Malaria adhesins: structure and function

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Cellular Microbiology

• Publication date

  2014-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/cmi.12276PMID 24506585PMCID PMC4002501
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Red Blood Cell Invasion by Plasmodium vivax: Structural Basis for DBP Engagement of DARC

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• A quantitative assay for binding and inhibition of Plasmodium falciparum Erythrocyte Binding Antigen 175 reveals high affinity binding depends on both DBL domains.

  2014cited by this paper
• Apical membrane antigen 1 mediates apicomplexan parasite attachment but is dispensable for host cell invasion

  2013cited by this paper
• Glycan Masking of Plasmodium vivax Duffy Binding Protein for Probing Protein Binding Function and Vaccine Development

  2013cited by this paper
• De Novo Assembly of a Field Isolate Genome Reveals Novel Plasmodium vivax Erythrocyte Invasion Genes

  2013cited by this paper
• Molecular Basis for Sialic Acid-dependent Receptor Recognition by the Plasmodium falciparum Invasion Protein Erythrocyte-binding Antigen-140/BAEBL*

  2013influential reference
• Broadly neutralizing antiviral antibodies.

  2013cited by this paper
• Biochemical Analysis of the Plasmodium falciparum Erythrocyte-binding Antigen-175 (EBA175)-Glycophorin-A Interaction

  2013cited by this paper
• Whole Genome Sequencing of Field Isolates Reveals a Common Duplication of the Duffy Binding Protein Gene in Malagasy Plasmodium vivax Strains

  2013cited by this paper
• Molecular Architecture of a Complex between an Adhesion Protein from the Malaria Parasite and Intracellular Adhesion Molecule 1

  2013cited by this paper
• Structural and Biochemical Characterization of Plasmodium falciparum 12 (Pf12) Reveals a Unique Interdomain Organization and the Potential for an Antiparallel Arrangement with Pf41*

  2013cited by this paper
• Structural and Functional Basis for Inhibition of Erythrocyte Invasion by Antibodies that Target Plasmodium falciparum EBA-175

  2013cited by this paper
• Structure of the Plasmodium 6-cysteine s48/45 domain

  2012cited by this paper
• Insights into Duffy Binding-like Domains through the Crystal Structure and Function of the Merozoite Surface Protein MSPDBL2 from Plasmodium falciparum*

  2012cited by this paper
• Structural and Functional Insights into the Malaria Parasite Moving Junction Complex

  2012influential reference
• Crystal and Solution Structures of Plasmodium falciparum Erythrocyte-binding Antigen 140 Reveal Determinants of Receptor Specificity during Erythrocyte Invasion*

  2012influential reference
• Structural Basis for the ABO Blood-Group Dependence of Plasmodium falciparum Rosetting

  2012cited by this paper
• Semaphorin-7A Is an Erythrocyte Receptor for P. falciparum Merozoite-Specific TRAP Homolog, MTRAP

  2012cited by this paper
• Shape change in the receptor for gliding motility in Plasmodium sporozoites

  2012cited by this paper
• The cell biology of disease: The cellular and molecular basis for malaria parasite invasion of the human red blood cell

  2012cited by this paper
• Biochemical and Functional Analysis of Two Plasmodium falciparum Blood-Stage 6-Cys Proteins: P12 and P41

  2012cited by this paper
• Unexpected fold in the circumsporozoite protein target of malaria vaccines

  2012influential reference
• Analysis of the Conformation and Function of the Plasmodium falciparum Merozoite Proteins MTRAP and PTRAMP

  2012cited by this paper
• Malaria parasites form filamentous cell-to-cell connections during reproduction in the mosquito midgut

  2011cited by this paper
• Binding of Plasmodium merozoite proteins RON2 and AMA1 triggers commitment to invasion

  2011cited by this paper
• The malaria circumsporozoite protein has two functional domains, each with distinct roles as sporozoites journey from mosquito to mammalian host

  2011influential reference
• Dimerization of Plasmodium vivax DBP is induced upon receptor binding and drives recognition of DARC

  2011influential reference
• A role for heparan sulfate proteoglycans in Plasmodium falciparum sporozoite invasion of anopheline mosquito salivary glands

  2011cited by this paper
• Structural Characterization of the Erythrocyte Binding Domain of the Reticulocyte Binding Protein Homologue Family of Plasmodium yoelii

  2011cited by this paper
• BASIGIN is a receptor essential for erythrocyte invasion by Plasmodium falciparum

  2011cited by this paper
• The RON2-AMA1 Interaction is a Critical Step in Moving Junction-Dependent Invasion by Apicomplexan Parasites

  2011cited by this paper
• Structure of a Plasmodium falciparum PfEMP1 rosetting domain reveals a role for the N-terminal segment in heparin-mediated rosette inhibition

  2011cited by this paper
• Design and Immunogenicity of a Novel Synthetic Antigen Based on the Ligand Domain of the Plasmodium vivax Duffy Binding Protein

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• Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA

  2010cited by this paper
• Three Members of the 6-cys Protein Family of Plasmodium Play a Role in Gamete Fertility

  2010cited by this paper
• Malaria Parasite Invasion of the Mosquito Salivary Gland Requires Interaction between the Plasmodium TRAP and the Anopheles Saglin Proteins

  2009cited by this paper
• Rhoptry neck protein RON2 forms a complex with microneme protein AMA1 in Plasmodium falciparum merozoites.

  2009cited by this paper
• Adhesion of Plasmodium falciparum-infected erythrocytes to human cells: molecular mechanisms and therapeutic implications

  2009cited by this paper
• Structure of the Plasmodium falciparum Circumsporozoite Protein, a Leading Malaria Vaccine Candidate*

  2009cited by this paper
• Polymorphisms in Erythrocyte Binding Antigens 140 and 181 Affect Function and Binding but Not Receptor Specificity in Plasmodium falciparum

  2009cited by this paper
• Structural Comparison of Two CSPG-Binding DBL Domains from the VAR2CSA Protein Important in Malaria during Pregnancy

  2009cited by this paper
• Plasmodium sporozoite invasion of the mosquito salivary gland.

  2009cited by this paper
• Host-cell invasion by malaria parasites: insights from Plasmodium and Toxoplasma.

  2008cited by this paper
• Apical membrane antigen 1: a malaria vaccine candidate in review.

  2008cited by this paper
• The Structure of a Chondroitin Sulfate-binding Domain Important in Placental Malaria

  2008cited by this paper
• The Cysteine-Rich Interdomain Region from the Highly Variable Plasmodium falciparum Erythrocyte Membrane Protein-1 Exhibits a Conserved Structure

  2008cited by this paper
• Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite

  2007cited by this paper
• Plasmodium P25 and P28 Surface Proteins: Potential Transmission-Blocking Vaccines

  2007cited by this paper
• Malarial EBA-175 region VI crystallographic structure reveals a KIX-like binding interface.

  2007cited by this paper
• Mosquito Heparan Sulfate and Its Potential Role in Malaria Infection and Transmission*

  2007cited by this paper
• Heparan sulfate proteoglycans provide a signal to Plasmodium sporozoites to stop migrating and productively invade host cells.

  2007cited by this paper
• The essential mosquito-stage P25 and P28 proteins from Plasmodium form tile-like triangular prisms

  2006cited by this paper
• Structural basis for Duffy recognition by the malaria parasite Duffy-binding-like domain

  2006cited by this paper
• A Conserved Molecular Motor Drives Cell Invasion and Gliding Motility across Malaria Life Cycle Stages and Other Apicomplexan Parasites*

  2006cited by this paper
• Structure of AMA1 from Plasmodium falciparum reveals a clustering of polymorphisms that surround a conserved hydrophobic pocket.

  2005cited by this paper
• Two proteins with 6‐cys motifs are required for malarial parasites to commit to infection of the hepatocyte

  2005cited by this paper
• Crystal Structure of the Malaria Vaccine Candidate Apical Membrane Antigen 1

  2005cited by this paper
• The Anopheles gambiae gamma1 laminin directly binds the Plasmodium berghei circumsporozoite- and TRAP-related protein (CTRP).

  2005cited by this paper
• Targeted disruption of maebl in Plasmodium falciparum.

  2005cited by this paper
• The Plasmodium circumsporozoite protein is proteolytically processed during cell invasion

  2005cited by this paper
• Structural basis for the EBA-175 erythrocyte invasion pathway of the malaria parasite Plasmodium falciparum.

  2005influential reference
• Distinct Protein Classes Including Novel Merozoite Surface Antigens in Raft-like Membranes of Plasmodium falciparum*

  2005cited by this paper
• Mutational analysis of the GPI‐anchor addition sequence from the circumsporozoite protein of Plasmodium

  2005cited by this paper
• A Role for Apical Membrane Antigen 1 during Invasion of Hepatocytes by Plasmodium falciparum Sporozoites*

  2004cited by this paper
• Plasmodium sporozoite molecular cell biology.

  2004influential reference
• Crystal structure of a Fab complex formed with PfMSP1-19, the C-terminal fragment of merozoite surface protein 1 from Plasmodium falciparum: a malaria vaccine candidate.

  2003cited by this paper
• Sites of interaction between aldolase and thrombospondin-related anonymous protein in plasmodium.

  2003cited by this paper
• Band 3 is a host receptor binding merozoite surface protein 1 during the Plasmodium falciparum invasion of erythrocytes

  2003cited by this paper
• Glycophorin C is the receptor for the Plasmodium falciparum erythrocyte binding ligand PfEBP-2 (baebl).

  2003cited by this paper
• The Merozoite Surface Protein 1 Complex of Human Malaria Parasite Plasmodium falciparum

  2003influential reference
• Polymorphism in a Plasmodium falciparum Erythrocyte-binding Ligand Changes Its Receptor Specificity

  2002cited by this paper
• Genome sequence of the human malaria parasite Plasmodium falciparum

  2002cited by this paper
• MAEBL Is Essential for Malarial Sporozoite Infection of the Mosquito Salivary Gland

  2002cited by this paper
• Plasmodium falciparum MAEBL is a unique member of the ebl family.

  2002cited by this paper
• P25 and P28 proteins of the malaria ookinete surface have multiple and partially redundant functions

  2001influential reference
• A central role for P48/45 in malaria parasite male gamete fertility.

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• Migration of Plasmodium sporozoites through cells before infection.

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  2001cited by this paper
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  2000cited by this paper
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  2000cited by this paper
• Apical membrane antigen 1 plays a central role in erythrocyte invasion by Plasmodium species

  2000cited by this paper
• Targeted Disruption of the Plasmodium berghei Ctrp Gene Reveals Its Essential Role in Malaria Infection of the Vector Mosquito

  1999cited by this paper
• The PAN module: the N‐terminal domains of plasminogen and hepatocyte growth factor are homologous with the apple domains of the prekallikrein family and with a novel domain found in numerous nematode proteins

  1999cited by this paper
• The crystal structure of C-terminal merozoite surface protein 1 at 1.8 A resolution, a highly protective malaria vaccine candidate.

  1999cited by this paper
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  1999cited by this paper
• The A‐domain and the thrombospondin‐related motif of Plasmodium falciparum TRAP are implicated in the invasion process of mosquito salivary glands

  1999cited by this paper
• Conservation of a Gliding Motility and Cell Invasion Machinery in Apicomplexan Parasites

  1999cited by this paper
• Solution structure of an EGF module pair from the Plasmodium falciparum merozoite surface protein 1.

  1999cited by this paper
• Developmental selection of var gene expression in Plasmodium falciparum

  1998cited by this paper
• Antigenic variation in malaria: in situ switching, relaxed and mutually exclusive transcription of var genes during intra‐erythrocytic development in Plasmodium falciparum

  1998cited by this paper
• Anopheles stephensi salivary glands bear receptors for region I of the circumsporozoite protein of Plasmodium falciparum.

  1997cited by this paper
• TRAP is necessary for gliding motility and infectivity of plasmodium sporozoites.

  1997cited by this paper
• The Disulfide Bond Structure of Plasmodium Apical Membrane Antigen-1*

  1996cited by this paper
• Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes.

  1995cited by this paper
• Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes.

  1995cited by this paper
• Receptor and ligand domains for invasion of erythrocytes by Plasmodium falciparum.

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• Binding of Plasmodium falciparum 175-kilodalton erythrocyte binding antigen and invasion of murine erythrocytes requires N-acetylneuraminic acid but not its O-acetylated form

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• A family of erythrocyte binding proteins of malaria parasites.

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• A malaria invasion receptor, the 175-kilodalton erythrocyte binding antigen of Plasmodium falciparum recognizes the terminal Neu5Ac(alpha 2- 3)Gal- sequences of glycophorin A

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• Designing an effective malaria vaccine targeting Plasmodium vivax Duffy-binding protein.

  2023cites this paper
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• Plasmodium falciparum exploits CD44 as a co-receptor for erythrocyte invasion

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• Plasmodium falciparum exploits CD44 as a coreceptor for erythrocyte invasion

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• Inhibition of a critical malaria host-pathogen interaction by a computationally designed inhibitor targeting Plasmodium vivax DBP

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  2018cites this paper
• The Gerbich blood group system: old knowledge, new importance.

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