Evidence for the involvement of fibroblast growth factor 10 in lipofibroblast formation during embryonic lung development

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Development

• Publication date

  2015-12-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1242/dev.109173PMID 26511927PMCID PMC4712831
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Fibroblast growth factor signaling in myofibroblasts differs from lipofibroblasts during alveolar septation in mice.

  2015influential reference
• Fgf10-positive cells represent a progenitor cell population during lung development and postnatally

  2014cited by this paper
• Roles of FGFs as Adipokines in Adipose Tissue Development, Remodeling, and Metabolism

  2014cited by this paper
• Type 2 alveolar cells are stem cells in adult lung.

  2013cited by this paper
• Characterization of the adipocyte cellular lineage in vivo

  2013cited by this paper
• Characterization of a Novel Fibroblast Growth Factor 10 (Fgf10) Knock-In Mouse Line to Target Mesenchymal Progenitors during Embryonic Development

  2012cited by this paper
• Thy-1 signals through PPARγ to promote lipofibroblast differentiation in the developing lung.

  2012cited by this paper
• A PPARγ-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis

  2012cited by this paper
• The vascular endothelium of the adipose tissue gives rise to both white and brown fat cells.

  2012cited by this paper
• Contrasting Expression of Canonical Wnt Signaling Reporters TOPGAL, BATGAL and Axin2LacZ during Murine Lung Development and Repair

  2011cited by this paper
• Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury.

  2011cited by this paper
• Signaling by FGFR2b controls the regenerative capacity of adult mouse incisors

  2010cited by this paper
• Effect of maternal food restriction on fetal rat lung lipid differentiation program

  2009cited by this paper
• Peroxisome proliferator-activated receptor-gamma ligands induce heme oxygenase-1 in lung fibroblasts by a PPARgamma-independent, glutathione-dependent mechanism.

  2009cited by this paper
• Wnt11/Fgfr1b cross-talk modulates the fate of cells in palate development.

  2008cited by this paper
• Terminal end bud maintenance in mammary gland is dependent upon FGFR2b signaling.

  2008cited by this paper
• Reversal of Nicotine-Induced Alveolar Lipofibroblast-to-Myofibroblast Transdifferentiation by Stimulants of Parathyroid Hormone-Related Protein Signaling

  2007cited by this paper
• Hyperoxia augments pulmonary lipofibroblast-to-myofibroblast transdifferentiation

  2007cited by this paper
• Role of PPARs and Retinoid X Receptors in the Regulation of Lung Maturation and Development

  2007cited by this paper
• Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development.

  2007cited by this paper
• EVIDENCE FOR THE PRESENCE OF LIPOFIBROBLASTS IN HUMAN LUNG

  2006cited by this paper
• Role of Fgf10 in cell proliferation in white adipose tissue.

  2006cited by this paper
• Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung.

  2006cited by this paper
• Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage

  2005cited by this paper
• Roles of fibroblast growth factor 10 (Fgf10) in adipogenesis in vivo.

  2004cited by this paper
• Arrested pulmonary alveolar cytodifferentiation and defective surfactant synthesis in mice missing the gene for parathyroid hormone‐related protein

  2004cited by this paper
• THE ROLE OF FIBROBLAST TRANSDIFFERENTIATION IN LUNG EPITHELIAL CELL PROLIFERATION, DIFFERENTIATION, AND REPAIR IN VITRO

  2003cited by this paper
• Trade, Human Rights and an Alternative World Order: The role of civil society

  2002cited by this paper
• Role of adipocyte differentiation-related protein in surfactant phospholipid synthesis by type II cells.

  2002cited by this paper
• Requirement of fibroblast growth factor 10 in development of white adipose tissue.

  2002cited by this paper
• Role of FGF10/FGFR2b signaling during mammary gland development in the mouse embryo.

  2002cited by this paper
• The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm.

  2001cited by this paper
• An important role for the IIIb isoform of fibroblast growth factor receptor 2 (FGFR2) in mesenchymal-epithelial signalling during mouse organogenesis.

  2000cited by this paper
• Fgf10 is essential for limb and lung formation

  1999cited by this paper
• Fibroblast growth factor interactions in the developing lung.

  1999cited by this paper
• FGF-7 modulates ureteric bud growth and nephron number in the developing kidney.

  1999cited by this paper
• Fibroblast growth factor 10 (FGF10) and branching morphogenesis in the embryonic mouse lung.

  1997cited by this paper
• The pulmonary lipofibroblast (lipid interstitial cell) and its contributions to alveolar development.

  1997cited by this paper
• Receptor Specificity of the Fibroblast Growth Factor Family*

  1996cited by this paper
• Keratinocyte growth factor is required for hair development but not for wound healing.

  1996cited by this paper
• Thy1 (+) and (-) lung fibrosis subpopulations in LEW and F344 rats.

  1994cited by this paper
• Morphologic and functional characteristics of subpopulations of murine lung fibroblasts grown in vitro

  1992cited by this paper
• Differential expression of interleukin 1 alpha by Thy-1+ and Thy-1- lung fibroblast subpopulations: enhancement of interleukin 1 alpha production by tumor necrosis factor-alpha.

  1990cited by this paper
• Differential expression of interleukin 1α by Thy‐1+ and Thy‐1− lung fibroblast subpopulations: Enhancement of interleukin 1α production by tumor necrosis factor‐α

  1990cited by this paper
• The lipid interstitial cell of the pulmonary alveolus. Age and species differences.

  1985cited by this paper
• Pulmonary di-and-triacylglycerols during the perinatal development of the rat

  1981cited by this paper
• Electron microscopic observations on the morphogenesis of the albino rat lung, with special reference to pulmonary epithelial cells.

  1970cited by this paper

• Transcriptional coordination in multicellular lineage differentiation during lung organogenesis: deciphering the role of epithelial cells as a microenvironmental regulatory hub.

  2026cites this paper
• Caffeine Protects Against Hyperoxia-Induced Structural Lung Injury and Restores Alveolar Development in Neonatal Rats

  2025cites this paper
• Matrix Softness Induces an Afibrogenic Lipofibroblast Phenotype in Fibroblasts from IPF Patients.

  2025cites this paper
• Cellular crosstalk in fibrosis: Insights into macrophage and fibroblast dynamics

  2025cites this paper
• Myofibroblasts emerge during alveolar regeneration following influenza-virus-induced lung injury.

  2025cites this paper
• Human iPSC-based model of COPD to investigate disease mechanisms, predict SARS-COV-2 outcome and test preventive immunotherapy.

  2024cites this paper
• Morphological and molecular aspects of lung development.

  2024cites this paper
• Hemodynamic Melody of Postnatal Cardiac and Pulmonary Development in Children with Congenital Heart Diseases

  2024cites this paper
• Understanding myofibroblast origin in the fibrotic lung

  2024cites this paper
• The lung mesenchyme in development, regeneration, and fibrosis

  2023cites this paper
• Stem/Progenitor Cells and Related Therapy in Bronchopulmonary Dysplasia

  2023cites this paper
• Cellular mechanisms in the pathogenesis of interstitial lung diseases.

  2023cites this paper
• Nicotinamide N-methyltransferase mediates lipofibroblast–myofibroblast transition and apoptosis resistance

  2023cites this paper
• Highlighting fibroblast plasticity in lung fibrosis: the WI-38 cell line as a model for investigating the myofibroblast and lipofibroblast switch

  2023cites this paper
• Fibroblast growth factor 10.

  2023cites this paper
• Unravelling the expanding role of FGF10 signalling in lung homeostasis and maintenance

  2023cites this paper
• Prenatal FGFR2 Signaling via PI3K/AKT Specifies the PDGFRA+ Myofibroblast.

  2023cites this paper
• Pulmonary inflammation and fibroblast immunoregulation: from bench to bedside

  2023cites this paper
• Preferential FGF18/FGFR activity in pseudoglandular versus canalicular stage human lung fibroblasts

  2023cites this paper
• Variants in FGF10 cause early onset of severe childhood interstitial lung disease: A detailed description of four affected children

  2023cites this paper
• Fgfr2b signaling is essential for the maintenance of the alveolar epithelial type 2 lineage during lung homeostasis in mice

  2022cites this paper
• FGF 10 Inhibited Spinal Microglial Activation in Neuropathic Pain via PPAR-γ/NF-κB Signaling.

  2022cites this paper
• The Role of Mesothelin in Activation of Portal Fibroblasts in Cholestatic Liver Injury

  2022cites this paper
• Phenotypic spectrum of FGF10-related disorders: a systematic review

  2022cites this paper
• The Role of Insulin Receptor Substrate Proteins in Bronchopulmonary Dysplasia and Asthma: New Potential Perspectives

  2022cites this paper
• FGF 10 Inhibited Spinal Microglial Activation in Neuropathic Pain via PPAR- c /NF- j B Signaling

  2022cites this paper
• DNMT3a promotes osteoblast differentiation and alleviates osteoporosis via the PPARγ/SCD1/GLUT1 axis.

  2022cites this paper
• Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis

  2022cites this paper
• Kub3 Deficiency Causes Aberrant Late Embryonic Lung Development in Mice by the FGF Signaling Pathway

  2022cites this paper
• FGF10 Triggers De Novo Alveologenesis in a Bronchopulmonary Dysplasia Model: Impact on Resident Mesenchymal Niche Cells

  2022cites this paper
• FGF10 triggers de novo alveologenesis in a BPD model: impact on the resident mesenchymal niche cells

  2022cites this paper
• Fibroblast growth factor receptor signalling dysregulation and targeting in breast cancer

  2022cites this paper
• New developments in the biology of fibroblast growth factors.

  2022cites this paper
• Maladaptive functional changes in alveolar fibroblasts due to perinatal hyperoxia impair epithelial differentiation

  2022cites this paper
• Generation of rat lungs by blastocyst complementation in Fgfr2b-deficient mouse model

  2022cites this paper
• Alveologenesis: What Governs Secondary Septa Formation

  2021cites this paper
• The Lung Vasculature: A Driver or Passenger in Lung Branching Morphogenesis?

  2021cites this paper
• Characterization in mice of the stromal niche maintaining AT2 stem cell self-renewal in homeostasis and disease

  2021cites this paper
• Characterization of a novel Fgf10CreERT2 knock-in mouse line targeting postnatal lung Fgf10 lineages

  2021cites this paper
• Resident interstitial lung fibroblasts and their role in alveolar stem cell niche development, homeostasis, injury, and regeneration

  2021cites this paper
• Alveolar stem cells in lung development and regrowth

  2021cites this paper
• Evidence for the involvement of lipofibroblasts, airway smooth muscle cells and FGF10 signalling in lung repair

  2021cites this paper
• Validation of a Novel Fgf10Cre–ERT2 Knock-in Mouse Line Targeting FGF10Pos Cells Postnatally

  2021cites this paper
• FGF10 and Lipofibroblasts in Lung Homeostasis and Disease: Insights Gained From the Adipocytes

  2021influential citation
• Characterization in mice of the resident mesenchymal niche maintaining AT2 stem cell proliferation in homeostasis and disease

  2021cites this paper
• Cross-Talk Between Inflammation and Fibroblast Growth Factor 10 During Organogenesis and Pathogenesis: Lessons Learnt From the Lung and Other Organs

  2021cites this paper
• Categorization of lung mesenchymal cells in development and fibrosis

  2021cites this paper
• Dissecting the Role of Mesenchymal Stem Cells in Idiopathic Pulmonary Fibrosis: Cause or Solution

  2021cites this paper
• Potential Impact of Diabetes and Obesity on Alveolar Type 2 (AT2)-Lipofibroblast (LIF) Interactions After COVID-19 Infection

  2021influential citation
• Fibroblasts: Origins, definitions, and functions in health and disease.

  2021cites this paper
• Fibrotic Idiopathic Interstitial Lung Disease: The Molecular and Cellular Key Players

  2021influential citation
• Fgf10/Fgfr2b Signaling in Mammary Gland Development, Homeostasis, and Cancer

  2020cites this paper
• Targeting p16INK4a Promotes Lipofibroblasts and Alveolar Regeneration After Early Life Injury.

  2020cites this paper
• RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1

  2020cites this paper
• Definition and Signatures of Lung Fibroblast Populations in Development and Fibrosis in Mice and Men

  2020cites this paper
• Editorial: The Fibroblast Growth Factor Signaling Pathway in Metabolic Regulation, Development, Disease, and Repair After Injury

  2020cites this paper
• Use of the Reversible Myogenic to Lipogenic Transdifferentiation Switch for the Design of Pre-clinical Drug Screening in Idiopathic Pulmonary Fibrosis

  2020cites this paper
• Multilineage murine stem cells generate complex organoids to model distal lung development and disease

  2020cites this paper
• Fgf10 Signaling-Based Evidence for the Existence of an Embryonic Stage Distinct From the Pseudoglandular Stage During Mouse Lung Development

  2020cites this paper
• The Elephant in the Lung: Integrating lineage-tracing, molecular markers, and single cell sequencing data to identify distinct fibroblast populations during lung development and regeneration.

  2020cites this paper
• Generation of Lungs by Blastocyst Complementation in Apneumic Fgf10-Deficient Mice.

  2020cites this paper
• Understanding Human Lung Development through In Vitro Model Systems

  2020cites this paper
• Failure to Down-Regulate miR-154 Expression in Early Postnatal Mouse Lung Epithelium Suppresses Alveologenesis, with Changes in Tgf-β Signaling Similar to those Induced by Exposure to Hyperoxia

  2020cites this paper
• Temporospatial Expression of Fgfr1 and 2 During Lung Development, Homeostasis, and Regeneration

  2020cites this paper
• Good Things Come in 2s: Type 2 Alveolar Epithelial Cells and Fibroblast Growth Factor Receptor 2

  2020cites this paper
• Study on the changes of ADRP+ cell population in the process of pulmonary fibrosis

  2020cites this paper
• FGF Signaling in Lung Development and Disease: Human Versus Mouse

  2019cites this paper
• The Tcf21 lineage constitutes the lung lipofibroblast population.

  2019cites this paper
• A Comprehensive Analysis of Fibroblast Growth Factor Receptor 2b Signaling on Epithelial Tip Progenitor Cells During Early Mouse Lung Branching Morphogenesis

  2019cites this paper
• Transcriptome Analysis of Landrace Pig Subcutaneous Preadipocytes during Adipogenic Differentiation

  2019cites this paper
• Evidence for lung repair and regeneration in humans: key stem cells and therapeutic functions of fibroblast growth factors

  2019cites this paper
• Elastin in lung development and disease pathogenesis.

  2018cites this paper
• Discordant roles for FGF ligands in lung branching morphogenesis between human and mouse

  2018cites this paper
• Fgf10 Signaling in Lung Development, Homeostasis, Disease, and Repair After Injury

  2018influential citation
• Impact of Fgf10 deficiency on pulmonary vasculature formation in a mouse model of bronchopulmonary dysplasia

  2018cites this paper
• Recent advances in the pathogenesis of BPD.

  2018cites this paper
• Spatial and temporal inhibition of FGFR2b ligands reveals continuous requirements and novel targets in mouse inner ear morphogenesis

  2018cites this paper
• Novel functional role of GH/IGF-I in neonatal lung myofibroblasts and in rat lung growth after intrauterine growth restriction.

  2018cites this paper
• Role of Fibroblast Growth Factor 10 in Mesenchymal Cell Differentiation During Lung Development and Disease

  2018influential citation
• Impaired Angiogenic Supportive Capacity and Altered Gene Expression Profile of Resident CD146+ Mesenchymal Stromal Cells Isolated from Hyperoxia-Injured Neonatal Rat Lungs

  2018cites this paper
• Developmental mechanisms and adult stem cells for therapeutic lung regeneration.

  2018cites this paper
• Epithelial Regeneration and Lung Stem Cells

  2017cites this paper
• Fgf10 deficiency is causative for lethality in a mouse model of bronchopulmonary dysplasia

  2017cites this paper
• The innate immune response in fetal lung mesenchymal cells targets VEGFR2 expression and activity.

  2017cites this paper
• Understanding the developmental pathways pulmonary fibroblasts may follow during alveolar regeneration

  2017cites this paper
• Human embryonic lung epithelial tips are multipotent progenitors that can be expanded in vitro as long-term self-renewing organoids

  2017cites this paper
• Heterogeneity of Fibroblasts and Myofibroblasts in Pulmonary Fibrosis

  2017cites this paper
• HOXA5 plays tissue-specific roles in the developing respiratory system

  2017cites this paper
• Recent advances in our understanding of the mechanisms of late lung development and bronchopulmonary dysplasia.

  2017cites this paper
• FGF receptors control alveolar elastogenesis

  2017cites this paper
• Lipid‐body containing interstitial cells (lipofibroblasts) in the lungs of various mouse strains

  2017cites this paper
• Therapeutic and pathological roles of fibroblast growth factors in pulmonary diseases

  2017cites this paper
• A novel mouse Cre‐driver line targeting Perilipin 2‐expressing cells in the neonatal lung

  2017cites this paper
• Genetic insights into the mechanisms of Fgf signaling

  2016cites this paper
• Mesodermal lineages in the developing respiratory system.

  2016cites this paper
• Alveologenesis: key cellular players and fibroblast growth factor 10 signaling

  2016cites this paper