Membrane-associated guanylate kinase-like properties of beta-subunits required for modulation of voltage-dependent Ca2+ channels.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  2004-05-04

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1073/PNAS.0306665101PMID 15100405PMCID PMC406488
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Distinctive modulatory effects of five human auxiliary beta2 subunit splice variants on L-type calcium channel gating.

  2003cited by this paper
• The Voltage-dependent Calcium Channel β Subunit Contains Two Stable Interacting Domains*

  2003cited by this paper
• Novel functional properties of Ca2+ channel β subunits revealed by their expression in adult rat heart cells

  2002cited by this paper
• Role of the beta(2) subunit of voltage-dependent calcium channels in the retinal outer plexiform layer.

  2002cited by this paper
• Ionic channels of excitable membranes

  2001cited by this paper
• Structure of the SH3-guanylate kinase module from PSD-95 suggests a mechanism for regulated assembly of MAGUK scaffolding proteins.

  2001cited by this paper
• Structural characterization of the intramolecular interaction between the SH3 and guanylate kinase domains of PSD-95.

  2001cited by this paper
• Structure and regulation of voltage-gated Ca2+ channels.

  2000cited by this paper
• An Intramolecular Interaction between Src Homology 3 Domain and Guanylate Kinase-Like Domain Required for Channel Clustering by Postsynaptic Density-95/SAP90

  2000cited by this paper
• hCASK and hDlg Associate in Epithelia, and Their Src Homology 3 and Guanylate Kinase Domains Participate in Both Intramolecular and Intermolecular Interactions*

  2000cited by this paper
• A New β Subtype-specific Interaction in α1ASubunit Controls P/Q-type Ca2+ Channel Activation*

  1999cited by this paper
• Complexes of the alpha1C and beta subunits generate the necessary signal for membrane targeting of class C L-type calcium channels.

  1999cited by this paper
• Complexes of the α1C and β Subunits Generate the Necessary Signal for Membrane Targeting of Class C L-type Calcium Channels*

  1999cited by this paper
• Modelling of a voltage‐dependent Ca2+ channel β subunit as a basis for understanding its functional properties

  1999cited by this paper
• A new beta subtype-specific interaction in alpha1A subunit controls P/Q-type Ca2+ channel activation.

  1999cited by this paper
• Identification of an Intramolecular Interaction between the SH3 and Guanylate Kinase Domains of PSD-95*

  1999cited by this paper
• Mechanism of Auxiliary Subunit Modulation of Neuronal α1E Calcium Channels

  1998cited by this paper
• Structures and functions of calcium channel beta subunits.

  1998cited by this paper
• Structures and Functions of Calcium Channel β Subunits

  1998cited by this paper
• Facilitation by the β2a subunit of pore openings in cardiac Ca2+ channels

  1998cited by this paper
• Subunit interaction sites in voltage-dependent Ca2+ channels: role in channel function.

  1998cited by this paper
• A β4 Isoform-specific Interaction Site in the Carboxyl-terminal Region of the Voltage-dependent Ca2+ Channel α1A Subunit*

  1998cited by this paper
• Direct interaction of Gβγ with a C-terminal Gβγ-binding domain of the Ca2+ channel α1 subunit is responsible for channel inhibition by G protein-coupled receptors

  1997cited by this paper
• Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors.

  1997cited by this paper
• A Xenopus oocyte beta subunit: evidence for a role in the assembly/expression of voltage-gated calcium channels that is separate from its role as a regulatory subunit.

  1997cited by this paper
• The beta subunit increases Ca2+ currents and gating charge movements of human cardiac L-type Ca2+ channels.

  1996cited by this paper
• Cell signalling: MAGUK magic.

  1996cited by this paper
• Dlg protein is required for junction structure, cell polarity, and proliferation control in Drosophila epithelia

  1996cited by this paper
• Absence of the beta subunit (cchb1) of the skeletal muscle dihydropyridine receptor alters expression of the alpha 1 subunit and eliminates excitation-contraction coupling.

  1996cited by this paper
• Absence of the β subunit (cchb1) of the skeletal muscle dihydropyridine receptor alters expression of the α1 subunit and eliminates excitation-contraction coupling

  1996cited by this paper
• Roles of a Membrane-localized βSubunit in the Formation and Targeting of Functional L-type Ca2+ Channels (*)

  1995cited by this paper
• Modification of Ca2+ channel activity by deletions at the carboxyl terminus of the cardiac alpha 1 subunit.

  1994cited by this paper
• Calcium channel beta-subunit binds to a conserved motif in the I-II cytoplasmic linker of the alpha 1-subunit.

  1994cited by this paper
• Ca2+ channel regulation by a conserved beta subunit domain.

  1994cited by this paper
• Calcium channel β-subunit binds to a conserved motif in the I–II cytoplasmic linker of the α1-subunit

  1994cited by this paper
• Ca2+ channel regulation by a conserved β subunit domain

  1994cited by this paper
• Potentiation by the beta subunit of the ratio of the ionic current to the charge movement in the cardiac calcium channel.

  1993cited by this paper
• Cloning and expression of a cardiac/brain beta subunit of the L-type calcium channel.

  1992cited by this paper
• Heterologous regulation of the cardiac Ca2+ channel alpha 1 subunit by skeletal muscle beta and gamma subunits. Implications for the structure of cardiac L-type Ca2+ channels.

  1991cited by this paper
• The roles of the subunits in the function of the calcium channel.

  1991cited by this paper
• Calcium channels, stores, and oscillations.

  1990cited by this paper
• Pdz Proteins Organize Minireview Synaptic Signaling Pathways

  year unknowncited by this paper

• CaV2.1 α1 subunit motifs that control presynaptic CaV2.1 subtype abundance are distinct from CaV2.1 preference

  2023cites this paper
• CaV2.1 α1 subunit motifs that control presynaptic CaV2.1 subtype abundance are distinct from CaV2.1 preference

  2023cites this paper
• β subunits of voltage-gated calcium channels in cardiovascular diseases

  2023cites this paper
• Selective posttranslational inhibition of CaVβ1-associated voltage-dependent calcium channels with a functionalized nanobody

  2022cites this paper
• Adrenergic Regulation of Calcium Channels in the Heart.

  2021cites this paper
• Adrenergic CaV1.2 Activation via Rad Phosphorylation Converges at α1C I-II Loop.

  2020cites this paper
• A homozygous missense variant in CACNB4 encoding the auxiliary calcium channel beta4 subunit causes a severe neurodevelopmental disorder and impairs channel and non-channel functions

  2020cites this paper
• Molecular characterization of a voltage-gated calcium channel and its potential role in the acaricidal action of scopoletin against Tetranychus cinnabarinus.

  2020cites this paper
• Role of a conserved glutamine in the function of voltage-gated Ca2+ channels revealed by a mutation in human CACNA1D

  2018cites this paper
• Regulation of voltage-gated calcium channels Cav1.2

  2017cites this paper
• Densin-180 Controls the Trafficking and Signaling of L-Type Voltage-Gated Cav1.2 Ca2+ Channels at Excitatory Synapses

  2017cites this paper
• Down-regulation of the Wnt/β-catenin signaling pathway by Cacnb4

  2017cites this paper
• Le rôle de Cavβ4 dans la prolifération cellulaire et la régulation génique

  2016influential citation
• The mammalian skeletal muscle DHPR has larger Ca2+ conductance and is phylogenetically ancient to the early ray-finned fish sterlet (Acipenser ruthenus)

  2016cites this paper
• Cloning and characterization of mersacidin like bacteriocin from Bacillus licheniformis MKU3 in Escherichia coli

  2016cites this paper
• Intramolecular ex vivo Fluorescence Resonance Energy Transfer (FRET) of Dihydropyridine Receptor (DHPR) β1a Subunit Reveals Conformational Change Induced by RYR1 in Mouse Skeletal Myotubes

  2015cites this paper
• Alternative Splicing Generates a Novel Truncated Cav1.2 Channel in Neonatal Rat Heart*

  2015cites this paper
• Novel approaches to examine the regulation of voltage-gated calcium channels in the heart.

  2015cites this paper
• Forskolin Regulates L-Type Calcium Channel through Interaction between Actinin 4 and β3 Subunit in Osteoblasts

  2015cites this paper
• The Cavβ1a subunit regulates gene expression and suppresses myogenin in muscle progenitor cells

  2014cites this paper
• Structure-function of proteins interacting with the α1 pore-forming subunit of high-voltage-activated calcium channels

  2014cites this paper
• Ion channel remodeling in vascular smooth muscle during hypertension: Implications for novel therapeutic approaches.

  2013cites this paper
• Structure and function of the β subunit of voltage-gated Ca²⁺ channels.

  2013cites this paper
• Structure and function of the β subunit of voltage-gated Ca 2+ channels

  2013cites this paper
• Regulation of voltage-dependent calcium channels by RGK proteins.

  2013cites this paper
• Molecular architecture of Ca2+ channel complexes organized by CaVβ subunits in presynaptic active zones

  2013cites this paper
• Calmodulin-dependent protein kinase II: linking heart failure and arrhythmias.

  2012cites this paper
• Bimolecular fluorescence complementation and targeted biotinylation provide insight into the topology of the skeletal muscle Ca2+ channel β1a subunit

  2012cites this paper
• Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy

  2012cites this paper
• CACNA1A mutations with clinical relevance in migraine affect Cav2.1 channel regulation by G proteins and SNAREs

  2011cites this paper
• Guanylate kinase domains of the MAGUK family scaffold proteins as specific phospho‐protein‐binding modules

  2011cites this paper
• The dynamic architecture of photoreceptor ribbon synapses: Cytoskeletal, extracellular matrix, and intramembrane proteins

  2011cites this paper
• Homodimerization of the Src Homology 3 Domain of the Calcium Channel β-Subunit Drives Dynamin-dependent Endocytosis*

  2011cites this paper
• Long term regulation of cardiac L-type calcium channel by small G proteins.

  2011cites this paper
• Trafficking and stability of voltage-gated calcium channels

  2011cites this paper
• Mechanism of auxiliary β‐subunit‐mediated membrane targeting of L‐type (CaV1.2) channels

  2011cites this paper
• The ß subunit of voltage-gated Ca2+ channels.

  2010cites this paper
• Anion-Sensitive Regions of L-Type CaV1.2 Calcium Channels Expressed in HEK293 Cells

  2010cites this paper
• BIN1 Localizes the L-Type Calcium Channel to Cardiac T-Tubules

  2010cites this paper
• Rem, a member of the RGK GTPases, inhibits recombinant CaV1.2 channels using multiple mechanisms that require distinct conformations of the GTPase

  2010cites this paper
• Dynamic interactions between L-type voltage-sensitive calcium channel Cav1.2 subunits and ahnak in osteoblastic cells.

  2009cites this paper
• Arachidonic acid inhibition of L-type calcium (CaV1.3b) channels varies with accessory CaVβ subunits

  2009cites this paper
• Defective Survival of Naive CD8+ T Lymphocytes in the absence of β3 regulatory subunit of Cav channels

  2009cites this paper
• A CaV1.1 Ca2+ channel splice variant with high conductance and voltage-sensitivity alters EC coupling in developing skeletal muscle.

  2009cites this paper
• Organization and dynamics of PDZ-domain-related supramodules in the postsynaptic density

  2009cites this paper
• Functional dissection of the intramolecular Src homology 3‐guanylate kinase domain coupling in voltage‐gated Ca2+ channel β‐subunits

  2009cites this paper
• Association of the T-Type Cav3.2 (α1H) VSCC with the Auxiliary α2δ1 Subunit in MLO-Y4 Cells

  2009cites this paper
• Determinants of the voltage dependence of G protein modulation within calcium channel β subunits

  2008cites this paper
• The guanylate kinase domain of the β-subunit of voltage-gated calcium channels suffices to modulate gating

  2008cites this paper
• The Best Disease-Linked Cl− Channel hBest1 Regulates CaV1 (L-type) Ca2+ Channels via src-Homology-Binding Domains

  2008cites this paper
• Mechanisms of presynaptic CaV2.2 (N-type) modulation.

  2008cites this paper
• Regulation of Presynaptic Calcium Channels

  2008cites this paper
• Presynaptic calcium channels: structure, regulators, and blockers.

  2008cites this paper
• The HOOK-Domain Between the SH3- and the GK-Domains of CaVβ Subunits Contains Key Determinants Controlling Calcium Channel Inactivation

  2007cites this paper
• Molecular evolution of the MAGUK family in metazoan genomes

  2007cites this paper
• Bridging the myoplasmic gap: recent developments in skeletal muscle excitation–contraction coupling

  2007cites this paper
• Functional modularity of the beta-subunit of voltage-gated Ca2+ channels.

  2007cites this paper
• The secret lives of voltage sensors

  2007cites this paper
• Voltage-gated ion channels and gating modifier toxins.

  2007cites this paper
• Antisense oligonucleotide against the Ca channel beta subunit decreases L-type Ca current in rat ventricular myocytes.

  2007cites this paper
• Computer modeling of siRNA knockdown effects indicates an essential role of the Ca2+ channel α2δ-1 subunit in cardiac excitation–contraction coupling

  2007cites this paper
• Functional Modularity of the b-Subunit of Voltage-Gated Ca 21 Channels

  2007cites this paper
• Multiplicity of protein interactions and functions of the voltage-gated calcium channel beta-subunit.

  2007cites this paper
• Protein Kinase G Phosphorylates Cav1.2 α1c and β2 Subunits

  2007cites this paper
• Computer modeling of siRNA knockdown effects indicates an essential role of the Ca2+ channel alpha2delta-1 subunit in cardiac excitation-contraction coupling.

  2007cites this paper
• Protein Kinase G Phosphorylates Ca v 1.2 (cid:1) 1c and (cid:2) 2 Subunits

  2007cites this paper
• Ahnak, a new player in beta-adrenergic regulation of the cardiac L-type Ca2+ channel.

  2007cites this paper
• Functional Expression and Inactivation of L-type Ca2+ Currents During Murine Heart Development -Implications for Cardiac Ca2+ Homeostasis

  2007cites this paper
• Ca2+ currents in cardiac myocytes: Old story, new insights.

  2006cites this paper
• Voltage-gated calcium channels and idiopathic generalized epilepsies.

  2006cites this paper
• Regulation of Maximal Open Probability Is a Separable Function of Cavβ Subunit in L-type Ca2+ Channel, Dependent on NH2 Terminus of α1C (Cav1.2α)

  2006influential citation
• Two PEST‐like motifs regulate Ca2+/calpain‐mediated cleavage of the CaVβ3 subunit and provide important determinants for neuronal Ca2+ channel activity

  2006cites this paper
• Phosphorylation sites on calcium channel alpha1 and beta subunits regulate ERK-dependent modulation of neuronal N-type calcium channels.

  2006cites this paper
• Remodeled cardiac calcium channels.

  2006cites this paper
• Analysis of the complex between Ca2+ channel beta-subunit and the Rem GTPase.

  2006cites this paper
• Analysis of the Complex between Ca2+ Channel β-Subunit and the Rem GTPase*

  2006cites this paper
• Phosphorylation sites on calcium channel α1 and β subunits regulate ERK-dependent modulation of neuronal N-type calcium channels

  2006cites this paper
• Ahnak, a new player in β -adrenergic regulation of the cardiac L-type Ca 2+ channel

  2006cites this paper
• The α1S N-terminus is not essential for bi-directional coupling with RyR1

  2005cites this paper
• Structure de la sous-unité β du canal calcique : la place du β-interaction domain

  2005cites this paper
• Role of β Subunits in Voltage-Gated Calcium Channel Functions

  2005cites this paper
• Unique modulation of L-type Ca2+ channels by short auxiliary beta1d subunit present in cardiac muscle.

  2005cites this paper
• Membrane-associated guanylate kinases regulate adhesion and plasticity at cell junctions.

  2005cites this paper
• Essential Cavβ modulatory properties are AID-independent

  2005cites this paper
• A dynamic alpha-beta inter-subunit agonist signaling complex is a novel feedback mechanism for regulating L-type Ca2+ channel opening.

  2005cites this paper
• Voltage-gated sodium and calcium channels in nerve, muscle, and heart

  2005cites this paper
• A single CaVβ can reconstitute both trafficking and macroscopic conductance of voltage‐dependent calcium channels

  2005cites this paper
• [Structure of the calcium channel beta subunit: the place of the beta-interaction domain].

  2005cites this paper
• Direct inhibition of the interaction between alpha-interaction domain and beta-interaction domain of voltage-dependent Ca2+ channels by Gem.

  2005cites this paper
• Essential Ca(V)beta modulatory properties are AID-independent.

  2005cites this paper
• Overview of Molecular Relationships in the Voltage-Gated Ion Channel Superfamily

  2005cites this paper
• A dynamic α‐β inter‐subunit agonist signaling complex is a novel feedback mechanism for regulating L‐type Ca2+ channel opening

  2005cites this paper
• New short splice variants of the human cardiac Cavbeta2 subunit: redefining the major functional motifs implemented in modulation of the Cav1.2 channel.

  2004cites this paper
• Blocking the L-type Ca2+ channel with a gem: a paradigm for a more specific Ca2+ channel blocker.

  2004cites this paper
• The VGL-Chanome: A Protein Superfamily Specialized for Electrical Signaling and Ionic Homeostasis

  2004cites this paper
• Arachidonic acid inhibition of L-type calcium (Ca V 1.3b) channels varies with accessory Ca V (cid:3) subunits

  year unknowncites this paper