Interaction between von Willebrand factor and glycoprotein Ib activates Src kinase in human platelets: role of phosphoinositide 3-kinase.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Blood

• Publication date

  2003-02-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.2491/JJSTH.14.18PMID 12393736
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• von Willebrand Factor

  2002cited by this paper
• Phosphatidylinositol 3-Kinase p85 Adaptor Function in T-cells

  2002cited by this paper
• Role of Fc receptor gamma-chain in platelet glycoprotein Ib-mediated signaling.

  2001cited by this paper
• Platelet Activation by von Willebrand Factor Requires Coordinated Signaling through Thromboxane A2 and FcγIIA Receptor*

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• The Vascular Biology of the Glycoprotein Ib-IX-V Complex

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  2001cited by this paper
• Evidence for a functional association between phosphatidylinositol 3-kinase and c-src in the spreading response of osteoclasts to colony-stimulating factor-1.

  2000cited by this paper
• Phosphoinositide 3-kinase forms a complex with platelet membrane glycoprotein Ib-IX-V complex and 14-3-3zeta.

  2000cited by this paper
• Phosphoinositide 3-kinase forms a complex with platelet membrane glycoprotein Ib-IX-V complex and 14-3-3ζ

  2000cited by this paper
• The SH3 Domain Directs Acto-Myosin-Dependent Targeting of v-Src to Focal Adhesions via Phosphatidylinositol 3-Kinase

  2000cited by this paper
• Platelet release of trimolecular complex components MT1-MMP/TIMP2/MMP2: involvement in MMP2 activation and platelet aggregation.

  2000cited by this paper
• Activation of protein-tyrosine kinase pathways in human platelets stimulated with the A1 domain of von Willebrand factor.

  2000cited by this paper
• Signaling across the Platelet Adhesion Receptor Glycoprotein Ib-IX Induces αIIbβ3 Activation Both in Platelets and a Transfected Chinese Hamster Ovary Cell System*

  2000cited by this paper
• Synergistic adhesive interactions and signaling mechanisms operating between platelet glycoprotein Ib/IX and integrin alpha IIbbeta 3. Studies in human platelets ans transfected Chinese hamster ovary cells.

  2000cited by this paper
• Role of caspase in a subset of human platelet activation responses.

  1999cited by this paper
• Differential Regulation of Platelet Aggregation by Matrix Metalloproteinases-9 and -2

  1999cited by this paper
• Phosphatidylinositol 3′‐kinase and tyrosine‐phosphatase activation positively modulate Convulxin‐induced platelet activation. Comparison with collagen

  1999cited by this paper
• Analysis of the Roles of 14-3-3 in the Platelet Glycoprotein Ib-IX–Mediated Activation of Integrin αIIbβ3 Using a Reconstituted Mammalian Cell Expression Model

  1999cited by this paper
• HEMOSTASIS , THROMBOSIS , AND VASCULAR BIOLOGY Role of Caspase in a Subset of Human Platelet Activation Responses

  1999cited by this paper
• The von Willebrand Factor-Glycoprotein Ib/V/IX Interaction Induces Actin Polymerization and Cytoskeletal Reorganization in Rolling Platelets and Glycoprotein Ib/V/IX-transfected Cells*

  1999cited by this paper
• Glycoprotein Ib-V-IX, a receptor for von Willebrand factor, couples physically and functionally to the Fc receptor gamma-chain, Fyn, and Lyn to activate human platelets.

  1999cited by this paper
• Phosphoinositide kinases.

  1998cited by this paper
• Structure and function of phosphoinositide 3-kinases.

  1998cited by this paper
• Activation of phospholipase Cγ by PI 3‐kinase‐induced PH domain‐mediated membrane targeting

  1998cited by this paper
• The p85 and p110 subunits of phosphatidylinositol 3-kinase-alpha are substrates, in vitro, for a constitutively associated protein tyrosine kinase in platelets.

  1998cited by this paper
• Localization and Translocation of MMP-2 during Aggregation of Human Platelets

  1998cited by this paper
• Activation of phospholipase C gamma by PI 3-kinase-induced PH domain-mediated membrane targeting.

  1998cited by this paper
• Phosphatidylinositol 3-kinase-gamma activates Bruton's tyrosine kinase in concert with Src family kinases.

  1997cited by this paper
• Calpain Regulation of Cytoskeletal Signaling Complexes in Von Willebrand Factor-stimulated Platelets

  1997cited by this paper
• Release of gelatinase A during platelet activation mediates aggregation

  1997cited by this paper
• Tyrosine phosphorylation and p72syk activation by an anti-glycoprotein Ib monoclonal antibody.

  1997cited by this paper
• Involvement of Phosphatidylinositol 3-Kinase in NFAT Activation in T Cells*

  1997cited by this paper
• Glycoprotein Ib-von Willebrand factor interactions activate tyrosine kinases in human platelets.

  1997cited by this paper
• Platelet GPIb-V-IX Complex

  1997cited by this paper
• Phosphatidylinositol 3-kinase-γ activates Bruton’s tyrosine kinase in concert with Src family kinases

  1997cited by this paper
• Glycoprotein Ib-von Willebrand factor interactions activate tyrosine kinases in human platelets

  1997cited by this paper
• von Willebrand factor.

  1997cited by this paper
• Identification of amino acid residues required for a specific interaction between Src‐tyrosine kinase and proline‐rich region of phosphatidylinositol‐3′ kinase

  1996cited by this paper
• Phosphoinositide 3-kinase activation and platelet function.

  1996cited by this paper
• Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase.

  1996cited by this paper
• The Cytoplasmic Domain of the -Subunit of Glycoprotein (GP) Ib Mediates Attachment of the Entire GP Ib-IX Complex to the Cytoskeleton and Regulates von Willebrand Factor-induced Changes in Cell Morphology (*)

  1996cited by this paper
• Inhibition assay for the binding of biotinylated von Willebrand factor to platelet-bound microtiter wells in the presence of ristocetin or botrocetin.

  1996cited by this paper
• Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

  1996cited by this paper
• Isolation and Characterization of jararaca GPIb-BP, a Snake Venom Antagonist Specific to Platelet Glycoprotein lb

  1995cited by this paper
• Protein tyrosine phosphorylation in human platelets induced by interaction between glycoprotein Ib and von Willebrand factor.

  1995cited by this paper
• Structural elements influencing von Willebrand factor (vWF) binding affinity for platelet glycoprotein Ib within a dispase-digested vWF fragment.

  1994cited by this paper
• Shedding of adhesion receptors from the surface of activated platelets.

  1994cited by this paper
• Shear-stress-induced von Willebrand factor binding to platelets causes the activation of tyrosine kinase(s).

  1994cited by this paper
• Adhesion receptor activation of phosphatidylinositol 3-kinase. von Willebrand factor stimulates the cytoskeletal association and activation of phosphatidylinositol 3-kinase and pp60c-src in human platelets.

  1994cited by this paper
• The interaction of the von Willebrand factor-A1 domain with platelet glycoprotein Ib/IX. The role of glycosylation and disulfide bonding in a monomeric recombinant A1 domain protein.

  1993cited by this paper
• Redistribution of activated pp60c-src to integrin-dependent cytoskeletal complexes in thrombin-stimulated platelets

  1993cited by this paper
• Src-homology 3 domain of protein kinase p59fyn mediates binding to phosphatidylinositol 3-kinase in T cells.

  1993cited by this paper
• Translocation of pp60c‐src to the cytoskeleton during platelet aggregation.

  1992cited by this paper
• Association of pp60src with Triton X-100-insoluble residue in human blood platelets requires platelet aggregation and actin polymerization.

  1992cited by this paper
• von Willebrand factor binding to platelet GpIb initiates signals for platelet activation.

  1991cited by this paper
• Purification of botrocetin from Bothrops jararaca venom. Analysis of the botrocetin-mediated interaction between von Willebrand factor and the human platelet membrane glycoprotein Ib-IX complex.

  1989cited by this paper

• Increased RhoA pathway activation downstream of αIIbβ3/SRC contributes to heterozygous Bernard Soulier syndrome

  2025cites this paper
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  2024cites this paper
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  2022cites this paper
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  2018cites this paper
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  2018cites this paper
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  2018cites this paper
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  2017cites this paper
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  2017cites this paper
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  2015cites this paper
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  2015cites this paper
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  2014cites this paper
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  2014cites this paper
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  2014cites this paper
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• The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activation.

  2008cites this paper
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• Identification of FcgammaRIIa as the ITAM-bearing receptor mediating alphaIIbbeta3 outside-in integrin signaling in human platelets.

  2008cites this paper
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  2008cites this paper
• A functional 14-3-3 (cid:1) –independent association of PI3-kinase with glycoprotein Ib (cid:2) , the major ligand-binding subunit of the platelet glycoprotein Ib-IX-V complex

  2008cites this paper
• A functional 14-3-3zeta-independent association of PI3-kinase with glycoprotein Ib alpha, the major ligand-binding subunit of the platelet glycoprotein Ib-IX-V complex.

  2008cites this paper
• Src family tyrosine kinase Lyn mediates VWF/GPIb-IX-induced platelet activation via the cGMP signaling pathway.

  2008cites this paper
• Identification of Fc (cid:1) RIIa as the ITAM-bearing receptor mediating (cid:2) IIb (cid:3) 3 outside-in integrin signaling in human platelets

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• c-Myc-mediated genomic instability proceeds via a megakaryocytic endomitosis pathway involving Gp1bα

  2007cites this paper
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  2004cites this paper
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  2004cites this paper
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  2003cites this paper
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  2003cites this paper
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