Inflammatory roles of P-selectin.

No abstract is available for this paper.

• Publication year

  1993

• Venue

  Journal of Clinical Investigation

• Publication date

  1993-08-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1172/JCI116623PMID 7688760PMCID PMC294887
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• In vivo neutralization of P-selectin protects feline heart and endothelium in myocardial ischemia and reperfusion injury.

  1993cited by this paper
• Neutrophil migration across monolayers of cytokine-prestimulated endothelial cells: a role for platelet-activating factor and IL-8

  1992cited by this paper
• Characterization of GMP-140 (P-selectin) as a circulating plasma protein

  1992cited by this paper
• CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesion

  1992cited by this paper
• Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons.

  1992cited by this paper
• Leukocyte accumulation promoting fibrin deposition is mediated in vivo by P-selectin on adherent platelets

  1992cited by this paper
• GMP-140 (P-selectin) inhibits human neutrophil activation by lipopolysaccharide: analysis by proton magnetic resonance spectroscopy.

  1992cited by this paper
• The glycoprotease of Pasteurella haemolytica A1 eliminates binding of myeloid cells to P-selectin but not to E-selectin.

  1992cited by this paper
• Neutrophil-dependent acute lung injury. Requirement for P-selectin (GMP-140).

  1992cited by this paper
• Integrins: versatility, modulation, and signaling in cell adhesion.

  1992cited by this paper
• Selectins: interpreters of cell-specific carbohydrate information during inflammation.

  1992cited by this paper
• Selectins and other mammalian sialic acid-binding lectins.

  1992cited by this paper
• Identification of a specific glycoprotein ligand for P-selectin (CD62) on myeloid cells

  1992cited by this paper
• Endothelial cell interactions with granulocytes: tethering and signaling molecules.

  1992cited by this paper
• P-selectin and E-selectin. Distinct but overlapping leukocyte ligand specificities.

  1992cited by this paper
• Lectin domain peptides from selectins interact with both cell surface ligands and Ca2+ ions.

  1992cited by this paper
• Cytotoxic T-lymphocyte activation involves a cascade of signalling and adhesion events

  1992cited by this paper
• Leukocyte-endothelial cell interactions.

  1992cited by this paper
• Structural study of the sugar chains of human leukocyte cell adhesion molecules CD11/CD18.

  1991cited by this paper
• Activation of LFA-1 through a Ca2(+)-dependent epitope stimulates lymphocyte adhesion

  1991cited by this paper
• Coexpression of GMP-140 and PAF by endothelium stimulated by histamine or thrombin: a juxtacrine system for adhesion and activation of neutrophils

  1991cited by this paper
• Endothelial-leukocyte adhesion molecule 1 stimulates the adhesive activity of leukocyte integrin CR3 (CD11b/CD18, Mac-1, alpha m beta 2) on human neutrophils

  1991cited by this paper
• Multiple elevations of cytosolic-free Ca2+ in human neutrophils: initiation by adherence receptors of the integrin family

  1991cited by this paper
• GMP-140 binds to a glycoprotein receptor on human neutrophils: evidence for a lectin-like interaction

  1991cited by this paper
• Role of endothelial leukocyte adhesion molecule-1 and platelet-activating factor in neutrophil adherence to IL-1-prestimulated endothelial cells. Endothelial leukocyte adhesion molecule-1-mediated CD18 activation.

  1991cited by this paper
• Cytokine-activated human endothelial monolayers support enhanced neutrophil transmigration via a mechanism involving both endothelial-leukocyte adhesion molecule-1 and intercellular adhesion molecule-1.

  1991cited by this paper
• GMP-140 binding to neutrophils is inhibited by sulfated glycans.

  1991cited by this paper
• Leukocyte adhesion molecule-1 (LAM-1, L-selectin) interacts with an inducible endothelial cell ligand to support leukocyte adhesion.

  1991cited by this paper
• CD62/P-selectin recognition of myeloid and tumor cell sulfatides.

  1991cited by this paper
• Adhesion protein GMP140 inhibits superoxide anion release by human neutrophils.

  1991cited by this paper
• Calcium signaling capacity of the CD11b/CD18 integrin on human neutrophils.

  1991cited by this paper
• The neutrophil selectin LECAM-1 presents carbohydrate ligands to the vascular selectins ELAM-1 and GMP-140.

  1991cited by this paper
• Oxidatively fragmented phosphatidylcholines activate human neutrophils through the receptor for platelet-activating factor.

  1991cited by this paper
• Prevention of activated neutrophil adhesion to endothelium by soluble adhesion protein GMP140.

  1990cited by this paper
• Human neutrophil adherence to laminin in vitro. Evidence for a distinct neutrophil integrin receptor for laminin

  1990cited by this paper
• Identification of a human peripheral lymph node homing receptor: a rapidly down-regulated adhesion molecule.

  1990cited by this paper
• Endothelial cell-associated platelet-activating factor: a novel mechanism for signaling intercellular adhesion

  1990cited by this paper
• Tumor necrosis factor-induced degranulation in adherent human neutrophils is dependent on CD11b/CD18-integrin-triggered oscillations of cytosolic free Ca2+.

  1990cited by this paper
• Rapid neutrophil adhesion to activated endothelium mediated by GMP-140

  1990cited by this paper
• Thrombin‐Treated Endothelium Primes Neutrophil Functions: Inhibition by Platelet‐Activating Factor Receptor Antagonists

  1989cited by this paper
• The regulation of platelet-activating factor production in endothelial cells. The role of calcium and protein kinase C.

  1989cited by this paper
• Cloning of GMP-140, a granule membrane protein of platelets and endothelium: sequence similarity to proteins involved in cell adhesion and inflammation.

  1989cited by this paper
• Effect of tumor necrosis factor and granulocyte/macrophage colony-stimulating factor on neutrophil degranulation.

  1989cited by this paper
• Platelet-activating factor primes neutrophil responses to agonists: role in promoting neutrophil-mediated endothelial damage.

  1988cited by this paper
• Neutrophil adherence to human endothelium in vitro occurs by CDw18 (Mo1, MAC-1/LFA-1/GP 150,95) glycoprotein-dependent and -independent mechanisms.

  1988cited by this paper
• Production of platelet-activating factor by stimulated human polymorphonuclear leukocytes. Correlation of synthesis with release, functional events, and leukotriene B4 metabolism.

  1987cited by this paper
• Spreading of human neutrophils is immediately preceded by a large increase in cytoplasmic free calcium.

  1986cited by this paper
• Leukotrienes C4 and D4 stimulate human endothelial cells to synthesize platelet-activating factor and bind neutrophils.

  1986cited by this paper
• Supported planar membranes in studies of cell-cell recognition in the immune system.

  1986cited by this paper
• Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro.

  1985cited by this paper
• Membrane complement receptor type three (CR3) has lectin-like properties analogous to bovine conglutinin as functions as a receptor for zymosan and rabbit erythrocytes as well as a receptor for iC3b.

  1985cited by this paper
• Functional and metabolic activity of granulocytes from patients with adult respiratory distress syndrome. Evidence for activated neutrophils in the pulmonary circulation.

  1983cited by this paper
• Lipid monolayer-coated solid surfaces do not perturb the lateral motion and distribution of C3b receptors on neutrophils

  1982cited by this paper
• Phospholipid vesicle formation and transmembrane protein incorporation using octyl glucoside.

  1981cited by this paper
• Monoclonal antibody covalently coupled with fatty acid. A reagent for in vitro liposome targeting.

  1980cited by this paper

• The Platelet-Specific Gene Signature in the Immunoglobulin G4-Related Disease Transcriptome

  2025cites this paper
• By activating endothelium histone H4 mediates oleic acid-induced acute respiratory distress syndrome

  2025cites this paper
• Fucoidan: A marine-derived polysaccharide with therapeutic potential in atherosclerotic cardiovascular diseases: A review.

  2025cites this paper
• Differential platelet protein release profiles in community-acquired pneumonia and COVID-19

  2025cites this paper
• Microcapsules based on biological macromolecules for intestinal health: A review.

  2024cites this paper
• Understanding, assessing and treating immune, endothelial and haemostasis dysfunctions in bacterial sepsis

  2024cites this paper
• Is Endothelial Activation a Critical Event in Thrombotic Thrombocytopenic Purpura?

  2023cites this paper
• Heparin, Heparan Sulphate and Sepsis: Potential New Options for Treatment

  2023cites this paper
• Profiling the Murine Acute Phase and Inflammatory Responses to African Snake Venom: An Approach to Inform Acute Snakebite Pathology

  2022influential citation
• Massive expansion of P-selectin genes in two Venerida species, Sinonovacula constricta and Mercenaria mercenaria: evidence from comparative genomics of Bivalvia

  2022cites this paper
• P-Selectin is a Critical Factor for Platelet-Mediated Protection on Restraint Stress-Induced Gastrointestinal Injury in Mice

  2022cites this paper
• Programmed prodrug breaking the feedback regulation of P-selectin in plaque inflammation for atherosclerotic therapy.

  2022cites this paper
• Glycoconjugates: Synthesis, Functional Studies, and Therapeutic Developments.

  2022cites this paper
• Elevated vascular transformation blood biomarkers in Long-COVID indicate angiogenesis as a key pathophysiological mechanism

  2022cites this paper
• Redox Control of Integrin-Mediated Hepatic Inflammation in Systemic Autoimmunity

  2021cites this paper
• Pinaverium Bromide Attenuates Lipopolysaccharide-Induced Excessive Systemic Inflammation via Inhibiting Neutrophil Priming

  2021cites this paper
• Assessment of Platelet Thrombus Formation under Flow Conditions in Adult Patients with COVID-19: An Observational Study

  2021cites this paper
• Fucoidan for cardiovascular application and the factors mediating its activities.

  2021cites this paper
• Sulfonated Amphiphilic Poly(α)glutamate Amine—A Potential siRNA Nanocarrier for the Treatment of Both Chemo-Sensitive and Chemo-Resistant Glioblastoma Tumors

  2021cites this paper
• Selectins—The Two Dr. Jekyll and Mr. Hyde Faces of Adhesion Molecules—A Review

  2020cites this paper
• Apr 27, 2021 Erythrocyte, platelet, serum ferritin, and p-selectin pathophysiology implicated in severe hypercoagulation and vascular

  2020cites this paper
• Erythrocyte, Platelet, Serum Ferritin, and P-Selectin Pathophysiology Implicated in Severe Hypercoagulation and Vascular Complications in COVID-19

  2020cites this paper
• Covid-19: The Rollercoaster of Fibrin(Ogen), D-Dimer, Von Willebrand Factor, P-Selectin and Their Interactions with Endothelial Cells, Platelets and Erythrocytes

  2020cites this paper
• Type of the Paper: Review COVID-19: the rollercoaster of fibrin(ogen), D-dimer, von Willebrand Factor, P-selectin and their interactions with endothelial cells, platelets and erythrocytes

  2020cites this paper
• Prospective evaluation of host biomarkers other than interferon gamma in QuantiFERON Plus supernatants as candidates for the diagnosis of tuberculosis in symptomatic individuals.

  2019cites this paper
• Gliclazide Prevents 5-FU-Induced Oral Mucositis by Reducing Oxidative Stress, Inflammation, and P-Selectin Adhesion Molecules

  2019cites this paper
• Postprandial activation of leukocyte‐endothelium interaction by fatty acids in the visceral adipose tissue microcirculation

  2019cites this paper
• Investigational drugs in phase II clinical trials for acute coronary syndromes

  2019cites this paper
• Identification of Rare Lewis Oligosaccharide Conformers in Aqueous Solution Using Enhanced Sampling Molecular Dynamics.

  2018cites this paper
• The Potential of the Quick Detection of Selectins Using Raman Spectroscopy to Discriminate Lung Cancer Patients from Healthy Subjects

  2018cites this paper
• Changements phénotypiques des cellules endothéliales irradiées au cours du développement des lésions radiques pulmonaires

  2017cites this paper
• Development and application of an enhanced sampling molecular dynamics method to the conformational exploration of biologically relevant molecules

  2017cites this paper
• E-selectin inhibition with GMI-1271 decreases venous thrombosis without profoundly affecting tail vein bleeding in a mouse model

  2017cites this paper
• Mitogen-Activated Protein Kinase Signal Integrin Binding to ICAM-1 Through a 2 βTethering on E-Selectin Activates

  2017cites this paper
• Pulmonary endothelial activation caused by extracellular histones contributes to neutrophil activation in acute respiratory distress syndrome

  2016cites this paper
• Aspects diagnostiques et thérapeutiques du modèle d'ischémie - reperfusion mésentérique

  2016cites this paper
• Changes in Endothelial Markers during a Summer Ultra-Endurance Road Cycling Event in the Heat

  2016cites this paper
• Viscoelasticity and Ultrastructure in Coagulation and Inflammation: Two Diverse Techniques, One Conclusion

  2015cites this paper
• Selectins: initiators of leucocyte adhesion and signalling at the vascular wall.

  2015cites this paper
• Spatiotemporal Expression Dynamics of Selectins Govern the Sequential Extravasation of Neutrophils and Monocytes in the Acute Inflammatory Response

  2015cites this paper
• Cellular Adhesion in Inflammation

  2014cites this paper
• Sequential priming of neutrophils

  2014cites this paper
• Decreased tissue factor expression with increased CD11b upregulation on elastin-based biomaterial coatings.

  2014cites this paper
• Examining the Regulation of Inflammation through CD200 and CD200R Following Spinal Cord Injury

  2013cites this paper
• rolling and signaling under flow Separable requirements for cytoplasmic domain of PSGL-1 in leukocyte

  2013cites this paper
• Molecular imaging of inflammation in inflammatory bowel disease with a clinically translatable dual-selectin-targeted US contrast agent: comparison with FDG PET/CT in a mouse model.

  2013cites this paper
• to cultured endothelial cells Exogenous xanthine promotes neutrophil adherence

  2013cites this paper
• Extracellular Stimuli to Support Maximal Adhesion of Human Neutrophils 2 Activation and Acts Cooperatively with β M α Intermediate State of P-selectin Binding to P-selectin Glycoprotein Ligand-1 Induces an

  2013cites this paper
• The microcirculation in adipose tissue inflammation

  2013cites this paper
• Leukocyte Response to Elastin-Like Polypeptide Coatings

  2013cites this paper
• A peptide nanofibrous indicator for eye-detectable cancer cell identification.

  2013cites this paper
• Mitochondrial function in sepsis - Temporal evolvement of respiratory capacity in human blood cells

  2013cites this paper
• Platelet‐activating factor receptor plays a role in the pathogenesis of graft‐versus‐host disease by regulating leukocyte recruitment, tissue injury, and lethality

  2012cites this paper
• Factor V Leiden and Inflammation

  2012cites this paper
• Proteína c activada y polimorfismo genético en la sepsis grave

  2012cites this paper
• Vascular Adhesion Molecules and Inflammation

  2012cites this paper
• Thrombosis 7 Plts : Platelets MPs : Microparticles MVs : Microvesicles

  2012cites this paper
• Quantification and monitoring of inflammation in murine inflammatory bowel disease with targeted contrast-enhanced US.

  2012cites this paper
• Death due to crush injuries in a compactor truck: vitality assessment by immunohistochemistry

  2012cites this paper
• Innate immunity and coagulation

  2011cites this paper
• UNIVERSIDAD CENTRAL DEL ECUADOR INSTITUTO SUPERIOR DE POSTGRADO POSTGRADO DE EMERGENCIAS Y DESASTRES

  2011cites this paper
• Pharmacology and clinical applications of human recombinant antithrombin

  2010cites this paper
• HETEROTYPIC INTERACTIONS ENABLED BY POLARIZED NEUTROPHIL MICRODOMAINS MEDIATE THROMBO-INFLAMMATORY INJURY

  2009cites this paper
• Mechanisms responsible for homocysteine mediated damage to human endothelial cells : the role of oxidative stress in atherogenesis

  2009cites this paper
• PAPEL DE LA ACTIVACIÓN PLAQUETARIA Y LEUCOCITARIA EN LA PATOGENIA DE LA TROMBOSIS EN LA TROMBOCITEMIA ESENCIAL

  2009cites this paper
• Gastrointestinal absorption of heparins

  2009cites this paper
• Reduktion des Reperfusionsschadens am Schweineherz durch retrograde koronar-venöse Transfektion mit VEGF

  2009cites this paper
• A review of pulmonary coagulopathy in acute lung injury, acute respiratory distress syndrome and pneumonia

  2009cites this paper
• THEMED SECTION: ENDOTHELIUM IN PHARMACOLOGY REVIEW Role of nitroso radicals as drug targets in circulatory shock

  2009cites this paper
• Is Familial Mediterranean Fever a thrombotic disease or not?

  2008cites this paper
• The vessel wall and its interactions.

  2008cites this paper
• Separable requirements for cytoplasmic domain of PSGL-1 in leukocyte rolling and signaling under flow.

  2008cites this paper
• Immunohistochemical analysis of P-Selectin as a possible marker of vitality in human cutaneous wounds.

  2008cites this paper
• Radiation-Guided P-Selectin Antibody Targeted to Lung Cancer

  2008cites this paper
• Induction of platelet white blood cell (WBC) aggregate formation by platelets and WBCs in red blood cell units

  2008cites this paper
• The anti-inflammatory effects of heparin and related compounds.

  2008cites this paper
• Purified polysaccharide from Ginkgo biloba leaves inhibits P-selectin-mediated leucocyte adhesion and inflammation

  2008cites this paper
• Role of lysophosphatidylcholine (LPC) in atherosclerosis.

  2007cites this paper
• Trousseau's syndrome: multiple definitions and multiple mechanisms.

  2007cites this paper
• Effects of Aprotinin on Gene Expression and Protein Synthesis After Ischemia and Reperfusion in Rats

  2007cites this paper
• P-selectin Cross-links PSGL-1 and Enhances Neutrophil Adhesion to Fibrinogen and ICAM-1 in a Src Kinase-Dependent, but GPCR-Independent Mechanism

  2007cites this paper
• P-selectin glycoprotein ligand-1 (PSGL-1)

  2007cites this paper
• Selectin, Platelet Plays a Critical Role in Granulocyte Access to the Pregnant Mouse Uterus Under Physiological and Pathological Conditions1

  2007cites this paper
• In vivo Analyse der zellulären und molekularen Mechanismen der arteriellen und venösen Thrombose in der Maus

  2007cites this paper
• Comparative effects of nebivolol and metoprolol on oxidative stress, insulin resistance, plasma adiponectin and soluble P-selectin levels in hypertensive patients

  2006cites this paper
• Group B streptococcus isolates from septic patients and healthy carriers differentially activate platelet signaling cascades

  2006cites this paper
• 5-Lipoxygenase modulates colitis through the regulation of adhesion molecule expression and neutrophil migration

  2005cites this paper
• Effects of phospholipid-coated extracorporeal circuits on clinical outcome parameters and systemic inflammatory response in coronary artery bypass graft patients.

  2005cites this paper
• Sepsis: Definiciones y Aspectos Fisiopatológicos

  2005cites this paper
• Soluble adhesion molecules ICAM-1, VCAM-1, P-selectin in children with Helicobacter pylori infection.

  2005cites this paper
• Effect of ischaemic preconditioning on regional release of inflammatory markers.

  2005cites this paper
• Shock, inflammation and PARP.

  2005cites this paper
• Neutrophils in the innate immune response.

  2005cites this paper
• Role of poly(ADP-ribose) glycohydrolase (PARG) in shock, ischemia and reperfusion.

  2005cites this paper
• Peroxisome proliferator-activated receptors gamma ligands and ischemia and reperfusion injury.

  2004cites this paper
• , receptors and endogenous PAF synthesis VEGF-mediated endothelial P-selectin translocation : role of VEGF

  2004cites this paper
• Activated protein C reduces stress‐induced gastric mucosal injury in rats by inhibiting the endothelial cell injury

  2004cites this paper
• Decreased Serum Levels of P-Selectin and Eosinophil Cationic Protein in Patients with Mild Asthma after Inhaled Salbutamol

  2004cites this paper
• Inflammation and glomerular injury

  2004cites this paper
• Platelet-endothelial cell adhesion molecule-1 gene polymorphism and its soluble level are associated with severe coronary artery stenosis in Chinese Singaporean.

  2004cites this paper