Discovery of the Potent and Selective M1 PAM-Agonist N-[(3R,4S)-3-Hydroxytetrahydro-2H-pyran-4-yl]-5-methyl-4-[4-(1,3-thiazol-4-yl)benzyl]pyridine-2-carboxamide (PF-06767832): Evaluation of Efficacy and Cholinergic Side Effects.

J. Davoren,Chewah Lee,M. Garnsey,M. Brodney,Jason S. Cordes,Keith Dlugolenski,J. Edgerton,A. Harris,Christopher J. Helal,S. Jenkinson,Gregory W. Kauffman,T. Kenakin,John T. Lazzaro,S. Lotarski,Yuxia Mao,D. Nason,C. Northcott,Lisa M. Nottebaum,S. O'neil,Betty A Pettersen,M. Popiolek,V. Reinhart,Romelia Salomón-Ferrer,Stefanus J. Steyn,Damien Webb,Lei Zhang,S. Grimwood

Published 2016 in Journal of Medicinal Chemistry

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