disease: Potential therapeutic targets.

  2017cites this paper
• β2-Adrenoceptor Function in Asthma.

  2017cites this paper
• Anti-inflammatory and vasoconstrictive properties of Potentilla erecta - A traditional medicinal plant from the northern hemisphere.

  2017cites this paper
• B cells influence sex specificity of arthritis via myeloid suppressors and chemokines in humanized mice.

  2017cites this paper
• MicroRNA Mediated Chemokine Responses in Human Airway Smooth Muscle Cells

  2016cites this paper
• Bronchoprotection and bronchorelaxation in asthma: New targets, and new ways to target the old ones.

  2016cites this paper
• Inundation of asthma target research: Untangling asthma riddles.

  2016cites this paper
• Glucocorticoid and TNF signaling converge at A20 (TNFAIP3) to repress airway smooth muscle cytokine expression.

  2016cites this paper
• Neutrophilic and Pauci-immune Phenotypes in Severe Asthma.

  2016cites this paper
• Understanding how long‐acting β2‐adrenoceptor agonists enhance the clinical efficacy of inhaled corticosteroids in asthma – an update

  2016cites this paper
• Corticosteroid‐Induced MKP‐1 Represses Pro‐Inflammatory Cytokine Secretion by Enhancing Activity of Tristetraprolin (TTP) in ASM Cells

  2016cites this paper
• Characterization, promoter analysis and expression of the interleukin-6 gene in blunt snout bream, Megalobrama amblycephala

  2016cites this paper
• Role of N-methyl-D-aspartate receptors in the regulation of human airway smooth muscle function and airway responsiveness

  2015cites this paper
• Glucocorticoid Signaling

  2015cites this paper
• Fetal human airway smooth muscle cell production of leukocyte chemoattractants is differentially regulated by fluticasone

  2015cites this paper
• Biomarkers in Lung Diseases : from Pathogenesis to Prediction to New Therapies Resolvin E 1 normalizes contractility , Ca 2 sensitivity and smooth muscle cell migration rate in TNF-- and IL-6-pretreated human pulmonary arteries

  2015cites this paper
• CALL FOR PAPERS Biomarkers in Lung Diseases: from Pathogenesis to Prediction to New Therapies Resolvin E 1 normalizes contractility, Ca 2 (cid:2) sensitivity and smooth muscle cell migration rate in TNF- (cid:3) - and IL-6-pretreated human pulmonary arteries

  2015cites this paper
• Glucocorticoids and the Lung.

  2015cites this paper
• Effect of the plant derivative Compound A on the production of corticosteroid-resistant chemokines in airway smooth muscle cells.

  2015cites this paper
• Age-Associated Increase in Cytokine Production During Systemic Inflammation-II: The Role of IL-1β in Age-Dependent IL-6 Upregulation in Adipose Tissue.

  2015cites this paper
• Quercetin alleviates 4-hydroxynonenal-induced cytotoxicity and inflammation in ARPE-19 cells.

  2015cites this paper
• MicroRNA Regulation of Airway Inflammation and Airway Smooth Muscle Function: Relevance to Asthma

  2015cites this paper
• The Plant Derivative Compound A Inhibits the Production of Corticosteroid-resistant Chemokines by Airway Smooth Muscle Cells.

  2015cites this paper
• Resolvin E1 normalizes contractility, Ca2+ sensitivity and smooth muscle cell migration rate in TNF-α- and IL-6-pretreated human pulmonary arteries.

  2015cites this paper
• Inhibition of dengue virus production and cytokine/chemokine expression by ribavirin and compound A.

  2015cites this paper
• Monocyte‐derived fibrocytes induce an inflammatory phenotype in airway smooth muscle cells

  2014cites this paper
• Exploring the role of microRNAs in airway smooth muscle biology and asthma therapy

  2014cites this paper
• Angiotensin II type 1 receptor blockade suppresses light-induced neural damage in the mouse retina.

  2014cites this paper
• Sphingosine 1-Phosphate Induces Neutrophil Chemoattractant IL-8: Repression by Steroids

  2014cites this paper
• Andrographolide inhibits TNFα-induced ICAM-1 expression via suppression of NADPH oxidase activation and induction of HO-1 and GCLM expression through the PI3K/Akt/Nrf2 and PI3K/Akt/AP-1 pathways in human endothelial cells.

  2014cites this paper
• Non-raft adenylyl cyclase 2 defines a cAMP signaling compartment that selectively regulates IL-6 expression in airway smooth muscle cells: differential regulation of gene expression by AC isoforms

  2014cites this paper
• Crosstalk between beta-2-adrenoceptor and muscarinic acetylcholine receptors in the airway.

  2014cites this paper
• b 2-Adrenergic receptors in immunity and inflammation : Stressing NF-j B

  2014influential citation
• Rhinovirus-Infected Epithelial Cells Produce More IL-8 and RANTES Compared With Other Respiratory Viruses

  2013cites this paper
• Long-Acting β2-Agonists Increase Fluticasone Propionate-Induced Mitogen-Activated Protein Kinase Phosphatase 1 (MKP-1) in Airway Smooth Muscle Cells

  2013cites this paper
• Identification of Chemokines Associated with the Recruitment of Decidual Leukocytes in Human Labour: Potential Novel Targets for Preterm Labour

  2013cites this paper
• Corticosteroids inhibit sphingosine 1-phosphate-induced interleukin-6 secretion from human airway smooth muscle via mitogen-activated protein kinase phosphatase 1-mediated repression of mitogen and stress-activated protein kinase 1.

  2013cites this paper
• Non‐raft AC2 defines a cAMP signaling compartment that selectively regulates IL‐6 expression in airway smooth muscle cells

  2013cites this paper
• Inhibition of phosphodiesterase 4 modulates cytokine induction from toll like receptor activated, but not rhinovirus infected, primary human airway smooth muscle

  2013cites this paper
• Exchange Protein Directly Activated by cAMP (epac): A Multidomain cAMP Mediator in the Regulation of Diverse Biological Functions

  2013cites this paper
• Glucocorticoids and airway smooth muscle: some answers, more questions.

  2013cites this paper
• Distinct PKA and Epac compartmentalization in airway function and plasticity.

  2013cites this paper
• Sphingosine Kinase 1 Regulates Tumor Necrosis Factor-mediated RANTES Induction through p38 Mitogen-activated Protein Kinase but Independently of Nuclear Factor κB Activation*

  2013cites this paper
• CCL5 as a potential immunotherapeutic target in triple-negative breast cancer

  2013cites this paper
• Anti-Inflammatory Dimethylfumarate: A Potential New Therapy for Asthma?

  2013cites this paper
• Cloning and characterisation of rainbow trout Interleukin (IL)-17A/F2 and IL-17RA:

  2012cites this paper
• β2-Agonists upregulate PDE4 mRNA but not protein or activity in human airway smooth muscle cells from asthmatic and nonasthmatic volunteers.

  2012cites this paper
• Prostaglandins but not leukotrienes alter extracellular matrix protein deposition and cytokine release in primary human airway smooth muscle cells and fibroblasts.

  2012cites this paper
• Role of cold shock Y-box protein-1 in inflammation, atherosclerosis and organ transplant rejection.

  2012cites this paper
• Thiazolidinediones inhibit airway smooth muscle release of the chemokine CXCL10: in vitro comparison with current asthma therapies

  2012influential citation
• TLR2 ligand engagement upregulates airway smooth muscle TNFα-induced cytokine production.

  2012cites this paper
• Cloning and Characterization of Rainbow Trout Interleukin-17A/F2 (IL-17A/F2) and IL-17 Receptor A: Expression during Infection and Bioactivity of Recombinant IL-17A/F2

  2012cites this paper
• Motility, survival, and proliferation.

  2012cites this paper
• Airway smooth muscle in asthma: just a target for bronchodilation?

  2012cites this paper
• Thiazolidinediones inhibit airway smooth muscle release of the chemokine CXCL 10

  2012influential citation
• Intracellular Interaction of Interleukin (IL)-32α with Protein Kinase Cϵ (PKCϵ) and STAT3 Protein Augments IL-6 Production in THP-1 Promonocytic Cells*

  2012cites this paper
• Expression profiling identifies Klf15 as a glucocorticoid target that regulates airway hyperresponsiveness.

  2011cites this paper
• Effects of β 2 Agonists, Corticosteroids, and Novel Therapies on Rhinovirus-Induced Cytokine Release and Rhinovirus Replication in Primary Airway Fibroblasts

  2011cites this paper
• Transcriptional regulation of inflammatory genes associated with severe asthma.

  2011cites this paper
• Beta-2-receptor regulation of immunomodulatory proteins in airway smooth muscle.

  2011cites this paper
• Andrographolide inhibits ICAM-1 expression and NF-κB activation in TNF-α-treated EA.hy926 cells.

  2011cites this paper
• Hypoxic damage to pancreatic beta cells--the hidden link between sleep apnea and diabetes.

  2011cites this paper
• Harnessing the clinical efficacy of phosphodiesterase 4 inhibitors in inflammatory lung diseases: dual-selective phosphodiesterase inhibitors and novel combination therapies.

  2011cites this paper