Overview of scorpion toxins specific for Na+ channels and related peptides: biodiversity, structure-function relationships and evolution.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Toxicon

• Publication date

  2005-12-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/J.TOXICON.2005.09.006PMID 16274721
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Amino acid sequence of toxin XI of the scorpion Buthus occitanus tunetanus. Evidence of a mutation having an important effect upon neurotoxic activity.

  2009cited by this paper
• Voltage-gated sodium channel toxins

  2007cited by this paper
• Proteomic analysis of the venom and characterization of toxins specific for Na+ - and K+ -channels from the Colombian scorpion Tityus pachyurus.

  2006cited by this paper
• β‐Scorpion toxin effects suggest electrostatic interactions in domain II of voltage‐dependent sodium channels

  2005cited by this paper
• From genome to "venome": molecular origin and evolution of the snake venom proteome inferred from phylogenetic analysis of toxin sequences and related body proteins.

  2005cited by this paper
• Anuroctoxin, a New Scorpion Toxin of the α-KTx 6 Subfamily, Is Highly Selective for Kv1.3 over IKCa1 Ion Channels of Human T Lymphocytes

  2005cited by this paper
• Molecular basis of the mammalian potency of the scorpion alpha-like toxin, BmK M1.

  2005cited by this paper
• Expression of the standard scorpion alpha-toxin AaH II and AaH II mutants leading to the identification of some key bioactive elements.

  2005cited by this paper
• A Note on the Evolution of Spider Toxins Containing the Ick-Motif

  2005cited by this paper
• Tox-Prot, the toxin protein annotation program of the Swiss-Prot protein knowledgebase.

  2005cited by this paper
• Genetic polymorphism and expression of a highly potent scorpion depressant toxin enable refinement of the effects on insect Na channels and illuminate the key role of Asn-58.

  2005cited by this paper
• Molecular interaction of delta-conotoxins with voltage-gated sodium channels.

  2005cited by this paper
• More genes or more taxa? The relative contribution of gene number and taxon number to phylogenetic accuracy.

  2005cited by this paper
• A new type of scorpion Na+-channel-toxin-like polypeptide active on K+ channels.

  2005cited by this paper
• A Spider Toxin That Induces a Typical Effect of Scorpion α-Toxins but Competes with β-Toxins on Binding to Insect Sodium Channels†

  2005cited by this paper
• A spider toxin that induces a typical effect of scorpion alpha-toxins but competes with beta-toxins on binding to insect sodium channels.

  2005cited by this paper
• Solution structure and lipid membrane partitioning of VSTx1, an inhibitor of the KvAP potassium channel.

  2005cited by this paper
• BmP09, a “Long Chain” Scorpion Peptide Blocker of BK Channels*

  2005cited by this paper
• Accurate prediction of scorpion toxin functional properties from primary structures.

  2005cited by this paper
• Common Features in the Functional Surface of Scorpion β-Toxins and Elements That Confer Specificity for Insect and Mammalian Voltage-gated Sodium Channels*

  2005influential reference
• Molecular basis of the mammalian potency of the scorpion α‐like toxin, BmK M1

  2005cited by this paper
• Pharmacological comparison of two different insect models using the scorpion alpha-like toxin BmK M1 from Buthus martensii Karsch.

  2005cited by this paper
• The Brazilian scorpion Tityus costatus Karsch: genes, peptides and function.

  2005cited by this paper
• Molecular interaction of δ‐conotoxins with voltage‐gated sodium channels

  2005cited by this paper
• Differential Phospholipid Binding by Site 3 and Site 4 Toxins

  2005cited by this paper
• Classification of scorpion toxins according to amino acid composition and sequence

  2005cited by this paper
• The depressant scorpion neurotoxin LqqIT2 selectively modulates the insect voltage-gated sodium channel.

  2005cited by this paper
• Assembling an arsenal: origin and evolution of the snake venom proteome inferred from phylogenetic analysis of toxin sequences.

  2004cited by this paper
• Molecular basis of the high insecticidal potency of scorpion alpha-toxins.

  2004cited by this paper
• Conversion of a scorpion toxin agonist into an antagonist highlights an acidic residue involved in voltage sensor trapping during activation of neuronal Na+ channels.

  2004cited by this paper
• A membrane-access mechanism of ion channel inhibition by voltage sensor toxins from spider venom

  2004cited by this paper
• Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers

  2004cited by this paper
• Molecular Basis of the High Insecticidal Potency of Scorpion α-Toxins*

  2004cited by this paper
• Molecular mechanism of scorpion neurotoxins acting on sodium channels

  2004cited by this paper
• Phylogenomic inference of protein molecular function: advances and challenges

  2004cited by this paper
• NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical β-toxin sequence but with α-like physiological activity

  2004cited by this paper
• Combinatorial interaction of scorpion toxins Lqh-2, Lqh-3, and LqhalphaIT with sodium channel receptor sites-3.

  2004cited by this paper
• NMR solution structure of Cn12, a novel peptide from the Mexican scorpion Centruroides noxius with a typical beta-toxin sequence but with alpha-like physiological activity.

  2004cited by this paper
• Purification and characterization of a new peptide with analgesic effect from the scorpion Buthus martensi Karch.

  2004cited by this paper
• Proteomics of the venom from the Amazonian scorpion Tityus cambridgei and the role of prolines on mass spectrometry analysis of toxins.

  2004cited by this paper
• Localization of the voltage-sensor toxin receptor on KvAP.

  2004cited by this paper
• Dissection of the Functional Surface of an Anti-insect Excitatory Toxin Illuminates a Putative “Hot Spot” Common to All Scorpion β-Toxins Affecting Na+ Channels*

  2004cited by this paper
• Phaiodotoxin, a novel structural class of insect-toxin isolated from the venom of the Mexican scorpion Anuroctonus phaiodactylus.

  2004cited by this paper
• Isolation, molecular cloning and functional characterization of a novel beta-toxin from the Venezuelan scorpion, Tityus zulianus.

  2004cited by this paper
• Molecular cloning and functional expression of the alpha-scorpion toxin BotIII: pivotal role of the C-terminal region for its interaction with voltage-dependent sodium channels.

  2004cited by this paper
• Diversity of folds in animal toxins acting on ion channels.

  2004cited by this paper
• Arthropod defensins illuminate the divergence of scorpion neurotoxins

  2004cited by this paper
• Conversion of a scorpion toxin agonist into an antagonist highlights an acidic residue involved in voltage sensor trapping during activation of neuronal Na+ channels

  2004cited by this paper
• Adaptive Evolution of Scorpion Sodium Channel Toxins

  2004cited by this paper
• Importance of the conserved aromatic residues in the scorpion alpha-like toxin BmK M1: the hydrophobic surface region revisited.

  2003cited by this paper
• MrBayes 3: Bayesian phylogenetic inference under mixed models

  2003cited by this paper
• Missing data, incomplete taxa, and phylogenetic accuracy.

  2003cited by this paper
• New insight on scorpion divergence inferred from comparative analysis of toxin structure, pharmacology and distribution.

  2003cited by this paper
• Primary structure and electrophysiological characterization of two almost identical isoforms of toxin from Isometrus vittatus (family: Buthidae) scorpion venom.

  2003cited by this paper
• An 'Old World' scorpion beta-toxin that recognizes both insect and mammalian sodium channels.

  2003cited by this paper
• Exploration of the functional site of a scorpion alpha-like toxin by site-directed mutagenesis.

  2003cited by this paper
• Increased taxon sampling is advantageous for phylogenetic inference.

  2002cited by this paper
• Domain 2 of Drosophila Para Voltage-Gated Sodium Channel Confers Insect Properties to a Rat Brain Channel

  2002cited by this paper
• Determination of species-specific components in the venom of Parabuthus scorpions from southern Africa using matrix-assisted laser desorption time-of-flight mass spectrometry.

  2002cited by this paper
• An overview of toxins and genes from the venom of the Asian scorpion Buthus martensi Karsch.

  2002cited by this paper
• Increased taxon sampling greatly reduces phylogenetic error.

  2002cited by this paper
• Kurtoxin, A Gating Modifier of Neuronal High- and Low-Threshold Ca Channels

  2002cited by this paper
• Cn11, the first example of a scorpion toxin that is a true blocker of Na(+) currents in crayfish neurons.

  2002cited by this paper
• SCORPION, a molecular database of scorpion toxins.

  2002cited by this paper
• A single charged surface residue modifies the activity of ikitoxin, a beta-type Na+ channel toxin from Parabuthus transvaalicus.

  2002cited by this paper
• Two new scorpion toxins that target voltage-gated Ca2+ and Na+ channels.

  2002cited by this paper
• Differential sensitivity of sodium channels from the central and peripheral nervous system to the scorpion toxins Lqh‐2 and Lqh‐3

  2002cited by this paper
• MRBAYES : Bayesian inference of phylogeny

  2001cited by this paper
• Neutralization of Gating Charges in Domain II of the Sodium Channel α Subunit Enhances Voltage-Sensor Trapping by a β-Scorpion Toxin

  2001cited by this paper
• Potassium channels: from scorpion venoms to high-resolution structure.

  2001cited by this paper
• Interaction of Scorpion α-Toxins with Cardiac Sodium Channels

  2001cited by this paper
• Resurgence of sodium channel research.

  2001cited by this paper
• Moving pieces in a proteomic puzzle: mass fingerprinting of toxic fractions from the venom of Tityus serrulatus (Scorpiones, Buthidae).

  2001cited by this paper
• MRBAYES: Bayesian inference of phylogenetic trees

  2001cited by this paper
• TOXIN EVOLUTION IN SCORPION VENOM: EVIDENCE FOR TOXIN DIVERGENCE UNDER STRONG NEGATIVE SELECTION IN LEIURUS QUINQUESTRIATUS SUBSPECIES

  2001cited by this paper
• Sequence and electrophysiological characterization of two insect‐selective excitatory toxins from the venom of the Chinese scorpion Buthus martensi

  2000cited by this paper
• Gene family evolution and homology: genomics meets phylogenetics.

  2000cited by this paper
• Scorpion α and α‐like toxins differentially interact with sodium channels in mammalian CNS and periphery

  2000cited by this paper
• Scorpion alpha and alpha-like toxins differentially interact with sodium channels in mammalian CNS and periphery.

  2000cited by this paper
• Peptides and genes coding for scorpion toxins that affect ion-channels.

  2000cited by this paper
• Purification, cDNA cloning and function assessment of BmK abT, a unique component from the Old World scorpion species

  2000cited by this paper
• Molecular mechanisms of neurotoxin action on voltage-gated sodium channels.

  2000cited by this paper
• Scorpion toxins specific for Na+-channels.

  1999cited by this paper
• Role of lysine and tryptophan residues in the biological activity of toxin VII (Ts gamma) from the scorpion Tityus serrulatus.

  1999cited by this paper
• Scorpion α‐like toxins, toxic to both mammals and insects, differentially interact with receptor site 3 on voltage‐gated sodium channels in mammals and insects

  1999cited by this paper
• The Putative Bioactive Surface of Insect-selective Scorpion Excitatory Neurotoxins*

  1999cited by this paper
• Oxidative refolding chromatography: folding of the scorpion toxin Cn5

  1999cited by this paper
• Dynamic Diversification from a Putative Common Ancestor of Scorpion Toxins Affecting Sodium, Potassium, and Chloride Channels

  1999cited by this paper
• Crystal structure of neurotoxin Ts1 from Tityus serrulatus provides insights into the specificity and toxicity of scorpion toxins.

  1999cited by this paper
• Expression and purification of the BmK M1 neurotoxin from the scorpion Buthus martensii Karsch.

  1999cited by this paper
• Inhibition of T-type voltage-gated calcium channels by a new scorpion toxin

  1998cited by this paper
• δ‐Atracotoxins from Australian funnel‐web spiders compete with scorpion α‐toxin binding on both rat brain and insect sodium channels

  1998cited by this paper
• Delta-atracotoxins from Australian funnel-web spiders compete with scorpion alpha-toxin binding on both rat brain and insect sodium channels.

  1998cited by this paper
• New toxins acting on sodium channels from the scorpion Leiurus quinquestriatus hebraeus suggest a clue to mammalian vs insect selectivity.

  1998cited by this paper
• Voltage sensor-trapping: enhanced activation of sodium channels by beta-scorpion toxin bound to the S3-S4 loop in domain II.

  1998cited by this paper
• Functional Anatomy of Scorpion Toxins Affecting Sodium Channels

  1998influential reference
• Refined electrophysiological analysis suggests that a depressant toxin is a sodium channel opener rather than a blocker.

  1997cited by this paper
• In vitro folding and functional analysis of an anti-insect selective scorpion depressant neurotoxin produced in Escherichia coli.

  1997cited by this paper
• Identification of Structural Elements of a Scorpion α-Neurotoxin Important for Receptor Site Recognition*

  1997cited by this paper
• MOLMOL: a program for display and analysis of macromolecular structures.

  1996cited by this paper

• Scorpion Venom Neurotoxins: Molecular Diversity, Mechanisms, and Drug Scaffolds

  2026cites this paper
• Scorpio fuscus venom as a promising anticancer agent against colorectal cancer.

  2026cites this paper
• Structural insights into insect-selective sodium channel toxins drive AI-enhanced biopesticide design.

  2026cites this paper
• Immunogenicity of two representative American consensus scorpion neurotoxins from the genera Tityus and Centruroides.

  2026cites this paper
• STATE OF THE ART ON THE DEVELOPMENT OF A RECOMBINANT ANTIVENOM AGAINST MEXICAN SCORPION STINGS.

  2025cites this paper
• Deciphering Scorpion Toxin-Induced Pain: Molecular Mechanisms and Ion Channel Dynamics

  2025cites this paper
• Enzymatic characterization and proteomic profiling of venoms from the medically important Androctonus species

  2025cites this paper
• Structural Determination of Bl-3, an Insecticidal Peptide from the Buthacus leptochelys Scorpion Venom

  2025cites this paper
• Molecular Diversity and Isoform Evolution in Tityus obscurus Venom: Insights from Proteomic Analysis

  2025cites this paper
• Design of antinociceptive peptide by grafting domains between scorpion β-neurotoxins.

  2025cites this paper
• The Onychomys pangenome reveals the unique molecular adaptations that confer toxin resistance

  2025cites this paper
• Ion-Channel-Targeting Scorpion Recombinant Toxin as Novel Therapeutic Agent for Breast Cancer

  2025cites this paper
• Epidemiological, clinical, biological and evolutionary profile of scorpion envenomed children under one year to 15 years in the Souss Massa region of Morocco.

  2024cites this paper
• Similar neurotoxin expression profiles of traditional Chinese scorpion medicine material between juvenile and adult Mesobuthus martensii scorpions revealed by multiple strategic proteomics.

  2024cites this paper
• Venom characterization of Venezuelan scorpion Tityus caripitensis.

  2024cites this paper
• Spider and scorpion knottins targeting voltage-gated sodium ion channels in pain signaling.

  2024cites this paper
• Unlocking nature's arsenal: Nanotechnology for targeted delivery of venom toxins in cancer therapy.

  2024cites this paper
• Purification and Molecular Characterization of a Mammalian Neurotoxin as a Pharmaceutical Tool from the Venom of Iranian Scorpion Androctonus crassicauda

  2024cites this paper
• Pharmacokinetic evaluation of a single chain antibody fragment against scorpion toxins in sheep.

  2024cites this paper
• Characterization of the coupling mechanism of scorpion β-neurotoxins on the voltage-gated sodium channel hNav1.6

  2023cites this paper
• Development of a human antibody fragment cross-neutralizing scorpion toxins.

  2023cites this paper
• CogiTx1: A novel subtilisin a inhibitor isolated from the sea anemone Condylactis gigantea belonging to the defensin 4 protein family.

  2023cites this paper
• OUTCOMES OF TREATMENT OF SNAKE AND SCORPION ENVENOMATION IN BIRDS OF PREY, WITH AND WITHOUT ANTIVENOM

  2023cites this paper
• Structural and Functional Characterization of a Novel Scorpion Toxin that Inhibits NaV1.8 via Interactions With the DI Voltage Sensor and DII Pore Module

  2022cites this paper
• Inhibitory Effect of Hemiscorpius lepturus Scorpion Venom Fractions on Tachyzoites of Toxoplasma gondii

  2022cites this paper
• Morphometric Indices and Venom Protein Profile in Different Populations of Androctonus crassicauda

  2022cites this paper
• Structural and functional studies of LaIT2, an antimicrobial and insecticidal peptide from Liocheles australasiae.

  2022cites this paper
• Venoms and Oral Cancer: A Mini-review

  2022cites this paper
• Makatoxin-3, a thermostable Nav1.7 agonist from Buthus martensii Karsch (BmK) scorpion elicits non-narcotic analgesia in inflammatory pain models.

  2022cites this paper
• Anti-Cancer Activity of Buthus occitanus Venom on Hepatocellular Carcinoma in 3D Cell Culture

  2022cites this paper
• French Scorpionism (Mainland and Oversea Territories): Narrative Review of Scorpion Species, Scorpion Venom, and Envenoming Management

  2022cites this paper
• Characterization of Four Medically Important Toxins from Centruroides huichol Scorpion Venom and Its Neutralization by a Single Recombinant Antibody Fragment

  2022cites this paper
• Scorpion crude venom induced apoptosis and structural changes of Echinococcus granulosus protoscolices

  2022cites this paper
• Peptides with Diverse Functions from Scorpion Venom: A Great Opportunity for the Treatment of a Wide Variety of Diseases

  2022cites this paper
• Modulation of hNav by Tst1, a β-toxin purified from the scorpion Tityus stigmurus.

  2022cites this paper
• Cytotoxicity and Molecular Alterations Induced by Scorpion Venom Antimicrobial Peptide Smp43 in Breast Cancer Cell Lines MDA-MB-231 and MCF-7

  2022cites this paper
• Ts17, a Tityus serrulatus β-toxin structurally related to α-scorpion toxins.

  2022cites this paper
• A Buthus martensii Karsch scorpion sting targets Nav1.7 in mice and mimics a phenotype of human chronic pain.

  2021cites this paper
• Examining the interactions scorpion venom peptides (HP1090, Meucin-13, and Meucin-18) with the receptor binding domain of the coronavirus spike protein to design a mutated therapeutic peptide

  2021cites this paper
• Anti-Cancer Effect of Moroccan Cobra Naja haje Venom and Its Fractions against Hepatocellular Carcinoma in 3D Cell Culture

  2021cites this paper
• Mass spectrometry‐based top‐down and bottom‐up approaches for proteomic analysis of the Moroccan Buthus occitanus scorpion venom

  2021cites this paper
• The venom of the scorpion Centruroides limpidus, which causes the highest number of stings in Mexico, is neutralized by two recombinant antibody fragments.

  2021cites this paper
• Characterization of Venom Components of Two Medically Important Scorpion Species, Hottentota tamulus (Fabricius, 1798) and Androctonus finitimus (Pocock, 1897)

  2021cites this paper
• Armed stem to stinger: a review of the ecological roles of scorpion weapons

  2021cites this paper
• Proteomic analysis of Red Sea Conus taeniatus venom reveals potential biological applications

  2021cites this paper
• New Insectotoxin from Tibellus Oblongus Spider Venom Presents Novel Adaptation of ICK Fold

  2021cites this paper
• Identification and Characterization of Novel Proteins from Arizona Bark Scorpion Venom That Inhibit Nav1.8, a Voltage-Gated Sodium Channel Regulator of Pain Signaling

  2021cites this paper
• Comparison of the Scorpionism Caused by Centruroides margaritatus, Tityus pachyurus and Tityus n. sp. aff. metuendus Scorpion Venoms in Colombia

  2021cites this paper
• Transcriptomic and proteomic analyses of venom glands from scorpions Liocheles australasiae, Mesobuthus martensii, and Scorpio maurus palmatus.

  2021cites this paper
• Overexpression and purification of a toxic peptide LaIT2 from Japanese scorpion, Liocheles australasiae.

  2021cites this paper
• The rapid development of the first instar telson with venom secretion highlights the remarkable survival ability of scorpions.

  2021cites this paper
• Amazonian scorpions and scorpionism: integrating toxinological, clinical, and phylogenetic data to combat a human health crisis in the world’s most diverse rainforest

  2021cites this paper
• Methionine 58 is a key residue in the modulation of BmK scorpion toxin AGP-SYPU2 activity through in silico and in vivo studies

  2020cites this paper
• Genetic and toxinological divergence among populations of Tityus trivittatus Kraepelin, 1898 (Scorpiones: Buthidae) inhabiting Paraguay and Argentina

  2020cites this paper
• ImKTx96, a peptide blocker of the Kv1.2 ion channel from the venom of the scorpion Isometrus maculates.

  2020cites this paper
• C-Terminal Amidation of Chlorotoxin Does Not Affect Tumour Cell Proliferation and Has No Effect on Toxin Cytotoxicity

  2020cites this paper
• Novel venom-based peptides (P13 and its derivative—M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGFβ signaling pathways

  2020cites this paper
• A spider-venom peptide with multi-target activity on sodium and calcium channels alleviates chronic visceral pain in a model of irritable bowel syndrome.

  2020cites this paper
• Defensive Venoms: Is Pain Sufficient for Predator Deterrence?

  2020cites this paper
• C-Terminal Amidation of Chlorotoxin Does Not Affect Tumour Cell Proliferation and Has No Effect on Toxin Cytotoxicity

  2020cites this paper
• Comparative assessment of the VH-VL and VL-VH orientations of single-chain variable fragments of scorpion toxin-neutralizing antibodies.

  2020cites this paper
• Transcriptomic and proteomic analyses of the venom and venom glands of Centruroides hirsutipalpus, a dangerous scorpion from Mexico.

  2020cites this paper
• Solution structure and functional analysis of HelaTx1: the first toxin member of the κ-KTx5 subfamily

  2020cites this paper
• Nature and applications of scorpion venom: an overview

  2020cites this paper
• Purification and characterization of a novel type of neurotoxic peptides from the venom of the Iranian scorpion Hemiscorpius lepturus

  2020cites this paper
• VENOM DIVERSITY IN THE NEOTROPICAL SCORPION GENUS TITYUS: IMPLICATIONS FOR ANTIVENOM DESIGN EMERGING FROM MOLECULAR AND IMMUNOCHEMICAL ANALYSES ACROSS ENDEMIC AREAS OF SCORPIONISM.

  2020cites this paper
• Tb1, a Neurotoxin from Tityus bahiensis Scorpion Venom, Induces Epileptic Seizures by Increasing Glutamate Release

  2020cites this paper
• Biochemical, electrophysiological and immunological characterization of the venom from Centruroides baergi, a new scorpion species of medical importance in Mexico.

  2020cites this paper
• Current Biochemical Applications and Future Prospects of Chlorotoxin in Cancer Diagnostics and Therapeutics

  2019cites this paper
• Biochemical characterization of the venom from the Mexican scorpion Centruroides ornatus, a dangerous species to humans.

  2019cites this paper
• Nontoxic fraction of scorpion venom reduces bacterial growth and inflammatory response in a mouse model of infection

  2019cites this paper
• Isolation and Characterization of Insecticidal Toxins from the Venom of the North African Scorpion, Buthacus leptochelys

  2019cites this paper
• Smp76, a Scorpine-Like Peptide Isolated from the Venom of the Scorpion Scorpio maurus palmatus, with a Potent Antiviral Activity Against Hepatitis C Virus and Dengue Virus

  2019cites this paper
• Inhibition of Tityus serrulatus venom hyaluronidase affects venom biodistribution

  2019cites this paper
• Informatics and Computational Methods in Natural Product Drug Discovery: A Review and Perspectives

  2019cites this paper
• The Dual α-Amidation System in Scorpion Venom Glands

  2019cites this paper
• Venoms of Iranian Scorpions (Arachnida, Scorpiones) and Their Potential for Drug Discovery

  2019cites this paper
• BmK AEP, an Anti-Epileptic Peptide Distinctly Affects the Gating of Brain Subtypes of Voltage-Gated Sodium Channels

  2019cites this paper
• Generation of a Broadly Cross-Neutralizing Antibody Fragment against Several Mexican Scorpion Venoms

  2019cites this paper
• Characterization, molecular modeling and phylogenetic analysis of a long mammalian neurotoxin from the venom of the Iranian scorpion Androctonus crassicauda

  2019cites this paper
• Venom Peptides with Dual Modulatory Activity on the Voltage-Gated Sodium Channel NaV1.1 Provide Novel Leads for Development of Antiepileptic Drugs.

  2019cites this paper
• Selected to survive and kill: Tityus serrulatus, the Brazilian yellow scorpion

  2019cites this paper
• Serotherapy against Voltage-Gated Sodium Channel-Targeting α-Toxins from Androctonus Scorpion Venom

  2019cites this paper
• Cytotoxic Effects of Smp24 and Smp43 Scorpion Venom Antimicrobial Peptides on Tumour and Non-tumour Cell Lines

  2019cites this paper
• Anticancer and antimicrobial activities of scorpion venoms and their peptides

  2019cites this paper
• Electrophysiological characterization of Tityus obscurus β toxin 1 (To1) on Na+-channel isoforms.

  2019cites this paper
• Insights into the binding mode and functional components of the analgesic-antitumour peptide from Buthus martensii Karsch to human voltage-gated sodium channel 1.7 based on dynamic simulation analysis

  2019cites this paper
• Venom‐gland transcriptomics and venom proteomics of the Hentz striped scorpion (Centruroides hentzi; Buthidae) reveal high toxin diversity in a harmless member of a lethal family

  2018cites this paper
• The diversity of venom components of the scorpion species Paravaejovis schwenkmeyeri (Scorpiones: Vaejovidae) revealed by transcriptome and proteome analyses

  2018cites this paper
• Selective Ligands and Drug Discovery Targeting the Voltage-Gated Sodium Channel Nav1.7.

  2018cites this paper
• Intraspecific venom variation in southern African scorpion species of the genera Parabuthus, Uroplectes and Opistophthalmus (Scorpiones: Buthidae, Scorpionidae)

  2018cites this paper
• Venom characterization of the Amazonian scorpion Tityus metuendus

  2018cites this paper
• North American scorpion species of public health importance with a reappraisal of historical epidemiology.

  2018cites this paper
• Hyaluronidase: the spreading factor of Tityus serrulatus venom

  2018cites this paper
• RK1, the first very short peptide from Buthus occitanus tunetanus inhibits tumor cell migration, proliferation and angiogenesis.

  2018cites this paper
• Anti-scorpion venom activity of Thapsia garganica methanolic extract: Histopathological and biochemical evidences.

  2018cites this paper
• Differential toxicity and venom gland gene expression in Centruroides vittatus

  2017cites this paper
• Novel trophic interaction: the scuttle fly Megaselia scalaris (Diptera: Phoridae) is a facultative parasitoid of the desert scorpion Mesobuthus eupeus mongolicus (Scorpiones: Buthidae)

  2017cites this paper
• To4, the first Tityus obscurus &bgr;‐toxin fully electrophysiologically characterized on human sodium channel isoforms

  2017cites this paper
• Oxidative stress and some biochemical alterations due to scorpion (Leiurus quinquestriatus) crude venom in rats.

  2017cites this paper