Genetic insights into the mechanisms of Fgf signaling

J. R. Brewer,P. Mazot,Philippe Soriano

Published 2016 in Genes & Development

ABSTRACT

The fibroblast growth factor (Fgf) family of ligands and receptor tyrosine kinases is required throughout embryonic and postnatal development and also regulates multiple homeostatic functions in the adult. Here, Brewer et al. review the mechanisms of Fgf signaling by focusing on genetic strategies that enable in vivo analysis.

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