Transient receptor potential vanilloid subtype 1 depletion mediates mechanical allodynia through cellular signal alterations in small-fiber neuropathy

chin-hong chang,Ying-Shuang Chang,Yu-Lin Hsieh

Published 2021 in PAIN Reports

ABSTRACT

TRPV1, a polymodal nociceptor, depletion not only leads to thermal analgesia, but also develops mechanical allodynia through the alteration of cellular analgesia and signal in small-fiber neuropathy.

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