The effects of methylmercury on mitochondrial function and reactive oxygen species formation in rat striatal synaptosomes are age-dependent.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Toxicological Sciences

• Publication date

  2005-09-01

• Fields of study

  Biology, Medicine, Environmental Science

• Identifiers
  DOI 10.1093/TOXSCI/KFI224PMID 15958658
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Hippocampal antioxidant system in neonates from methylmercury-intoxicated rats.

  2004cited by this paper
• Developmental neuropathology of environmental agents.

  2004cited by this paper
• The role of metallothionein II in neuronal differentiation and survival.

  2003cited by this paper
• Discussion of the Role of the Extracellular Signal-Regulated Kinase-Phospholipase A2 Pathway in Production of Reactive Oxygen Species in Alzheimer's Disease

  2003cited by this paper
• Evaluation of the probes 2',7'-dichlorofluorescin diacetate, luminol, and lucigenin as indicators of reactive species formation.

  2003cited by this paper
• Prenatal methylmercury exposure from ocean fish consumption in the Seychelles child development study.

  2003cited by this paper
• Methylmercury-induced reactive oxygen species formation in neonatal cerebral astrocytic cultures is attenuated by antioxidants.

  2003cited by this paper
• Mechanism of action of methylmercury on in vivo striatal dopamine release. Possible involvement of dopamine transporter.

  2002cited by this paper
• Acute exposure to methylmercury opens the mitochondrial permeability transition pore in rat cerebellar granule cells.

  2002influential reference
• Free Radicals and Brain Damage in the Newborn

  2001cited by this paper
• [Mitochondrial control of apoptosis].

  2001cited by this paper
• Early acute necrosis, delayed apoptosis and cytoskeletal breakdown in cultured cerebellar granule neurons exposed to methylmercury

  2000influential reference
• Glutathione metabolism in brain

  2000cited by this paper
• Age-related changes in reactive oxygen species production in rat brain homogenates.

  2000influential reference
• Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species.

  2000cited by this paper
• The involvement of microtubular disruption in methylmercury-induced apoptosis in neuronal and nonneuronal cell lines.

  1999influential reference
• Effects of prenatal and postnatal methylmercury exposure from fish consumption on neurodevelopment: outcomes at 66 months of age in the Seychelles Child Development Study.

  1998cited by this paper
• Methylmercury antagonizes the survival-promoting activity of insulin-like growth factor on developing cerebellar granule neurons.

  1998influential reference
• The effect of methylmercury on skeletal muscle in the rat: a histopathological study.

  1998cited by this paper
• Pathways mediating Ca2+ entry in rat cerebellar granule cells following in vitro exposure to methyl mercury.

  1997cited by this paper
• Mitochondrial control of apoptosis.

  1997cited by this paper
• Cognitive deficit in 7-year-old children with prenatal exposure to methylmercury.

  1997cited by this paper
• Oxidative stress in neurotoxic effects of methylmercury poisoning.

  1996cited by this paper
• Methylmercury induces apoptosis of rat cerebellar neurons in primary culture.

  1994influential reference
• Methylmercury poisoning induces oxidative stress in the mouse brain.

  1994cited by this paper
• Reactive oxygen species formation as a biomarker of methylmercury and trimethyltin neurotoxicity.

  1992influential reference
• Comparative action of methylmercury and divalent inorganic mercury on nerve terminal and intraterminal mitochondrial membrane potentials.

  1992cited by this paper
• Disruption of the potential across the synaptosomal plasma membrane and mitochondria by neurotoxic agents.

  1991cited by this paper
• J-aggregate formation of a carbocyanine as a quantitative fluorescent indicator of membrane potential.

  1991cited by this paper
• Oxidative mechanisms underlying methyl mercury neurotoxicity

  1991cited by this paper
• Prevention of chemically induced synaptosomal changes

  1990cited by this paper
• Organometal-induced increases in oxygen reactive species: the potential of 2',7'-dichlorofluorescin diacetate as an index of neurotoxic damage.

  1990cited by this paper
• Physical and mental development of children with prenatal exposure to mercury from fish. Stage 2. Interviews and psychological tests at age 6.

  1990cited by this paper
• The effects of methylmercury on the developing brain.

  1989cited by this paper
• Increased free intrasynaptosomal Ca2+ by neurotoxic organometals: distinctive mechanisms.

  1987cited by this paper
• Physical and mental development of children with prenatal exposure to mercury from fish

  1986cited by this paper
• Physical and mental development of children with prenatal exposure to mercury from fish. Stage 1: Preliminary tests at age 4

  1986cited by this paper
• Free radicals in biology and medicine

  1985influential reference
• Paradoxical effects of methylmercury on the kinetics of cytochrome c oxidase.

  1984cited by this paper
• Superoxide dismutase, glutathione peroxidase and catalase in developing rat brain.

  1982cited by this paper
• Changes in rat liver mitochondria and endoplasmic reticulum during development and differentiation.

  1973cited by this paper
• Changes in rat liver mitochondria and endoplasmic reticulum during development and differentiation.

  1973cited by this paper
• A PHYSICOCHEMICAL RATIONALE FOR THE BIOLOGICAL ACTIVITY OF MERCURY AND ITS COMPOUNDS

  1957cited by this paper
• FOCAL CEREBRAL AND CEREBELLAR ATROPHY IN A HUMAN SUBJECT DUE TO ORGANIC MERCURY COMPOUNDS

  1954cited by this paper
• Enzyme Changes During Growth and Differentiation in the Tissues of the Newborn Rat

  1945influential reference
• Partial Inactivation of Cytochrome c Oxidase by Nonpolar Mercurial Reagents *

  year unknowncited by this paper

• Mercury-induced excitotoxicity in autism spectrum disorder: disruption of glutamatergic homeostasis and the therapeutic role of the selenium-glutathione axis.

  2026cites this paper
• Prospective Study of Mercury Exposure from Pregnancy and Its Relation with Telomere Length in Spanish Children

  2024cites this paper
• Early life exposure to mercury and relationships with telomere length and mitochondrial DNA content in European children.

  2024cites this paper
• Genetic factors in methylmercury-induced neurotoxicity: What have we learned from Caenorhabditis elegans models?

  2023cites this paper
• Methylmercury Decreases AMPA Receptor Subunit GluA2 Levels in Cultured Rat Cortical Neurons.

  2023cites this paper
• Variation in pentose phosphate pathway-associated metabolism dictates cytotoxicity outcomes determined by tetrazolium reduction assays

  2023cites this paper
• Methylmercury, oxidative stress, and neurodegeneration

  2021cites this paper
• MicroRNA Expression Influences Methylmercury-Induced Lipid Accumulation and Mitochondrial Toxicity in Caenorhabditis elegans.

  2021cites this paper
• DNA methylation changes associated with prenatal mercury exposure: A meta-analysis of prospective cohort studies from PACE consortium

  2021cites this paper
• Methylmercury induces neuronal cell death by inducing TNF-α expression through the ASK1/p38 signaling pathway in microglia

  2021cites this paper
• RETRACTED ARTICLE: Thymoquinone alleviates mitochondrial viability and apoptosis in diclofenac-induced acute kidney injury (AKI) via regulating Mfn2 and miR-34a mRNA expressions

  2020cites this paper
• Chronic methylmercury exposure causes spinal cord impairment: proteomic modulation and oxidative stress.

  2020cites this paper
• Neuroprotective effects of mitoquinone and oleandrin on Parkinson’s disease model in zebrafish

  2019cites this paper
• Toxicity of mercury: Molecular evidence.

  2019cites this paper
• Human-induced pluripotent stems cells as a model to dissect the selective neurotoxicity of methylmercury.

  2019cites this paper
• Depolysulfidation of Drp1 induced by low-dose methylmercury exposure increases cardiac vulnerability to hemodynamic overload

  2019cites this paper
• Methylmercury Induces Metabolic Alterations in Caenorhabditis elegans: Role for C/EBP Transcription Factor.

  2019influential citation
• Mitochondrial respiratory chain inhibition and Na+K+ATPase dysfunction are determinant factors modulating the toxicity of nickel in the brain of indian catfish Clarias batrachus L.

  2018cites this paper
• Brain morphometric profiles and their seasonal modulation in fish (Liza aurata) inhabiting a mercury contaminated estuary.

  2018cites this paper
• Review and Prospective : Hydrogen Sul fi de Rescues Mercury-Induced Toxicity -

  2017cites this paper
• Methylmercury and Paraquat Induced Toxicity in the Mitochondria of Dopamine Neurons

  2017cites this paper
• Exposure to Electrophiles Impairs Reactive Persulfide-Dependent Redox Signaling in Neuronal Cells.

  2017cites this paper
• Effects of methyl and inorganic mercury exposure on genome homeostasis and mitochondrial function in Caenorhabditis elegans.

  2017cites this paper
• Hyperoxia and the Immature Brain

  2017cites this paper
• A brain proteome profile in rats exposed to methylmercury or thimerosal (ethylmercury)

  2016cites this paper
• Low-Dose Methylmercury-Induced Apoptosis and Mitochondrial DNA Mutation in Human Embryonic Neural Progenitor Cells

  2016cites this paper
• Delayed effects of methylmercury on the mitochondria of dopaminergic neurons and developmental toxicity in zebrafish larvae (Danio rerio).

  2016cites this paper
• The effects of methyl mercury on mitochondrial voltage in embryonic glial cells

  2015cites this paper
• Impact of methylmercury exposure on mitochondrial energetics in AC16 and H9C2 cardiomyocytes.

  2015cites this paper
• Phyllantus niruri Protects against Fe2+ and SNP Induced Oxidative Damage in Mitochondrial Enriched Fractions of Rats Brain

  2015cites this paper
• Environmental pollutants and lifestyle factors induce oxidative stress and poor prenatal development.

  2014cites this paper
• Alterations in the Atlantic COD (Gadus morhua) Hepatic Thiol-Proteome After Methylmercury Exposure

  2014cites this paper
• Environmental Factors, Oxidative Stress, and Adverse Developmental Outcomes 27

  2014cites this paper
• Oxygen Vulnerability in the Immature Brain

  2014cites this paper
• Active mitochondria in growth cones of neurons treated with methyl mercury.

  2014cites this paper
• Perinatal and Prenatal Disorders

  2014cites this paper
• The Cytotoxic Effects of Methylmercury on Cardiomyocytes: A Possible Implication for Heart Diseases?

  2014cites this paper
• Protective effect of curcumin against heavy metals-induced liver damage.

  2014cites this paper
• Maternal Nutrition, Oxidative Stress and Prenatal Devlopmental Outcomes

  2013cites this paper
• Exposição aguda ao Metilmercúrio em ratos em desenvolvimento: mini-revisão

  2013cites this paper
• Protective Effects of Memantine Against Methylmercury-Induced Glutamate Dyshomeostasis and Oxidative Stress in Rat Cerebral Cortex

  2013cites this paper
• Antimalarial activity and pharmacokinetic properties of new chemical entities

  2013cites this paper
• The Developmental and Physiological Interactions between Free Radicals and Antioxidant Defense System: Effect of Environmental Pollutants

  2013cites this paper
• Protective effects of lycopene against methylmercury-induced neurotoxicity in cultured rat cerebellar granule neurons.

  2013cites this paper
• Oxidative stress due to radiation in CD34+ Hematopoietic progenitor cells: protection by IGF-1

  2012cites this paper
• The Prenatal Toxic Effect of Methylmercury on the Development of the Appendicular Skeleton of Rat Fetuses and the Protective Role of Vitamin E

  2012cites this paper
• Role of Calcium and Mitochondria in MeHg-Mediated Cytotoxicity

  2012cites this paper
• Methylmercury-induced changes in target organs of suckling rat pups.

  2012cites this paper
• Mitochondria: omega-3 in the route of mitochondrial reactive oxygen species.

  2012cites this paper
• The effect of methylmercury exposure on early central nervous system development in the zebrafish (Danio rerio) embryo

  2012cites this paper
• Effects of dietary methylmercury on the zebrafish brain: histological, mitochondrial, and gene transcription analyses

  2011cites this paper
• Role of oxidative stress and the mitochondrial permeability transition in methylmercury cytotoxicity.

  2011cites this paper
• Interactions between marine n-3 fatty acids and methylmercury in Atlantic salmon (Salmo salar)

  2011cites this paper
• Mechanisms of Toxicity and the Structure-Activity Relationships of Molinate and Dieldrin

  2011cites this paper
• The effects of methylmercury on the cytokine-signaling and glial differentiation of neural progenitors

  2011cites this paper
• Neuronal Death and Oxidative Stress in the Developing Brain

  2011cites this paper
• Protective effects of organoselenium compounds against methylmercury-induced oxidative stress in mouse brain mitochondrial-enriched fractions.

  2011cites this paper
• Involvement of oxidative stress-mediated ERK1/2 and p38 activation regulated mitochondria-dependent apoptotic signals in methylmercury-induced neuronal cell injury.

  2011cites this paper
• Investigação dos efeitos protetores do selenito de sódio sobre a neurotoxicidade do metilmercúrio em diferentes períodos de desenvolvimento de ratos wistar

  2011cites this paper
• Responses in the brain proteome of Atlantic cod (Gadus morhua) exposed to methylmercury.

  2010cites this paper
• Effects of inorganic selenium administration in methylmercury‐induced neurotoxicity in mouse cerebral cortex

  2010cites this paper
• Molecular and Physiological Responses to Juvenile Traumatic Brain Injury: Focus on Growth and Metabolism

  2010cites this paper
• The roles of cellular reactive oxygen species, oxidative stress and antioxidants in pregnancy outcomes.

  2010cites this paper
• Relative inhibitory potency of molinate and metabolites with aldehyde dehydrogenase 2: implications for the mechanism of enzyme inhibition.

  2010cites this paper
• Effect of Lead on Oxidative Stress, Na+K+ATPase Activity and Mitochondrial Electron Transport Chain Activity of the Brain of Clarias batrachus L.

  2010cites this paper
• Age-dependent Bupivacaine-induced Muscle Toxicity during Continuous Peripheral Nerve Block in Rats

  2009cites this paper
• Protein reactivity of 3,4-dihydroxyphenylacetaldehyde, an endogenous, potential neurotoxin relevant to Parkinson's disease

  2009cites this paper
• Capacidad del Guarumo (Cecropia peltata) como planta fitorremediadora de suelos contaminados con mercurio

  2009cites this paper
• Methylmercury neurotoxicity is associated with inhibition of the antioxidant enzyme glutathione peroxidase.

  2009cites this paper
• Methylmercury inhibits dopaminergic function in rat pup synaptosomes in an age-dependent manner.

  2009cites this paper
• Hitting a moving target: Basic mechanisms of recovery from acquired developmental brain injury

  2009cites this paper
• Chromium III Exposure Inhibits Brain Na+K+ATPase Activity of Clarias batrachus L. Involving Lipid Peroxidation and Deficient Mitochondrial Electron Transport Chain Activity

  2009cites this paper
• Neuroimmune Responses to Toxic Agents: Comparison of Organometal Electrophiles Using Detection of Antibodies to Neural Cytoskeleton and Myelin as Biomarkers

  2008cites this paper
• Characterization of methylmercury demethylation in the central nervous system.

  2008cites this paper
• Low-Intensity Laser Irradiation Improves the Mitochondrial Dysfunction of C2C12 Induced by Electrical Stimulation

  2008cites this paper
• Methylmercury neurotoxicity: Role of oxidative stress

  2007cites this paper
• Lipid peroxidation products inhibit dopamine catabolism yielding aberrant levels of a reactive intermediate.

  2007cites this paper
• Mercurial-induced hydrogen peroxide generation in mouse brain mitochondria: protective effects of quercetin.

  2007cites this paper
• Methylmercury-induced changes in mitochondrial function in striatal synaptosomes are calcium-dependent and ROS-independent.

  2007cites this paper
• UNIVERSIDADE FEDERAL DE SANTA MARIA CENTRO DE CIÊNCIAS DA SAÚDE PROGRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS FARMACÊUTICAS

  2006cites this paper
• Immunotoxicology Specialty Section Newsletter

  2004cites this paper