T Cell Cycle and Immunosenescence: Role of Aging in the T Cell Proliferative Behavior and Status Quo Maintenance

No abstract is available for this paper.

• Publication year

  2019

• Venue

  Handbook of Immunosenescence

• Publication date

  Unknown publication date

• Fields of study

  Not labeled

• Identifiers
  DOI 10.1007/978-3-319-99375-1_13
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Niches for the Long-Term Maintenance of Tissue-Resident Memory T Cells

  2018cited by this paper
• The Changing Landscape of Naive T Cell Receptor Repertoire With Human Aging

  2018cited by this paper
• Immunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes?

  2018cited by this paper
• Synaptic Interactions in Germinal Centers

  2018cited by this paper
• Successful and Maladaptive T Cell Aging.

  2017cited by this paper
• The twilight of immunity: emerging concepts in aging of the immune system

  2017cited by this paper
• DNA damage, metabolism and aging in pro‐inflammatory T cells: Rheumatoid arthritis as a model system

  2017cited by this paper
• Activation-Induced Autophagy Is Preserved in CD4+ T-Cells in Familial Longevity

  2017cited by this paper
• From inflamm-aging to immune-paralysis: a slippery slope during aging for immune-adaptation

  2016cited by this paper
• Roles of calpain-calpastatin system (CCS) in human T cell activation

  2016cited by this paper
• Senescence of T Lymphocytes: Implications for Enhancing Human Immunity.

  2016cited by this paper
• Aging of the Immune System. Mechanisms and Therapeutic Targets.

  2016cited by this paper
• Recapitulating adult human immune traits in laboratory mice by normalizing environment

  2016cited by this paper
• Two Niches in the Bone Marrow: A Hypothesis on Life-long T Cell Memory.

  2016cited by this paper
• Protective Effect of Amyloid-β Peptides Against Herpes Simplex Virus-1 Infection in a Neuronal Cell Culture Model

  2016cited by this paper
• Dynamics of Individual T Cell Repertoires: From Cord Blood to Centenarians

  2016cited by this paper
• Naive T Cell Maintenance and Function in Human Aging

  2015cited by this paper
• Increased μ-Calpain Activity in Blasts of Common B-Precursor Childhood Acute Lymphoblastic Leukemia Correlates with Their Lower Susceptibility to Apoptosis

  2015cited by this paper
• Activation-induced and damage-induced cell death in aging human T cells.

  2015cited by this paper
• On the immunological theory of aging.

  2014cited by this paper
• T-cell aging in rheumatoid arthritis

  2014cited by this paper
• T cell receptor-mediated activation is a potent inducer of macroautophagy in human CD8(+)CD28(+) T cells but not in CD8(+)CD28(-) T cells.

  2014cited by this paper
• p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8⁺ T cells.

  2014cited by this paper
• AMPK-TAB1 activated p38 drives human T cell senescence

  2014cited by this paper
• Cellular signaling in the aging immune system.

  2014cited by this paper
• Aging of the T Cell Compartment in Mice and Humans: From No Naive Expectations to Foggy Memories

  2014cited by this paper
• Expression of calpain-calpastatin system (CCS) member proteins in human lymphocytes of young and elderly individuals; pilot baseline data for the CALPACENT project

  2013cited by this paper
• The Janus Head of T Cell Aging – Autoimmunity and Immunodeficiency

  2013cited by this paper
• Stemness of T cells and the hematopoietic stem cells: fate, memory, niche, cytokines.

  2013cited by this paper
• Immunosenescence and cancer.

  2013cited by this paper
• A novel method for autophagy detection in primary cells

  2012cited by this paper
• Changes in primary lymphoid organs with aging.

  2012cited by this paper
• Conventional calpains and programmed cell death.

  2011cited by this paper
• Interaction of regulatory T cells with antigen-presenting cells in health and disease.

  2008cited by this paper
• Delayed ageing through damage protection by the Arf/p53 pathway

  2007cited by this paper
• Lower expression of catalytic and structural subunits of the proteasome contributes to decreased proteolysis in peripheral blood T lymphocytes during aging.

  2007cited by this paper
• Augmented Wnt Signaling in a Mammalian Model of Accelerated Aging

  2007cited by this paper
• α-Klotho as a Regulator of Calcium Homeostasis

  2007cited by this paper
• Klotho: an antiaging protein involved in mineral and vitamin D metabolism.

  2007cited by this paper
• Healthy Aging Is Associated with Unaltered Production of Immunoreactive Growth Hormone but Impaired Neuroimmunomodulation

  2007cited by this paper
• Untangling klotho's role in calcium homeostasis.

  2007cited by this paper
• Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans.

  2007cited by this paper
• Impact of niche aging on thymic regeneration and immune reconstitution.

  2007cited by this paper
• Increased Wnt Signaling During Aging Alters Muscle Stem Cell Fate and Increases Fibrosis

  2007cited by this paper
• Klotho-related Protein Is a Novel Cytosolic Neutral β-Glycosylceramidase*

  2007cited by this paper
• TNF family ligands define niches for T cell memory.

  2007cited by this paper
• Mitotic cell death by chromosome fragmentation.

  2007cited by this paper
• Thymic output and functionality of the IL‐7/IL‐7 receptor system in centenarians: implications for the neolymphogenesis at the limit of human life

  2006cited by this paper
• Age-dependent modifications of Type 1 and Type 2 cytokines within virgin and memory CD4+ T cells in humans.

  2006cited by this paper
• Cytokine receptor signalling and aging.

  2006cited by this paper
• Telomeres, immune aging and autoimmunity.

  2006cited by this paper
• Decreased expression of DNA repair proteins Ku70 and Mre11 is associated with aging and may contribute to the cellular senescence

  2006cited by this paper
• Differential expression of WNTs and FRPs in the synovium of rheumatoid arthritis and osteoarthritis.

  2006cited by this paper
• Immunity and ageing in man.

  2006cited by this paper
• Stemming the tide of thymic aging

  2006cited by this paper
• Inflamm-aging, cytokines and aging: state of the art, new hypotheses on the role of mitochondria and new perspectives from systems biology.

  2006cited by this paper
• Naïve T Cells in the Elderly

  2006cited by this paper
• Ergebnisse aus der biomedizinischen Alternsforschung

  2006cited by this paper
• Dysregulation of T-Cell Function in the Elderly

  2005cited by this paper
• The Influence of Age on T Cell Generation and TCR Diversity1

  2005cited by this paper
• Inflamm‐ageing and lifelong antigenic load as major determinants of ageing rate and longevity

  2005cited by this paper
• Expression profiles and functional analyses of Wnt-related genes in human joint disorders.

  2005cited by this paper
• An investigation of DNA mismatch repair capacity under normal culture conditions and under conditions of supra-physiological challenge in human CD4+T cell clones from donors of different ages.

  2005cited by this paper
• Wnt signalling in rheumatoid arthritis.

  2005cited by this paper
• T cell development and receptor diversity during aging.

  2005cited by this paper
• Modulation of CD28 expression with anti–tumor necrosis factor α therapy in rheumatoid arthritis

  2005cited by this paper
• Autolysosomes accumulate during in vitro CD8+ T-lymphocyte aging and may participate in induced death sensitization of senescent cells.

  2004cited by this paper
• Longevity in vitro of human CD4+ T helper cell clonesderived from young donors and elderly donors, or fromprogenitor cells: age-associated differences in cellsurface molecule expression and cytokine secretion

  2004cited by this paper
• Lymphotoxin beta-mediated stimulation of synoviocytes in rheumatoid arthritis.

  2004cited by this paper
• Comparative histology of lymph nodes from aged animals and humans with special reference to the proportional areas of the nodal cortex and sinus.

  2004cited by this paper
• CD28nullCD4+ T Cells – Characterization of an Effector Memory T‐Cell Population in Patients with Rheumatoid Arthritis

  2004cited by this paper
• Decreased proliferative capability of CD4(+) cells of elderly people is associated with faster loss of activation-related antigens and accumulation of regulatory T cells.

  2004cited by this paper
• Proliferation and apoptosis of human CD8(+)CD28(+) and CD8(+)CD28(-) lymphocytes during aging.

  2004cited by this paper
• Wnt signaling in B and T lymphocytes.

  2004cited by this paper
• Paradoxical age-related cell cycle quickening of human CD4(+) lymphocytes: a role for cyclin D1 and calpain.

  2004cited by this paper
• Age-dependent response of lymphocytes in the induction of the linker histone variant, H1 degrees and histone H4 acetylation after treatment with the histone deacetylase inhibitor, trichostatin A.

  2004cited by this paper
• Ageing, autoimmunity and arthritis: Perturbations of TCR signal transduction pathways with ageing – a biochemical paradigm for the ageing immune system

  2003cited by this paper
• Continuous remodeling as a key to aging and survival: an interview with Claudio Franceschi. Interview by Suresh I S Rattan.

  2003cited by this paper
• Proliferation of CD8+ in culture of human T cells derived from peripheral blood of adult donors and cord blood of newborns.

  2003cited by this paper
• DNA damage recognition and repair capacities in human naïve and memory T cells from peripheral blood of young and elderly subjects.

  2003cited by this paper
• Clonally expanded CD4+CD28null T cells in rheumatoid arthritis use distinct combinations of T cell receptor BV and BJ elements

  2003cited by this paper
• Centenarians as a model for healthy aging.

  2003cited by this paper
• Modulation of human lymphocyte proliferative response with aging.

  2002cited by this paper
• T-Cell–Mediated Lysis of Endothelial Cells in Acute Coronary Syndromes

  2002cited by this paper
• Human CD4+ T cell clone longevity in tissue culture: lack of influence of donor age or cell origin.

  2002cited by this paper
• Clonal Selection, Clonal Senescence, and Clonal Succession: The Evolution of the T Cell Response to Infection with a Persistent Virus1

  2002cited by this paper
• Age associated decline in CD25 and CD28 expression correlate with an increased susceptibility to CD95 mediated apoptosis in T cells.

  2002cited by this paper
• Lack of Antibody Production Following Immunization in Old Age: Association with CD8+CD28− T Cell Clonal Expansions and an Imbalance in the Production of Th1 and Th2 Cytokines1

  2002cited by this paper
• Lymphocyte kinetics: the interpretation of labelling data.

  2002cited by this paper
• Ubiquitin-proteasome pathway is compromised in CD45RO+ and CD45RA+ T lymphocyte subsets during aging.

  2002cited by this paper
• Modulation of the activity of calcium-activated neutral proteases (calpains) in chronic lymphocytic leukemia (B-CLL) cells.

  2002cited by this paper
• Flow cytometric analysis of cell division history using dilution of carboxyfluorescein diacetate succinimidyl ester, a stably integrated fluorescent probe.

  2001cited by this paper
• Age-related increase of frequency of a new, phenotypically distinct subpopulation of human peripheral blood T cells expressing lowered levels of CD4.

  2001cited by this paper
• Age-related accumulation of oxidative DNA damage and alterations in levels of p16(INK4a/CDKN2a), p21(WAF1/CIP1/SDI1) and p27(KIP1) in human CD4+ T cell clones in vitro.

  2001cited by this paper
• Wnt signaling is required for thymocyte development and activates Tcf‐1 mediated transcription

  2001cited by this paper
• Activation‐induced T cell death occurs at G1A phase of the cell cycle

  2000cited by this paper
• The network and the remodeling theories of aging: historical background and new perspectives.

  2000cited by this paper
• Costimulatory mechanisms in the elderly.

  2000cited by this paper
• Distribution of age‐related thymulin titres in normal subjects through the course of life

  2000cited by this paper
• Killer Cell Activating Receptors Function as Costimulatory Molecules on CD4+CD28null T Cells Clonally Expanded in Rheumatoid Arthritis1

  2000cited by this paper

• No citing papers are available for this paper.