3-MCPD: A Worldwide Problem of Food Chemistry

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Critical reviews in food science and nutrition

• Publication date

  2016-10-25

• Fields of study

  Agricultural and Food Sciences, Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1080/10408398.2013.829414PMID 25830907
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Effects of yeast stress and organic acids on chloropropanols formation in cereal products

  2018cited by this paper
• Determination of free and bound 3-chloropropane-1,2-diol by gas chromatography with mass spectrometric detection using deuterated 3-chloropropane-1,2-diol as internal standard

  2018cited by this paper
• Analysis of the lipid fractions of coffee creamers, cream aerosols, and bouillon cubes for their health risk associated constituents

  2018cited by this paper
• 3-Chloropropane-1,2-diol Fatty Acid Esters in Potato Products

  2018cited by this paper
• Free and bound 3 -chloropropane -1,2 -diol in coffee surrogates and malts

  2018cited by this paper
• Chloropropanols and their esters in cereal products

  2018cited by this paper
• A new, direct analytical method using LC-MS/MS for fatty acid esters of 3-chloro-1,2-propanediol (3-MCPD esters) in edible oils

  2013cited by this paper
• Optimization of palm oil physical refining process for reduction of 3-monochloropropane-1,2-diol (3-MCPD) ester formation.

  2013cited by this paper
• Influence of chloride and glycidyl-ester on the generation of 3-MCPD- and glycidil-esters

  2013cited by this paper
• Evaluation of an Improved Indirect Method for the Analysis of 3-MCPD Esters Based on Acid Transesterification

  2012cited by this paper
• The effects of physical refining on the formation of 3-monochloropropane-1,2-diol esters in relation to palm oil minor components.

  2012cited by this paper
• High-throughput and sensitive analysis of 3-monochloropropane-1,2-diol fatty acid esters in edible oils by supercritical fluid chromatography/tandem mass spectrometry.

  2012cited by this paper
• Relative oral bioavailability of 3-MCPD from 3-MCPD fatty acid esters in rats

  2012cited by this paper
• Dispersive microextraction based on water-coated Fe₃O₄ followed by gas chromatography-mass spectrometry for determination of 3-monochloropropane-1,2-diol in edible oils.

  2012influential reference
• Toxicological assessment of 3-chloropropane-1,2-diol and glycidol fatty acid esters in food.

  2011cited by this paper
• Bidirectional Conversion Between 3-Monochloro-1,2-propanediol and Glycidol in Course of the Procedure of DGF Standard Methods

  2011cited by this paper
• Monitoring cyclic acyloxonium ion formation in palmitin systems using infrared spectroscopy and isotope labelling technique

  2011cited by this paper
• What do we know about the molecular mechanism of 3‐MCPD ester formation?

  2011cited by this paper
• Combined solid-phase extraction and gas chromatography-mass spectrometry used for determination of chloropropanols in water.

  2011cited by this paper
• Determination of chloropropanols in foods by one-step extraction and derivatization using pressurized liquid extraction and gas chromatography-mass spectrometry.

  2011cited by this paper
• Determination of 3-MCPD esters in edible oil – methods of analysis and comparability of results

  2011cited by this paper
• Determination of bound 2,3-epoxy-1-propanol (glycidol) and bound monochloropropanediol (MCPD) in refined oils

  2011cited by this paper
• Lipolysis – A highly regulated multi-enzyme complex mediates the catabolism of cellular fat stores

  2011cited by this paper
• On the necessity of edible oil refining and possible sources of 3‐MCPD and glycidyl esters

  2011cited by this paper
• An initial study on the formation of 3-MCPD esters during oil refining

  2011cited by this paper
• Removal of 3-MCPD esters and related substances after refining by adsorbent material

  2011cited by this paper
• Formation and occurrence of esters of 3‐chloropropane‐1,2‐diol (3‐CPD) in foods: What we know and what we assume

  2011cited by this paper
• Fatty acid esters of chloropropanols and related compounds in food: Toxicological aspects

  2011cited by this paper
• Critical factors of indirect determination of 3-chloropropane-1,2-diol esters

  2011cited by this paper
• Fatty acid esters of 3-MCPD: Overview of occurrence and exposure estimates

  2011cited by this paper
• Direct Determination of MCPD Fatty Acid Esters and Glycidyl Fatty Acid Esters in Vegetable Oils by LC–TOFMS

  2010cited by this paper
• Proficiency Test on the Determination of 3-MCPD Esters in Edible Oil - Final Report

  2010cited by this paper
• Carcinogenicity study of 3-monochloropropane-1, 2-diol (3-MCPD) administered by drinking water to B6C3F1 mice showed no carcinogenic potential

  2010cited by this paper
• Enzymatic removal of 3‐monochloro‐1,2‐propanediol (3‐MCPD) and its esters from oils

  2010cited by this paper
• 3-MCPD in food other than soy sauce or hydrolysed vegetable protein (HVP)

  2010cited by this paper
• 3-MCPD esters in food products. Summary Report of a Workshop held in February 2009 in Brussels, Belgium.

  2009cited by this paper
• A Novel Derivatization Method Coupled with GC–MS for the Simultaneous Determination of Chloropropanols

  2009cited by this paper
• Occurrence of 3-chloropropane-1,2-diol fatty acid esters in infant and baby foods

  2009cited by this paper
• Chloropropanols levels in foodstuffs marketed in Hong Kong

  2008cited by this paper
• Occurrence of 3-MCPD fatty acid esters in human breast milk

  2008cited by this paper
• Esters of 3-chloro-1,2-propanediol (3-MCPD) in vegetable oils: Significance in the formation of 3-MCPD

  2008cited by this paper
• Subchronic toxicity study of 3-monochloropropane-1,2-diol administered by drinking water to B6C3F1 mice.

  2008cited by this paper
• Carcinogenicity study of 3-monochloropropane-1,2-diol in Sprague-Dawley rats.

  2008cited by this paper
• Determination of 1,3-dichloro-2-propanol and 3-chloro-1,2-propandiol in soy sauce by headspace derivatization solid-phase microextraction combined with gas chromatography-mass spectrometry.

  2007cited by this paper
• Intestinal Monoacylglycerol Metabolism

  2007cited by this paper
• An improved high‐pressure homogenizer for making fine emulsions on a small scale

  2007cited by this paper
• The smoking process - : A potent source of 3-chloropropane-1,2-diol (3-MCPD) in meat products

  2006cited by this paper
• The simultaneous separation and determination of chloropropanols in soy sauce and other flavoring with gas chromatography-mass spectrometry in negative chemical and electron impact ionization modes

  2006cited by this paper
• Fatty acid esters of 3-chloropropane-1,2-diol in edible oils

  2006cited by this paper
• Lack of effect on rat testicular organogenesis after in utero exposure to 3-monochloropropane-1,2-diol (3-MCPD).

  2006cited by this paper
• Occurrence of 3-chloropropane-1,2-diol and its esters in coffee

  2005cited by this paper
• Determination of 3-chloropropane-1,2-diol as its 1,3-dioxolane derivative at the μg kg−1 level: Application to a wide range of foods

  2005cited by this paper
• Influence of dough ingredients on 3-chloropropane-1,2-diol (3-MCPD) formation in toast

  2005cited by this paper
• Determination of 3-Chloropropane-1,2-diol in Liquid Hydrolyzed Vegetable Proteins and Soy Sauce by Solid-Phase Microextraction and Gas Chromatography/Mass Spectrometry

  2005cited by this paper
• Generation of monochloropropanediols (MCPDs) in model dough systems. 1. Leavened doughs.

  2004cited by this paper
• Generation of monochloropropanediols (MCPDs) in model dough systems. 2. Unleavened doughs.

  2004cited by this paper
• Model studies on the formation of monochloropropanediols in the presence of lipase.

  2004cited by this paper
• 3-MCPD: Occurrence in bread crust and various food groups as well as formation in toast

  2003cited by this paper
• 3-Monochloropropane-1,2-diol (3-MCPD) in food ingredients from UK food producers and ingredient suppliers

  2002cited by this paper
• Sensitive method for the determination of 1,3-dichloropropan-2-ol and 3-chloropropane-1,2-diol in soy sauce by capillary gas chromatography with mass spectrometric detection.

  2002cited by this paper
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  2002cited by this paper
• Survey of 3-monochloropropane-1,2-diol (3-MCPD) in selected food groups, 1999-2000

  2002cited by this paper
• The effects of domestic cooking on the levels of 3-monochloropropanediol in foods

  2001cited by this paper
• Safety evaluation of certain food additives and contaminants

  2000cited by this paper
• Some industrial chemicals

  2000cited by this paper
• Determination of halogenated mono-alcohols and diols in water by gas chromatography with electron-capture detection.

  2000cited by this paper
• Sensitive method for the determination of 3-chloropropane-1,2-diol and 2-chloropropane-1,3-diol by capillary gas chromatography with mass spectrometric detection

  1998cited by this paper
• Determination of the Chloropropanols, 3-Chloro-1,2-propandiol and 2-Chloro-1,3-propandiol, in Hydrolysed Vegetable Proteins and Seasonings by Gas Chromatography/Ion Trap Tandem Mass Spectrometry

  1997cited by this paper
• Inhibition of glycolysis in boar spermatozoa by alpha-chlorohydrin phosphate appears to be mediated by phosphatase activity.

  1995cited by this paper
• Microbial dehalogenation of haloaliphatic compounds

  1994cited by this paper
• Determination of 3-chloropropane-1,2-diol in hydrolysed vegetable proteins by capillary gas chromatography with electrolytic conductivity detection

  1993cited by this paper
• Bestimmung von Dichlorpropanolen und Monochlorpropandiolen in Würzen und würzehaltigen Lebensmitteln

  1991cited by this paper
• Determination of 3-chloropropane-1,2-diol in liquid hydrolysed vegetable proteins by capillary gas chromatography with flame ionization detection

  1991cited by this paper
• Mechanism of formation of chloropropanols present in protein hydrolysates

  1991cited by this paper
• Toxicological evaluation of certain food additives and contaminants

  1987cited by this paper
• Gas-liquid chromatography of 3-chloropropanediol.

  1986cited by this paper
• Occurrence of diesters of 3-chloro-1,2-propanediol in the neutral lipid fraction of goats' milk

  1984cited by this paper
• Isolation and identification of C16 and C18 fatty acid esters of chloropropanediol in adulterated Spanish cooking oils

  1983cited by this paper
• Antifertility actions of alpha-chlorohydrin in the male.

  1983cited by this paper
• Antifertility actions of alpha-chlorohydrin in the male.

  1983cited by this paper
• Mutagenicity of glycerol chlorohydrines and of their esters with higher fatty acids present in protein hydrolysates.

  1982cited by this paper
• Glycerol chlorohydrins and their esters as products of the hydrolysis of tripalmitin, tristearin and triolein with hydrochloric acid

  1980cited by this paper
• Some preliminary observations of the nephrotoxicity of the male antifertility drug (+/-)alpha-chlorohydrin.

  1980cited by this paper
• Some preliminary observations of the nephrotoxicity of the male antifertility drug (±)α‐chlorohydrin

  1980cited by this paper
• The antifertility actions of alpha-chlorohydrin in the male.

  1978cited by this paper
• The Oxidative Metabolism of α-Chlorohydrin in the Male Rat and the Formation of Spermatocoeles

  1978cited by this paper
• Chlorohydrins in protein hydrolysates

  1978cited by this paper
• The oxidative metabolism of alpha-chlorohydrin in the male rat and the formation of spermatocoeles.

  1978cited by this paper
• The antifertility actions of α-chlorohydrin in the male

  1978cited by this paper
• The entry of alpha-chlorohydrin into body fluids of male rats and its effect upon the incorporation of glycerol into lipids.

  1975cited by this paper
• Carcinogenic activity of alkylating agents.

  1974cited by this paper
• Male antifertility compounds: efficacy of U-5897 in primates (Macacamulatta).

  1970cited by this paper

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