Differentiation of early-stage parkinsonisms using neuromelanin-sensitive magnetic resonance imaging.

No abstract is available for this paper.

• Publication year

  2014

• Venue

  Parkinsonism & Related Disorders

• Publication date

  2014-07-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/j.parkreldis.2014.04.005PMID 24768616
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2009cited by this paper
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  2008cited by this paper
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  2008cited by this paper
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  2007cited by this paper
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  2006cited by this paper
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  2005cited by this paper
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  2002cited by this paper
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  1999cited by this paper
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  1999cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1998cited by this paper
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  1997cited by this paper
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  1996cited by this paper
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  1994cited by this paper
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  1992cited by this paper

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