Hepatitis B.

Laboratory confirmation of infection as demonstrated by:  Hepatitis B surface antigen (HBsAg) positive PLUS immunoglobulin M antibody to hepatitis B core antigen (anti-HBc IgM) positive in the context of a compatible clinical history or probable exposure. OR  Loss of HBsAg within a six month period after testing HBsAg positive in the context of a compatible clinical history or probable exposure AND in the absence of recent history of Hepatitis B virus (HBV) vaccination. OR  Positive HBV DNA by polymerase chain reaction (PCR) followed by HBsAg and HBV core IgM antibody sero-conversion in the context of a compatible clinical history or probable exposure.

• Publication year

  2016

• Venue

  Journal

• Publication date

  2016-09-16

• Fields of study

  Medicine

• Identifiers
  DOI 10.1542/9781610020619-ch060PMID 1393787
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• No references are available for this paper.

• Melhora da função renal em pacientes com hepatite B crônica e doença renal crônica após a mudança para fumarato de tenofovir alafenamida: uma revisão sistemática com meta-análise de braço único

  2026cites this paper
• Hepatitis B knowledge among nursing students at Jiblah University for medical and health sciences

  2026influential citation
• Mediation Analysis of the Relationship Between Health Literacy and the French General Population's Opinions on Hepatitis B Vaccination: Representative Cross-Sectional Survey of the SLAVACO Project.

  2026influential citation
• Preserving the Poly(A) Tail: Strategies Viruses Use to ‘CYA’ (Cover Your A’s)

  2026cites this paper
• Viral Hepatitis B, C and Delta in Greenland: A National Cross‐Sectional Study

  2026cites this paper
• Development of a Novel Human Hepatoma Cell Line Supporting the Replication of a Recombinant HBV Genome with a Reporter Gene.

  2026cites this paper
• Study on Deep Vein Thrombosis Incidence and Risk Factors in Orthopedic Trauma Patients with Chronic Hepatitis B: 579 Cases Analyzed

  2026cites this paper
• People living with HIV co-infected with HBV at the Nkembo Outpatient Treatment Center, Gabon: prevalence and associated factors.

  2026cites this paper
• Healthcare system readiness to manage viral hepatitis in Viet Nam and the Philippines: results of a brief health facility assessment

  2026cites this paper
• An interpretable machine learning model for prediction of significant liver fibrosis in comorbid chronic hepatitis B and nonalcoholic fatty liver disease: a retrospective development and validation study

  2026cites this paper
• Clinical outcomes of intrahepatic cholestasis of pregnancy with versus without chronic hepatitis B: A retrospective analysis

  2026cites this paper
• Hepatitis B virus (HBV) DNA is present as both cccDNA and integrated forms in kidney tissues of HBV surface antigen-negative patients with renal cell carcinoma.

  2026cites this paper
• Kaempferol inhibits hepatitis B virus replication via ERK/FOXO1 pathway-mediated suppression of the viral core promoter.

  2026cites this paper
• Efficacy and Safety of Tenofovir Alafenamide Fumarate and Tenofovir Disoproxil Fumarate for Preventing Mother-to-Child Transmission of Hepatitis B in Treatment-Naïve mothers: An Observational Study

  2026cites this paper
• Effect of Hepatitis B virus infection during pregnancy on the risk of postpartum hemorrhage: a systematic review and meta-analysis

  2026cites this paper
• Hepatocyte–hepatic stellate cell interactions in liver fibrosis: Mechanisms and therapeutic implications

  2026cites this paper
• Association between serum HBV DNA levels and liver fibrosis in chronic hepatitis B.

  2026cites this paper
• Advancing Clinical Diagnosis Through Comparative Analysis of Machine Learning and Transformer-Based Models for Hepatitis B Detection

  2026cites this paper
• Association between HBV DNA levels and bone mineral density in antiviral-naive chronic hepatitis B patients.

  2026cites this paper
• A case report of agranulocytosis caused by acute hepatitis B virus infection

  2026cites this paper
• Association between fatty liver and risk of liver failure in patients with acute hepatitis B: a retrospective cohort study

  2026cites this paper
• Comprehensive review of lateral flow immunoassay for virus detection: From basic and nucleic acid amplification aspects

  2026cites this paper
• Preventing vertical transmission of hepatitis B in sub-Saharan Africa: protocol for a systematic review and meta-analysis on vaccination uptake and determinants among pregnant women

  2026cites this paper
• High rate of functional cure in infants with chronic hepatitis B following a definite duration of antiviral treatment.

  2026cites this paper
• Prevalence of Hepatitis B Among Migrants Living in High‐Income Countries With Low/Intermediate HBV Prevalence–A Systematic Review and Meta‐Analysis

  2026influential citation
• Association between HBV DNA Load and Bone Mineral Density at Different Sites in Middle-Aged and Elderly Patients with Chronic Hepatitis B

  2026cites this paper
• Challenges and Solutions in pgRNA Measurement: Toward Improved Monitoring of Hepatitis B Therapy.

  2026cites this paper
• Indeterminate Phase/Grey Zone of Chronic Hepatitis B: Clinical Features, Outcomes and Molecular Insights

  2026cites this paper
• Rapid and reagent-free screening of occult hepatitis B virus infection based on plasma Vis-NIR spectral pattern recognition

  2026cites this paper
• HBV genotype distribution and S gene mutations in HIV-HBV co-infected patients: insights from North India.

  2026cites this paper
• Proliferation, migration, and differentiation of circulating ILC precursors in HBV infection-associated fibrosis

  2026cites this paper
• A meta-analysis of controlled clinical trials comparing peginterferon-α plus nucleos(t)ide analogs versus peginterferon-α monotherapy for HBsAg clearance or seroconversion in patients with chronic hepatitis B

  2026cites this paper
• Early warning of hepatitis B epidemics in Henan Province, China, from 2014 to 2023 based on Baidu Index and Bayesian Structural Time Series model

  2026influential citation
• Unveiling the Hidden Reservoir: High Prevalence of Occult Hepatitis B and Associated Surface Gene Mutations in a Healthy Vietnamese Adult Cohort

  2026cites this paper
• Tenofovir exerts antiviral effects in pregnant women with chronic hepatitis B by influencing the expression of miR‐21‐5p

  2025cites this paper
• AAV-HBV mouse model replicates the intrahepatic immune landscape of chronic HBV patients at single-cell level

  2025cites this paper
• Disinformation From Within and Brandolini’s Law: A Call to Time-Consuming Action

  2025cites this paper
• Prevalence, Molecular Characterization, and Immune Status Response of Hepatitis B Virus Among Healthcare Workers in Yaoundé General Hospital, Cameroon, During May to June 2024: A Hospital‐Based Cross‐Sectional Study

  2025cites this paper
• Single-cell transcriptomic profiling reveals dysregulation of B-cell subset function in patients with chronic hepatitis B

  2025cites this paper
• Construction and validation of a nomogram prediction model for antiviral efficacy based on clinical characteristics and intestinal microflora distribution in patients with chronic hepatitis B

  2025cites this paper
• Anti-HBV treatment partially restores the dysfunction of innate immune cells and unconventional T cells during chronic HBV infection

  2025cites this paper
• Integrating infectious diseases into life course epidemiology

  2025cites this paper
• Longitudinal T1ρ quantification in chronic hepatitis B: from fibrosis staging to pegylated interferon-α therapeutic response tracking.

  2025cites this paper
• Unravelling the Hidden and Undiagnosed Cases of Hepatitis B and C Viruses among Patients Seeking Health Care for Other Viral Illness: A Cross-Sectional Study from Central India

  2025cites this paper
• Uptake of combined immunoprophylaxis for newborns exposed to hepatitis B virus in a high hepatitis B endemic rural setting in Northern Ghana

  2025cites this paper
• Predictive factors and clinical outcomes in decompensated non-cirrhotic chronic hepatitis B patients treated with entecavir or tenofovir disoproxil fumarate.

  2025cites this paper
• Fast pacing India’s fight against viral hepatitis: Targets & action points

  2025cites this paper
• Decade-Long Analysis of Hepatitis Trends Among International Travelers at Shanghai Port (2013–2023)

  2025cites this paper
• Frequency of Advanced Liver Fibrosis among Inactive Hepatitis B Virus Carriers: A Cross-Sectional Analysis

  2025cites this paper
• Distribution, Characteristics, and Natural History of Diverse Types of Indeterminate Chronic Hepatitis B: A REAL‐B Study

  2025cites this paper
• Sero-prevalence of hepatitis B virus and associated risk factors among pregnant women attending Demartino hospital, Mogadishu, Somalia

  2025cites this paper
• Nanoparticle-mediated SIRT1 inhibition suppresses M2 macrophage polarization and hepatocarcinogenesis in chronic hepatitis B

  2025cites this paper
• Immunomodulatory effect of Moringa oleifera and Phyllanthus niruri extracts on anti-HBV cytokine production by human peripheral blood mononuclear cells

  2025cites this paper
• Hepatitis B virus infection among children aged 1– 5 years of Mayurbhanj district (Odisha), India: A prospective study protocol

  2025cites this paper
• Advances in the management of hepatitis B

  2025cites this paper
• Blades and barriers: Oral vaccines for conquering cancers and warding off infectious diseases

  2025cites this paper
• Clinical Evaluation of the Progression of Liver Disease in Patients Coinfected With HBV and HDV in the Western Amazon Region of Brazil

  2025cites this paper
• PCR-Based Analysis of HBV and HCV Viral Loads and Their Impact on Liver Disease in Chronic Patients

  2025influential citation
• Beyond the liver: well-being as the bridge between fatigue and quality of life in chronic hepatitis B patients

  2025cites this paper
• Comprehensive Bibliometric Analysis of Prediction Models for HCC: Current Trends and Future Prospects

  2025cites this paper
• Near extinction of the HBV quasispecies driven by the hard selective sweep in chronic hepatitis B

  2025influential citation
• Virus-host interaction mechanisms in interferon therapy for hepatitis B virus infection: recent advances

  2025cites this paper
• Epidemiology of Hepatitis B Virus infection: Prevalence, vaccine coverage and its barriers in Katagum Local Government Area, Bauchi State Nigeria

  2025cites this paper
• Immunomodulatory and Anti-Inflammatory Properties of Honey and Bee Products

  2025cites this paper
• CRISPR/Cas13a combined with reverse transcription-multienzyme isothermal rapid amplification for hepatitis B virus RNA detection.

  2025cites this paper
• Low Hepatitis B vaccination coverage in New Delhi, India: urgent call for Universal Adult Hepatitis B vaccination

  2025cites this paper
• Sirtuin 2 inhibitor AGK2 exerts antiviral effects by inducing epigenetic suppression of hepatitis B virus covalently closed circular DNA through recruitment of repressive histone lysine methyltransferases and reduction of cccDNA

  2025cites this paper
• D-Cycloserine, a potential candidate for reducing hepatitis B virus cccDNA in vitro.

  2025cites this paper
• Enhancing diagnostic accuracy for HBV-related cirrhosis progression: predictive modeling using combined Golgi protein 73 and α1-microglobulin for the transition from nondecompensated to decompensated cirrhosis

  2025cites this paper
• Chronic hepatitis B virus infection increases the risk of kidney disease while antiviral therapy for hepatitis B virus can decrease kidney disease risk

  2025cites this paper
• Predictors of Medication Non-Adherence Among Hepatitis B Patients in South Sudan: A Health-Facility-Based Cross-Sectional Study

  2025cites this paper
• In Vitro Anti-Hepatitis B Virus Activity of Hydroxytyrosol from Lindernia ruellioides

  2025cites this paper
• Comparison of APRI, FIB-4 and fibroscan for detecting chronic liver disease severity among chronic Hepatitis B Patients in Pakistan.

  2025cites this paper
• Hepatitis B surface antigen: carcinogenesis mechanisms and clinical implications in hepatocellular carcinoma

  2025cites this paper
• The Antiviral Activity of Polyphenols

  2025cites this paper
• Impact of Hepatitis B Infection on Patient and Graft Survival After Kidney Transplantation

  2025cites this paper
• Exploration of Hepatitis B Virus Infection Dynamics through Virology-Informed Neural Network: A Novel Artificial Intelligence Approach

  2025influential citation
• Preliminary Evidence of Enhanced Immunogenicity of Hepatitis B Virus Vaccines When Co-Administered with Calcium Phosphate, Aluminum Hydroxide, and Cytosine Phospho-Guanine Oligodeoxynucleotides Combined Adjuvant in BALB/c Mice

  2025cites this paper
• A hepatitis B virus-free cccDNA-producing stable cell for antiviral screening.

  2025cites this paper
• Domestic cat hepadnavirus is detected infrequently in feline blood and liver samples submitted for diagnostic testing in Texas, USA.

  2025cites this paper
• The impact of maternal HBeAg carries status and elevated ALT values on adverse outcomes: a population-based cohort study in 198,049 pregnancies

  2025cites this paper
• HBV Recurrence Detected by HBV‐Related Serum Markers and Immune Escape Mutations in Chronic Hepatitis B Patients Following Liver Transplantation

  2025cites this paper
• Influence of Occult Hepatitis B Infection on Blood Transfusion Safety and Its Countermeasures

  2025cites this paper
• Chronic Hepatitis B Virus Infection and HLA Variations in a Greek Population

  2025cites this paper
• Hepatitis B knowledge and stigma in the United Arab Emirates

  2025influential citation
• Hepatitis B Vaccine Nonresponse and Associated Risk Factors: Insights From a Cohort Study

  2025cites this paper
• Anti-HBs Levels 18–26 Years After the Initial Hepatitis B Vaccination Series in a Low-to-Medium Prevalence Region: Is a Booster Dose or a Second Vaccine Series Necessary?

  2025influential citation
• RNF5 inhibits HBV replication by mediating caspase-3-dependent degradation of core protein

  2025cites this paper
• Blood-Borne Infection Prevention in Combat Sports: Position Statement of the Association of Ringside Physicians.

  2025cites this paper
• Hepatocyte‐Enriched miRNA‐193b‐3p Promotes Hepatitis B Virus Replication by Dual Activation of Viral Core Promoter Activity and Autophagy Induction by Targeting IGF‐1R

  2025cites this paper
• Impact of the Hepatitis B Immunization Strategy Adopted in Italy from 1991: The Results of a Seroprevalence Study on the Adult Population of Florence, Italy

  2025influential citation
• Estimated number of people infected with hepatitis B and C virus in Germany in 2013: a baseline prevalence estimate using the workbook method

  2025cites this paper
• Relationship Between Nucleos(t)ide analogue antiviral response time and prognosis in Chronic Hepatitis B: conclusions depend on baseline viral load and HBeAg status

  2025cites this paper
• Effectiveness of catch-up vaccination from 2009 to 2011 on incidence of hepatitis B in Guangzhou, China: a time series analysis

  2025influential citation
• Downregulated Expression of Serum Exosome-Derived miR-375-3p Alleviates Interface Hepatitis and Promotes Fibrosis Regression in Patients With Chronic Hepatitis B

  2025cites this paper
• Epidemic Trends and Spatial Distribution Characteristics of Hepatitis B in China: Surveillance Study

  2025influential citation
• Domestic Cat Hepadnavirus, a Hepatitis B-like Virus Associated with Feline Liver Disease.

  2025cites this paper
• RACGAP1 and MKI67 are potential prognostic biomarker in hepatocellular carcinoma caused by HBV/HCV via lactylation

  2025cites this paper
• Ultrasensitive clinical identification of hepatitis B surface antigen (HBsAg) by CRISPR-assisted nanopore sensing.

  2025cites this paper
• Genetic association studies in critically ill patients: a systematic review

  2025cites this paper