Efficacy and tolerability of 0.2% brimonidine tartrate for the treatment of acute non-arteritic anterior ischemic optic neuropathy (NAION): a 3-month, double-masked, randomised, placebo-controlled trial

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Graefe's Archive for Clinical and Experimental Ophthalmology

• Publication date

  2006-05-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1007/s00417-005-0102-8PMID 16151785
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Vorschlag für die funktionelle Bewertung von Gesichtsfeldausfällen mit einem Punktesystem

  2004cited by this paper
• [Proposed scoring system for assessment of functional impairment due to visual field defects].

  2004cited by this paper
• Ischemic optic neuropathies

  2004cited by this paper
• Role of alpha-2 agonists in neuroprotection.

  2003cited by this paper
• Alpha-2 adrenoceptor agonist protects retinal function after acute retinal ischemic injury in the rat

  2002cited by this paper
• Distribution of brimonidine into anterior and posterior tissues of monkey, rabbit, and rat eyes.

  2002cited by this paper
• Vitreous concentration of topically applied brimonidine tartrate 0.2%.

  2001cited by this paper
• Role of alpha-2 adrenergic receptors in neuroprotection and glaucoma.

  2001cited by this paper
• Automatisierter Swinging-flashlight-Test bei Patienten mit Sehnervenerkrankungen

  2001cited by this paper
• Ischemic optic neuropathies.

  2001cited by this paper
• Neuroprotection of retinal ganglion cells by brimonidine in rats with laser-induced chronic ocular hypertension.

  2001cited by this paper
• The Neurology of Vision

  2001cited by this paper
• [Automated swinging flashlight test in patients with optic nerve diseases].

  2001cited by this paper
• Alpha-2 Adrenergic Receptor Agonists are Neuroprotective in Experimental Models of Glaucoma

  2001cited by this paper
• RGC death in mice after optic nerve crush injury: oxidative stress and neuroprotection.

  2000cited by this paper
• Ischaemic optic neuropathy.

  2000cited by this paper
• Levodopa may improve vision loss in recent-onset, nonarteritic anterior ischemic optic neuropathy.

  2000cited by this paper
• Role of aspirin in reducing the frequency of second eye involvement in patients with non-arteritic anterior ischaemic optic neuropathy.

  2000cited by this paper
• From the Lab to the Clinic: Activation of an Alpha-2 agonist Pathway is Neuroprotective in Models of Retinal and Optic Nerve Injury

  1999cited by this paper
• Role of aspirin in reducing the frequency of second eye involvement in patients with non-arteritic anterior ischaemic optic neuropathy

  1999cited by this paper
• Alpha2-adrenoreceptor agonists are neuroprotective in a rat model of optic nerve degeneration.

  1999cited by this paper
• Aspirin Reduces the Incidence of Second Eye NAION: A Retrospective Study

  1997cited by this paper
• Pain in Anterior Ischemic Optic Neuropathy

  1995cited by this paper
• Optic nerve decompression surgery for nonarteritic anterior ischemic optic neuropathy (NAION) is not effective and may be harmful. The Ischemic Optic Neuropathy Decompression Trial Research Group.

  1995cited by this paper
• Comparative ocular pharmacokinetics of brimonidine after a single dose application to the eyes of albino and pigmented rabbits.

  1995cited by this paper
• Painful ophthalmoplegia associated with lymphoid hyperplasia of the nasopharynx

  1995cited by this paper
• [Non-arteritic anterior ischemic optic neuropathy: long-term results after hemodilution therapy].

  1994cited by this paper
• Nichtarteriitische vordere ischämische Optikusneuropathie: Langzeitergebnisse nach Hämodilutionstherapie

  1994cited by this paper
• [Hemodilution therapy in patients with acute anterior ischemic optic neuropathy].

  1993cited by this paper
• Systemische Kortikosteroidtherapie bei nicht-arteriitischer anteriorer ischämischer Optikusneuropathie

  1992cited by this paper
• [Systemic corticosteroid therapy in non-arteritic anterior ischemic optic neuropathy].

  1992cited by this paper
• Progressive anterior ischemic optic neuropathy due to giant cell arteritis despite high-dose intravenous corticosteroids.

  1988cited by this paper
• Progression of visual defects in ischemic optic neuropathy.

  1988cited by this paper

• Effect of Brimonidine on Retinal Ganglion Cell Function by in vivo Calcium Imaging of Optic Nerve Crush in Mice.

  2025cites this paper
• A Randomized Sham-Controlled Phase 2/3 Trial of QPI-1007 for Acute Nonarteritic Anterior Ischemic Optic Neuropathy.

  2025cites this paper
• Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients Prescribed Semaglutide

  2024cites this paper
• Use of brimonidine tartrate eye drops after nonarteritic anterior ischemic optic neuropathy event: Case series

  2024cites this paper
• Effect of Intraocular Pressure Lowering Treatment on Peripapillary and Macular Vessel Density on Normotensive Eyes with Optic Disc Drusen: A Randomized Controlled Trial

  2024cites this paper
• ANATOMICAL AND FUNCTIONAL OUTCOME IN THE MANAGEMENT OF NON-ARTERITIC ANTERIOR ISCHEMIC OPTIC NEUROPATHY

  2024cites this paper
• Review of evidence for treatments of acute non arteritic anterior ischemic optic neuropathy

  2024cites this paper
• Ischemic Optic Neuropathy: A Review of Current and Potential Future Pharmacotherapies

  2024cites this paper
• A combination of topical and systemic administration of brimonidine is neuroprotective in the murine optic nerve crush model

  2024cites this paper
• Intravitreal Aflibercept for Patients with Acute Nonarteritic Anterior Ischemic Optic Neuropathy: A Retrospective Trial

  2023cites this paper
• Non-Arteritic Anterior Ischemic Optic Neuropathy (NA-AION): A Comprehensive Overview

  2023cites this paper
• Nichtarteriitische anteriore ischämische Optikusneuropathie (nAION)

  2023cites this paper
• Neuroprotection in neurodegenerations of the brain and eye: Lessons from the past and directions for the future

  2022cites this paper
• Non-Arteritic Anterior Ischemic Optic Neuropathy: Challenges for the Future

  2022cites this paper
• Efficacy of Treatments in Nonarteritic Ischemic Optic Neuropathy: A Systematic Review and Meta-Analysis

  2022cites this paper
• Treatment of nonarteritic anterior ischemic optic neuropathy with an endothelin antagonist: ENDOTHELION (ENDOTHELin antagonist receptor in Ischemic Optic Neuropathy)—a multicentre randomised controlled trial protocol

  2022cites this paper
• Optic nerve neuropathies – causative factors, methods of diagnostics, current and future possibilities of treatment

  2022cites this paper
• Ocular Pharmacokinetics of Brimonidine Drug Delivery System in Monkeys and Translational Modeling for Selection of Dose and Frequency in Clinical Trials

  2021cites this paper
• Intravitreal Injection Of The Granulocyte-Colony Stimulating Factor For The Treatment Of Non-Arteritic Anterior Ischemic Optic Neuropathy: A Pilot Study

  2021cites this paper
• Correlations between visual morphological, electrophysiological, and acuity changes in chronic non-arteritic ischemic optic neuropathy

  2021cites this paper
• Non-Arteritic Anterior Ischemic Optic Neuropathy

  2021cites this paper
• Bilateral Sequential Non-arteritic Anterior Ischemic Optic Neuropathy (NAION)

  2021cites this paper
• The Role of Adrenoceptors in the Retina

  2020cites this paper
• [Acute ischemic optic nerve disease: Pathophysiology, clinical features and management (French translation of the article)].

  2020cites this paper
• Acute ischemic optic nerve disease: Pathophysiology, clinical features and management.

  2020cites this paper
• The effect of systemic erythropoietin and oral prednisolone on recent-onset non-arteritic anterior ischemic optic neuropathy: a randomized clinical trial

  2020cites this paper
• Evaluation of enhanced external counterpulsation therapy for nonarteritic anterior ischemic optic neuropathy

  2020cites this paper
• Neuroenhancement and neuroprotection by oral solution citicoline in non-arteritic ischemic optic neuropathy as a model of neurodegeneration: A randomized pilot study

  2019cites this paper
• Randomized Controlled Phase 2a Study of RPh201 in Previous Nonarteritic Anterior Ischemic Optic Neuropathy.

  2019cites this paper
• Treatment of Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION)

  2019cites this paper
• Neuro-protection and neuro-regeneration of the optic nerve: recent advances and future directions.

  2019cites this paper
• Disc Configuration as a Risk and Prognostic Factor in NAION: The Impact of Cup to Disc Ratio, Disc Diameter, and Crowding Index

  2019cites this paper
• Neuroprotection in Optic Neuropathy

  2018cites this paper
• New Treatments for Nonarteritic Anterior Ischemic Optic Neuropathy.

  2017cites this paper
• Nonarteritic anterior ischemic optic neuropathy: cause, effect, and management

  2017cites this paper
• Pharmacologic Therapy of Ocular Disease

  2017cites this paper
• Biocompatibility of intravitreal injection of human mesenchymal stem cells in immunocompetent rabbits

  2017cites this paper
• Management of ischemic optic neuropathies

  2017cites this paper
• Ocular Hypotensives and Neuroprotectants in Glaucoma

  2016cites this paper
• Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION): A Review and Update on Animal Models

  2016cites this paper
• Carbon monoxide treatment reduces microglial activation in the ischemic rat retina

  2016cites this paper
• The effect of high-dose steroids, and normobaric oxygen therapy, on recent onset non-arteritic anterior ischemic optic neuropathy: a randomized clinical trial

  2016cites this paper
• Intravitreal Injection of a Rho‐Kinase Inhibitor (Fasudil) for Recent‐Onset Nonarteritic Anterior Ischemic Optic Neuropathy

  2016cites this paper
• Translational Pharmacology in Glaucoma Neuroprotection.

  2016cites this paper
• Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation.

  2016cites this paper
• Is there treatment for nonarteritic anterior ischemic optic neuropathy

  2015cites this paper
• 55 – Alpha Agonists

  2015cites this paper
• Die nicht arteriitische anteriore ischämische Optikusneuropathie (NAION)

  2015cites this paper
• Trans-meningeal drug delivery to optic nerve ganglion cell axons using a nanoparticle drug delivery system.

  2014cites this paper
• Efficacy of granulocyte-colony stimulating factor treatment in a rat model of anterior ischemic optic neuropathy

  2014cites this paper
• Translational Preclinical Research may Lead to Improved Medical Management of Non-Arteritic Anterior Ischemic Optic Neuropathy

  2014cites this paper
• Visual outcome of mega-dose intravenous corticosteroid treatment in non-arteritic anterior ischemic optic neuropathy – retrospective analysis

  2014cites this paper
• The Role of Peroxisome Proliferator-Activated Receptor and Effects of Its Agonist, Pioglitazone, on a Rat Model of Optic Nerve Crush: PPARγ in Retinal Neuroprotection

  2013cites this paper
• Intravitreal bevacizumab for the treatment of nonarteritic anterior ischemic optic neuropathy: a prospective trial

  2013cites this paper
• Neuroprotective effects of topical CB1 agonist WIN 55212-2 on retinal ganglion cells after acute rise in intraocular pressure induced ischemia in rat.

  2013cites this paper
• Nonarteritic anterior ischemic optic neuropathy: untreatable at present?

  2013cites this paper
• Treatment strategy for non-arteritic anterior ischemic optic neuropathy

  2013cites this paper
• Protecting the retinal neurons from glaucoma: lowering ocular pressure is not enough.

  2012cites this paper
• How Should Patients With Indirect Traumatic Optic Neuropathy Be Treated?

  2011cites this paper
• Memantine Treatment in Acute Nonarteritic Anterior Ischemic Optic Neuropathy: A Randomized Clinical Trial

  2011cites this paper
• Neuroprotection in glaucoma

  2011cites this paper
• Neuroprotection in Glaucoma

  2011cites this paper
• Glaucomatous Versus Nonglaucomatous Visual Loss: The Neuro-Ophthalmic Perspective

  2010cites this paper
• Treatment of nonarteritic anterior ischemic optic neuropathy.

  2010cites this paper
• Neuroprotective agents in glaucoma therapy: recent developments and future directions

  2010cites this paper
• Two presentations of nonarteritic ischemic optic neuropathy.

  2010cites this paper
• Intravitreal erythropoietin injection for the treatment of non-arteritic anterior ischaemic optic neuropathy

  2010cites this paper
• Chapter 41 – Ischemic optic neuropathy

  2010cites this paper
• Neuroprotection: extrapolating from neurologic diseases to the eye.

  2009cites this paper
• [Emergencies in ophthalmology].

  2009cites this paper
• Non-arteritic anterior ischemic optic neuropathy (NA-AION) after intravitreal injection of bevacizumab (Avastin®) for treatment of angoid streaks in pseudoxanthoma elasticum

  2009cites this paper
• Experimental and clinical evidence for brimonidine as an optic nerve and retinal neuroprotective agent: an evidence-based review.

  2009cites this paper
• Possible neuroprotective effect of brimonidine in a mouse model of ischaemic optic neuropathy

  2009cites this paper
• Ischemic Optic Neuropathy

  2009cites this paper
• Brimonidin Retinal Gangliyon Hücrelerinin Kaybolmuş Fonksiyonlarına Faydalı Olabilir mi

  2009cites this paper
• A Critical Discussion of the Rates of Progression and Causes of Optic Nerve Damage in Glaucoma: International Glaucoma Think Tank II: July 25-26, 2008, Florence, Italy

  2009cites this paper
• Non-arteritic anterior ischaemic optic neuropathy: a review and update.

  2009cites this paper
• Nonarteritic anterior ischaemic optic neuropathy

  2008cites this paper
• Ischemic optic neuropathy

  2008cites this paper
• The Ischemic Optic Neuropathies

  2008cites this paper
• Stroke and visual loss

  2008cites this paper
• Ischemic Optic Neuropathies

  2008cites this paper
• Cytidine‐5′‐diphosphocholine (Citicoline): a pilot study in patients with non‐arteritic ischaemic optic neuropathy

  2008cites this paper
• Axonal loss and neuroprotection in optic neuropathies.

  2007cites this paper
• Neuroprotective effects of brimonidine treatment in a rodent model of ischemic optic neuropathy.

  2007cites this paper
• Ischemic Optic Neuropathies

  2007cites this paper
• The Prevalence of Relative Afferent Pupillary Defects in Normal Subjects

  2007cites this paper
• Phosphodiesterase type 5 inhibitors, visual changes, and nonarteritic anterior ischemic optic neuropathy: Is there a link?

  2007cites this paper
• Nonarteritic anterior ischemic optic neuropathy

  2005cites this paper
• Ischemic optic neuropathies

  2004cites this paper
• Ischemic Optic Neuropathy

  2004cites this paper
• A Pilot Study of Topical Treatment with an alpha2-agonist in Patients with Retinal Dystrophies

  2003cites this paper
• Brimonidine in the treatment of glaucoma and ocular hypertension

  1997cites this paper