Emerging Roles of JmjC Domain-Containing Proteins.

No abstract is available for this paper.

• Publication year

  2015

• Venue

  International Review of Cell and Molecular Biology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/bs.ircmb.2015.07.003PMID 26404469
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Epigenetic Regulation by Lysine Demethylase 5 (KDM5) Enzymes in Cancer

  2011cited by this paper
• Hypoxia causes epigenetic gene regulation in macrophages by attenuating Jumonji histone demethylase activity.

  2011cited by this paper
• KDM2b/JHDM1b, an H3K36me2-specific demethylase, is required for initiation and maintenance of acute myeloid leukemia.

  2011cited by this paper
• Epigenetic gene regulation by plant Jumonji group of histone demethylase.

  2011cited by this paper
• Reversible histone methylation regulates brain gene expression and behavior.

  2011cited by this paper
• Plant homeodomain fingers form a helping hand for transcription

  2011cited by this paper
• JmjC-domain-containing histone demethylases of the JMJD1B type as putative precursors of endogenous DSIP.

  2011cited by this paper
• Structure and Function of Histone H3 Lysine 9 Methyltransferases and Demethylases

  2011cited by this paper
• JmjC enzyme KDM2A is a regulator of rRNA transcription in response to starvation

  2010cited by this paper
• Phylogenetic detection of numerous gene duplications shared by animals, fungi and plants

  2010cited by this paper
• KIAA1718 is a histone demethylase that erases repressive histone methyl marks

  2010cited by this paper
• Crystal structure of the 2-oxoglutarate- and Fe(II)-dependent lysyl hydroxylase JMJD6.

  2010cited by this paper
• Histone demethylase KDM5A is an integral part of the core Notch-RBP-J repressor complex.

  2010cited by this paper
• Regulation of H3K27me3 and H3K4me3 during early porcine embryonic development

  2010cited by this paper
• JMJ14, a JmjC domain protein, is required for RNA silencing and cell-to-cell movement of an RNA silencing signal in Arabidopsis.

  2010cited by this paper
• PHF8 Mediates Histone H4 Lysine 20 Demethylation Events Involved in Cell Cycle Progression

  2010cited by this paper
• Dual-specificity histone demethylase KIAA1718 (KDM7A) regulates neural differentiation through FGF4

  2010cited by this paper
• Regulation of mouse steroidogenesis by WHISTLE and JMJD1C through histone methylation balance

  2010cited by this paper
• Structural insights into a novel histone demethylase PHF8

  2010cited by this paper
• The histone demethylase UTX enables RB-dependent cell fate control.

  2010cited by this paper
• Tumor suppression by the histone demethylase UTX

  2010cited by this paper
• Reversal of histone methylation: biochemical and molecular mechanisms of histone demethylases.

  2010cited by this paper
• Features of the PHF8/KIAA1718 histone demethylase

  2010cited by this paper
• Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases

  2010cited by this paper
• PHF8 is a histone H3K9me2 demethylase regulating rRNA synthesis

  2010cited by this paper
• The XLMR gene PHF8 encodes a histone H4K20/H3K9 demethylase and regulates zebrafish brain and craniofacial development

  2010cited by this paper
• The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation

  2010cited by this paper
• UTX mediates demethylation of H3K27me3 at muscle-specific genes during myogenesis

  2010cited by this paper
• Structural insights into histone lysine demethylation.

  2010cited by this paper
• Crystal structure of the PHF8 Jumonji domain, an N ε‐methyl lysine demethylase

  2010cited by this paper
• KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development.

  2010cited by this paper
• The H3K27me3 Demethylase dUTX Is a Suppressor of Notch- and Rb-Dependent Tumors in Drosophila

  2010cited by this paper
• Histone demethylases in development and disease.

  2010cited by this paper
• Interaction of JMJD6 with single-stranded RNA

  2010cited by this paper
• Epigenetic regulation of cancer growth by histone demethylases

  2010cited by this paper
• Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans

  2010cited by this paper
• JMJ14 is an H3K4 demethylase regulating flowering time in Arabidopsis

  2010cited by this paper
• Conserved antagonism between JMJD2A/KDM4A and HP1γ during cell cycle progression.

  2010cited by this paper
• Crosstalk between histone modifications maintains the developmental pattern of gene expression on a tissue-specific locus

  2010cited by this paper
• PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation

  2010cited by this paper
• Recognition of Histone H3K4 Trimethylation by the Plant Homeodomain of PHF2 Modulates Histone Demethylation*

  2010cited by this paper
• KDM8, a H3K36me2 histone demethylase that acts in the cyclin A1 coding region to regulate cancer cell proliferation

  2010cited by this paper
• Analysis of Jmjd6 Cellular Localization and Testing for Its Involvement in Histone Demethylation

  2010cited by this paper
• Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS.

  2009cited by this paper
• The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence.

  2009cited by this paper
• Jmjd6 Catalyses Lysyl-Hydroxylation of U2AF65, a Protein Associated with RNA Splicing

  2009cited by this paper
• Regulation of NF-κB by NSD1/FBXL11-dependent reversible lysine methylation of p65

  2009cited by this paper
• Identification and characterization of demethylase JMJD1A as a gene upregulated in the human cellular response to hypoxia

  2009cited by this paper
• Histone modifying enzymes: structures, mechanisms, and specificities.

  2009cited by this paper
• Identification of non-histone substrates for JMJD2A-C histone demethylases.

  2009cited by this paper
• Jmjd3 contributes to the control of gene expression in LPS-activated macrophages

  2009cited by this paper
• Validation-based insertional mutagenesis identifies lysine demethylase FBXL11 as a negative regulator of NFκB

  2009cited by this paper
• A Jumonji (Jarid2) Protein Complex Represses cyclin D1 Expression by Methylation of Histone H3-K9*

  2009cited by this paper
• Regulation of the Histone Demethylase JMJD1A by Hypoxia-Inducible Factor 1α Enhances Hypoxic Gene Expression and Tumor Growth

  2009cited by this paper
• Sex-Specific Expression of the X-Linked Histone Demethylase Gene Jarid1c in Brain

  2008cited by this paper
• The Histone Demethylase KDM5b/JARID1b Plays a Role in Cell Fate Decisions by Blocking Terminal Differentiation

  2008cited by this paper
• KDM2A represses transcription of centromeric satellite repeats and maintains the heterochromatic state

  2008cited by this paper
• The Histone Demethylases JMJD1A and JMJD2B Are Transcriptional Targets of Hypoxia-inducible Factor HIF*

  2008cited by this paper
• Members of a family of JmjC domain-containing oncoproteins immortalize embryonic fibroblasts via a JmjC domain-dependent process

  2008cited by this paper
• Heterochromatin protein 1a stimulates histone H3 lysine 36 demethylation by the Drosophila KDM4A demethylase.

  2008cited by this paper
• Repression of Smad3 activity by histone demethylase SMCX/JARID1C.

  2008cited by this paper
• Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease.

  2008cited by this paper
• The emerging functions of histone demethylases.

  2008cited by this paper
• Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha.

  2008cited by this paper
• Mechanisms involved in the regulation of histone lysine demethylases.

  2008cited by this paper
• SigWin-detector: a Grid-enabled workflow for discovering enriched windows of genomic features related to DNA sequences

  2008cited by this paper
• Comparative analysis of JmjC domain-containing proteins reveals the potential histone demethylases in Arabidopsis and rice.

  2008cited by this paper
• Sex-Specific Differences in Expression of Histone Demethylases Utx and Uty in Mouse Brain and Neurons

  2008cited by this paper
• LSD1: oxidative chemistry for multifaceted functions in chromatin regulation.

  2008cited by this paper
• The JmjC Domain Histone Demethylase Ndy1 Regulates Redox Homeostasis and Protects Cells from Oxidative Stress

  2008cited by this paper
• Genome-wide analysis of the H3K4 histone demethylase RBP2 reveals a transcriptional program controlling differentiation.

  2008cited by this paper
• Genomic structure and expression of Jmjd6 and evolutionary analysis in the context of related JmjC domain containing proteins

  2008cited by this paper
• A novel mutation in JARID1C/SMCX in a patient with autism spectrum disorder (ASD)

  2008cited by this paper
• Evolutionary history of histone demethylase families: distinct evolutionary patterns suggest functional divergence

  2008cited by this paper
• Hypoxia upregulates the histone demethylase JMJD1A via HIF-1.

  2008cited by this paper
• Mutations in JARID1C are associated with X-linked mental retardation, short stature and hyperreflexia

  2008cited by this paper
• Modulation of brassinosteroid-regulated gene expression by jumonji domain-containing proteins ELF6 and REF6 in Arabidopsis

  2008cited by this paper
• Rice jmjC domain-containing gene JMJ706 encodes H3K9 demethylase required for floral organ development

  2008cited by this paper
• Control of differentiation in a self-renewing mammalian tissue by the histone demethylase JMJD3.

  2008cited by this paper
• JMJD6 Is a Histone Arginine Demethylase

  2007cited by this paper
• PTIP Associates with MLL3- and MLL4-containing Histone H3 Lysine 4 Methyltransferase Complex*♦

  2007cited by this paper
• The retinoblastoma binding protein RBP2 is an H3K4 demethylase.

  2007cited by this paper
• The Histone Demethylase, Jmjd1a, Interacts With the Myocardin Factors to Regulate SMC Differentiation Marker Gene Expression

  2007cited by this paper
• Regulation of histone methylation by demethylimination and demethylation

  2007cited by this paper
• JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes

  2007cited by this paper
• Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

  2007cited by this paper
• Histone demethylase JHDM2A is critical for Tnp1 and Prm1 transcription and spermatogenesis

  2007cited by this paper
• UTX and JMJD3 are histone H3K27 demethylases involved in HOX gene regulation and development

  2007cited by this paper
• Structure and Mechanism of Lysine-specific Demethylase Enzymes*

  2007cited by this paper
• Physical and functional association of a trimethyl H3K4 demethylase and Ring6a/MBLR, a polycomb-like protein.

  2007cited by this paper
• Histone lysine demethylases: emerging roles in development, physiology and disease

  2007cited by this paper
• RBP2 belongs to a family of demethylases, specific for tri-and dimethylated lysine 4 on histone 3.

  2007cited by this paper
• The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth.

  2007cited by this paper
• Interaction of Epe1 With the Heterochromatin Assembly Pathway in Schizosaccharomyces pombe

  2007cited by this paper
• JMJD3 is a histone H3K27 demethylase

  2007cited by this paper
• Functional Analysis of the Transcription Repressor PLU-1/JARID1B

  2007cited by this paper
• Two Saccharomyces cerevisiae JmjC Domain Proteins Demethylate Histone H3 Lys36 in Transcribed Regions to Promote Elongation*♦

  2007cited by this paper
• Identification of JmjC domain-containing UTX and JMJD3 as histone H3 lysine 27 demethylases

  2007cited by this paper
• The X-linked mental retardation gene SMCX/JARID1C defines a family of histone H3 lysine 4 demethylases.

  2007cited by this paper
• The histone H3 lysine-27 demethylase Jmjd3 links inflammation to inhibition of polycomb-mediated gene silencing.

  2007cited by this paper

• Histone demethylation by JMJ family genes: insights into plant growth and adaptation

  2025cites this paper
• The SlJMJ15, a Putative Histone Demethylase Gene, Acts as a Negative Regulator of Drought Tolerance in Tomato

  2025cites this paper
• Functional characterization of grass carp (Ctenopharyngodon idella) jmjd8 Gene in the anti-GCRV Immune response.

  2025cites this paper
• Intracellular growth of Chlamydia trachomatis leads to global histone hypermethylation by impairing demethylation

  2025cites this paper
• Histone demethylase JMJ713 interaction with JMJ708 modulating H3K36me2, enhances rice heat tolerance through promoting hydrogen peroxide scavenging.

  2024cites this paper
• Review and new insights into the catalytic structural domains of the Fe(ll) and 2-Oxoglutarate families.

  2024cites this paper
• Sex chromosome-encoded protein homologs: current progress and open questions

  2024cites this paper
• KDM4B mutations in human cancers

  2024cites this paper
• Epigenome-metabolism nexus in the retina: implications for aging and disease.

  2024cites this paper
• Epigenetic changes in shear‐stressed endothelial cells

  2024cites this paper
• H3K27 demethylase SsJMJ4 negatively regulates drought-stress responses in sugarcane.

  2024cites this paper
• EGLN3 attenuates gastric cancer cell malignant characteristics by inhibiting JMJD8/NF-κB signalling activation independent of hydroxylase activity

  2024cites this paper
• Epigenetic modulation of antitumor immunity and immunotherapy response in breast cancer: biological mechanisms and clinical implications

  2024cites this paper
• 2-oxoglutarate-dependent Dioxygenases (2-OGDDs) as Oxygen Sensors: Their Importance in Health and Disease.

  2024cites this paper
• Effect of histone modifications on fruit ripening.

  2024cites this paper
• Comprehensive exploration of isocitrate dehydrogenase (IDH) mutations: Tumorigenesis, drug discovery, and covalent inhibitor advances.

  2024cites this paper
• Jumonji domain-containing protein RIOX2 is overexpressed and associated with worse survival outcomes in prostate cancers

  2023cites this paper
• OsJMJ718, a histone demethylase gene, positively regulates seed germination in rice.

  2023cites this paper
• Epigenetic remodelling under hypoxia.

  2023cites this paper
• MicroRNA-Mediated Regulation of Histone-Modifying Enzymes in Cancer: Mechanisms and Therapeutic Implications

  2023cites this paper
• The role of epigenetic methylation/demethylation in the regulation of retinal photoreceptors

  2023cites this paper
• Stabilization of nuclear β‐catenin by inhibiting KDM2A mediates cerebral ischemic tolerance

  2023cites this paper
• Histone demethylase MaJMJ15 is involved in the regulation of postharvest banana fruit ripening.

  2023cites this paper
• Evolutionary adaptation of the Polycomb repressive complex 2

  2022cites this paper
• Phylogenomic and Evolutionary Analyses Reveal Diversifications of SET-Domain Proteins in Fungi

  2022cites this paper
• Genetics and epigenetics in conventional chondrosarcoma with focus on non-coding RNAs.

  2022cites this paper
• Combined hypoxia hypercapnia delays apoptosis and maintains CD34 cell surface antigen

  2022cites this paper
• JmjC Family of Histone Demethylases Form Nuclear Condensates

  2022cites this paper
• Emerging Immunohistochemical Biomarkers for Myeloid Neoplasms.

  2022cites this paper
• H3K36 demethylase JMJ710 negatively regulates drought tolerance by suppressing MYB48-1 expression in rice.

  2022cites this paper
• Identification of the upstream regulators of KDM5B in gastric cancer.

  2022cites this paper
• Secondary Metabolite Gene Regulation in Mycotoxigenic Fusarium Species: A Focus on Chromatin

  2022cites this paper
• Mitochondrial sirtuins at the crossroads of energy metabolism and oncogenic transformation

  2021cites this paper
• JMJD8 Promotes Malignant Progression of Lung Cancer by Maintaining EGFR Stability and EGFR/PI3K/AKT Pathway Activation

  2021cites this paper
• Epigenetic regulation of adipogenesis by histone-modifying enzymes.

  2021cites this paper
• The JmjC-domain protein NO66/RIOX-1 affects the balance between proliferation and maturation in acute myeloid leukemia.

  2021cites this paper
• How Protein Methylation Regulates Steroid Receptor Function

  2021cites this paper
• Ironing out mechanisms of iron homeostasis and disorders of iron deficiency.

  2021cites this paper
• Epithelial-mesenchymal transition: Insights into nickel-induced lung diseases.

  2021cites this paper
• KDM6A, a histone demethylase, regulates stress hematopoiesis and early B-cell differentiation.

  2021cites this paper
• Metabolo-epigenetics: the interplay of metabolism and epigenetics during early germ cells development

  2021cites this paper
• AZFa candidate gene UTY and its X homologue UTX are expressed in human germ cells

  2021cites this paper
• Genome-wide identification, evolution of histone lysine demethylases (KDM) genes and their expression during gonadal development in Nile tilapia.

  2021cites this paper
• Genome-wide identification, classification and expression analysis of the JmjC domain-containing histone demethylase gene family in Jatropha curcas L.

  2021cites this paper
• Genome-wide identi cation, classi cation and expression analysis of the JmjC domain-containing histone demethylase gene family in Jatropha curcas L

  2021cites this paper
• The Role Of Histone Demethylase Kdm6a In Mouse Coronavirus Infection

  2021cites this paper
• The role of Kabuki Syndrome genes KMT2D and KDM6A in development: Analysis in Human sequencing data and compared to mice and zebrafish

  2020cites this paper
• Modular arrangements of sequence motifs determine the functional diversity of KDM proteins

  2020cites this paper
• Metabolic and Redox Regulation of Cardiovascular Stem Cell Biology and Pathology

  2020cites this paper
• Estrogen Induces Selective Transcription of Caveolin1 Variants in Human Breast Cancer through Estrogen Responsive Element-Dependent Mechanisms

  2020cites this paper
• The role of KMT2D and KDM6A in cardiac development: A cross-species analysis in humans, mice, and zebrafish

  2020cites this paper
• LY75 Ablation Mediates Mesenchymal-Epithelial Transition (MET) in Epithelial Ovarian Cancer (EOC) Cells Associated with DNA Methylation Alterations and Suppression of the Wnt/β-Catenin Pathway

  2020cites this paper
• Inflammation-induced JMJD2D promotes colitis recovery and colon tumorigenesis by activating Hedgehog signaling

  2020cites this paper
• KMT2C/D COMPASS complex-associated diseases [KCDCOM-ADs]: an emerging class of congenital regulopathies

  2020cites this paper
• Cellular Senescence

  2019influential citation
• Response Kinetics and Clinical Benefits of Nonintensive AML Therapies in the Absence of Morphologic Response.

  2019cites this paper
• DOT1L: a key target in normal chromatin remodelling and in mixed-lineage leukaemia treatment

  2019cites this paper
• DNA demethylation is a driver for chick retina regeneration

  2019cites this paper
• The Role of Protein Lysine Methylation in the Regulation of Protein Function: Looking Beyond the Histone Code

  2019cites this paper
• Evidence of a Demethylase-Independent Role for the H3K4-Specific Histone Demethylases in Aspergillus nidulans and Fusarium graminearum Secondary Metabolism

  2019cites this paper
• Metabolic Plasticity and Epithelial-Mesenchymal Transition

  2019cites this paper
• The histone demethylase KDM5 controls developmental timing in Drosophila by promoting prothoracic gland endocycles

  2019cites this paper
• Rewriting the Script: The Story of Vitamin C and the Epigenome

  2019cites this paper
• Decreased Nuclear Ascorbate Accumulation Accompanied with Altered Genomic Methylation Pattern in Fibroblasts from Arterial Tortuosity Syndrome Patients

  2019cites this paper
• INCURVATA11 and CUPULIFORMIS2 Are Redundant Genes That Encode Epigenetic Machinery Components in Arabidopsis

  2018cites this paper
• Epigenetics: an alternative pathway in GISTs tumorigenesis Minireview

  2018cites this paper
• Patent highlights October-November 2017.

  2018cites this paper
• Jumonji C Demethylases in Cellular Senescence

  2018influential citation
• KDM2A/B lysine demethylases and their alternative isoforms in development and disease

  2018cites this paper
• KDM5B demethylates H3K4 to recruit XRCC1 and promote chemoresistance

  2018cites this paper
• Mitochondria and Hypoxia: Metabolic Crosstalk in Cell-Fate Decisions.

  2018cites this paper
• The JmjN domain as a dimerization interface and a targeted inhibitor of KDM4 demethylase activity

  2018cites this paper
• Chemical and Biochemical Perspectives of Protein Lysine Methylation.

  2018cites this paper
• JMJD8 is a novel endoplasmic reticulum protein with a JmjC domain

  2017cites this paper
• DNA and Histone Methylation in Hematopoietic Malignancy

  2017cites this paper
• Epigenetics in multiple myeloma: From mechanisms to therapy.

  2017cites this paper
• Ascorbate Alleviates Fe Deficiency-Induced Stress in Cotton (Gossypium hirsutum) by Modulating ABA Levels

  2017cites this paper
• SF-KDM 2 A binds to ribosomal RNA gene promoter , reduces H 4 K 20 me 3 level , and elevates ribosomal RNA transcription in breast cancer cells

  2017cites this paper
• Molecular Mechanisms of Apical Periodontitis: Emerging Role of Epigenetic Regulators.

  2017cites this paper
• SF-KDM2A binds to ribosomal RNA gene promoter, reduces H4K20me3 level, and elevates ribosomal RNA transcription in breast cancer cells.

  2017cites this paper
• Intensive herbicide use has selected for constitutively elevated levels of stress-responsive mRNAs and proteins in multiple herbicide-resistant Avena fatua L.

  2017cites this paper
• Design and evaluation of 1,7-naphthyridones as novel KDM5 inhibitors.

  2016cites this paper
• Isocitrate dehydrogenase mutations in myeloid malignancies

  2016cites this paper