Comparative Effects of Volutrauma and Atelectrauma on Lung Inflammation in Experimental Acute Respiratory Distress Syndrome

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Critical Care Medicine

• Publication date

  2016-09-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1097/CCM.0000000000001721PMID 27035236PMCID PMC5105831
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Lung Inflammation Persists After 27 Hours of Protective Acute Respiratory Distress Syndrome Network Strategy and Is Concentrated in the Nondependent Lung

  2015influential reference
• Effect of Local Tidal Lung Strain on Inflammation in Normal and Lipopolysaccharide-Exposed Sheep*

  2014cited by this paper
• Early Inflammation Mainly Affects Normally and Poorly Aerated Lung in Experimental Ventilator-Induced Lung Injury*

  2014influential reference
• Ventilator-Induced Lung Injury

  2014cited by this paper
• Volutrauma, but not Atelectrauma, Induces Systemic Cytokine Production by Lung-Marginated Monocytes*

  2014cited by this paper
• High-frequency oscillation for acute respiratory distress syndrome.

  2013cited by this paper
• Update in acute respiratory distress syndrome and mechanical ventilation 2012.

  2013influential reference
• High-frequency oscillation in early acute respiratory distress syndrome.

  2013cited by this paper
• Micro-Autoradiographic Assessment of Cell Types Contributing to 2-Deoxy-2-[18F]Fluoro-d-Glucose Uptake During Ventilator-Induced and Endotoxemic Lung Injury

  2013cited by this paper
• Ventilator-induced lung injury.

  2013cited by this paper
• Effects of ventilation strategy on distribution of lung inflammatory cell activity

  2013cited by this paper
• Lung Stress and Strain During Mechanical Ventilation: Any Difference Between Statics and Dynamics?*

  2013cited by this paper
• Effects of surfactant depletion on regional pulmonary metabolic activity during mechanical ventilation.

  2011cited by this paper
• Positron emission tomography: a tool for better understanding of ventilator-induced and acute lung injury

  2011cited by this paper
• Lung regional metabolic activity and gas volume changes induced by tidal ventilation in patients with acute lung injury.

  2011cited by this paper
• Analysis of 2-[Fluorine-18]-Fluoro-2-deoxy-D-glucose uptake kinetics in PET studies of pulmonary inflammation.

  2011cited by this paper
• Ventilations-Perfusions-Lungen -szintigraphie mit der PET und 68Ga-markierten Radiopharmaka

  2010cited by this paper
• Mild Endotoxemia during Mechanical Ventilation Produces Spatially Heterogeneous Pulmonary Neutrophilic Inflammation in Sheep

  2010cited by this paper
• New and conventional strategies for lung recruitment in acute respiratory distress syndrome

  2010cited by this paper
• Animal models of acute lung injury

  2008cited by this paper
• Regional Gas Exchange and Cellular Metabolic Activity in Ventilator-induced Lung Injury

  2007cited by this paper
• Atelectasis causes alveolar injury in nonatelectatic lung regions.

  2006influential reference
• Positive end-expiratory pressure prevents lung mechanical stress caused by recruitment/derecruitment.

  2005influential reference
• High tidal volume upregulates intrapulmonary cytokines in an in vivo mouse model of ventilator-induced lung injury.

  2003cited by this paper
• Neutrophil metabolic activity but not neutrophil sequestration reflects the development of pancreatitis-associated lung injury*

  2002cited by this paper
• Computed tomography assessment of positive end-expiratory pressure-induced alveolar recruitment in patients with acute respiratory distress syndrome.

  2001cited by this paper
• What has computed tomography taught us about the acute respiratory distress syndrome?

  2001cited by this paper
• Deformation-induced injury of alveolar epithelial cells. Effect of frequency, duration, and amplitude.

  2000cited by this paper
• Effects of decreased respiratory frequency on ventilator-induced lung injury.

  2000cited by this paper
• Regional distribution of gas and tissue in acute respiratory distress syndrome. I. Consequences for lung morphology

  2000cited by this paper
• Consequences of vascular flow on lung injury induced by mechanical ventilation.

  1998cited by this paper
• Pulmonary fibrosis correlates with duration of tissue neutrophil activation.

  1998cited by this paper
• Dissociation of neutrophil emigration and metabolic activity in lobar pneumonia and bronchiectasis.

  1997cited by this paper
• In vivo measurement of neutrophil activity in experimental lung inflammation.

  1994cited by this paper
• Tidal ventilation at low airway pressures can augment lung injury.

  1994cited by this paper
• Histopathologic pulmonary changes from mechanical ventilation at high peak airway pressures.

  1991cited by this paper
• High inflation pressure pulmonary edema. Respective effects of high airway pressure, high tidal volume, and positive end-expiratory pressure.

  1988cited by this paper
• Effect of granulocyte depletion in a ventilated surfactant-depleted lung.

  1987cited by this paper
• Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data

  1983influential reference
• In Vivo Lung Lavage as an Experimental Model of the Respiratory Distress Syndrome

  1980cited by this paper
• The [18F]Fluorodeoxyglucose Method for the Measurement of Local Cerebral Glucose Utilization in Mane

  1979cited by this paper
• Differences in oxygen metabolism of phagocytosing monocytes and neutrophils.

  1978cited by this paper

• Beatmungsstrategien in der Intensivmedizin

  2026cites this paper
• Effect of individualized PEEP guided by EIT vs. conventional fixed PEEP on postoperative pulmonary complications in adult patients with preoperative cardiopulmonary dysfunction undergoing CRS/HIPEC: a randomized clinical trial

  2026cites this paper
• The potential risk of ventilator-induced lung injury from five different PEEP titration techniques in ARDS

  2025cites this paper
• Optimizing Positive End-Expiratory Pressure in Asymmetric Acute Lung Injury in a Porcine Model: The Role of Transpulmonary Pressure

  2025cites this paper
• Assessment of recruitment from CT to the bedside: challenges and future directions

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• Effect of aging on pulmonary cellular responses during mechanical ventilation

  2025cites this paper
• Imaging and pulmonary function techniques in ARDS diagnosis and management: current insights and challenges

  2025cites this paper
• Advancing predictive modeling of LPS-induced acute lung injury: A machine learning model for success rate prediction

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• The PROtective VEntilation (PROVE) Network - advancing research and collaboration in mechanical ventilation

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• Mechanical ventilation guided by driving pressure optimizes local pulmonary biomechanics in an ovine model

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• Pleural lung sliding quantification using a speckle tracking technology: A feasibility study on 30 healthy volunteers

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• Clinical evaluation of laryngeal mask airways in video-assisted thoracic surgery: a meta-analysis of randomized controlled trials

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  2024cites this paper
• Effects of different positive end-expiratory pressure titration strategies on mechanical power during ultraprotective ventilation in ARDS patients treated with veno-venous extracorporeal membrane oxygenation: A prospective interventional study.

  2023cites this paper
• Distribution of transpulmonary pressure during one-lung ventilation in pigs at different body positions

  2023influential citation
• Recruitment-to-inflation Ratio Assessed through Sequential End-expiratory Lung Volume Measurement in Acute Respiratory Distress Syndrome

  2023cites this paper
• Risk factors for ventilator-induced-lung injury develop three to five times faster after a single episode of lung injury

  2023cites this paper
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  2023cites this paper
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  2023cites this paper
• Ventilatory strategies during venovenous ECMO in ARDS: PEEPing at the elephant in the room.

  2023cites this paper
• Imaging the acute respiratory distress syndrome: past, present and future

  2022cites this paper
• Static Stretch Increases the Pro-Inflammatory Response of Rat Type 2 Alveolar Epithelial Cells to Dynamic Stretch

  2022cites this paper
• Understanding the pathophysiology of typical acute respiratory distress syndrome and severe COVID-19

  2022cites this paper
• Personalization of Mechanical Ventilation Treatment using Deep Conservative Reinforcement Learning

  2022cites this paper
• Automatic Lung Segmentation and Quantification of Aeration in Computed Tomography of the Chest Using 3D Transfer Learning

  2022cites this paper
• Unilateral acute lung injury in pig: a promising animal model

  2022cites this paper
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  2022cites this paper
• Efficacy of maintaining low-tidal volume mechanical ventilation as compared to resting lung strategy during coronary artery bypass graft cardiopulmonary bypass surgery: A post-hoc analysis of the MECANO trial.

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• Lung distribution of gas and blood volume in critically ill COVID-19 patients: a quantitative dual-energy computed tomography study

  2021cites this paper
• Ten golden rules for individualized mechanical ventilation in acute respiratory distress syndrome

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• Mechanical ventilation in COVID‐19: A physiological perspective

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• Effect of patient-ventilator asynchrony on lung and diaphragmatic injury in experimental acute respiratory distress syndrome in a porcine model.

  2021cites this paper
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  2021cites this paper
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  2021cites this paper
• Perioperative Pulmonary Atelectasis: Part I. Biology and Mechanisms.

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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
• Intraoperative ventilation strategies to prevent postoperative pulmonary complications: a network meta-analysis of randomised controlled trials.

  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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  2020cites this paper
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• Chest Sonography to Assess Lung Recruitment in Patients with Acute Respiratory Distress Syndrome

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  2020cites this paper
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  2019cites this paper
• Perioperative Lung Injury

  2019cites this paper
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  2019cites this paper
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  2019cites this paper
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  2017cites this paper
• The authors reply.

  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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  2017cites this paper
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