Accurate prediction of scorpion toxin functional properties from primary structures.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Journal of Molecular Graphics and Modelling

• Publication date

  2005-09-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/J.JMGM.2005.01.003PMID 15950506
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Chlorotoxin‐sensitive Ca2+‐activated Cl− channel in type R2 reactive astrocytes from adult rat brain

  2003cited by this paper
• Bioinformatics for Venom and Toxin Sciences

  2003cited by this paper
• Novel interactions between K+ channels and scorpion toxins.

  2003cited by this paper
• kappa-Hefutoxin1, a novel toxin from the scorpion Heterometrus fulvipes with unique structure and function. Importance of the functional diad in potassium channel selectivity.

  2002cited by this paper
• SCORPION, a molecular database of scorpion toxins.

  2002cited by this paper
• Tamapin, a Venom Peptide from the Indian Red Scorpion (Mesobuthus tamulus) That Targets Small Conductance Ca2+-activated K+ Channels and Afterhyperpolarization Currents in Central Neurons*

  2002cited by this paper
• A depressant insect toxin with a novel analgesic effect from scorpion Buthus martensii Karsch.

  2001cited by this paper
• Purification, amino-acid sequence and partial characterization of two toxins with anti-insect activity from the venom of the South American scorpion Tityus bahiensis (Buthidae).

  2001cited by this paper
• Tamulustoxin: a novel potassium channel blocker from the venom of the Indian red scorpion Mesobuthus tamulus.

  2001cited by this paper
• Precursor nucleotide sequence and genomic organization of BmTXKS1, a new scorpion toxin-like peptide from Buthus martensii Karsch.

  2001cited by this paper
• Purification, characterization, and primary structure of four depressant insect-selective neurotoxin analogs from scorpion (Buthus sindicus) venom.

  2001cited by this paper
• OsK2, a new selective inhibitor of Kv1.2 potassium channels purified from the venom of the scorpion Orthochirus scrobiculosus.

  2001cited by this paper
• Functional site of bukatoxin, an α‐type sodium channel neurotoxin from the Chinese scorpion (Buthus martensi Karsch) venom: probable role of the 52PDKVP56 loop

  2001cited by this paper
• An ERG Channel Inhibitor from the Scorpion Buthus eupeus*

  2001cited by this paper
• A new class of scorpion toxin binding sites related to an A‐type K+ channel: pharmacological characterization and localization in rat brain

  2001cited by this paper
• Structural basis for alpha-K toxin specificity for K+ channels revealed through the solution 1H NMR structures of two noxiustoxin-iberiotoxin chimeras.

  2001cited by this paper
• Evidence for a position‐specific deletion as an evolutionary link between long‐ and short‐chain scorpion toxins

  2001cited by this paper
• Molecular cloning and characterization of four scorpion K(+)-toxin-like peptides: a new subfamily of venom peptides (alpha-KTx14) and genomic analysis of a member.

  2001cited by this paper
• Chlorotoxin does not inhibit volume‐regulated, calcium‐activated and cyclic AMP‐activated chloride channels

  2000cited by this paper
• Scorpion neurotoxins: structure/function relationships and application in agriculture†

  2000cited by this paper
• BmK AS: new scorpion neurotoxin binds to distinct receptor sites of mammal and insect voltage-gated sodium channels.

  2000cited by this paper
• BmK AS: New scorpion neurotoxin binds to distinct receptor sites of mammal and insect voltage‐gated sodium channels

  2000cited by this paper
• Peptides and genes coding for scorpion toxins that affect ion-channels.

  2000influential reference
• Antihyperalgesia effect of BmK IT2, a depressant insect-selective scorpion toxin in rat by peripheral administration.

  2000cited by this paper
• Sequence and electrophysiological characterization of two insect‐selective excitatory toxins from the venom of the Chinese scorpion Buthus martensi

  2000cited by this paper
• A toxin to nervous, cardiac, and endocrine ERG K+ channels isolated from Centruroides noxius scorpion venom

  1999cited by this paper
• A Scorpion α-Like Toxin That Is Active on Insects and Mammals Reveals an Unexpected Specificity and Distribution of Sodium Channel Subtypes in Rat Brain Neurons

  1999cited by this paper
• Dynamic Diversification from a Putative Common Ancestor of Scorpion Toxins Affecting Sodium, Potassium, and Chloride Channels

  1999cited by this paper
• Scorpion α‐like toxins, toxic to both mammals and insects, differentially interact with receptor site 3 on voltage‐gated sodium channels in mammals and insects

  1999cited by this paper
• A unified nomenclature for short-chain peptides isolated from scorpion venoms: alpha-KTx molecular subfamilies.

  1999cited by this paper
• Scorpion toxins specific for Na+-channels.

  1999cited by this paper
• Functional Anatomy of Scorpion Toxins Affecting Sodium Channels

  1998cited by this paper
• An excitatory scorpion toxin with a distinctive feature: an additional alpha helix at the C terminus and its implications for interaction with insect sodium channels.

  1998cited by this paper
• Gapped BLAST and PSI-BLAST: a new generation of protein database search programs.

  1997cited by this paper
• In vivo protection against Androctonus australis hector scorpion toxin and venom by immunization with a synthetic analog of toxin II.

  1997cited by this paper
• A four-disulphide-bridged toxin, with high affinity towards voltage-gated K+ channels, isolated from Heterometrus spinnifer (Scorpionidae) venom.

  1997cited by this paper
• Scorpion venoms: taking the sting out of lung disease.

  1996cited by this paper
• Toxic peptides and genes encoding toxin gamma of the Brazilian scorpions Tityus bahiensis and Tityus stigmurus.

  1996cited by this paper
• TreeView: an application to display phylogenetic trees on personal computers

  1996cited by this paper
• CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice.

  1994cited by this paper
• Diversity and endemism in tropical versus temperate scorpion communities

  1994cited by this paper
• Three-dimensional structure of natural charybdotoxin in aqueous solution by 1H-NMR. Charybdotoxin possesses a structural motif found in other scorpion toxins.

  1991cited by this paper

• Biochemical characterization of the venom of Central American scorpion Didymocentrus krausi Francke, 1978 (Diplocentridae) and its toxic effects in vivo and in vitro.

  2019cites this paper
• Classes, Databases, and Prediction Methods of Pharmaceutically and Commercially Important Cystine-Stabilized Peptides

  2018cites this paper
• Bioinformatics analysis of structure and function of Lebestatine isolated from Macrovipera venom

  2017cites this paper
• Scorpion Venom as Therapeutic Agent-Current Perspective

  2016cites this paper
• Bioinformatics-Aided Venomics

  2015cites this paper
• Scorpion Peptides: Potential Use for New Drug Development

  2013cites this paper
• Molecular diversity of Chaerilidae venom peptides reveals the dynamic evolution of scorpion venom components from Buthidae to non-Buthidae.

  2013cites this paper
• Comparative venom gland transcriptome analysis of the scorpion Lychas mucronatus reveals intraspecific toxic gene diversity and new venomous components

  2010cites this paper
• Molecular cloning and electrophysiological studies on the first K(+) channel toxin (LmKTx8) derived from scorpion Lychas mucronatus.

  2007cites this paper
• Prediction of Neurotoxins Based on Their Function and Source

  2007cites this paper
• Structure–activity relationship of an α-toxin Bs-Tx28 from scorpion (Buthus sindicus) venom suggests a new α-toxin subfamily

  2006cites this paper
• HgeTx1, the first K+-channel specific toxin characterized from the venom of the scorpion Hadrurus gertschi Soleglad.

  2006cites this paper
• Deduction of functional peptide motifs in scorpion toxins

  2006cites this paper
• Structure-activity relationship of an alpha-toxin Bs-Tx28 from scorpion (Buthus sindicus) venom suggests a new alpha-toxin subfamily.

  2006cites this paper
• SCORPION2: a database for structure-function analysis of scorpion toxins.

  2006cites this paper
• Overview of scorpion toxins specific for Na+ channels and related peptides: biodiversity, structure-function relationships and evolution.

  2005cites this paper